LOCUS       XM_039104378            1625 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus prostaglandin I2 synthase (Ptgis),
            transcript variant X1, mRNA.
ACCESSION   XM_039104378
VERSION     XM_039104378.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039104378.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1625
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1625
                     /gene="Ptgis"
                     /gene_synonym="PGIS"
                     /note="prostaglandin I2 synthase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 24
                     ESTs, 11 long SRA reads, 4 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 8 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:25527"
                     /db_xref="RGD:3438"
     CDS             16..1488
                     /gene="Ptgis"
                     /gene_synonym="PGIS"
                     /codon_start=1
                     /product="prostacyclin synthase isoform X1"
                     /protein_id="XP_038960306.1"
                     /db_xref="GeneID:25527"
                     /db_xref="RGD:3438"
                     /translation="MLAHIYISKLQLHEWRPGEPPLDLGSIPWLGHALEFGKDAASFL
                     TRMKEKHGDIFTVLVGGRYVTVLLDPHSYDTVVWDLRTRLDFHPYAIFLMERIFDLQL
                     PNFNPSEEKARMKPTLMHKDLQALTEAMYTNLRTVLLGDSTEGGSGWQEKGLLEFSYS
                     SLLSAGYLTLYGVEASPRTHESQALDRDHSADVFRTFRQLDLMLPKLARGSLSVGDKD
                     HACSVKSRLWKLLSPAGLASRADRSSWLESYLRHLEEMGVSEDMQARALVLQLWATQG
                     NMGPTAFWLLLFLLKNPEALDAVHAELKRIVWQAEKPVLQMTALPQKILDSMPVLDSV
                     LNETLRLTAAPFITREVMADLALPMADRREFSLRRGDRLLLFPFLSPQKDPEIYTEPE
                     VFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNQCLGKSYAINSIKQFVVLLLT
                     HFDLELVSEDTEVPEFDLSRYGFGLMQPEEDVPIRYRTRL"
ORIGIN      
        1 ccaggcctgg tcaacatgct ggctcatata tatatatcaa agctacagct tcatgaatgg
       61 cgacccggtg agcctccgtt ggacctgggc agcatcccct ggctgggcca tgccttggag
      121 tttgggaagg atgccgccag cttccttacc aggatgaagg agaagcacgg tgacatattt
      181 actgtgctgg tggggggcag gtatgtcact gtcctcctgg acccacactc ttacgacaca
      241 gtggtgtggg atctgcgtac acggctggac ttccacccct acgccatctt cctcatggag
      301 aggatttttg atctgcagct tccaaatttc aaccccagcg aggagaaggc caggatgaag
      361 ccgacgctca tgcacaaaga cctgcaggcg ctcacggaag ccatgtatac caacctgcgc
      421 accgtcctgc tgggtgactc cacagaagga ggcagtggct ggcaggagaa aggtctgctt
      481 gagttctcct acagctccct gctcagcgct ggctacctga ccctgtatgg agtggaggcc
      541 tcaccacgca cccacgagag tcaggccctc gaccgtgacc actcagccga cgttttccgc
      601 accttccgcc agctggatct gatgctcccc aaactggctc gaggctcctt gtcagtgggg
      661 gataaagacc atgcatgcag tgtcaaaagc cgcctgtgga agctgctgtc tccagccgga
      721 ctggcctcca gggctgaccg gagcagctgg ttggagagtt acctgagaca tcttgaggag
      781 atgggggtat cagaggacat gcaggcccgg gcactggtgc tgcagctctg ggccacacaa
      841 gggaatatgg gacccacggc tttctggctc ctcctcttcc tcctcaagaa cccggaagcc
      901 ctcgatgctg tccatgcaga gctgaaacgc atcgtctggc aagcagagaa gcctgtttta
      961 cagatgaccg cactcccgca gaagattcta gacagcatgc ctgtgctaga cagtgtgctc
     1021 aatgagaccc tccggctcac ggccgccccc ttcatcaccc gtgaggtcat ggcagacctg
     1081 gccttgccta tggcagacag gagggaattc tctcttcgac gcggtgaccg ccttctcctc
     1141 tttcctttcc tgagtcccca gaaggaccca gaaatctaca cagaacctga agtctttaaa
     1201 tacaaccggt tcttgaaccc agatgggtca gaaaagaaag atttttacaa agatgggaaa
     1261 cggctaaaga attacaacat gccttggggc gcagggcaca accagtgcct ggggaagagc
     1321 tatgccatca acagcatcaa acagtttgtg gtcctgctgc tgactcattt cgacctggag
     1381 ctggtcagtg aggacacaga ggtcccggag tttgacctta gcagatatgg ctttggcctg
     1441 atgcagccgg aggaagatgt gcccatccgg taccgtacca ggctgtgacc tgtggagcag
     1501 acactacact catctggggc ctcctgactt cctgttgttc ctccagaatg ctgtgtccag
     1561 aggaggggac agtgagaaca ccgagagcag gaaaagctaa taaaagctct gtgtctcgct
     1621 gtgaa
//
