LOCUS       NM_019243               5812 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus prostaglandin F2 receptor inhibitor (Ptgfrn),
            mRNA.
ACCESSION   NM_019243 XM_346636
VERSION     NM_019243.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5812)
  AUTHORS   Charrin,S., Latil,M., Soave,S., Polesskaya,A., Chretien,F.,
            Boucheix,C. and Rubinstein,E.
  TITLE     Normal muscle regeneration requires tight control of muscle cell
            fusion by tetraspanins CD9 and CD81
  JOURNAL   Nat Commun 4, 1674 (2013)
   PUBMED   23575678
REFERENCE   2  (bases 1 to 5812)
  AUTHORS   Teckchandani,A., Toida,N., Goodchild,J., Henderson,C., Watts,J.,
            Wollscheid,B. and Cooper,J.A.
  TITLE     Quantitative proteomics identifies a Dab2/integrin module
            regulating cell migration
  JOURNAL   J Cell Biol 186 (1), 99-111 (2009)
   PUBMED   19581412
REFERENCE   3  (bases 1 to 5812)
  AUTHORS   Charrin,S., Le Naour,F., Oualid,M., Billard,M., Faure,G.,
            Hanash,S.M., Boucheix,C. and Rubinstein,E.
  TITLE     The major CD9 and CD81 molecular partner. Identification and
            characterization of the complexes
  JOURNAL   J Biol Chem 276 (17), 14329-14337 (2001)
   PUBMED   11278880
REFERENCE   4  (bases 1 to 5812)
  AUTHORS   Orlicky,D.J., Lieber,J.G., Morin,C.L. and Evans,R.M.
  TITLE     Synthesis and accumulation of a receptor regulatory protein
            associated with lipid droplet accumulation in 3T3-L1 cells
  JOURNAL   J Lipid Res 39 (6), 1152-1161 (1998)
   PUBMED   9643346
REFERENCE   5  (bases 1 to 5812)
  AUTHORS   Orlicky,D.J. and Nordeen,S.K.
  TITLE     Cloning, sequencing and proposed structure for a prostaglandin F2
            alpha receptor regulatory protein
  JOURNAL   Prostaglandins Leukot Essent Fatty Acids 55 (4), 261-268 (1996)
   PUBMED   8951995
REFERENCE   6  (bases 1 to 5812)
  AUTHORS   Orlicky,D.J., Berry,R. and Sikela,J.M.
  TITLE     Human chromosome 1 localization of the gene for a prostaglandin
            F2alpha receptor negative regulatory protein
  JOURNAL   Hum Genet 97 (5), 655-658 (1996)
   PUBMED   8655148
REFERENCE   7  (bases 1 to 5812)
  AUTHORS   Fekkes,D., Bode,W.T., Zijlstra,F.J. and Pepplinkhuizen,L.
  TITLE     Eicosanoid and amino acid metabolism in transient acute psychoses
            with psychedelic symptoms
  JOURNAL   Prostaglandins Leukot Essent Fatty Acids 54 (4), 261-264 (1996)
   PUBMED   8804122
REFERENCE   8  (bases 1 to 5812)
  AUTHORS   Orlicky,D.J.
  TITLE     Negative regulatory activity of a prostaglandin F2 alpha receptor
            associated protein (FPRP)
  JOURNAL   Prostaglandins Leukot Essent Fatty Acids 54 (4), 247-259 (1996)
   PUBMED   8804121
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 26, 2020 this sequence version replaced NM_019243.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U26595.1, SRR26643298.12598.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760400,
                                           SAMN12840107 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-87                JAXUCZ010000002.1  191233346-191233432 c
            88-456              JAXUCZ010000002.1  191203536-191203904 c
            457-870             JAXUCZ010000002.1  191200451-191200864 c
            871-1251            JAXUCZ010000002.1  191196154-191196534 c
            1252-1677           JAXUCZ010000002.1  191180039-191180464 c
            1678-2097           JAXUCZ010000002.1  191175590-191176009 c
            2098-2205           JAXUCZ010000002.1  191170226-191170333 c
            2206-2511           JAXUCZ010000002.1  191163756-191164061 c
            2512-5812           JAXUCZ010000002.1  191158166-191161466 c
FEATURES             Location/Qualifiers
     source          1..5812
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..5812
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /note="prostaglandin F2 receptor inhibitor"
                     /db_xref="GeneID:29602"
                     /db_xref="RGD:3437"
     exon            1..87
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..2678
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /note="prostaglandin F2-alpha receptor regulatory protein;
                     prostaglandin F2-alpha receptor-associated protein;
                     prostaglandin F2 receptor negative regulator; CD9 partner
                     1; glu-Trp-Ile EWI motif-containing protein F"
                     /codon_start=1
                     /product="prostaglandin F2 receptor negative regulator
                     precursor"
                     /protein_id="NP_062116.2"
                     /db_xref="GeneID:29602"
                     /db_xref="RGD:3437"
                     /translation="MGRPAPRPLLLALLSLAVCRGRVVRVPAGTLVRVVGTELVIPCN
                     VSDYDGPSEQNFDWSFSSSGSSFVELASTWEVGFPAQQYRERLQRGDILLRRTANDAV
                     ELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADALVVGPSSRPPPGLSLR
                     EGEPFELRCIASTTSPLHTHLALRWELHRGPVHRSILALSHEGRFHPGPGYEQRYHSG
                     DVRLDTVGSDAYRLSVARALSADQGSYRCVVSEWITEQGSWQEIQEKAVEVATVVIQP
                     TALQLAVPRTVSVTEGKDLDLSCNITTDRVDDVRPEVTWYFKKTPDTSLLASHMLARL
                     DRDSLVHSSPHVALSHVDTRSYHLLVRDVSKENSGYYLCLVALWAPGHNRSWHKVAEA
                     MSAPSGVSVTWLEPEYQVYLNASKVPGFSDDPTELQCRVIDTKRVDAGVRLTVSWYYR
                     MNRRNDDVVASELLAVMDGDWTLRYGERSKQRAQDGEFIFSKEHTDTFSFRIQRTTEE
                     DRGSYYCVVSAWTRQRNSSWVKSKDVFSKPVNIFWASEDSVLVVKARQPKPFFAAGNT
                     FEMTCKVSSKNIKSPRYSVLITAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASR
                     VDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPIGGSLWREAATSLSNPIEID
                     FQTSGPIFNASVHSDTLSVTRGDLIKLFCIVTVDGAVLDPDDMAFDVSWFAVHSFGLD
                     KAPILLSSLDRKGVVTTGQRDWKSTVSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPW
                     VRSPTGSWQREAEIHSRPIFITVKMDVLNAFKYPLLIGVGLSTVIGLLSCLIGYCSSH
                     WCCKKEVRETRRERRRLMSMEMD"
     exon            88..456
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /inference="alignment:Splign:2.1.0"
     exon            457..870
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /inference="alignment:Splign:2.1.0"
     exon            871..1251
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1677
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..2097
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..2205
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /inference="alignment:Splign:2.1.0"
     exon            2206..2511
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /inference="alignment:Splign:2.1.0"
     exon            2512..5812
                     /gene="Ptgfrn"
                     /gene_synonym="CD9P-1; EWI-F"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggaggagga ggcggagagt cgctcccgcc ggccgagcat ggggcgcccg gcgccgaggc
       61 cgctgctgct ggcgctccta tcgctggctg tctgccgcgg gcgtgtggtg agagtccctg
      121 cgggcaccct ggttcgagtg gtgggcactg agctggtgat cccctgcaat gtcagtgact
      181 atgatggccc cagtgagcaa aactttgact ggagcttctc gtcttcggga agcagctttg
      241 tggagctcgc cagcacctgg gaggtgggct tcccggcgca gcagtaccgt gagcggctgc
      301 agcggggcga catcctgttg aggaggacag ccaatgatgc tgtggagctg cacataaaga
      361 atgtccagcc ctcggaccaa ggccactaca agtgttcaac tccaagcaca gacgccaccg
      421 tccagggcaa ctatgaggac acagtgcagg ttaaagtgct ggcagatgcc ctggtggtgg
      481 gccccagctc ccggcctcct ccaggcctga gcctgcgcga gggggagccc tttgaacttc
      541 gatgtatcgc atctactacg tcaccgttgc acacacacct ggcacttcgg tgggaactgc
      601 accgtggccc agtgcaccga agcatcctag ccctaagcca cgagggcagg tttcacccag
      661 gacctggcta tgaacagcgc taccacagtg gggatgtacg cctggacacg gtgggcagcg
      721 atgcctaccg cctctccgta gcccgggcac tctctgcaga ccagggttcc tacagatgtg
      781 tggtcagtga gtggatcaca gagcaaggca gctggcaaga aatccaagaa aaagctgtgg
      841 aagtggccac tgtggtgatc cagccaacag ctctgcaact ggccgtgccc aggacagtgt
      901 ctgtgaccga aggaaaggac ctggaccttt cttgcaacat cacaacagac cgtgtggatg
      961 atgtccggcc tgaggtgaca tggtacttca aaaagacacc cgatacctct ttgcttgcct
     1021 cccatatgct ggctcggctg gaccgtgatt ccctggtaca cagctcacca cacgttgctc
     1081 tcagccacgt ggatacccgc tcttaccatc tactggtgcg agatgttagc aaagaaaact
     1141 ccggttacta tctatgcctc gtggccctct gggctcctgg acacaaccgg agctggcaca
     1201 aggtggcaga ggccatgtct gccccatctg gtgtaagcgt gacctggcta gaaccagaat
     1261 accaggtcta cctgaatgct tctaaggtcc ccgggttttc cgacgacccc acagaactgc
     1321 aatgccgggt gatagacacg aagcgtgtgg atgccggtgt ccgacttact gtgtcgtggt
     1381 actatagaat gaaccgtcgc aatgatgacg tggtggccag cgagcttctc gccgtcatgg
     1441 acggggactg gactctgaga tacggggaga gaagcaaaca gcgggcccag gacggcgagt
     1501 ttatcttttc taaggagcac acagacacat tcagtttccg gatccaaagg actacggagg
     1561 aagacagggg cagttattac tgtgttgtgt ctgcctggac caggcagagg aacagcagct
     1621 gggtgaagag caaagatgtc ttctccaagc ccgtcaacat attctgggcc tcggaagatt
     1681 ctgtgctcgt ggtgaaggca cggcagccaa agcctttctt tgctgcaggg aatacatttg
     1741 agatgacttg caaagtgtct tccaagaata ttaagtctcc acgatactct gttctcatca
     1801 cggctgagaa gcctgttggg gacctctcca gtcccaatga aaccaagtac atcatctccc
     1861 tggaccagga ttccgtggtg aagctggaga actggaccga cgcatctcgg gtggacggcg
     1921 tcgtgttaga gaaggttcaa gaggatgagt tccgataccg aatgtaccag actcaggtct
     1981 ccgatgcggg cctgtaccgc tgcatggtga cagcctggtc tcctatcggg ggcagcttgt
     2041 ggcgagaggc agcgaccagt ctttccaatc ctattgagat tgacttccaa acctcaggtc
     2101 ccatatttaa cgcctctgtg cattcagaca ctctgtccgt cacccgggga gatctcatca
     2161 agttgttctg tatcgtcact gtggacggag cagtgctgga cccagatgac atggccttcg
     2221 atgtatcctg gtttgcagta cactcttttg gcttggacaa ggctcccatc ctcctatcct
     2281 ccttggaccg gaagggagtc gtgactacag gccagaggga ctggaagagt accgtcagcc
     2341 tggagcgagt gagcgtgctg gaatttttgc tgcaagtgca tggctctgag gaccaggact
     2401 ttggcaacta ctattgttct gtgactccct gggtgaggtc accaactggt tcctggcaga
     2461 gggaagccga gatccactcc aggcccatct ttataactgt gaagatggat gtgctgaacg
     2521 ccttcaagta cccgctgctg atcggcgtgg gcctgtccac agtcatcggg ctcctgtcct
     2581 gcctcattgg gtactgcagt tcccattggt gctgtaagaa ggaggtgcgg gagacgcgtc
     2641 gggagcgccg caggctcatg tccatggaga tggattaagc agttggaggg acagaggaac
     2701 gttgtaggag cggtggggtg gggagtgaga agaggactct gagattttac aaccgagtgt
     2761 gttacactaa aaccggtcct ctctaatctc aggtgggact cagcgctctc tcttttctgc
     2821 atgtcaagtt ccgagcgcgg acatgtttac caacacacgg ctcttcttcc cacggcactt
     2881 tctgatatgt aacaatcgag tgtgtgtctc cccccccgct gaagctgttt aatggttaac
     2941 ccccgtctaa ttagttttct cctagcagct tatcgatcct ctgattcacg tgtgttgatc
     3001 acttttgatt taagggatcg cagtgaggaa gggcgaaagc attcagagtt ggtcatcatg
     3061 agtaagaggg tacctgccca cccgaaagcc agcatccaca agcagccatc tggagagctg
     3121 ctacctgctg ctctctaccc tggcccagaa ctgatagaga cctgtgccaa ggcaagctgt
     3181 ggctatgact accctgccca tcccccattg tcaggagttt aaactatatt ggaacctaaa
     3241 ctctataact tcttgacccc ataagccttt tgtttccctt tctcctctac cctcttctgt
     3301 tttcgggttt gtttctgtga gagtgaggat atggcagccc tggagtctag aatttggctt
     3361 tccaccaagc accttatctc gccaccttag ccttaagaat gagtatgaag aaaaatccac
     3421 caccacctct gtccagggca ggtctgtgag gagaggacac tggggaagga aaggcacaga
     3481 tgcttgctta cttgctcact ctgtagttct gaggccgctg tgcctgctcc aggaatccca
     3541 gggtgagtgg gagcagaggg catctgagtt gtgccgctga gccaggtgcc ctgtcccttc
     3601 atgagaggca ctgtcccttg taccccagga ccagcatggg agccacaaat gtgccacatt
     3661 gagctccttc ccaggaaggc agattgctgc ctgccagact gactgacttc aaggaatcag
     3721 aaattgcctg gagcaagcgt gtgttctctg tgaccttttt cagtccttga agtcttttta
     3781 agatccccgc agggggtggt gaagaggggt atactttgtg gacggtttgc tttcctatta
     3841 gaaacacaaa gggaacccag caatttagtg ttatgtgaat ggcctgtaaa ataggattga
     3901 aggcagccgg ctctgcctga ctgggcccag caggaatagg acagagggca ggcacacctt
     3961 ccaggtcacc agtgcctgct ccatcagggc ctcagccatg caaagtctct caccctagca
     4021 tagccttcca ggagcctccg ctaggtactg aggctcatca gccacccggt accctcaccc
     4081 taccctctac ctctgaagga tttaacattg ttgtcttcca aaggggagtg ggggaggaga
     4141 gctcctttct cttaagcaat aaagtaataa gaaaagatgg ccattcacgg gcagctctag
     4201 tcaccatggg accggatgcg ctgagctccc ccctccccac cttctctcca tgtggcccat
     4261 ggtggctttt gtatttgcca cccagtttcc tctgcttgtt tcgagcccac cttggagact
     4321 gctcttatga tgagattctg agccggtggc tctagcccag gtggggtaca ggtttagagt
     4381 cggtagcaag aagagggaca gcaggtgcac cccacacaag caagagaggc cagagaaaga
     4441 ggggaggctt cggaagacat ggctgttcta catgtcgctc tcttattgct agctcagacg
     4501 tgaggcacag gtgactgtac aaacaggaat taggggagta gaaccaagta ttaggaactt
     4561 caagcctgtg ccattactgg agaagattca gggcctttgc agtgcagccc tccttaggag
     4621 gacgagagag atttagcctt ggatgagttg aggtgagccc tagctgtaca tgaacccaca
     4681 gaggtccaag cgggtaactg atggtgagag atgagtgatc ggtcctacct tcccctttcc
     4741 cttttgtctg atgttgagat ttgaacctga gttgtggagg tcatgcccaa acccctccat
     4801 gttgcttagg gctggaagag ggaccagaaa ccccaggacc tagttccttt tgggaatatt
     4861 ggcattctgg ggtgtgtgtc tttttaagtg tggtcaaaca ctcttgatgt accaaatagt
     4921 gttccccgtg aagcgctctt cctgaggctc ccacccagca acactggtct gagggaagga
     4981 aaggccaaac caggcctggg cacatgaaat tgcacttctt aaagagaaac tttttagaag
     5041 gttgggtatt tttcttaatc acaaaaatct cccactgaaa gaacctaagc tacattcaga
     5101 tcgaagcctc taaattaaat tgtttacttt acaatgttta cacacatgac tcactttttt
     5161 agaaaaataa gaaaactgca aactccggct ttttaacaac ttttcagctt tttcatgcat
     5221 gggatagata tgctggcaac ctgactcacc agctggatca aatcctcatt tagaaatgtc
     5281 ccgatatgtg gatatatgtg tcttcccccc tcccaaccac acagctccct cctgcccaga
     5341 cctctgtctg tttctctggt ggcttttgcc tcctgctttg cagaccgcct gcagccatga
     5401 ttttgttacg gcatccacga gccaaagact gcgccttggg agcaggaaca ataagcaata
     5461 ctacaccact cgctactgtc gggggtcttt ttctctttct tttctttttt agcttcactg
     5521 atggcaacag aggaagaaag gaattgaggt ttaggcaagt tctcttcccc tgtgtgacca
     5581 gattctcggt gacacacagt tgtgcagatc actaggagaa caaggttggg ttttcttttc
     5641 tagtgtgtaa cacaaggatc tgcaggattt tccgtagaca aagaggtctc gtgtattttt
     5701 gtccctatcc aaggttatac aaactaattg tgttgtttta tactgtggcc acaaatatta
     5761 tgcaatgcac catttgtttt tgtttttatt ttattaaagg aaatttaatt ta
//
