LOCUS       NM_001135164            2987 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus prostaglandin D2 receptor-like 1 (Ptgdrl1), mRNA.
ACCESSION   NM_001135164 XM_573732
VERSION     NM_001135164.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2987)
  AUTHORS   Thura,M., Hokamura,K., Yamamoto,S., Maeda,M., Furuta,K., Suzuki,M.,
            Ibaraki,K. and Umemura,K.
  TITLE     GIF-0173 protects against cerebral infarction through DP1 receptor
            activation
  JOURNAL   Exp Neurol 219 (2), 481-491 (2009)
   PUBMED   19576888
REFERENCE   2  (bases 1 to 2987)
  AUTHORS   Prenn,C., Heinemann,A., Schuligoi,R. and Peskar,B.A.
  TITLE     CRTH2 is not involved in the anti-enteropooling effect of PGD2 in
            the small intestine
  JOURNAL   Pharmacology 81 (3), 236-240 (2008)
   PUBMED   18212515
  REMARK    GeneRIF: the inhibitory effect of PGD(2) in the small intestine is
            mediated via activation of the DP1 receptor.
REFERENCE   3  (bases 1 to 2987)
  AUTHORS   Wright,D.H., Nantel,F., Metters,K.M. and Ford-Hutchinson,A.W.
  TITLE     A novel biological role for prostaglandin D2 is suggested by
            distribution studies of the rat DP prostanoid receptor
  JOURNAL   Eur J Pharmacol 377 (1), 101-115 (1999)
   PUBMED   10448933
REFERENCE   4  (bases 1 to 2987)
  AUTHORS   Gerashchenko,D., Beuckmann,C.T., Kanaoka,Y., Eguchi,N.,
            Gordon,W.C., Urade,Y., Bazan,N.G. and Hayaishi,O.
  TITLE     Dominant expression of rat prostanoid DP receptor mRNA in
            leptomeninges, inner segments of photoreceptor cells, iris
            epithelium, and ciliary processes
  JOURNAL   J Neurochem 71 (3), 937-945 (1998)
   PUBMED   9721719
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Sep 14, 2022 this sequence version replaced NM_001135164.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ222068.1, AF120101.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-960               JAXUCZ010000015.1  20560261-20561220   c
            961-2987            JAXUCZ010000015.1  20552125-20554151   c
FEATURES             Location/Qualifiers
     source          1..2987
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..2987
                     /gene="Ptgdrl1"
                     /gene_synonym="Ptgdr; Ptgdrl; RGD1565108"
                     /note="prostaglandin D2 receptor-like 1"
                     /db_xref="GeneID:498475"
                     /db_xref="RGD:1565108"
     exon            1..960
                     /gene="Ptgdrl1"
                     /gene_synonym="Ptgdr; Ptgdrl; RGD1565108"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..1191
                     /gene="Ptgdrl1"
                     /gene_synonym="Ptgdr; Ptgdrl; RGD1565108"
                     /note="PGD receptor; prostanoid DP receptor; PGD2
                     receptor; prostaglandin D receptor"
                     /codon_start=1
                     /product="prostaglandin D2 receptor"
                     /protein_id="NP_001128636.2"
                     /db_xref="GeneID:498475"
                     /db_xref="RGD:1565108"
                     /translation="MNESYRCQAATWVERGSSATMGGVLFSAGLLGNLLALVLLARSG
                     LGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNRSLKELLPASGNQ
                     LCEAFAFLMSFFGLASTLQLLAMALECWLSLGHPFFYQRHITARRGVLVAPVAGAFSL
                     AFCALPFAGFGKFVQYCPGTWCFIQMIHKKRSFSVIGFSVLYSSLMALLVLATVVCNL
                     GAMSNLYAMHRRQRHHPRRCSRDRAQSGSDYRHGSPNPLEELDHFVLLALTTVLFTMC
                     SLPLIYRAYYGAFKLVDRADGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKT
                     FTRPLIYRNWCSHSWQTNMESTL"
     exon            961..2987
                     /gene="Ptgdrl1"
                     /gene_synonym="Ptgdr; Ptgdrl; RGD1565108"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagctttct ctgtttcaca acctctgtgc cctgactgca cccggagcag cctggggctc
       61 cttcacagct gtcctggctg cagccttccc tccaggcaga cgtggcaagg actagctatg
      121 aatgagtcct atcgctgtca ggcagccacc tgggtggaac ggggctcctc agcgacaatg
      181 ggtggtgtgc tcttcagtgc aggactgctg ggcaacctcc tggcgctggt gctgctggcg
      241 cgatccgggc tggggtcctg ccggccaggg ccactgcatc cgccgccctc ggtcttttac
      301 gtgctagtgt gcggcttgac agtcaccgac ttgctgggca agtgtctgat cagcccgatg
      361 gtcctggctg cctacgcgca aaatcggagc ctaaaggaac tgctgcctgc ctcaggcaac
      421 cagttatgtg aagccttcgc cttcctgatg tccttctttg ggttagcctc gaccttacag
      481 ctactggcta tggcactaga gtgctggctg tctctgggac accctttctt ctaccaaagg
      541 cacatcaccg cccgccgggg agtgctggtg gcaccagtcg cgggcgcctt ctctttggct
      601 ttctgtgcgc tcccctttgc tggctttggg aagttcgtcc agtactgtcc gggtacctgg
      661 tgcttcatcc agatgatcca caagaagcgc tcattctcgg taataggctt ctctgtgctc
      721 tactccagcc tcatggcgct gctggtcctc gcaactgtgg tgtgcaacct gggtgccatg
      781 tccaacctct atgccatgca caggcgccag aggcaccatc cccgccgctg ctccagggac
      841 cgcgcccagt caggctcaga ctacaggcat gggtccccga atcctttgga ggagctggac
      901 cactttgttc tgctggctct cacgacagtg ctcttcacca tgtgttccct gcctttaatt
      961 tatcgtgctt actatggagc ctttaaactt gtggacagag ctgacggaga ctcggaagac
     1021 ctccaagcct tgcgttttct gtctgtgatt tccatcgtgg acccctggat cttcatcatt
     1081 ttcaggactt cagtattccg gatgttattt cacaagactt tcacaagacc tctgatctac
     1141 agaaactggt gcagccattc ctggcagact aacatggaat ccactttgtg agggctttgc
     1201 atgttctggc aagctgaaaa tacagcacac attcggacaa agaactgtgg ttgaaaaagc
     1261 cttacaattg aaatccttaa aaaatacctc ccacggggag ctagagagat gcatcggccc
     1321 tgaaagagca tttacttttc ttccagagga ctggagtttg atcccagcac ccatatcagg
     1381 tgcctcacaa ccactgtaac cccagctcca agggatctga caccactggg ctccataaac
     1441 acctgcactc atgtgcatat aaccatactc gagctcgctc tctctctctc tctctttctc
     1501 acacacacac acacacacac acacacagag agagagagag agagagagag agagagagag
     1561 agacttaaaa gtaatttaaa gtaaatttaa agtatctccc agaattaaga catctacttt
     1621 tgaaagtaac caattttaca atacgttgtc actctgtctc cataaaccct tttggtccat
     1681 taaaaaaata tactattaac agccactaaa atttgtatgt tgtaaacagt gttaacagtg
     1741 ttatagcaat gattttaatt gtctcaacat ttgtacctga tagttctaaa tgtttagagc
     1801 agtcttaagt gctatggttt ttattgaaat acagtagaaa caatactgtt tcactgtttg
     1861 tcattttgcg gtgggtgctc ttgaacaagc ctagcaatgg ctcacatgtt tttacagtga
     1921 agcctaactt agtttgtatc atcatagctt cttgctgttg ttcgtttggt ttggtttttt
     1981 tgtttgtttt tgtcaaatga cctaagaata atctgaatta tagatacatt tcagaaaaat
     2041 gagttgggaa actagatcag gtcgagcatt tggagcgagc atttcagagg ctcacagcca
     2101 caggtgaagg ctacaactcc atgtagttaa atgaggcagg atgtgagtag gaccaacaac
     2161 tcaaagtgga aaaaaggaaa ctgatctttt gaagtctggt ctggagacag gggtgtcggg
     2221 tgggggggtg gtcaaaaact ttcatgatga gactaaaatt ttcaattcag gaaaccattt
     2281 tcacgttgat ggattctttg aagaagagga attatgtttc ttgggagaac actggtgtgt
     2341 ggctcaccaa agagctggat tatttaccaa tttcagccgt gtgaactcat agggcattta
     2401 gcacagtgag aggcccactc aggatggaac ctctgtggag ggtcatggca atggtcctca
     2461 cagctgcata gtacagcttc ggtctgctgt tagaggaggg aataaaatgg tacctggggc
     2521 tcctatgagc tctgctagca gaaccagagc acagcgtggc tccaaaggac acggagggcg
     2581 ctgtgattgc tcacttatga gatctcaagg gtcagcagct ctatgtgtgg tccaaggaga
     2641 aagtggagca tgggctgccc ctgcactggg agagaaggtt ctagctagag atcacagcaa
     2701 gagctttcag catttctaaa tcaagaggtg gggataagat agagtttttg agtccctgag
     2761 catcctgtca ctcagatgct gaaccagtct taaggtctgc agccggcaat ctcttccaaa
     2821 gacaggagga gctccctctt ccagttcagc agaaaaccaa tttcctcaac tctgaaacct
     2881 cgagatagta ttaacttaat gtattaatat atgtatgtat gcatgtatgt ataccaaaac
     2941 tgaaaaagcc aaattaggaa taaaggaaag ataacttgag agtacga
//
