LOCUS       NM_001413621            1047 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus pre T-cell antigen receptor alpha (Ptcra), mRNA.
ACCESSION   NM_001413621 XM_003750652
VERSION     NM_001413621.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1047)
  AUTHORS   Mandal,M., Borowski,C., Palomero,T., Ferrando,A.A.,
            Oberdoerffer,P., Meng,F., Ruiz-Vela,A., Ciofani,M.,
            Zuniga-Pflucker,J.C., Screpanti,I., Look,A.T., Korsmeyer,S.J.,
            Rajewsky,K., von Boehmer,H. and Aifantis,I.
  TITLE     The BCL2A1 gene as a pre-T cell receptor-induced regulator of
            thymocyte survival
  JOURNAL   J Exp Med 201 (4), 603-614 (2005)
   PUBMED   15728238
REFERENCE   2  (bases 1 to 1047)
  AUTHORS   Alonso-C,L.M., Munoz,J.J. and Zapata,A.G.
  TITLE     Early T cell development can be traced in rat fetal liver
  JOURNAL   Eur J Immunol 30 (12), 3604-3613 (2000)
   PUBMED   11169403
REFERENCE   3  (bases 1 to 1047)
  AUTHORS   Saint-Ruf,C., Ungewiss,K., Groettrup,M., Bruno,L., Fehling,H.J. and
            von Boehmer,H.
  TITLE     Analysis and expression of a cloned pre-T cell receptor gene
  JOURNAL   Science 266 (5188), 1208-1212 (1994)
   PUBMED   7973703
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Nov 3, 2022 this sequence version replaced XM_003750652.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.36746.1,
                                           SRR26360172.1663619.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680439, SAMN06680440
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               JAXUCZ010000009.1  21716522-21716711
            191-511             JAXUCZ010000009.1  21723659-21723979
            512-559             JAXUCZ010000009.1  21725652-21725699
            560-1047            JAXUCZ010000009.1  21726264-21726751
FEATURES             Location/Qualifiers
     source          1..1047
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q12"
     gene            1..1047
                     /gene="Ptcra"
                     /note="pre T-cell antigen receptor alpha"
                     /db_xref="GeneID:116462"
                     /db_xref="RGD:621388"
     exon            1..190
                     /gene="Ptcra"
                     /inference="alignment:Splign:2.1.0"
     CDS             112..732
                     /gene="Ptcra"
                     /note="pTa; pT-alpha; pT-alpha-TCR"
                     /codon_start=1
                     /product="pre T-cell antigen receptor alpha precursor"
                     /protein_id="NP_001400550.1"
                     /db_xref="GeneID:116462"
                     /db_xref="RGD:621388"
                     /translation="MPRHEWAMARTWLLLFLGLRCQALPSGIAGTPFPSLAPPVTLLV
                     DGRRHTLVVCLVLDAAPPGLDSLVWFSGGNGSALDAFTYGPSPAPDGTWTSLGQLSLS
                     SEELEAWEPLVCHTRPAAGGLNRSTHPLQLSGEEASTDRTCPQETLRGTQRQVLRLSV
                     LRLLLFKLLLLDVFLTCSRLCVLAGQHLLPPPSSKQAPASTHQSWT"
     exon            191..511
                     /gene="Ptcra"
                     /inference="alignment:Splign:2.1.0"
     exon            512..559
                     /gene="Ptcra"
                     /inference="alignment:Splign:2.1.0"
     exon            560..1047
                     /gene="Ptcra"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agactagggg agcctcctcc ctaacccaca cctcagcagc agctgggcct gcggcctgac
       61 aggctagggg agcctcctcc cccagcaggt acctcacgct gcaactgggt catgcctcgt
      121 cacgagtggg ccatggctag gacatggctg ctgcttttcc tgggcctcag gtgtcaggct
      181 ctaccatcag gcatcgctgg cacccccttt ccttctttgg ctccacccgt cacgctgctg
      241 gtggacggaa ggcggcacac gctggtggtc tgcctggtcc tggacgcagc accccctggc
      301 cttgacagcc ttgtctggtt ctcaggtgga aacggcagtg cactagacgc cttcacctac
      361 gggccctctc cggcaccaga tggcacctgg actagcctgg gccagctttc cttgtcctct
      421 gaagagcttg aagcttggga gcccttggtc tgccacacta ggcctgcagc cggaggcctc
      481 aacaggagca cgcaccccct ccagctgtca ggggaagaag cttccacaga cagaacctgc
      541 cctcaggaga ctctcagggg gacacaacgt caggtactgc ggctgagcgt cctgcgtctg
      601 ctcctcttca agctgcttct gctagatgtg ttcctgacct gcagccgcct ctgtgtgctg
      661 gcgggccagc acctattgcc accaccctca agcaagcaag ccccagcttc cacccaccaa
      721 agttggactt aatgaggtta tgagcttgat cttgtccacc catctaagtc tagggtggta
      781 acactggaca ctactgctcc ctggggcagg aaacacagag tcccggagct ggtgatcccc
      841 gctcagtgtt tcttgttcaa actggggact tccttgtttt tgtgtatgtg gtctccctct
      901 tcctgtgatt agagctatcg gggactggag tcttgcctcc cctatcagac tgagactttg
      961 ggaggaaaag gactatgtct ctcccatcag actgggcagg aggatgtgcc cggtaactag
     1021 gcacaatata aaaggtttat acaacac
//
