LOCUS       NM_001106824            1612 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus proline-serine-threonine phosphatase-interacting
            protein 1 (Pstpip1), mRNA.
ACCESSION   NM_001106824 XM_001070448 XM_217152
VERSION     NM_001106824.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1612)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 1612)
  AUTHORS   Yu JW, Fernandes-Alnemri T, Datta P, Wu J, Juliana C, Solorzano L,
            McCormick M, Zhang Z and Alnemri ES.
  TITLE     Pyrin activates the ASC pyroptosome in response to engagement by
            autoinflammatory PSTPIP1 mutants
  JOURNAL   Mol Cell 28 (2), 214-227 (2007)
   PUBMED   17964261
REFERENCE   3  (bases 1 to 1612)
  AUTHORS   Baum W, Kirkin V, Fernandez SB, Pick R, Lettau M, Janssen O and
            Zornig M.
  TITLE     Binding of the intracellular Fas ligand (FasL) domain to the
            adaptor protein PSTPIP results in a cytoplasmic localization of
            FasL
  JOURNAL   J Biol Chem 280 (48), 40012-40024 (2005)
   PUBMED   16204241
  REMARK    GeneRIF: the intracellular Fas ligand (FasL) domain binding to the
            adaptor protein PSTPIP results in a cytoplasmic localization of
            FasL
REFERENCE   4  (bases 1 to 1612)
  AUTHORS   Spencer S, Dowbenko D, Cheng J, Li W, Brush J, Utzig S, Simanis V
            and Lasky LA.
  TITLE     PSTPIP: a tyrosine phosphorylated cleavage furrow-associated
            protein that is a substrate for a PEST tyrosine phosphatase
  JOURNAL   J Cell Biol 138 (4), 845-860 (1997)
   PUBMED   9265651
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158859.1.
            
            On Jan 26, 2008 this sequence version replaced NM_001106824.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158859.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760384, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1612
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..1612
                     /gene="Pstpip1"
                     /note="proline-serine-threonine phosphatase-interacting
                     protein 1"
                     /db_xref="GeneID:300732"
                     /db_xref="RGD:1307557"
     exon            1..178
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..1393
                     /gene="Pstpip1"
                     /codon_start=1
                     /product="proline-serine-threonine phosphatase-interacting
                     protein 1"
                     /protein_id="NP_001100294.2"
                     /db_xref="GeneID:300732"
                     /db_xref="RGD:1307557"
                     /translation="MTAQLQFRDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDVEELLR
                     QRAQAEERYGKELVQIARKAGGQTEMNSLRTSFDSLKQQTENVGSAHIQLALALREEL
                     RSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKTMESKKSYDQKCRDADDAEQAFER
                     VSASGHQKQIEKSQTKAKQCKESATEADRVYRQNIEQLEKARTEWEQEHRTTCEAFQL
                     QEFDRLTILRNALWVHCNQLSMQCVKDDELYEEVRLTLEGCDVEGDINGFIQSKSTGR
                     EPPAPVPYQNYYDREVTPLTGSPIVQTSCGVIKRFSGLLHGSPKTTPSQAPAASTETL
                     APTSEQKELVYASIEVQATQGNLNSAAQDYRALYDYTAQNSDELDISAGDILAVILEG
                     EDGWWTVERNGQRGFVPGSYLEKL"
     exon            179..279
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            280..354
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            355..389
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            390..496
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            497..559
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            560..658
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            659..704
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            705..784
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            785..883
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            884..980
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1071
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1127
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1261
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1548
                     /gene="Pstpip1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcgtttcag acggcgccga ctggaagtgg gagggagagc ttggtctagc cgcgctagaa
       61 ctgggacttg ctcctggctc ctggcccgca ttcagccctg tttgaagcag gagtgctagc
      121 atttgacaca acagacgaga cgatgaccgc ccagctgcag ttccgcgatg ccttctggtg
      181 cagggacttc acggcccaca cagggtatga ggtactcctg cagaggctgc tggacggcag
      241 gaagatgtgc aaggatgtgg aggagctgct cagacagagg gcccaggcgg aggagaggta
      301 cgggaaggag ctggtgcaga ttgcgcgcaa agctggtggc cagacagaga tgaattccct
      361 gaggacctcc tttgactctc tgaagcagca aacagagaat gtgggcagtg cacacatcca
      421 gctggccctg gccctgcgtg aggagctgcg gagcctggag gagttccgag agagacagaa
      481 agaacagcgg aagaagtatg aggccgtcat ggaccgtgtc cagaagagca agctgtcgct
      541 ctacaagaag accatggagt ccaagaagtc atatgaccag aagtgcaggg acgcagatga
      601 cgctgagcag gccttcgagc gagtgagtgc cagtggtcac caaaagcaaa tagaaaagag
      661 ccagaccaaa gccaagcagt gcaaggagtc ggccacagag gcagatcgag tgtacaggca
      721 aaatattgaa caactggaga aagcaaggac cgaatgggaa caggaacacc ggacaacctg
      781 tgaggccttc cagctgcagg agtttgaccg gctaaccatc ctccgcaatg ccctgtgggt
      841 gcactgtaac cagctctcca tgcagtgtgt caaggacgat gagctctatg aggaagtccg
      901 gctgacactt gagggctgtg atgtggaagg tgatatcaat ggcttcatcc agtccaagag
      961 cactggcaga gagcccccag ctcccgtgcc ttatcagaac tactacgacc gggaggtcac
     1021 cccactgact ggcagcccta tcgtccagac ctcctgtggt gtgataaaga ggttctctgg
     1081 gctgctacat ggaagtccca agaccacacc ttctcaagct cctgccgctt ccacagagac
     1141 tctggctccc acctctgagc agaaagaatt ggtctatgca tccatcgaag tgcaggcaac
     1201 ccaggggaac cttaactcag cagcccagga ctaccgggcg ctctatgact acacggcaca
     1261 gaattctgat gagctggaca tttctgcggg agacatcctg gcagtcatcc tggaagggga
     1321 ggatggctgg tggactgtgg aacgaaacgg acaacgtggc tttgtccctg gttcgtactt
     1381 ggagaagctc tgaggaaaga ccagcggtcc ccacatacct ctgcccggct gtgaggtcaa
     1441 ggactgttcc catcaccgcc ccggcctctc ggggtcagaa ccatggctgg ctgcgctggg
     1501 gatgggatgg ttgctggcta ctctcaataa acttctccca ggagtaaaaa aaaaaaaaaa
     1561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
