LOCUS       NM_001399237            1007 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus proteasome assembly chaperone 1 (Psmg1), mRNA.
ACCESSION   NM_001399237 XM_006248154
VERSION     NM_001399237.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1007)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   2  (bases 1 to 1007)
  AUTHORS   Sasaki,K., Hamazaki,J., Koike,M., Hirano,Y., Komatsu,M.,
            Uchiyama,Y., Tanaka,K. and Murata,S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   3  (bases 1 to 1007)
  AUTHORS   Hirano,Y., Hayashi,H., Iemura,S., Hendil,K.B., Niwa,S.,
            Kishimoto,T., Kasahara,M., Natsume,T., Tanaka,K. and Murata,S.
  TITLE     Cooperation of multiple chaperones required for the assembly of
            mammalian 20S proteasomes
  JOURNAL   Mol Cell 24 (6), 977-984 (2006)
   PUBMED   17189198
REFERENCE   4  (bases 1 to 1007)
  AUTHORS   Hirano,Y., Hendil,K.B., Yashiroda,H., Iemura,S., Nagane,R.,
            Hioki,Y., Natsume,T., Tanaka,K. and Murata,S.
  TITLE     A heterodimeric complex that promotes the assembly of mammalian 20S
            proteasomes
  JOURNAL   Nature 437 (7063), 1381-1385 (2005)
   PUBMED   16251969
REFERENCE   5  (bases 1 to 1007)
  AUTHORS   Vesa,J., Brown,Y., Greenfield,D. and Korenberg,J.R.
  TITLE     Molecular and cellular characterization of the Down syndrome
            critical region protein 2
  JOURNAL   Biochem Biophys Res Commun 328 (1), 235-242 (2005)
   PUBMED   15670775
REFERENCE   6  (bases 1 to 1007)
  AUTHORS   Possik,P.A., Sommer,C.A., Issa Hori,J., Machado-Santelli,G.M.,
            Jamur,M.C. and Henrique-Silva,F.
  TITLE     DSCR2, a Down syndrome critical region protein, is localized to the
            endoplasmic reticulum of mammalian cells
  JOURNAL   Eur J Histochem 48 (3), 267-272 (2004)
   PUBMED   15590417
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Jan 5, 2022 this sequence version replaced XM_006248154.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643289.30667.1,
                                           SRR26643429.40825.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760400,
                                           SAMN12840106 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-163               JAXUCZ010000011.1  48754878-48755040   c
            164-270             JAXUCZ010000011.1  48753353-48753459   c
            271-422             JAXUCZ010000011.1  48751873-48752024   c
            423-485             JAXUCZ010000011.1  48751236-48751298   c
            486-684             JAXUCZ010000011.1  48749590-48749788   c
            685-821             JAXUCZ010000011.1  48748053-48748189   c
            822-1007            JAXUCZ010000011.1  48745581-48745766   c
FEATURES             Location/Qualifiers
     source          1..1007
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..1007
                     /gene="Psmg1"
                     /gene_synonym="Dscr2"
                     /note="proteasome assembly chaperone 1"
                     /db_xref="GeneID:288236"
                     /db_xref="RGD:1305454"
     exon            1..163
                     /gene="Psmg1"
                     /gene_synonym="Dscr2"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..896
                     /gene="Psmg1"
                     /gene_synonym="Dscr2"
                     /note="Down syndrome critical region homolog 2; Down
                     syndrome critical region gene 2; proteasome (prosome,
                     macropain) assembly chaperone 1"
                     /codon_start=1
                     /product="proteasome assembly chaperone 1"
                     /protein_id="NP_001386166.1"
                     /db_xref="GeneID:288236"
                     /db_xref="RGD:1305454"
                     /translation="MAATFFGEVVKGPCRAGTEEEEEEEEQSRRDTPEDREVRRKLAR
                     KREVKLLRRQTETCLEAVLLEKHPCSKFILAVGSNATAFLSSFVMNSGVWEEVGCAKL
                     WNEWCRTTDTVHLSPTDVFCVFYQLKSDPSVLLCQCSCYIAEDQQFQWLEKVFGFRPR
                     KNMQVTVLTCRHITEYKTCESTYNLSSPFLRALKTQKFKDTVYCPLLEQPNIVHGLSA
                     AVLSYCQVWKVPAVLYVCYTDVMKLDLVTVEAFKPIFSSRSLKCLVKNIPESTEILKK
                     LMTTNEIQSNIYT"
     exon            164..270
                     /gene="Psmg1"
                     /gene_synonym="Dscr2"
                     /inference="alignment:Splign:2.1.0"
     exon            271..422
                     /gene="Psmg1"
                     /gene_synonym="Dscr2"
                     /inference="alignment:Splign:2.1.0"
     exon            423..485
                     /gene="Psmg1"
                     /gene_synonym="Dscr2"
                     /inference="alignment:Splign:2.1.0"
     exon            486..684
                     /gene="Psmg1"
                     /gene_synonym="Dscr2"
                     /inference="alignment:Splign:2.1.0"
     exon            685..821
                     /gene="Psmg1"
                     /gene_synonym="Dscr2"
                     /inference="alignment:Splign:2.1.0"
     exon            822..1007
                     /gene="Psmg1"
                     /gene_synonym="Dscr2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctggccgc gcggggctga ggtgccatgg ctgctacgtt ctttggtgag gtggtgaagg
       61 ggccatgccg agctgggact gaggaggagg aagaggagga ggagcagagc aggcgggaca
      121 cgccggagga ccgggaggtc cggcggaagc ttgcgcggaa gagggaggtg aagcttctcc
      181 gaagacagac agaaacatgt ctggaggctg tgctcctaga gaagcaccct tgctccaagt
      241 tcatccttgc agtaggaagt aacgccacgg cgttcctttc atcgtttgtt atgaactcag
      301 gagtctggga agaagtcggt tgtgctaagc tctggaatga atggtgcaga actacagaca
      361 ctgtccacct gtcccctaca gatgttttct gtgtgtttta tcaactgaaa tcagatccct
      421 cggttcttct ctgccagtgt agctgctaca ttgctgagga tcagcagttc cagtggttgg
      481 agaaggtttt cggcttccga cccagaaaga acatgcaggt aacagttctc acgtgtcgac
      541 acatcacaga gtataagacc tgcgagtcta cctacaacct ttcttctcct ttcctgagag
      601 ccctaaaaac tcagaaattc aaagataccg tctactgccc actgctggaa cagccgaaca
      661 ttgtgcacgg cctgtctgca gcagttctga gctactgtca agtgtggaaa gtccctgcgg
      721 ttctgtatgt gtgctacacg gatgtgatga agttggacct tgtcacagtc gaagctttta
      781 agcccatctt ttcgtccagg agcttgaaat gcttggtgaa gaacatccct gaaagcacag
      841 aaatactgaa gaagctgatg actacaaatg agattcagag caacatttac acatgacccc
      901 acagatgtag ccatgacctg cctgtccagg ggcagccact gctgttttgt actttattct
      961 ggcctgggat gttttgaggg taataaaaaa tttaaaatta actgtaa
//
