LOCUS       NM_001100831            1537 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus proteasome 26S subunit, non-ATPase 8 (Psmd8),
            mRNA.
ACCESSION   NM_001100831 XM_001075072 XM_214888
VERSION     NM_001100831.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1537)
  AUTHORS   Hasson,S.A., Kane,L.A., Yamano,K., Huang,C.H., Sliter,D.A.,
            Buehler,E., Wang,C., Heman-Ackah,S.M., Hessa,T., Guha,R.,
            Martin,S.E. and Youle,R.J.
  TITLE     High-content genome-wide RNAi screens identify regulators of parkin
            upstream of mitophagy
  JOURNAL   Nature 504 (7479), 291-295 (2013)
   PUBMED   24270810
REFERENCE   2  (bases 1 to 1537)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 1537)
  AUTHORS   Wang,X., Chen,C.F., Baker,P.R., Chen,P.L., Kaiser,P. and Huang,L.
  TITLE     Mass spectrometric characterization of the affinity-purified human
            26S proteasome complex
  JOURNAL   Biochemistry 46 (11), 3553-3565 (2007)
   PUBMED   17323924
REFERENCE   4  (bases 1 to 1537)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CD371338.1, BC105894.1 and CK844749.1.
            
            On or before Nov 23, 2008 this sequence version replaced
            XM_214888.4, XM_001075072.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ223219.1, FQ233693.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-647               CD371338.1         11-657
            648-1454            BC105894.1         413-1219
            1455-1537           CK844749.1         1-83                c
FEATURES             Location/Qualifiers
     source          1..1537
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..1537
                     /gene="Psmd8"
                     /note="proteasome 26S subunit, non-ATPase 8"
                     /db_xref="GeneID:292766"
                     /db_xref="RGD:1309842"
     exon            1..400
                     /gene="Psmd8"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..1093
                     /gene="Psmd8"
                     /note="proteasome (prosome, macropain) 26S subunit,
                     non-ATPase, 8"
                     /codon_start=1
                     /product="26S proteasome non-ATPase regulatory subunit 8"
                     /protein_id="NP_001094301.1"
                     /db_xref="GeneID:292766"
                     /db_xref="RGD:1309842"
                     /translation="MFIKGRTAKAPRGEPRRSSRRGQKLAVVAPPPALGSTSRPHFRR
                     ESIARRRCRKSGRLFAASRKMAAAAATVNGTTGVSSSGPAATSGGILQAAAGMYEQLK
                     DEWNRKSPNLSKCGEELGRLKLVLLELNFLPTTGTKLTKQQLILARDILEIGAQWSIL
                     CKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERL
                     PAKDIQTNVYIKHPVSLEQYLMEGSYNKVFLAKGNIPAESYTFFIDILLDTIRDEIAG
                     CIEKAYEKILFAEATRILFFSTPKKMTDYAKKRGWLLGPNNYYSFASQQQKPEDSTIP
                     STELARQVIEYARQLEMIV"
     exon            401..473
                     /gene="Psmd8"
                     /inference="alignment:Splign:2.1.0"
     exon            474..576
                     /gene="Psmd8"
                     /inference="alignment:Splign:2.1.0"
     exon            577..742
                     /gene="Psmd8"
                     /inference="alignment:Splign:2.1.0"
     exon            743..843
                     /gene="Psmd8"
                     /inference="alignment:Splign:2.1.0"
     exon            844..955
                     /gene="Psmd8"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1520
                     /gene="Psmd8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttttgaatga caacagaggc ggagctgtgg catgttcatt aagggccgga ctgcgaaggc
       61 gcccagagga gagccgcggc gctcctcccg ccgtgggcag aagctagcag tcgtagctcc
      121 gcctccggct ttgggctcca cctcccggcc tcacttccgc cgggagagca ttgctcggcg
      181 tcgttgccgt aaatcaggtc ggctgtttgc tgcatcacga aagatggcgg ccgcggcggc
      241 tacggtgaac gggacaaccg gcgtttcaag ctccgggccc gcggccacct cgggcgggat
      301 cctacaggca gcggccggca tgtacgagca actcaaagac gagtggaacc ggaagagccc
      361 gaatcttagt aaatgtggag aagagctggg ccgcctgaag ttggttctgc tggagctcaa
      421 tttcctgcca accacgggga ccaaactgac taaacagcag ctcattctgg cccgtgacat
      481 tctggaaatc ggggcccagt ggagcatcct atgcaaggac attccctcct tcgagcgcta
      541 catggcccag ctcaaatgct actactttga ttacaaggag cagcttcctg agtcagccta
      601 catgcaccag ctcctgggcc tcaacctcct cttcctgctc tctcagaacc gagtggctga
      661 gttccacaca gaattagaac gattgcctgc caaggacatc caaaccaatg tctacatcaa
      721 acaccctgta tccctcgagc aatacctcat ggagggtagc tacaacaagg tgttcctggc
      781 taagggaaac attcccgctg agagctatac cttcttcatt gacatcctgc tggatactat
      841 cagggatgaa attgcaggat gcattgagaa ggcctatgag aaaatccttt ttgctgaggc
      901 tacccggatc ctcttcttca gcacacccaa aaagatgaca gactatgcca agaagcgagg
      961 ttggctgctg ggccctaaca actactacag ctttgccagc cagcagcaga agccagaaga
     1021 cagcaccatc ccctccactg agctggccag gcaggtcatc gagtatgccc ggcagctgga
     1081 gatgattgtc tgagcctcgg ccaaggtggt gggcatggct ggtccagcag tcttagcacg
     1141 ggctggccct caataaaggc agattaacct cctatgggcc ctagtctccc cagtgggatg
     1201 gtggagataa gaatttggga gtttgggggc ctctgggcct tctgggtgag tgtttcctcc
     1261 cagttgtcac tgctctgggt tttcagcata gctgcccagt ggcccgcagg agagcacagg
     1321 ccctgactga ggtgctcttc tagccagctg tgggtgcctt ttggtactgg gcaaggggat
     1381 tgttttccag tgaagcacca tgtgtctcag tttttaaaaa atgttggcca tggattaaat
     1441 aatttttaaa atgacacatg aaactgactt tgtctgtggg ctaccatttg agcctctgta
     1501 ataaatggta tggaccctga aaaaaaaaaa aaaaaaa
//
