LOCUS       NM_001107426            1588 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus proteasome 26S subunit, non-ATPase 7 (Psmd7),
            mRNA.
ACCESSION   NM_001107426 XM_001076658 XM_226439
VERSION     NM_001107426.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1588)
  AUTHORS   Droggiti A, Ho CC, Stefanis L, Dauer WT and Rideout HJ.
  TITLE     Targeted disruption of neuronal 19S proteasome subunits induces the
            formation of ubiquitinated inclusions in the absence of cell death
  JOURNAL   J Neurochem 119 (3), 630-643 (2011)
   PUBMED   21883213
  REMARK    GeneRIF: Subunits of the 19S regulatory proteasome induced
            inclusion formation but was unable to induce apoptotic death, or
            trigger activation of macroautophagy.
REFERENCE   2  (bases 1 to 1588)
  AUTHORS   de Mateo S, Castillo J, Estanyol JM, Ballesca JL and Oliva R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 1588)
  AUTHORS   Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M and
            Stoorvogel W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 1588)
  AUTHORS   Sasaki K, Hamazaki J, Koike M, Hirano Y, Komatsu M, Uchiyama Y,
            Tanaka K and Murata S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   5  (bases 1 to 1588)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 1588)
  AUTHORS   Sanches M, Alves BS, Zanchin NI and Guimaraes BG.
  TITLE     The crystal structure of the human Mov34 MPN domain reveals a
            metal-free dimer
  JOURNAL   J Mol Biol 370 (5), 846-855 (2007)
   PUBMED   17559875
REFERENCE   7  (bases 1 to 1588)
  AUTHORS   Wang X, Chen CF, Baker PR, Chen PL, Kaiser P and Huang L.
  TITLE     Mass spectrometric characterization of the affinity-purified human
            26S proteasome complex
  JOURNAL   Biochemistry 46 (11), 3553-3565 (2007)
   PUBMED   17323924
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473972.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001076658.1, XM_226439.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EV777702.1, EV762124.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1588
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..1588
                     /gene="Psmd7"
                     /note="proteasome 26S subunit, non-ATPase 7"
                     /db_xref="GeneID:307821"
                     /db_xref="RGD:1306902"
     exon            1..204
                     /gene="Psmd7"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..1093
                     /gene="Psmd7"
                     /note="proteasome (prosome, macropain) 26S subunit,
                     non-ATPase, 7"
                     /codon_start=1
                     /product="26S proteasome non-ATPase regulatory subunit 7"
                     /protein_id="NP_001100896.1"
                     /db_xref="GeneID:307821"
                     /db_xref="RGD:1306902"
                     /translation="MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQ
                     KKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLH
                     KNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTS
                     EIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRTYLEKVASG
                     KLPINHHIIYQLQDVFNLLPDASLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLI
                     NNKIANRDAEKKEGQEKEESKKERKDDKEKEKSDAKKEEKKEKK"
     exon            205..296
                     /gene="Psmd7"
                     /inference="alignment:Splign:2.1.0"
     exon            297..389
                     /gene="Psmd7"
                     /inference="alignment:Splign:2.1.0"
     exon            390..487
                     /gene="Psmd7"
                     /inference="alignment:Splign:2.1.0"
     exon            488..568
                     /gene="Psmd7"
                     /inference="alignment:Splign:2.1.0"
     exon            569..660
                     /gene="Psmd7"
                     /inference="alignment:Splign:2.1.0"
     exon            661..1588
                     /gene="Psmd7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagtcgact gtgcggtggc ggtcaaaccg gaaggggagg tgctggggcc tggaggagcg
       61 gcctgtaacg ctgcggttgc cggtgtttgc gggttgcagg gagccgggcc ggcggtcggg
      121 ctgtgtcgcg atgccggagc tggcggtgca gaaagtggtg gtccaccccc tggtgctgct
      181 cagtgtggtg gatcatttca accgaatcgg caaggttgga aaccagaagc gggttgttgg
      241 tgtgcttttg ggatcatggc aaaagaaagt ccttgatgta tccaacagct ttgcagtacc
      301 ttttgatgaa gatgacaaag atgattctgt ctggttttta gaccatgatt atttggaaaa
      361 catgtatggg atgtttaaga aggtcaatgc cagagaaaga atagttgggt ggtaccacac
      421 aggccccaaa ctgcacaaga acgatatcgc catcaatgaa ctcatgaaga gatactgccc
      481 caactcggta ctggtcatta ttgatgtgaa gccaaaagac ttggggcttc cgaccgaagc
      541 ctacatctca gtggaggaag ttcatgatga cggaacacca acatcaaaaa cttttgagca
      601 cgtgactagt gaaattggag cagaggaggc tgaggaggtt ggagtggagc acttgttacg
      661 ggacatcaag gacactacag tggggactct gtctcagagg atcactaacc aggtccatgg
      721 tttgaaggga ctgaactcca agctcctgga tatcaggacc tacctggaga aggtagccag
      781 cggcaagcta cccatcaacc accacatcat ataccagctg caggacgtct tcaacctgct
      841 gccggacgcc agcctgcagg agttcgtcaa ggccttctac ctgaagacca atgaccagat
      901 ggttgtggtg tacctggcct cgctgatccg ctctgtggtc gccttgcata acctcatcaa
      961 caacaagatt gccaaccgcg atgcggagaa gaaagaggga caggagaagg aggagagcaa
     1021 gaaggagaga aaagacgaca aggagaagga gaagagcgat gcgaagaaag aggagaaaaa
     1081 ggagaaaaag taaatcgtgt agctttttta atttgtaaat taaaatctta taaacttaac
     1141 tccgtgtgcc actagagggt cctttgtcac attcagtgct tgttgacaag cgctctctgc
     1201 cctggtcacc cttgctgtgg cattttgtgg agatgaatgg acagaaggac cgagctcagc
     1261 cctatgccac agcgtccgtt gcatgagttg ggggtgcggt ggctcgggtg tcccattgtg
     1321 agaacaacgt aatctgtggc actctccttt tatccttaaa aggaattttt tcctgtctta
     1381 taagattcag gggtctgttg gtggtaattt tcataattgc taaatggaat tcatggaccc
     1441 cacactctgc cacccaacac ttgagctccg acccccctga acaccagacc acagcacatt
     1501 ttggacctgt aactcgcatt cttagggctt ggggtccaag gccatgtatt gtttaccttc
     1561 aaagatacaa ttaaatggct tggttttt
//
