LOCUS       NM_053925               1433 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus proteasome 26S subunit, non-ATPase 10 (Psmd10),
            transcript variant 1, mRNA.
ACCESSION   NM_053925
VERSION     NM_053925.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1433)
  AUTHORS   Kaneko,T., Hamazaki,J., Iemura,S., Sasaki,K., Furuyama,K.,
            Natsume,T., Tanaka,K. and Murata,S.
  TITLE     Assembly pathway of the Mammalian proteasome base subcomplex is
            mediated by multiple specific chaperones
  JOURNAL   Cell 137 (5), 914-925 (2009)
   PUBMED   19490896
REFERENCE   2  (bases 1 to 1433)
  AUTHORS   Wang,J., Wang,X.F., Zhang,L.G., Xie,S.Y., Li,Z.L., Li,Y.J., Li,H.H.
            and Jiao,F.
  TITLE     Involvement of the mitochondrial pathway in p53-independent
            apoptosis induced by p28GANK knockdown in Hep3B cells
  JOURNAL   Cytogenet Genome Res 125 (2), 87-97 (2009)
   PUBMED   19729910
  REMARK    Erratum:[Cytogenet Genome Res. 2009;127(1):25]
REFERENCE   3  (bases 1 to 1433)
  AUTHORS   Chen,Y., Li,H.H., Fu,J., Wang,X.F., Ren,Y.B., Dong,L.W., Tang,S.H.,
            Liu,S.Q., Wu,M.C. and Wang,H.Y.
  TITLE     Oncoprotein p28 GANK binds to RelA and retains NF-kappaB in the
            cytoplasm through nuclear export
  JOURNAL   Cell Res 17 (12), 1020-1029 (2007)
   PUBMED   18040287
REFERENCE   4  (bases 1 to 1433)
  AUTHORS   Wang,X., Chen,C.F., Baker,P.R., Chen,P.L., Kaiser,P. and Huang,L.
  TITLE     Mass spectrometric characterization of the affinity-purified human
            26S proteasome complex
  JOURNAL   Biochemistry 46 (11), 3553-3565 (2007)
   PUBMED   17323924
REFERENCE   5  (bases 1 to 1433)
  AUTHORS   Higashitsuji,H., Higashitsuji,H., Itoh,K., Sakurai,T., Nagao,T.,
            Sumitomo,Y., Masuda,T., Dawson,S., Shimada,Y., Mayer,R.J. and
            Fujita,J.
  TITLE     The oncoprotein gankyrin binds to MDM2/HDM2, enhancing
            ubiquitylation and degradation of p53
  JOURNAL   Cancer Cell 8 (1), 75-87 (2005)
   PUBMED   16023600
  REMARK    Erratum:[Cancer Cell. 2005 Aug;8(2):169. Sumitomo, Haruhiko
            [corrected to Sumitomo, Yasuhiko]]
REFERENCE   6  (bases 1 to 1433)
  AUTHORS   Rezvani,K., Mee,M., Dawson,S., McIlhinney,J., Fujita,J. and
            Mayer,R.J.
  TITLE     Proteasomal interactors control activities as diverse as the cell
            cycle and glutaminergic neurotransmission
  JOURNAL   Biochem Soc Trans 31 (2), 470-473 (2003)
   PUBMED   12653665
REFERENCE   7  (bases 1 to 1433)
  AUTHORS   Li,J. and Tsai,M.D.
  TITLE     Novel insights into the INK4-CDK4/6-Rb pathway: counter action of
            gankyrin against INK4 proteins regulates the CDK4-mediated
            phosphorylation of Rb
  JOURNAL   Biochemistry 41 (12), 3977-3983 (2002)
   PUBMED   11900540
REFERENCE   8  (bases 1 to 1433)
  AUTHORS   Higashitsuji,H., Itoh,K., Nagao,T., Dawson,S., Nonoguchi,K.,
            Kido,T., Mayer,R.J., Arii,S. and Fujita,J.
  TITLE     Reduced stability of retinoblastoma protein by gankyrin, an
            oncogenic ankyrin-repeat protein overexpressed in hepatomas
  JOURNAL   Nat Med 6 (1), 96-99 (2000)
   PUBMED   10613832
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Sep 1, 2022 this sequence version replaced NM_053925.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.1459125.1,
                                           SRR26360194.1832327.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676811 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-156               JAXUCZ010000021.1  109453450-109453605 c
            157-255             JAXUCZ010000021.1  109450613-109450711 c
            256-402             JAXUCZ010000021.1  109449223-109449369 c
            403-569             JAXUCZ010000021.1  109448967-109449133 c
            570-1433            JAXUCZ010000021.1  109445291-109446154 c
FEATURES             Location/Qualifiers
     source          1..1433
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq33"
     gene            1..1433
                     /gene="Psmd10"
                     /gene_synonym="p28Gank"
                     /note="proteasome 26S subunit, non-ATPase 10"
                     /db_xref="GeneID:116722"
                     /db_xref="RGD:620350"
     exon            1..156
                     /gene="Psmd10"
                     /gene_synonym="p28Gank"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..738
                     /gene="Psmd10"
                     /gene_synonym="p28Gank"
                     /note="isoform 1 is encoded by transcript variant 1; 26S
                     proteasome non-ATPase regulatory subunit 10; 26S
                     proteasome regulatory subunit p28; gankyrin; proteasome
                     (prosome, macropain) 26S subunit, non-ATPase, 10"
                     /codon_start=1
                     /product="26S proteasome non-ATPase regulatory subunit 10
                     isoform 1"
                     /protein_id="NP_446377.2"
                     /db_xref="GeneID:116722"
                     /db_xref="RGD:620350"
                     /translation="MEGCVSNVMICNLAYNGKLDELKESILADKSLATRTDQDSRTAL
                     HWACSAGHTEIVEFLLQLGVPVNEKDDAGWSPLHIAASAGRDEIVKALLIKGAQVNAV
                     NQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLF
                     YKASTNIQDTEGNTPLHLACDEERVEEAKLLVTQGASIYIENKEEKTPLQVAKGGLGL
                     ILKRIVESEAASM"
     exon            157..255
                     /gene="Psmd10"
                     /gene_synonym="p28Gank"
                     /inference="alignment:Splign:2.1.0"
     exon            256..402
                     /gene="Psmd10"
                     /gene_synonym="p28Gank"
                     /inference="alignment:Splign:2.1.0"
     exon            403..569
                     /gene="Psmd10"
                     /gene_synonym="p28Gank"
                     /inference="alignment:Splign:2.1.0"
     exon            570..1433
                     /gene="Psmd10"
                     /gene_synonym="p28Gank"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgggcgggg cttgagtttc acggaggtcc tgggaaggcg aaatggaggg gtgtgtgtct
       61 aacgtcatga tctgtaacct ggcctacaac gggaagctgg atgagttgaa ggaaagcatt
      121 ttggctgata agtctctggc cactagaact gatcaggaca gcagaacagc attgcactgg
      181 gcatgctcag ctggtcatac agaaattgtt gaattcttgc tgcaacttgg agtgccagtg
      241 aatgaaaaag acgatgcagg ttggtctcct cttcatattg ctgcttccgc tggccgggat
      301 gagattgtaa aagcccttct gataaaaggg gcacaagtga atgccgtcaa tcaaaatggc
      361 tgcacgcccc tccattatgc agcttccaag aataggcatg agattgctgt tatgttacta
      421 gaaggtgggg ctaatccaga tgctaaggac cattatgatg ctacagcaat gcaccgggca
      481 gcagccaagg gtaacttgaa gatggttcat atccttctgt tctacaaagc atccacaaac
      541 atccaagata ctgagggtaa cactcctcta cacttagcct gtgatgagga gagagtggaa
      601 gaagcaaaat tgctggtgac ccaaggagca agtatttaca ttgaaaataa ggaagaaaag
      661 acaccgctgc aagtcgccaa aggaggcctg ggtttaatac tcaaaagaat cgtagaaagt
      721 gaagcagctt ctatgtagtc tgtgtatgta tgtcctcact gtcctggaaa ctgttgtact
      781 gctcacaagg catctcgtat gaaaatgttt tctcgtcttc ataatttgat aacgtgttgt
      841 attgctccta tcgaagtact tgttctacac ttactaccca ctttccaggc attgaaaaac
      901 tggtgagctt gttctactga tgtcattcat taaatcttga ttactttgga gtaagtggtt
      961 gtggctgtcc tgtcttgagc atcctccatg cacttactga cccgctgtgc aacagaacat
     1021 gttcagaaat ggcctgccag ttgggccagg tggttctggg agcttctgtg atctctgcag
     1081 tcaaaacaaa tactgacctg tttttcaagt tcactcagag acctatgcca aatatttcca
     1141 tttttttcaa ctacaaggtt aatttatttt tgttacagga ggaagttcta tattttagag
     1201 gagcaaattt taagtcaaat tgtatgttct taaaataatg aagaacgaga gcctacgtgc
     1261 ccatgtacca ttgtaactag ccatttccct ctaaaataag acatatcatt ttaaaaaaaa
     1321 taaattaact caccttgtat tgaaaagaat tgtcaaactt attaaaaaca tgtataacaa
     1381 aattaatttt gatttgtatt tcaagtatta caaacaataa actgttgaaa gaa
//
