LOCUS       NM_134458                936 bp    mRNA    linear   ROD 04-DEC-2024
DEFINITION  Rattus norvegicus PSMC3 interacting protein (Psmc3ip), mRNA.
ACCESSION   NM_134458
VERSION     NM_134458.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 936)
  AUTHORS   Zangen,D., Kaufman,Y., Zeligson,S., Perlberg,S., Fridman,H.,
            Kanaan,M., Abdulhadi-Atwan,M., Abu Libdeh,A., Gussow,A.,
            Kisslov,I., Carmel,L., Renbaum,P. and Levy-Lahad,E.
  TITLE     XX ovarian dysgenesis is caused by a PSMC3IP/HOP2 mutation that
            abolishes coactivation of estrogen-driven transcription
  JOURNAL   Am J Hum Genet 89 (4), 572-579 (2011)
   PUBMED   21963259
REFERENCE   2  (bases 1 to 936)
  AUTHORS   Ko,L., Cardona,G.R., Henrion-Caude,A. and Chin,W.W.
  TITLE     Identification and characterization of a tissue-specific
            coactivator, GT198, that interacts with the DNA-binding domains of
            nuclear receptors
  JOURNAL   Mol Cell Biol 22 (1), 357-369 (2002)
   PUBMED   11739747
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF352812.1 and CK840952.1.
            
            On Oct 13, 2005 this sequence version replaced NM_134458.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF352812.1, SRR8487227.291632.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-456               AF352812.1         1-456
            457-936             CK840952.1         1-480               c
FEATURES             Location/Qualifiers
     source          1..936
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..936
                     /gene="Psmc3ip"
                     /gene_synonym="Gt198; Tbpip"
                     /note="PSMC3 interacting protein"
                     /db_xref="GeneID:140938"
                     /db_xref="RGD:621885"
     exon            1..56
                     /gene="Psmc3ip"
                     /gene_synonym="Gt198; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..676
                     /gene="Psmc3ip"
                     /gene_synonym="Gt198; Tbpip"
                     /note="proteasome 26S ATPase subunit 3-interacting
                     protein; proteasome (prosome, macropain) 26S subunit,
                     ATPase 3, interacting protein; nuclear receptor
                     coactivator GT198"
                     /codon_start=1
                     /product="homologous-pairing protein 2 homolog"
                     /protein_id="NP_604453.2"
                     /db_xref="GeneID:140938"
                     /db_xref="RGD:621885"
                     /translation="MSKSRAEAAAGAPGIVLRYLQEQNRPYSAQDVFGNLQKEHGLGK
                     AAVVKALDQLAQQGKIKEKTYGKQKIYFADQDQFDTVSDADLHSLDASIMALTAKVQG
                     LQQSCRHMEAELKELTSALTTPEMQTEIQELKKECARYTERLKNIKAATNHVTPEEKE
                     KVYRERQKYCKEWRKRKRMTTELCDAILEGYPKSKKQFFEEVGIETDEDHNVTLPDP"
     exon            57..157
                     /gene="Psmc3ip"
                     /gene_synonym="Gt198; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            158..247
                     /gene="Psmc3ip"
                     /gene_synonym="Gt198; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            248..359
                     /gene="Psmc3ip"
                     /gene_synonym="Gt198; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            360..505
                     /gene="Psmc3ip"
                     /gene_synonym="Gt198; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            506..559
                     /gene="Psmc3ip"
                     /gene_synonym="Gt198; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            560..619
                     /gene="Psmc3ip"
                     /gene_synonym="Gt198; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            620..919
                     /gene="Psmc3ip"
                     /gene_synonym="Gt198; Tbpip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagtttggtg gcgggaaagg ccatgagtaa aagccgggcc gaagctgcgg ctggagcccc
       61 cgggatcgtc ctaaggtacc tgcaggaaca aaaccggccc tacagcgccc aggacgtgtt
      121 cgggaacctg cagaaggaac atggactggg caaggcggcg gtggtgaagg cactcgatca
      181 gctggcccag caaggcaaga tcaaagagaa gacttacggc aagcagaaga tatattttgc
      241 cgatcaggac cagtttgaca cagtgagtga tgcggacctc cacagtctgg atgccagtat
      301 catggccctc actgccaagg tgcagggctt acagcagagc tgccggcaca tggaggctga
      361 gctgaaggaa ttaacaagtg cgctgaccac tcctgagatg cagacagaga ttcaggagtt
      421 gaagaaggag tgtgctcgct acacagagag actgaaaaac atcaaagcag ctaccaacca
      481 tgtcactcca gaagagaagg agaaggtgta cagggagaga cagaagtact gtaaagagtg
      541 gaggaagcgg aagagaatga ccacagagct gtgcgatgcg atccttgaag gttaccccaa
      601 gagcaagaag cagttctttg aagaagttgg gatagagaca gatgaagatc ataatgttac
      661 gctcccagac ccctgagggg cccttgatgg aggtgggaac agaccgtcct gctttggcca
      721 ccttactgag gtggcctttt tattcttgct gttctccacc tttgagcagt ggacagagga
      781 gcacagaggc atagtgttag gtagaggctg ctggttagaa agggatggtc acaatcattt
      841 tgcacaggcc tcaacaagga cttgtaacaa tcctaaagta tttgtaatat ttattgtaat
      901 ataatttgat ataaaaataa aaaaaaaaaa aaaaaa
//
