LOCUS       NM_031595               1626 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus proteasome 26S subunit, ATPase 3 (Psmc3), mRNA.
ACCESSION   NM_031595
VERSION     NM_031595.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1626)
  AUTHORS   Topalidou,I., Cattin-Ortola,J., Pappas,A.L., Cooper,K.,
            Merrihew,G.E., MacCoss,M.J. and Ailion,M.
  TITLE     The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo
            Sorting to Dense-Core Vesicles
  JOURNAL   PLoS Genet 12 (5), e1006074 (2016)
   PUBMED   27191843
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1626)
  AUTHORS   Lukic,Z., Hausmann,S., Sebastian,S., Rucci,J., Sastri,J.,
            Robia,S.L., Luban,J. and Campbell,E.M.
  TITLE     TRIM5alpha associates with proteasomal subunits in cells while in
            complex with HIV-1 virions
  JOURNAL   Retrovirology 8, 93 (2011)
   PUBMED   22078707
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1626)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   4  (bases 1 to 1626)
  AUTHORS   Truax,A.D., Koues,O.I., Mentel,M.K. and Greer,S.F.
  TITLE     The 19S ATPase S6a (S6'/TBP1) regulates the transcription
            initiation of class II transactivator
  JOURNAL   J Mol Biol 395 (2), 254-269 (2010)
   PUBMED   19853614
REFERENCE   5  (bases 1 to 1626)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 1626)
  AUTHORS   Sakao,Y., Kawai,T., Takeuchi,O., Copeland,N.G., Gilbert,D.J.,
            Jenkins,N.A., Takeda,K. and Akira,S.
  TITLE     Mouse proteasomal ATPases Psmc3 and Psmc4: genomic organization and
            gene targeting
  JOURNAL   Genomics 67 (1), 1-7 (2000)
   PUBMED   10945464
REFERENCE   7  (bases 1 to 1626)
  AUTHORS   Rivkin,E., Cullinan,E.B., Tres,L.L. and Kierszenbaum,A.L.
  TITLE     A protein associated with the manchette during rat spermiogenesis
            is encoded by a gene of the TBP-1-like subfamily with highly
            conserved ATPase and protease domains
  JOURNAL   Mol Reprod Dev 48 (1), 77-89 (1997)
   PUBMED   9266764
REFERENCE   8  (bases 1 to 1626)
  AUTHORS   Makino,Y., Yogosawa,S., Kanemaki,M., Yoshida,T., Yamano,K.,
            Kishimoto,T., Moncollin,V., Egly,J.M., Muramatsu,M. and Tamura,T.
  TITLE     Structures of the rat proteasomal ATPases: determination of highly
            conserved structural motifs and rules for their spacing
  JOURNAL   Biochem Biophys Res Commun 220 (3), 1049-1054 (1996)
   PUBMED   8607789
REFERENCE   9  (bases 1 to 1626)
  AUTHORS   Ohana,B., Moore,P.A., Ruben,S.M., Southgate,C.D., Green,M.R. and
            Rosen,C.A.
  TITLE     The type 1 human immunodeficiency virus Tat binding protein is a
            transcriptional activator belonging to an additional family of
            evolutionarily conserved genes
  JOURNAL   Proc Natl Acad Sci U S A 90 (1), 138-142 (1993)
   PUBMED   8419915
REFERENCE   10 (bases 1 to 1626)
  AUTHORS   Nelbock,P., Dillon,P.J., Perkins,A. and Rosen,C.A.
  TITLE     A cDNA for a protein that interacts with the human immunodeficiency
            virus Tat transactivator
  JOURNAL   Science 248 (4963), 1650-1653 (1990)
   PUBMED   2194290
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Nov 26, 2020 this sequence version replaced NM_031595.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U77918.1, BC062019.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-312               JAXUCZ010000003.1  97487643-97487954
            313-396             JAXUCZ010000003.1  97488211-97488294
            397-522             JAXUCZ010000003.1  97488596-97488721
            523-627             JAXUCZ010000003.1  97489127-97489231
            628-690             JAXUCZ010000003.1  97489316-97489378
            691-828             JAXUCZ010000003.1  97489599-97489736
            829-972             JAXUCZ010000003.1  97490414-97490557
            973-1121            JAXUCZ010000003.1  97490664-97490812
            1122-1218           JAXUCZ010000003.1  97491518-97491614
            1219-1364           JAXUCZ010000003.1  97491761-97491906
            1365-1446           JAXUCZ010000003.1  97492658-97492739
            1447-1626           JAXUCZ010000003.1  97492845-97493024
FEATURES             Location/Qualifiers
     source          1..1626
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q24"
     gene            1..1626
                     /gene="Psmc3"
                     /note="proteasome 26S subunit, ATPase 3"
                     /db_xref="GeneID:29677"
                     /db_xref="RGD:61905"
     exon            1..312
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             229..1557
                     /gene="Psmc3"
                     /note="26S protease regulatory subunit 6A; TBP-1;
                     TAT-binding protein 1; spermatogenic cell/sperm-associated
                     TAT-binding protein homolog SATA; 26S proteasome
                     AAA-ATPase subunit RPT5; proteasome (prosome, macropain)
                     26S subunit, ATPase 3"
                     /codon_start=1
                     /product="26S proteasome regulatory subunit 6A"
                     /protein_id="NP_113783.2"
                     /db_xref="GeneID:29677"
                     /db_xref="RGD:61905"
                     /translation="MQEMNLLPTPESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEI
                     VQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDV
                     DPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDS
                     YLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENL
                     GIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFA
                     LAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAA
                     TNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTD
                     DFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA"
     exon            313..396
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     exon            397..522
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     exon            523..627
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     exon            628..690
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     exon            691..828
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     exon            829..972
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1121
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1218
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1364
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1365..1446
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1447..1626
                     /gene="Psmc3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 catttctccc tcacaaactg gagcaaccgg cgagcccggg gcgggccctg tggcctcggt
       61 ttggttcgtg gagtcccagc ggcagattcg ctcggcaacg cggacagggc caattctgtc
      121 gcgtcaggaa tcgcgggtga agttcgccac gggtggagag aagacgttga ggaaagccgc
      181 gctgggctcc ctcaggggct cgtgcgcact cccagtttcg gccttttcat gcaggaaatg
      241 aatctgctgc cgacgcccga gagtccagtg actcggcagg agaagatggc gaccgtgtgg
      301 gatgaagctg agcaagatgg cattggggag gaggtgctca agatgtccac agaagagatc
      361 gtccagcgca cacggctgct agacagcgag atcaagatca tgaagagtga agtgctgcga
      421 gtcacccacg aactccaagc catgaaagac aaaatcaaag agaacagtga gaaaatcaaa
      481 gtgaacaaaa ccctcccata cctagtctcc aacgttattg agttgctgga tgttgacccc
      541 aatgaccagg aggaggatgg tgccaatatt gacctggact cgcagaggaa gggcaagtgt
      601 gcagtgatca aaacttctac ccgacaaacg tacttcctgc cagtgattgg gttggtagat
      661 gccgaaaagc tgaagccggg agacctggtg ggtgtgaaca aagactccta tctgatcctg
      721 gagaccctgc ccaccgaata tgactctcgg gtgaaggcca tggaggtgga cgagcggccc
      781 acagagcaat acagtgacat tggcggcctg gacaagcaga tccaggagct ggtggaagcc
      841 attgtcctgc ctatgaacca caaagagaag tttgagaact tgggtatcca gcccccaaaa
      901 ggagtgctga tgtatgggcc gcctggtaca gggaagactc tcctcgcccg agcctgtgct
      961 gctcagacca aggccacctt cttgaagctg gcaggccctc agctggtgca gatgtttatt
     1021 ggagatggcg ccaagctggt ccgtgatgct tttgccctgg ccaaggagaa ggcaccatct
     1081 attatcttta tagatgagtt ggatgccatt ggcaccaagc gcttcgacag tgaaaaggca
     1141 ggggaccgag aggtgcagag gaccatgcta gagctcctga accagctgga tggcttccag
     1201 cccaacaccc aagtgaaggt aattgcagcc actaacaggg tggacatcct ggaccctgcc
     1261 ctgctccgct caggacgcct agaccgcaag attgagtttc caatgcccaa tgaggaggcc
     1321 cgagccagaa ttatgcagat ccactcacgg aagatgaacg tcagtcctga tgtgaactat
     1381 gaagagctgg ctcgctgcac tgatgacttc aatggggccc agtgcaaggc cgtgtgtgtg
     1441 gaggcgggta tgatcgcact gcgcaggggt gccacggagc tcactcacga ggactacatg
     1501 gagggcatcc tggaggtgca ggccaagaag aaagccaacc tgcagtacta tgcctaggga
     1561 cacctctagt ctgtctgctg gtccgggggc tacggttgat aataaagggg gtttttgttc
     1621 tttgcc
//
