LOCUS       NM_057123               1545 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus proteasome 26S subunit, ATPase 1 (Psmc1), mRNA.
ACCESSION   NM_057123
VERSION     NM_057123.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1545)
  AUTHORS   Paine,S.M., Anderson,G., Bedford,K., Lawler,K., Mayer,R.J., Lowe,J.
            and Bedford,L.
  TITLE     Pale body-like inclusion formation and neurodegeneration following
            depletion of 26S proteasomes in mouse brain neurones are
            independent of alpha-synuclein
  JOURNAL   PLoS One 8 (1), e54711 (2013)
   PUBMED   23382946
REFERENCE   2  (bases 1 to 1545)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 1545)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   4  (bases 1 to 1545)
  AUTHORS   Sasaki,K., Hamazaki,J., Koike,M., Hirano,Y., Komatsu,M.,
            Uchiyama,Y., Tanaka,K. and Murata,S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   5  (bases 1 to 1545)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 1545)
  AUTHORS   Wang,X., Chen,C.F., Baker,P.R., Chen,P.L., Kaiser,P. and Huang,L.
  TITLE     Mass spectrometric characterization of the affinity-purified human
            26S proteasome complex
  JOURNAL   Biochemistry 46 (11), 3553-3565 (2007)
   PUBMED   17323924
REFERENCE   7  (bases 1 to 1545)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
REFERENCE   8  (bases 1 to 1545)
  AUTHORS   Makino,Y., Yoshida,T., Yogosawa,S., Tanaka,K., Muramatsu,M. and
            Tamura,T.A.
  TITLE     Multiple mammalian proteasomal ATPases, but not proteasome itself,
            are associated with TATA-binding protein and a novel
            transcriptional activator, TIP120
  JOURNAL   Genes Cells 4 (9), 529-539 (1999)
   PUBMED   10526239
REFERENCE   9  (bases 1 to 1545)
  AUTHORS   Makino,Y., Yogosawa,S., Kanemaki,M., Yoshida,T., Yamano,K.,
            Kishimoto,T., Moncollin,V., Egly,J.M., Muramatsu,M. and Tamura,T.
  TITLE     Structures of the rat proteasomal ATPases: determination of highly
            conserved structural motifs and rules for their spacing
  JOURNAL   Biochem Biophys Res Commun 220 (3), 1049-1054 (1996)
   PUBMED   8607789
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Nov 26, 2020 this sequence version replaced NM_057123.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D50696.1, BC063157.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                JAXUCZ010000006.1  125122497-125122513
            18-71               JAXUCZ010000006.1  125123718-125123771
            72-168              JAXUCZ010000006.1  125124690-125124786
            169-293             JAXUCZ010000006.1  125126113-125126237
            294-479             JAXUCZ010000006.1  125126631-125126816
            480-608             JAXUCZ010000006.1  125126993-125127121
            609-705             JAXUCZ010000006.1  125127786-125127882
            706-895             JAXUCZ010000006.1  125130329-125130518
            896-1047            JAXUCZ010000006.1  125131251-125131402
            1048-1202           JAXUCZ010000006.1  125132331-125132485
            1203-1545           JAXUCZ010000006.1  125134517-125134859
FEATURES             Location/Qualifiers
     source          1..1545
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..1545
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /note="proteasome 26S subunit, ATPase 1"
                     /db_xref="GeneID:117263"
                     /db_xref="RGD:621097"
     exon            1..17
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..1337
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /note="26S protease regulatory subunit 4; P26s4; 26S
                     proteasome AAA-ATPase subunit RPT2; protease (prosome,
                     macropain) 26S subunit, ATPase 1; peptidase (prosome,
                     macropain) 26S subunit, ATPase 1; proteasome (prosome,
                     macropain) 26S subunit, ATPase, 1"
                     /codon_start=1
                     /product="26S proteasome regulatory subunit 4"
                     /protein_id="NP_476464.1"
                     /db_xref="GeneID:117263"
                     /db_xref="RGD:621097"
                     /translation="MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPD
                     AASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDL
                     RGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVI
                     GVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKP
                     PKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEE
                     HAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI
                     ETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSG
                     ADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL"
     exon            18..71
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
     exon            72..168
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
     exon            169..293
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
     exon            294..479
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
     exon            480..608
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
     exon            609..705
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
     exon            706..895
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
     exon            896..1047
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1202
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1545
                     /gene="Psmc1"
                     /gene_synonym="s4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acgactgaag gaagatgggt caaagtcaga gtggtggcca tggtcctggg ggtggcaaga
       61 aggatgacaa ggacaagaaa aagaaatatg aacctcctgt cccaactaga gtggggaaaa
      121 agaagaagaa aaccaaggga ccagatgctg ccagcaaact gccactggta acacctcaca
      181 cccagtgccg cctgaaatta ctaaagctgg agagaataaa agactatctt ctcatggagg
      241 aagaattcat tagaaatcag gaacagatga aaccactaga agaaaagcaa gaggaggaaa
      301 gatcaaaggt ggatgatctt aggggaaccc ccatgtctgt aggaaccttg gaagagatca
      361 tcgatgataa tcacgccatt gtgtccacat cggtgggctc agaacactac gtcagcatcc
      421 tgtcatttgt agacaaggat ctgctggaac cgggctgttc agtcctgctc aaccacaagg
      481 tgcatgctgt gataggggtg ctcatggatg acacggatcc cctggtcaca gtgatgaagg
      541 tggaaaaggc cccccaggaa acctatgcag atattggggg actggacaac cagatccagg
      601 aaattaagga atctgtggag ctccctctta cccaccctga gtattatgag gagatgggga
      661 taaaaccacc taagggggtc attctctacg gcccgccagg gacaggtaaa actctattgg
      721 ccaaagcagt agcgaaccag acttcagcga ctttcttgcg agtggttggc tcagagctta
      781 ttcagaagta cctaggtgac gggcccaagc tggtccggga gctcttccgg gtcgctgagg
      841 aacacgcacc gtccattgtg ttcattgatg aaatcgacgc cattgggacc aaaagatatg
      901 attcaaactc tggaggtgag cgggaaatcc agcggacaat gttggaactg ttgaaccagt
      961 tggatggatt tgattcgagg ggagatgtaa aagttatcat ggccacaaac cgaatagaaa
     1021 ctttggatcc agcacttatc agaccaggcc gcattgacag aaagatcgag ttccccctgc
     1081 ctgatgaaaa gaccaagaag cgcatcttcc agatccacac aagcaggatg acgctggctg
     1141 atgatgtaac cttggatgac ttgatcatgg caaaggatga cctctctggg gctgacatca
     1201 aggcaatctg cacagaggct ggcttgatgg ctctgcggga acgcaggatg aaagtgacaa
     1261 acgaagactt caagaaatct aaggagaacg ttctgtataa aaaacaagaa ggcacccctg
     1321 aggggctgta tctctagtga cacagttgtc ttcagggaac ttaatgagtt tcccccacct
     1381 gggaagatgg gaagctgccc caaggaatcc atcttccagt taagttttgc tagtagaaag
     1441 cccgtgtcgt ggaggacgct gtgcggtctg tctccaatct gttgttggtc attgtgccct
     1501 gcagctctcc gctcccaata aaggattgtc ctggtttgct ttcta
//
