LOCUS       NM_053590                799 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Rattus norvegicus proteasome 20S subunit beta 1 (Psmb1), mRNA.
ACCESSION   NM_053590
VERSION     NM_053590.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 799)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   2  (bases 1 to 799)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (bases 1 to 799)
  AUTHORS   Sasaki,K., Hamazaki,J., Koike,M., Hirano,Y., Komatsu,M.,
            Uchiyama,Y., Tanaka,K. and Murata,S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   4  (bases 1 to 799)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 799)
  AUTHORS   Murata,S., Sasaki,K., Kishimoto,T., Niwa,S., Hayashi,H.,
            Takahama,Y. and Tanaka,K.
  TITLE     Regulation of CD8+ T cell development by thymus-specific
            proteasomes
  JOURNAL   Science 316 (5829), 1349-1353 (2007)
   PUBMED   17540904
REFERENCE   6  (bases 1 to 799)
  AUTHORS   Wang,X., Chen,C.F., Baker,P.R., Chen,P.L., Kaiser,P. and Huang,L.
  TITLE     Mass spectrometric characterization of the affinity-purified human
            26S proteasome complex
  JOURNAL   Biochemistry 46 (11), 3553-3565 (2007)
   PUBMED   17323924
REFERENCE   7  (bases 1 to 799)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
REFERENCE   8  (bases 1 to 799)
  AUTHORS   Tamura,T., Tanaka,K., Kumatori,A., Yamada,F., Tsurumi,C.,
            Fujiwara,T., Ichihara,A., Tokunaga,F., Aruga,R. and Iwanaga,S.
  TITLE     cDNA cloning and sequencing of component C5 of proteasomes from rat
            hepatoma cells
  JOURNAL   FEBS Lett 264 (1), 91-94 (1990)
   PUBMED   2338147
REFERENCE   9  (bases 1 to 799)
  AUTHORS   Tokunaga,F., Aruga,R., Iwanaga,S., Tanaka,K., Ichihara,A., Takao,T.
            and Shimonishi,Y.
  TITLE     The NH2-terminal residues of rat liver proteasome (multicatalytic
            proteinase complex) subunits, C2, C3 and C8, are N alpha-acetylated
  JOURNAL   FEBS Lett 263 (2), 373-375 (1990)
   PUBMED   2335242
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X52783.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X52783.1, FQ214442.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMN09767679
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..799
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..799
                     /gene="Psmb1"
                     /note="proteasome 20S subunit beta 1"
                     /db_xref="GeneID:94198"
                     /db_xref="RGD:621092"
     exon            1..128
                     /gene="Psmb1"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..741
                     /gene="Psmb1"
                     /EC_number="3.4.25.1"
                     /note="proteasome subunit beta type-1; macropain subunit
                     C5; proteasome gamma chain; proteasome component C5;
                     multicatalytic endopeptidase complex subunit C5; beta-6;
                     proteasome beta 1 subunit; proteasome subunit RC5;
                     proteasome (prosome, macropain) subunit, beta type 1;
                     proteasome subunit beta 1; proteasome subunit beta-6"
                     /codon_start=1
                     /product="proteasome subunit beta type-1 precursor"
                     /protein_id="NP_446042.1"
                     /db_xref="GeneID:94198"
                     /db_xref="RGD:621092"
                     /translation="MLSTAAYRDPDRELVMGPQGSAGPVQMRFSPYAFNGGTVLAIAG
                     EDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMY
                     KHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIEGLDEEGKGAVYSFDPVGSYQRD
                     SFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDVYTGD
                     ALRICIVTKEGIREETVPLRKD"
     exon            129..236
                     /gene="Psmb1"
                     /inference="alignment:Splign:2.1.0"
     exon            237..318
                     /gene="Psmb1"
                     /inference="alignment:Splign:2.1.0"
     exon            319..448
                     /gene="Psmb1"
                     /inference="alignment:Splign:2.1.0"
     exon            449..555
                     /gene="Psmb1"
                     /inference="alignment:Splign:2.1.0"
     exon            556..799
                     /gene="Psmb1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagcaggagt taggcgcgat gctttccact gccgcttacc gggacccgga ccgagagctg
       61 gtaatggggc ctcagggctc cgccggccct gtgcagatgc gtttctcgcc ttatgccttc
      121 aacggaggta ctgtattggc aattgctgga gaagattttt ccatcgttgc ttcagacact
      181 cggttgagtg aagggttttc aattcatacc cgagatagcc ccaaatgtta caaactaaca
      241 gacaaaacag taattggctg cagtggcttt catggagatt gtctcacctt gacaaagatt
      301 attgaagcaa gattaaagat gtacaagcat tccaataaca aggccatgac aacaggggcg
      361 attgctgcaa tgctgtctac catcctgtac tcacggcgtt tcttccctta ctatgtctac
      421 aacatcattg agggacttga tgaagaagga aagggagccg tgtacagctt tgacccagta
      481 ggctcttacc agagagactc tttcaaagcc ggaggctcag caagtgccat gctgcagccg
      541 ctgctcgaca accaggttgg cttcaaaaat atgcagaatg tggagcatgt ccccctgact
      601 ctggacagag ccatgaggct ggtgaaagac gtcttcattt ctgcagccga gagggatgtg
      661 tacactggag acgccctcag gatctgcatc gtgaccaaag agggcatcag ggaggagact
      721 gttccccttc ggaaagactg atgtggggcc agggtttgga gctgtggcac gtttgtttta
      781 ttaaaaagaa atgtaaagg
//
