LOCUS       NM_017282               1017 bp    mRNA    linear   ROD 20-OCT-2024
DEFINITION  Rattus norvegicus proteasome 20S subunit alpha 5 (Psma5), mRNA.
ACCESSION   NM_017282
VERSION     NM_017282.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1017)
  AUTHORS   Wu,W., Sahara,K., Hirayama,S., Zhao,X., Watanabe,A., Hamazaki,J.,
            Yashiroda,H. and Murata,S.
  TITLE     PAC1-PAC2 proteasome assembly chaperone retains the core
            alpha4-alpha7 assembly intermediates in the cytoplasm
  JOURNAL   Genes Cells 23 (10), 839-848 (2018)
   PUBMED   30133132
REFERENCE   2  (bases 1 to 1017)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 1017)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 1017)
  AUTHORS   Sasaki,K., Hamazaki,J., Koike,M., Hirano,Y., Komatsu,M.,
            Uchiyama,Y., Tanaka,K. and Murata,S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   5  (bases 1 to 1017)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 1017)
  AUTHORS   Murata,S., Sasaki,K., Kishimoto,T., Niwa,S., Hayashi,H.,
            Takahama,Y. and Tanaka,K.
  TITLE     Regulation of CD8+ T cell development by thymus-specific
            proteasomes
  JOURNAL   Science 316 (5829), 1349-1353 (2007)
   PUBMED   17540904
REFERENCE   7  (bases 1 to 1017)
  AUTHORS   Wang,X., Chen,C.F., Baker,P.R., Chen,P.L., Kaiser,P. and Huang,L.
  TITLE     Mass spectrometric characterization of the affinity-purified human
            26S proteasome complex
  JOURNAL   Biochemistry 46 (11), 3553-3565 (2007)
   PUBMED   17323924
REFERENCE   8  (bases 1 to 1017)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
REFERENCE   9  (bases 1 to 1017)
  AUTHORS   Tamura,T., Shimbara,N., Aki,M., Ishida,N., Bey,F., Scherrer,K.,
            Tanaka,K. and Ichihara,A.
  TITLE     Molecular cloning of cDNAs for rat proteasomes: deduced primary
            structures of four other subunits
  JOURNAL   J Biochem 112 (4), 530-534 (1992)
   PUBMED   1491007
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM064330.1, BC060575.1 and JAXUCZ010000002.1.
            
            On Apr 28, 2015 this sequence version replaced NM_017282.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC060575.1, CF110994.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                FM064330.1         6-29
            25-1008             BC060575.1         3-986
            1009-1017           JAXUCZ010000002.1  198607859-198607867
FEATURES             Location/Qualifiers
     source          1..1017
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1017
                     /gene="Psma5"
                     /note="proteasome 20S subunit alpha 5"
                     /db_xref="GeneID:29672"
                     /db_xref="RGD:61848"
     exon            1..156
                     /gene="Psma5"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..853
                     /gene="Psma5"
                     /EC_number="3.4.25.1"
                     /note="macropain zeta chain; proteasome zeta chain;
                     multicatalytic endopeptidase complex zeta chain;
                     proteasome alpha 5 subunit; proteasome (prosome,
                     macropain) subunit, alpha type 5; proteasome subunit alpha
                     5; alpha-5"
                     /codon_start=1
                     /product="proteasome subunit alpha type-5"
                     /protein_id="NP_058978.2"
                     /db_xref="GeneID:29672"
                     /db_xref="RGD:61848"
                     /translation="MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSE
                     GVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFT
                     YNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSG
                     TFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELA
                     TVQPGQNFHMFTKEELEEVIKDI"
     exon            157..223
                     /gene="Psma5"
                     /inference="alignment:Splign:2.1.0"
     exon            224..350
                     /gene="Psma5"
                     /inference="alignment:Splign:2.1.0"
     exon            351..418
                     /gene="Psma5"
                     /inference="alignment:Splign:2.1.0"
     exon            419..526
                     /gene="Psma5"
                     /inference="alignment:Splign:2.1.0"
     exon            527..585
                     /gene="Psma5"
                     /inference="alignment:Splign:2.1.0"
     exon            586..688
                     /gene="Psma5"
                     /inference="alignment:Splign:2.1.0"
     exon            689..775
                     /gene="Psma5"
                     /inference="alignment:Splign:2.1.0"
     exon            776..1017
                     /gene="Psma5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgtgcgcacg cgcagagggc cgcaggatcc ttggtgctgt ggcggtgtgg ttgagtaggg
       61 tgctgctttc agtcgtgtgg cctttgggaa ctccgcgtag ccactgccgc ctcctcctgt
      121 cctcgccatg ttcctcactc ggtccgagta cgacaggggt gtgaacactt tttctcctga
      181 aggaagatta tttcaagtgg aatatgccat tgaggccatc aagcttggtt ctacggccat
      241 tggcatccag acatcagagg gtgtatgtct agctgtggag aagagaatta cctcgccact
      301 aatggagcct agcagcattg agaaaatcgt agagattgat gctcatatag gttgtgccat
      361 gagtgggcta attgctgatg ctaaaacttt aattgataaa gccagagtgg agacacagaa
      421 ccactggttc acctataatg agacaatgac agttgagagt gtgacccagg ctgtgtccaa
      481 tctggctttg cagttcggag aagaagatgc agatccaggt gctatgtctc gtccctttgg
      541 agtagcattg ttgtttggag gagttgatga gaaagggccc caactgtttc acatggaccc
      601 atctgggacc ttcgtacagt gtgatgctcg agcaattggt tctgcgtcag agggtgccca
      661 gagctccttg caggaagttt accacaagtc tatgactctg aaggaggcca tcaagtcttc
      721 actcatcatc ctcaagcaag tcatggagga gaagctgaac gcaactaaca tcgagctggc
      781 cacagtgcag cctggtcaga atttccacat gttcacaaag gaagaactgg aggaggtgat
      841 caaggacatt taaggagggg ccatcctcga acttctgtgg gacagtttca gttctaatgg
      901 ctcttagact ttatttccaa ctccacgtcg tggaaaatat ccagtatatg tatgtgtgtt
      961 tttttatgat gtctgtacat aacagcaatt ctgaaataaa aaaaatttac aaatatt
//
