LOCUS       NM_017281               1121 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Rattus norvegicus proteasome 20S subunit alpha 4 (Psma4), mRNA.
ACCESSION   NM_017281
VERSION     NM_017281.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1121)
  AUTHORS   Wu,W., Sahara,K., Hirayama,S., Zhao,X., Watanabe,A., Hamazaki,J.,
            Yashiroda,H. and Murata,S.
  TITLE     PAC1-PAC2 proteasome assembly chaperone retains the core
            alpha4-alpha7 assembly intermediates in the cytoplasm
  JOURNAL   Genes Cells 23 (10), 839-848 (2018)
   PUBMED   30133132
REFERENCE   2  (bases 1 to 1121)
  AUTHORS   Lukic,Z., Hausmann,S., Sebastian,S., Rucci,J., Sastri,J.,
            Robia,S.L., Luban,J. and Campbell,E.M.
  TITLE     TRIM5alpha associates with proteasomal subunits in cells while in
            complex with HIV-1 virions
  JOURNAL   Retrovirology 8, 93 (2011)
   PUBMED   22078707
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1121)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   4  (bases 1 to 1121)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   5  (bases 1 to 1121)
  AUTHORS   Sasaki,K., Hamazaki,J., Koike,M., Hirano,Y., Komatsu,M.,
            Uchiyama,Y., Tanaka,K. and Murata,S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   6  (bases 1 to 1121)
  AUTHORS   Wang,X., Chen,C.F., Baker,P.R., Chen,P.L., Kaiser,P. and Huang,L.
  TITLE     Mass spectrometric characterization of the affinity-purified human
            26S proteasome complex
  JOURNAL   Biochemistry 46 (11), 3553-3565 (2007)
   PUBMED   17323924
REFERENCE   7  (bases 1 to 1121)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
REFERENCE   8  (bases 1 to 1121)
  AUTHORS   Dachsel,J.C., Lucking,C.B., Deeg,S., Schultz,E., Lalowski,M.,
            Casademunt,E., Corti,O., Hampe,C., Patenge,N., Vaupel,K.,
            Yamamoto,A., Dichgans,M., Brice,A., Wanker,E.E., Kahle,P.J. and
            Gasser,T.
  TITLE     Parkin interacts with the proteasome subunit alpha4
  JOURNAL   FEBS Lett 579 (18), 3913-3919 (2005)
   PUBMED   15987638
  REMARK    GeneRIF: Parkin interacts with the proteasome subunit alpha4
REFERENCE   9  (bases 1 to 1121)
  AUTHORS   Sorimachi,H., Tsukahara,T., Kawasaki,H., Ishiura,S., Emori,Y.,
            Sugita,H. and Suzuki,K.
  TITLE     Molecular cloning of cDNAs for two subunits of rat multicatalytic
            proteinase. Existence of N-terminal conserved and C-terminal
            diverged sequences among subunits
  JOURNAL   Eur J Biochem 193 (3), 775-781 (1990)
   PUBMED   2249692
REFERENCE   10 (bases 1 to 1121)
  AUTHORS   Kumatori,A., Tanaka,K., Tamura,T., Fujiwara,T., Ichihara,A.,
            Tokunaga,F., Onikura,A. and Iwanaga,S.
  TITLE     cDNA cloning and sequencing of component C9 of proteasomes from rat
            hepatoma cells
  JOURNAL   FEBS Lett 264 (2), 279-282 (1990)
   PUBMED   2358075
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X53304.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X53304.1, BC063170.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1121
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..1121
                     /gene="Psma4"
                     /note="proteasome 20S subunit alpha 4"
                     /db_xref="GeneID:29671"
                     /db_xref="RGD:61846"
     exon            1..73
                     /gene="Psma4"
                     /inference="alignment:Splign:2.1.0"
     exon            74..99
                     /gene="Psma4"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..882
                     /gene="Psma4"
                     /EC_number="3.4.25.1"
                     /note="alpha-3; multicatalytic proteinase subunit L;
                     macropain subunit C9; proteasome subunit L; proteasome
                     component C9; multicatalytic endopeptidase complex subunit
                     C9; proteasome alpha 4 subunit; proteasome (prosome,
                     macropain) subunit, alpha type 4; proteasome subunit alpha
                     4; proteasome subunit alpha-3"
                     /codon_start=1
                     /product="proteasome subunit alpha type-4"
                     /protein_id="NP_058977.1"
                     /db_xref="GeneID:29671"
                     /db_xref="RGD:61846"
                     /translation="MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVL
                     LAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQ
                     EPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWK
                     ATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAVKVLNKTMDVSKLSAEKVEIATLTR
                     ENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQREKDK"
     exon            100..142
                     /gene="Psma4"
                     /inference="alignment:Splign:2.1.0"
     exon            143..305
                     /gene="Psma4"
                     /inference="alignment:Splign:2.1.0"
     exon            306..383
                     /gene="Psma4"
                     /inference="alignment:Splign:2.1.0"
     exon            384..472
                     /gene="Psma4"
                     /inference="alignment:Splign:2.1.0"
     exon            473..603
                     /gene="Psma4"
                     /inference="alignment:Splign:2.1.0"
     exon            604..727
                     /gene="Psma4"
                     /inference="alignment:Splign:2.1.0"
     exon            728..1121
                     /gene="Psma4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttggccatc cgggttggtt cttctccagc tgagtaaagc ggcgctgatc tgcaccctca
       61 ctgtcttcct ccggatccac ataaaattca gaagccatgt ctcgaagata tgactccagg
      121 accacaatat tttctccaga aggtcgctta taccaagtgg aatatgccat ggaagccatt
      181 ggacacgcag gcacttgttt gggaatttta gccaatgatg gcgttctgct tgcagcagag
      241 aggcgcaaca tccacaagct tcttgatgaa gtcttttttt ctgagaaaat ttataaactt
      301 aacgaggaca tggcttgcag tgtggcaggc ataacatctg atgccaacgt tctgactaat
      361 gaactcaggc tcattgctca aaggtactta ttacagtatc aggagccaat tccctgtgag
      421 cagttggtta cagcactgtg tgatatcaaa caggcgtaca cacagtttgg aggcaaacgt
      481 ccctttggtg tttctttgct gtatattggc tgggataagc actatggctt tcagctctat
      541 cagagtgacc caagtggaaa ctacggggga tggaaagcca catgcattgg aaacaacagt
      601 gctgcagcgg tatcaatgct gaaacaagac tacaaagaag gagaaatgac tctgaagtca
      661 gcgctggctc tggctgtcaa ggtgctaaac aagacaatgg atgttagtaa actgtcagct
      721 gaaaaagtgg aaatcgccac actaacaaga gagaatggaa agaccgtgat cagagtcctc
      781 aagcaaaagg aagtggaaca gttgatcaaa aaacatgaag aggaagaagc gaaagctgaa
      841 cgggagaaga aagaaaaaga acagagagaa aaggataaat agacagaatc atggatttta
      901 taactcctta gaggcgccag ttcacttagg agctgtcctg gccttcccct ggaagtgttt
      961 tcttgtattt tcttccttac cttggccatc ggggaaatgg gacattgcat actgaattgg
     1021 gtccatgtct gtccagctgg atgctttatt gtaatgatgg acatctttat aaacatctta
     1081 atctcgacac ataatttttg gaataaaacc tggaaagatt g
//
