LOCUS       NM_017279                852 bp    mRNA    linear   ROD 20-OCT-2024
DEFINITION  Rattus norvegicus proteasome 20S subunit alpha 2 (Psma2), mRNA.
ACCESSION   NM_017279
VERSION     NM_017279.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Lukic,Z., Hausmann,S., Sebastian,S., Rucci,J., Sastri,J.,
            Robia,S.L., Luban,J. and Campbell,E.M.
  TITLE     TRIM5alpha associates with proteasomal subunits in cells while in
            complex with HIV-1 virions
  JOURNAL   Retrovirology 8, 93 (2011)
   PUBMED   22078707
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 852)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 852)
  AUTHORS   Sasaki,K., Hamazaki,J., Koike,M., Hirano,Y., Komatsu,M.,
            Uchiyama,Y., Tanaka,K. and Murata,S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   5  (bases 1 to 852)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 852)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
REFERENCE   7  (bases 1 to 852)
  AUTHORS   Leong,W.F. and Chow,V.T.
  TITLE     Transcriptomic and proteomic analyses of rhabdomyosarcoma cells
            reveal differential cellular gene expression in response to
            enterovirus 71 infection
  JOURNAL   Cell Microbiol 8 (4), 565-580 (2006)
   PUBMED   16548883
REFERENCE   8  (bases 1 to 852)
  AUTHORS   Benedict,C.M. and Clawson,G.A.
  TITLE     Nuclear multicatalytic proteinase subunit RRC3 is important for
            growth regulation in hepatocytes
  JOURNAL   Biochemistry 35 (36), 11612-11621 (1996)
   PUBMED   8794741
REFERENCE   9  (bases 1 to 852)
  AUTHORS   Tokunaga,F., Aruga,R., Iwanaga,S., Tanaka,K., Ichihara,A., Takao,T.
            and Shimonishi,Y.
  TITLE     The NH2-terminal residues of rat liver proteasome (multicatalytic
            proteinase complex) subunits, C2, C3 and C8, are N alpha-acetylated
  JOURNAL   FEBS Lett 263 (2), 373-375 (1990)
   PUBMED   2335242
REFERENCE   10 (bases 1 to 852)
  AUTHORS   Tanaka,K., Fujiwara,T., Kumatori,A., Shin,S., Yoshimura,T.,
            Ichihara,A., Tokunaga,F., Aruga,R., Iwanaga,S., Kakizuka,A. et al.
  TITLE     Molecular cloning of cDNA for proteasomes from rat liver: primary
            structure of component C3 with a possible tyrosine phosphorylation
            site
  JOURNAL   Biochemistry 29 (15), 3777-3785 (1990)
   PUBMED   2340272
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Nov 26, 2020 this sequence version replaced NM_017279.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: J02897.1, FQ223872.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676784, SAMN16676806
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                JAXUCZ010000017.1  55260395-55260441   c
            48-124              JAXUCZ010000017.1  55258337-55258413   c
            125-257             JAXUCZ010000017.1  55257581-55257713   c
            258-380             JAXUCZ010000017.1  55255548-55255670   c
            381-462             JAXUCZ010000017.1  55254187-55254268   c
            463-536             JAXUCZ010000017.1  55251749-55251822   c
            537-594             JAXUCZ010000017.1  55250399-55250456   c
            595-852             JAXUCZ010000017.1  55250054-55250311   c
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.1"
     gene            1..852
                     /gene="Psma2"
                     /note="proteasome 20S subunit alpha 2"
                     /db_xref="GeneID:29669"
                     /db_xref="RGD:61842"
     exon            1..47
                     /gene="Psma2"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..711
                     /gene="Psma2"
                     /EC_number="3.4.25.1"
                     /note="macropain subunit C3; proteasome component C3;
                     multicatalytic endopeptidase complex subunit C3;
                     proteasome alpha 2 subunit; proteasome (prosome,
                     macropain) subunit, alpha type 2; alpha-2; proteasome
                     subunit alpha 2"
                     /codon_start=1
                     /product="proteasome subunit alpha type-2"
                     /protein_id="NP_058975.1"
                     /db_xref="GeneID:29669"
                     /db_xref="RGD:61842"
                     /translation="MAERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGV
                     VLATEKKQKSILYDERSVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQ
                     EPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKA
                     TAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLKESFEGQMTEDNIEVGICNEAGF
                     RRLTPTEVRDYLAAIA"
     exon            48..124
                     /gene="Psma2"
                     /inference="alignment:Splign:2.1.0"
     exon            125..257
                     /gene="Psma2"
                     /inference="alignment:Splign:2.1.0"
     exon            258..380
                     /gene="Psma2"
                     /inference="alignment:Splign:2.1.0"
     exon            381..462
                     /gene="Psma2"
                     /inference="alignment:Splign:2.1.0"
     exon            463..536
                     /gene="Psma2"
                     /inference="alignment:Splign:2.1.0"
     exon            537..594
                     /gene="Psma2"
                     /inference="alignment:Splign:2.1.0"
     exon            595..852
                     /gene="Psma2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtaaagatgg cagaacgcgg ttacagcttc tcgctgacta cattcagccc atctggtaaa
       61 cttgtgcaga ttgaatatgc tttggccgct gtagctggag gggccccttc agtgggaatt
      121 aaagctgcaa atggcgtggt attagccact gagaaaaagc agaaatccat cctgtatgat
      181 gagaggagtg tacacaaagt ggagcccata accaagcaca tcggtttggt gtacagcggc
      241 atgggtccag attacagagt ccttgtacac agagctcgga aacttgctca gcagtactac
      301 cttgtttacc aagaacccat tcccacagcc caactggtac agcgagtagc gtctgtgatg
      361 caagagtata cccagtcagg tggtgttcgt ccatttggtg tttctttact tatttgtggg
      421 tggaatgagg gacgaccata tttatttcag tcagatccat ctggagctta ctttgcctgg
      481 aaggccacag caatgggaaa gaactacgtg aatgggaaaa ctttccttga gaaaagatat
      541 aatgaagact tagaactgga agatgccatt cacacagcca tcttaaccct taaggaaagc
      601 tttgaagggc agatgacaga agataacata gaagttggga tctgcaatga agctggcttt
      661 aggaggctca ccccaactga agtgagggat tacttggctg ctatagcgta atgaagatgt
      721 gccggaacaa tcaaggaaca ctcattctac ttattcattt ttaaagtatg ttttgtttgt
      781 gcagacttat ttctacatgc tttaatggat tcacattttt aaataataat cataataaac
      841 tgttaaaacc ag
//
