LOCUS       NM_017278               1174 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus proteasome 20S subunit alpha 1 (Psma1), mRNA.
ACCESSION   NM_017278
VERSION     NM_017278.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1174)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   2  (bases 1 to 1174)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (bases 1 to 1174)
  AUTHORS   Sasaki,K., Hamazaki,J., Koike,M., Hirano,Y., Komatsu,M.,
            Uchiyama,Y., Tanaka,K. and Murata,S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   4  (bases 1 to 1174)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 1174)
  AUTHORS   Wang,X., Chen,C.F., Baker,P.R., Chen,P.L., Kaiser,P. and Huang,L.
  TITLE     Mass spectrometric characterization of the affinity-purified human
            26S proteasome complex
  JOURNAL   Biochemistry 46 (11), 3553-3565 (2007)
   PUBMED   17323924
REFERENCE   6  (bases 1 to 1174)
  AUTHORS   Stanhill,A., Haynes,C.M., Zhang,Y., Min,G., Steele,M.C.,
            Kalinina,J., Martinez,E., Pickart,C.M., Kong,X.P. and Ron,D.
  TITLE     An arsenite-inducible 19S regulatory particle-associated protein
            adapts proteasomes to proteotoxicity
  JOURNAL   Mol Cell 23 (6), 875-885 (2006)
   PUBMED   16973439
REFERENCE   7  (bases 1 to 1174)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
REFERENCE   8  (bases 1 to 1174)
  AUTHORS   Qureshi,N., Perera,P.Y., Shen,J., Zhang,G., Lenschat,A.,
            Splitter,G., Morrison,D.C. and Vogel,S.N.
  TITLE     The proteasome as a lipopolysaccharide-binding protein in
            macrophages: differential effects of proteasome inhibition on
            lipopolysaccharide-induced signaling events
  JOURNAL   J Immunol 171 (3), 1515-1525 (2003)
   PUBMED   12874245
REFERENCE   9  (bases 1 to 1174)
  AUTHORS   Tokunaga,F., Aruga,R., Iwanaga,S., Tanaka,K., Ichihara,A., Takao,T.
            and Shimonishi,Y.
  TITLE     The NH2-terminal residues of rat liver proteasome (multicatalytic
            proteinase complex) subunits, C2, C3 and C8, are N alpha-acetylated
  JOURNAL   FEBS Lett 263 (2), 373-375 (1990)
   PUBMED   2335242
REFERENCE   10 (bases 1 to 1174)
  AUTHORS   Fujiwara,T., Tanaka,K., Kumatori,A., Shin,S., Yoshimura,T.,
            Ichihara,A., Tokunaga,F., Aruga,R., Iwanaga,S., Kakizuka,A. et al.
  TITLE     Molecular cloning of cDNA for proteasomes (multicatalytic
            proteinase complexes) from rat liver: primary structure of the
            largest component (C2)
  JOURNAL   Biochemistry 28 (18), 7332-7340 (1989)
   PUBMED   2819072
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from D90265.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D90265.1, M29859.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840115, SAMN16676786
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1174
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q34"
     gene            1..1174
                     /gene="Psma1"
                     /note="proteasome 20S subunit alpha 1"
                     /db_xref="GeneID:29668"
                     /db_xref="RGD:61841"
     exon            1..91
                     /gene="Psma1"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..880
                     /gene="Psma1"
                     /EC_number="3.4.25.1"
                     /note="proteasome nu chain; macropain subunit C2;
                     proteasome component C2; proteasome subunit alpha 1;
                     multicatalytic endopeptidase complex subunit C2;
                     proteasome alpha 1 subunit; proteasome (prosome,
                     macropain) subunit, alpha type 1"
                     /codon_start=1
                     /product="proteasome subunit alpha type-1"
                     /protein_id="NP_058974.1"
                     /db_xref="GeneID:29668"
                     /db_xref="RGD:61841"
                     /translation="MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHA
                     VLVALKRAQSELAAHQKKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRP
                     LPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHVFQTCPSANYFDCRAMS
                     IGARSQSARTYLERHMSEFMQCNLDELVKHGLRALRETLPAEQDLTTKNVSIGIVGKD
                     LEFTIYDDDDVSPFLDGLEERPQRKAQPSQAADEPAEKADEPMEH"
     exon            92..136
                     /gene="Psma1"
                     /inference="alignment:Splign:2.1.0"
     exon            137..238
                     /gene="Psma1"
                     /inference="alignment:Splign:2.1.0"
     exon            239..342
                     /gene="Psma1"
                     /inference="alignment:Splign:2.1.0"
     exon            343..431
                     /gene="Psma1"
                     /inference="alignment:Splign:2.1.0"
     exon            432..502
                     /gene="Psma1"
                     /inference="alignment:Splign:2.1.0"
     exon            503..632
                     /gene="Psma1"
                     /inference="alignment:Splign:2.1.0"
     exon            633..712
                     /gene="Psma1"
                     /inference="alignment:Splign:2.1.0"
     exon            713..823
                     /gene="Psma1"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1174
                     /gene="Psma1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgcagcctt ctttgacgat caccgaaccg tagttgaggc cgtgttcctg tgtccgctgc
       61 tgtgtctggt tgtaacctcg ccggagctat gtttcgcaac cagtatgaca acgatgtcac
      121 tgtttggagc cctcagggca ggattcatca aatcgaatat gcaatggaag ctgtaaagca
      181 aggctcagcg acagtcggcc tgaagtcgaa gacacatgca gtgctggtcg cgctgaagag
      241 agcacagtca gagcttgccg ctcaccagaa gaaaattctc cacgttgaca accatattgg
      301 tatctcaatt gcgggtctaa ctgctgatgc cagactgtta tgtaacttta tgcgccagga
      361 gtgtttggat tccagatttg tatttgacag accacttccc gtatctcgcc ttgtgtctct
      421 aattggaagc aagacccaga taccaacaca gcgatatggc cggagaccgt atggtgttgg
      481 gctgctcatt gctggttatg atgacatggg ccctcacgtt ttccaaacct gcccatctgc
      541 taactatttt gactgcagag ctatgtccat cggagcccgt tcccagtcag ctcgcactta
      601 cctggagaga cacatgtctg aatttatgca gtgcaatttg gatgaactgg ttaagcatgg
      661 tcttcgcgcc ttaagagaaa cactccctgc agaacaggac ctgaccacaa agaatgtttc
      721 cattgggatt gttggtaaag acttggaatt tactatctat gatgatgatg atgtgtctcc
      781 attcctggat ggtcttgaag aaagaccaca gagaaaagca cagccttcac aggctgctga
      841 tgaacctgca gaaaaagctg atgaaccaat ggaacattaa gtgataaagg ttatgaggac
      901 atgaggatgc aggggcatac actggtgaca ataatctgta ttttaaacca acagctgtaa
      961 tgtattgggt ggtatgtttt agaaatcagt ccaactgtga gttttctcta agcagcttca
     1021 cagaaaccat ataatggggt gcattttctt tgaaagggtc tacataatca ttttctagga
     1081 cgtataggta tctatatcaa tgtttttata tgaagaaaat aagtgtcttt gcagttttaa
     1141 agacaactgt gaaataaaat tgtttcacca cctg
//
