LOCUS       XM_039091113            2121 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus presenilin 2 (Psen2), transcript
            variant X6, mRNA.
ACCESSION   XM_039091113
VERSION     XM_039091113.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051348.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039091113.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2121
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2121
                     /gene="Psen2"
                     /note="presenilin 2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 3 mRNAs, 28 ESTs, 1 long
                     SRA read, 18 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 51 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:81751"
                     /db_xref="RGD:621060"
     CDS             191..1537
                     /gene="Psen2"
                     /codon_start=1
                     /product="presenilin-2 isoform X1"
                     /protein_id="XP_038947041.1"
                     /db_xref="GeneID:81751"
                     /db_xref="RGD:621060"
                     /translation="MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENT
                     AQWRSQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVV
                     VATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLY
                     KYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVC
                     IHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRM
                     LVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEP
                     SYPEAFEAPQPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACF
                     IAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI"
ORIGIN      
        1 gtgtagtgtg tgtggtgtgt acagtgtgtg gtctgtgtag gtcacatgga tctttctaac
       61 aaaaacctct ggctgtattt tagctgtttc tttaaggttg agcctctgat cagctgggac
      121 ccagcagaag gcaaaggttt ctgttgatgt cttctcacct gccctgggct gtgaccgccc
      181 gggagagacc atgctcacat tcatggcctc tgatagcgag gaagaggtgt gcgatgagcg
      241 gacgtccttg atgtcagccg agagccctac atcacgttcc tgccaggaca gcaggccagg
      301 cccagaggat ggagagaaca ctgcccagtg gaggagccag gagaacgagg acgactgtga
      361 ggaggacccg gaccactatg cctgcagtgg ggttcctggg cgaccatcgg gcctggagga
      421 ggagctgacc ctcaagtatg gggcgaagca cgtgatcatg ctgttcgtgc ctgtcacgct
      481 gtgcatgatt gtggtggtgg ccaccatcaa gtccgtgcgt ttctacacgg agaagaacgg
      541 gcagctcatc tacacgccct tcaccgagga cacaccctct gtgggccagc ggctcctcaa
      601 ctccgtgctg aacactctga tcatgatcag cgtcattgtg gtcatgacta tcttcctagt
      661 ggtactctac aaatatcgct gttacaagtt catccatggc tggctgatca tgtcctccct
      721 gatgctcctc ttcttgttca cctacatcta cctcggggaa gtgttcaaga cctacaatgt
      781 ggccatggac taccccacac tgttcctggc tgtctggaac ttcggggcag tgggcatggt
      841 gtgcatccac tggaagggtc ccctggtgct ccagcaggct tacctcattg tgatcagcgc
      901 actcatggcc ctggtgttca tcaagtacct gccggagtgg tccgcttggg tcatcttggg
      961 cgccatctct gtgtacgatc tcgtggctgt gctgtgcccc aaagggccac tgaggatgct
     1021 ggtggaaact gcccaggaaa gaaacgagcc catatttcct gccctcatat actcatctgc
     1081 catggtgtgg acggtaggca tggcgaagct ggacccctcc tctcagggag cactgcagct
     1141 cccttacgat ccagagatgg aagaagactc ctatgacagt tttggggaac cctcataccc
     1201 tgaagccttc gaagctcccc agcctggcta cccaggggaa gagccggagg aggaggagga
     1261 aaggggtgta aagcttggtc tgggagactt catcttctac agcgttctgg tgggcaaggc
     1321 agcagccaca ggcaacggag actggagcac gacgctggcc tgctttatcg ccatcctcat
     1381 tggcttgtgt ctcaccctcc tgctgctcgc cgtgttcaag aaggccctgc ccgccctccc
     1441 catctccatc accttcgggc tcatctttta cttctccaca gacaacctgg tgcgtccttt
     1501 catggacacg ttggcctccc accagctcta catctgacag aagagctgcg gctctgagag
     1561 ctgtaggacg cttcgccgaa tgcaggtgta tagttttaca ctctagtgcc atatattttt
     1621 ttttaaaaaa acctttcttt ccttacaaaa gaaaaaaaaa gaataaaaaa gtgttgtgtt
     1681 tacttcgtga cgaggaagca gaagccgccc ttctgtgcta gctgtcttgt caccagactg
     1741 aggcttgccc gtcagagcat ctgtggcacc cgcaggtggg atgctgggcc aacaagccta
     1801 tcttcaggga tgaggtcacg tgtgtggatc aggttggaga ggacgcaggc cccatccagg
     1861 tctgtaatca atccttcagg gctgagcagg aggaacatgt gcgtcagtgg ggaccaggag
     1921 gcacggtcag gaaggacgct aagcaccaac accctgacca gaggacaaaa gccagtttgt
     1981 cgtcatgaat gcccccagtg ctttgtttgt gatgtctgtt acctttagta tcttagaagc
     2041 tgagtcctgt tcttatttct gcagtggact gctgggaagt ggcttaatga caataccaat
     2101 acatagatgt ccctgctgga a
//
