LOCUS       XM_006250408            2022 bp    mRNA    linear   ROD 22-FEB-2024
DEFINITION  PREDICTED: Rattus norvegicus presenilin 2 (Psen2), transcript
            variant X5, mRNA.
ACCESSION   XM_006250408
VERSION     XM_006250408.4
DBLINK      BioProject: PRJNA1074393
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086031) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_006250408.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2022
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     gene            1..2022
                     /gene="Psen2"
                     /note="presenilin 2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 2 mRNAs, 35 ESTs, 99 long
                     SRA reads, 19 Proteins"
                     /db_xref="GeneID:81751"
                     /db_xref="RGD:621060"
     CDS             92..1438
                     /gene="Psen2"
                     /codon_start=1
                     /product="presenilin-2 isoform X1"
                     /protein_id="XP_006250470.1"
                     /db_xref="GeneID:81751"
                     /db_xref="RGD:621060"
                     /translation="MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENT
                     AQWRSQENEDDCEEDPDHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVV
                     VATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLY
                     KYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVC
                     IHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRM
                     LVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEP
                     SYPEAFEAPQPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACF
                     IAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI"
     polyA_site      2022
                     /gene="Psen2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gaaccggggc agtgggcggg gccggcgcta gcctgggaga ggcgctccgt ccgcggcgta
       61 aactctatcc cgcgccgcgg cggagcagac catgctcaca ttcatggcct ctgatagcga
      121 ggaagaggtg tgcgatgagc ggacgtcctt gatgtcagcc gagagcccta catcacgttc
      181 ctgccaggac agcaggccag gcccagagga tggagagaac actgcccagt ggaggagcca
      241 ggagaacgag gacgactgtg aggaggaccc ggaccactat gcctgcagtg gggttcctgg
      301 gcgaccatcg ggcctggagg aggagctgac cctcaagtat ggggcgaagc acgtgatcat
      361 gctgttcgtg cctgtcacgc tgtgcatgat tgtggtggtg gccaccatca agtccgtgcg
      421 tttctacacg gagaagaacg ggcagctcat ctacacgccc ttcaccgagg acacaccctc
      481 tgtgggccag cggctcctca actccgtgct gaacactctg atcatgatca gcgtcattgt
      541 ggtcatgact atcttcctag tggtactcta caaatatcgc tgttacaagt tcatccatgg
      601 ctggctgatc atgtcctccc tgatgctcct cttcttgttc acctacatct acctcgggga
      661 agtgttcaag acctacaatg tggccatgga ctaccccaca ctgttcctgg ctgtctggaa
      721 cttcggggca gtgggcatgg tgtgcatcca ctggaagggt cccctggtgc tccagcaggc
      781 ttacctcatt gtgatcagcg cactcatggc cctggtgttc atcaagtacc tgccggagtg
      841 gtccgcttgg gtcatcttgg gcgccatctc tgtgtacgat ctcgtggctg tgctgtgccc
      901 caaagggcca ctgaggatgc tggtggaaac tgcccaggaa agaaacgagc ccatatttcc
      961 tgccctcata tactcatctg ccatggtgtg gacggtaggc atggcgaagc tggacccctc
     1021 ctctcaggga gcactgcagc tcccttacga tccagagatg gaagaagact cctatgacag
     1081 ttttggggaa ccctcatacc ctgaagcctt cgaagctccc cagcctggct acccagggga
     1141 agagccggag gaggaggagg aaaggggtgt aaagcttggt ctgggagact tcatcttcta
     1201 cagcgttctg gtgggcaagg cagcagccac aggcaacgga gactggagca cgacgctggc
     1261 ctgctttatc gccatcctca ttggcttgtg tctcaccctc ctgctgctcg ccgtgttcaa
     1321 gaaggccctg cccgccctcc ccatctccat caccttcggg ctcatctttt acttctccac
     1381 agacaacctg gtgcgtcctt tcatggacac gttggcctcc caccagctct acatctgaca
     1441 gaagagctgc ggctctgaga gctgtaggac gcttcgccga atgcaggtgt atagttttac
     1501 actctagtgc catatatttt tttttaaaaa aacctttctt tccttacaaa agaaaaaaaa
     1561 agaataaaaa agtgttgtgt ttacttcgtg acgaggaagc agaagccgcc cttctgtgct
     1621 agctgtcttg tcaccagact gaggcttgcc cgtcagagca tctgtggcac ccgcaggtgg
     1681 gatgctgggc caacaagcct atcttcaggg atgaggtcac gtgtgtggat caggttggag
     1741 aggacgcagg ccccatccag gtctgtaatc aatccttcag ggctgagcag gaggaacatg
     1801 tgcgtcagtg gggaccagga ggcacggtca ggaaggacgc taagcaccaa caccctgacc
     1861 agaggacaaa agccagtttg tcgtcatgaa tgcccccagt gctttgtttg tgatgtctgt
     1921 tacctttagt atcttagaag ctgagtcctg ttcttatttc tgcagtggac tgctgggaag
     1981 tggcttaatg acaataccaa tacatagatg tccctgctgg aa
//
