LOCUS       NM_001172106             432 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus prostate stem cell antigen (Psca), mRNA.
ACCESSION   NM_001172106 XM_002726936 XM_002729834
VERSION     NM_001172106.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Xia,B., Wang,Y., Wang,X., Wu,J., Song,Q., Sun,Z. and Zhang,Y.
  TITLE     In utero and lactational exposure of DEHP increases the
            susceptibility of prostate carcinogenesis in male offspring through
            PSCA hypomethylation
  JOURNAL   Toxicol Lett 292, 78-84 (2018)
   PUBMED   29689378
  REMARK    GeneRIF: Hypomethylation of PSCA could mediate the effect of
            di(2-ethylhexyl) phthalate on prostate carcinogenesis in rats.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001172106.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence because no single transcript was available for the
            full length of the gene. The extent of this transcript is supported
            by transcript alignments and orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.31846.1,
                                           SRR26643294.29436.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-68                JAXUCZ010000007.1  108489903-108489970
            69-176              JAXUCZ010000007.1  108491081-108491188
            177-432             JAXUCZ010000007.1  108491415-108491670
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..432
                     /gene="Psca"
                     /note="prostate stem cell antigen"
                     /db_xref="GeneID:680210"
     exon            1..68
                     /gene="Psca"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..388
                     /gene="Psca"
                     /codon_start=1
                     /product="prostate stem cell antigen precursor"
                     /protein_id="NP_001165577.1"
                     /db_xref="GeneID:680210"
                     /translation="MRTVLLLLLAVYLTLSPGAALQCYSCTAQVSNRDCLNVQNCTLD
                     QNSCFTSRVRTIGLLTFISKGCSSKCEDDTENYYVGKKNITCCSSDLCNVNGAHTLKP
                     PTTLGLLTVLCSLLLWGSRDL"
     exon            69..176
                     /gene="Psca"
                     /inference="alignment:Splign:2.1.0"
     exon            177..432
                     /gene="Psca"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtgctcact gcaaccatga ggactgtcct ccttctcctg ctggctgtct acctaaccct
       61 gtctccaggt gccgctctgc agtgctattc atgcaccgca caggtgagca acagagattg
      121 tctgaatgta cagaactgca ccctggacca gaacagctgt tttacatctc gtgtccggac
      181 cattggactc ctgacattta tcagtaaggg ctgcagctca aagtgtgagg atgacacgga
      241 gaactactat gtgggcaaga agaatatcac atgctgctcc tctgacctgt gcaatgtcaa
      301 cggggcccac accctgaagc cacccaccac cctggggctg ctgactgtgc tctgcagcct
      361 gttgctgtgg ggctccaggg atctgtaggc tctaggagag ccctactata gccctactgt
      421 gcagggatgt gc
//
