LOCUS       NM_198738               2079 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus phosphoserine aminotransferase 1 (Psat1), mRNA.
ACCESSION   NM_198738 XM_215179
VERSION     NM_198738.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2079)
  AUTHORS   Jia,L., Li,D., Wang,Y.N., Zhang,D. and Xu,X.
  TITLE     PSAT1 positively regulates the osteogenic lineage differentiation
            of periodontal ligament stem cells through the
            ATF4/PSAT1/Akt/GSK3beta/beta-catenin axis
  JOURNAL   J Transl Med 21 (1), 70 (2023)
   PUBMED   36732787
  REMARK    GeneRIF: PSAT1 positively regulates the osteogenic lineage
            differentiation of periodontal ligament stem cells through the
            ATF4/PSAT1/Akt/GSK3beta/beta-catenin axis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2079)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (bases 1 to 2079)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 2079)
  AUTHORS   Basurko,M.J., Marche,M., Darriet,M. and Cassaigne,A.
  TITLE     Phosphoserine aminotransferase, the second step-catalyzing enzyme
            for serine biosynthesis
  JOURNAL   IUBMB Life 48 (5), 525-529 (1999)
   PUBMED   10637769
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079352.1.
            
            On Mar 27, 2005 this sequence version replaced NM_198738.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079352.1, AY239016.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760396, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2079
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..2079
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /note="phosphoserine aminotransferase 1"
                     /db_xref="GeneID:293820"
                     /db_xref="RGD:735170"
     exon            1..77
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..1130
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /EC_number="2.6.1.52"
                     /codon_start=1
                     /product="phosphoserine aminotransferase"
                     /protein_id="NP_942033.2"
                     /db_xref="GeneID:293820"
                     /db_xref="RGD:735170"
                     /translation="MEATKQVVNFGPGPAKLPYSVLLEIQKQLLDYKGLGISVLEMSH
                     RSPDFAKIISNTENLVRELLVVPNNYKVIFVQGGGTGQFSAVPLNLIGLKAGRCADYV
                     VTGAWSAKAAEEAKKFGTVNIVHPKLGSYTKIPDPSTWNLNPDASYVYFCANETVHGV
                     EFDFIPDVKGAVLVCDMSSNFLSRPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLG
                     FALRECPSVLDYKVQAGNNSLYNTPPCFSIYVMDMVLEWIKNNGGAAAMEKLSSVKSQ
                     MIYEIIDNSQGFYVCPVERQNRSRMNIPFRIGNSKGDEALEKRFLDKAVELNMISLKG
                     HRSVGGIRASLYNAVTTEDVEKLAAFMKNFLEMHQL"
     exon            78..138
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /inference="alignment:Splign:2.1.0"
     exon            139..208
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /inference="alignment:Splign:2.1.0"
     exon            209..414
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /inference="alignment:Splign:2.1.0"
     exon            415..587
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /inference="alignment:Splign:2.1.0"
     exon            588..757
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /inference="alignment:Splign:2.1.0"
     exon            758..886
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1024
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..2053
                     /gene="Psat1"
                     /gene_synonym="Psa1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctgtcgcct tagcaccatg gaagccacca agcaagtggt taactttggg cccgggcctg
       61 ctaagctgcc gtactcggta ttgttagaga tacagaagca gctactggac tacaaaggac
      121 ttggcatcag tgtgcttgaa atgagtcaca ggtcaccaga tttcgccaag attattagca
      181 acacagagaa tcttgtgagg gaattgctag ttgttcccaa caactacaag gtgatctttg
      241 tacaaggagg tgggactggc cagttcagtg ccgtcccctt aaatctgatt ggcctgaaag
      301 ctggaaggtg tgccgactac gtggtgaccg gggcttggtc agctaaggct gcggaagaag
      361 ccaagaagtt tgggactgtg aacattgttc atcctaaact tggaagttac acaaaaattc
      421 cagacccaag cacctggaac ctcaacccgg acgcctccta cgtgtacttc tgtgcaaacg
      481 agactgtgca tggcgtggag tttgacttca tacctgacgt caagggagca gtgctggtct
      541 gtgacatgtc ctcaaacttc ttatccaggc cagtggacgt ttccaagttt ggtgtgattt
      601 tcgctggtgc tcagaagaat gttggctctg ctggggtgac ggtagtgatt gtccgtgatg
      661 acctgctggg gttcgccctc agagagtgcc catcagtcct tgactacaaa gtgcaggctg
      721 ggaacaactc tttgtataac acacctccat gcttcagcat ctacgtcatg gacatggtcc
      781 tggaatggat caagaacaat ggtggggccg cagccatgga gaagctcagc tccgtcaaat
      841 cccaaatgat ttatgagatt attgataatt ctcaaggatt ttatgtgtgt ccggtggagc
      901 gccagaatag aagcaggatg aacattccgt ttcgcattgg taacagcaaa ggggatgaag
      961 ctctggagaa gcgatttctt gacaaggccg tagaactcaa catgatctcc ttgaaggggc
     1021 acaggtcggt gggcggcatc cgagcgtctc tgtataatgc tgtcaccact gaagatgtgg
     1081 agaagttggc tgccttcatg aagaactttc tggagatgca tcagctgtga atgtgaccag
     1141 cctcaccccc gtgagcagcg ttcagagtaa ctcggggttt tctacagaaa cttaacagac
     1201 atggactctt tcacatacgt gctttttaca gatttctttt ttcaaagaat aaccactaag
     1261 ccacggggct ctgcagagcc gaggaaactc ccagctaacg gacaccttca ctcctactcg
     1321 gcctggaagc attttgaaag ctttcctgtt gcttttctaa tgaattcaac ctgtctgtca
     1381 tctttgctcc tttctctagg tgggttgaag gacttgcctt ggacttttcc ctgctggttc
     1441 caactggttc tttatcgtta ggagcgtatc ccaaggaggt tgagaggtcc tatgtgctgg
     1501 acggacagct gtgagtcggc caggttctgc agctgttggt taaagtcagc agtgactgat
     1561 gagcattctg gatctgtgta ctgcaattcc cataaaaaga caggcatgat aggccgtgtt
     1621 tatggagtgg gaactttttt aaacaccata cggtttatat ctatgctttt gaatttctaa
     1681 tgaaacagtt ctgtagaggc ttttcagagt tcgttcagcc cgtgactttg tgcatgaccg
     1741 tcgtctgttg tggacactgg caccctccac ctactgcctt ttaaagctgc ttcatgagaa
     1801 ggatctagga gttccatgat ttacttttct tgccacaagt agaagaaatg gttgtttctt
     1861 tgcttttcgg ttaggctgtt aaacaaaact cagttacacc cccaccccca aactgtgatc
     1921 gcatggctgt ttttgtagtt taaccagggc aatctgtaca ttccagatct ttgctgaggt
     1981 cttttctggt tgttcatgtg ttagtgtttt cgattgacga tatgaagaac attaaagtcc
     2041 tgagtcatct aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
