LOCUS       XP_017451624             424 aa            linear   ROD 22-FEB-2024
DEFINITION  probable threonine protease PRSS50 [Rattus norvegicus].
ACCESSION   XP_017451624
VERSION     XP_017451624.2
DBLINK      BioProject: PRJNA1074393
DBSOURCE    REFSEQ: accession XM_017596135.3
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086026) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XP_017451624.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Rattus norvegicus"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     Protein         1..424
                     /product="probable threonine protease PRSS50"
                     /calculated_mol_wt=46331
     Region          162..392
                     /region_name="Tryp_SPc"
                     /note="Trypsin-like serine protease; Many of these are
                     synthesized as inactive precursor zymogens that are
                     cleaved during limited proteolysis to generate their
                     active forms. Alignment contains also inactive enzymes
                     that have substitutions of the catalytic triad...;
                     cd00190"
                     /db_xref="CDD:238113"
     Site            order(192,245,349)
                     /site_type="active"
                     /db_xref="CDD:238113"
     CDS             1..424
                     /gene="Prss50"
                     /coded_by="XM_017596135.3:1402..2676"
                     /db_xref="GeneID:100910205"
                     /db_xref="RGD:6499372"
ORIGIN      
        1 mrrpmegaiv eepsgamepw cgagvrgqgp qgpgvpgasr trtraralll lllllllllp
       61 rrpagclaag espatlstav ptgprascas sgicpsgrlr lprqdqtsdt sqtttppkgm
      121 galstvgitg svsktkpgnl plcgssqepd ptlrdpeamt rrwpwmvsvq tngshvcagi
      181 liasqwvlav ahclsqnrvn ytvrvgspwi nqttetssdv pvnqviinsg yqskrywswv
      241 grihdigllk lkwglkysky vwpvclpgle yvvedgslct vtgwgypkan glwpqfqtlq
      301 ekevsilnsr ecehyyhkfs rihslvriis pqmicaldnd rekfcyersg eplvcssdgm
      361 wylvgvmswg pgckkseapp iflqvshyql wiwdrlsgep lalpapsrtl llgfllllil
      421 lgtl
//
