LOCUS       NM_199371               1621 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus protease, serine, 30 (Prss30), mRNA.
ACCESSION   NM_199371 XM_213243
VERSION     NM_199371.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1621)
  AUTHORS   Okumura,Y., Nishikawa,M., Cui,P., Shiota,M., Nakamura,Y.,
            Adachi,M., Kitamura,K., Tomita,K. and Kido,H.
  TITLE     Cloning and characterization of a transmembrane-type serine
            protease from rat kidney, a new sodium channel activator
  JOURNAL   Biol Chem 384 (10-11), 1483-1495 (2003)
   PUBMED   14669991
REFERENCE   2  (bases 1 to 1621)
  AUTHORS   Shaw-Smith,C.J., Coffey,A.J., Leversha,M., Freeman,T.C.,
            Bentley,D.R. and Walters,J.R.
  TITLE     Characterisation of a novel murine intestinal serine protease, DISP
  JOURNAL   Biochim Biophys Acta 1490 (1-2), 131-136 (2000)
   PUBMED   10786627
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Mar 29, 2021 this sequence version replaced NM_199371.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB073023.1, CK481701.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16093048, SAMN16418971
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-88                JAXUCZ010000010.1  13515518-13515605   c
            89-115              JAXUCZ010000010.1  13514544-13514570   c
            116-263             JAXUCZ010000010.1  13514265-13514412   c
            264-535             JAXUCZ010000010.1  13513903-13514174   c
            536-696             JAXUCZ010000010.1  13513011-13513171   c
            697-1621            JAXUCZ010000010.1  13511916-13512840   c
FEATURES             Location/Qualifiers
     source          1..1621
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..1621
                     /gene="Prss30"
                     /gene_synonym="Tmprss8; tmsp-1"
                     /note="protease, serine, 30"
                     /db_xref="GeneID:287106"
                     /db_xref="RGD:735142"
     exon            1..88
                     /gene="Prss30"
                     /gene_synonym="Tmprss8; tmsp-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..951
                     /gene="Prss30"
                     /gene_synonym="Tmprss8; tmsp-1"
                     /function="trypsin-like serine protease"
                     /note="transmembrane serine protease 8; serine protease
                     30; transmembrane serine protease 1; distal intestinal
                     serine protease; transmembrane protease, serine 8
                     (intestinal)"
                     /codon_start=1
                     /product="serine protease 30 precursor"
                     /protein_id="NP_955403.2"
                     /db_xref="GeneID:287106"
                     /db_xref="RGD:735142"
                     /translation="MESWARCIFLLLLQILTGGRGDILHSGAGKIVGGQDAPEGRWPW
                     QVSLRTEKEGHICGGSLIHEVWVLTAAHCFCRPLNSSFYHVKVGGLTLSLTEPHSTLV
                     AVRNIFVYPTYLWEDASSGDIALLRLDTPLQPSQFSPVCLPQAQAPLTPGTVCWVTGW
                     GATHERELASVLQELAVPLLDSEDCERMYHIGETSLSGKRVIQSDMLCAGFVEGQKDS
                     CQGDSGGPLVCAINSSWIQVGITSWGIGCARPNKPGVYTRVPDYVDWIQRTLAENHSD
                     AYGCRSRASGAYPALLLVLLAFALPESL"
     exon            89..115
                     /gene="Prss30"
                     /gene_synonym="Tmprss8; tmsp-1"
                     /inference="alignment:Splign:2.1.0"
     exon            116..263
                     /gene="Prss30"
                     /gene_synonym="Tmprss8; tmsp-1"
                     /inference="alignment:Splign:2.1.0"
     exon            264..535
                     /gene="Prss30"
                     /gene_synonym="Tmprss8; tmsp-1"
                     /inference="alignment:Splign:2.1.0"
     exon            536..696
                     /gene="Prss30"
                     /gene_synonym="Tmprss8; tmsp-1"
                     /inference="alignment:Splign:2.1.0"
     exon            697..1621
                     /gene="Prss30"
                     /gene_synonym="Tmprss8; tmsp-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctgacccc actgtgccgt ggaccagaga ggagccatgg agtcctgggc aaggtgcatt
       61 tttcttctct tgctgcagat cctgacaggg ggacgtggag atatattgca ttcaggtgct
      121 gggaagattg tgggtggcca agatgccccg gaaggacgat ggccttggca agtcagcctg
      181 aggacagaga aagagggcca catatgcggg ggctccctca ttcacgaggt gtgggtgctc
      241 acggctgccc actgcttctg caggcctctg aactccagtt tctaccacgt gaaggttgga
      301 ggactgacac tttctcttac ggaaccccac tcaaccttag tggccgtgag gaacatcttt
      361 gtgtatccca cctacctctg ggaagatgcg tctagcggag acattgctct gctgcggctg
      421 gacactcctc tgcagccctc tcagttctct cctgtctgcc tcccacaagc ccaggctcct
      481 ctcacccctg ggactgtctg ctgggtaaca ggctgggggg ctacccacga aagagagctg
      541 gcgagtgtcc tccaggagtt agctgtgcct ctcttggact cagaggactg tgaaaggatg
      601 taccacatcg gggagaccag cctgtcaggg aagagagtca tccagtcaga catgctctgt
      661 gccggctttg tagaaggcca gaaagactcc tgccagggtg actctggggg cccactcgtc
      721 tgtgccatca atagttcttg gatccaggtt gggatcacca gctggggtat tggctgtgct
      781 cggccaaaca agcctggtgt ctatactcgg gtgccagact acgtagactg gattcagaga
      841 accctggcgg agaaccactc tgatgcctac ggatgccgct ccagagcctc tggggcatat
      901 ccagcactgc tgctggtgtt gctggcattt gccttgccag agtccctgtg aatcgtgagc
      961 tctagagttc tggatcctct tctgctgggc ttggagactc aggagctcaa aatagacact
     1021 gagaaaatga acctggaatg gaggtcttgc aggtgtcagc ctgggaggtt tggaggccgc
     1081 agtgactcac agagcttaag gacatagtaa ttcggaccac agggacacat cctatcaaag
     1141 tcaagcagcc acctacatgt cacttaacac aggcctggtc acgtgtcagc tctacttgga
     1201 ccaactcttt ttttggtcac acaacagtgc tgcagtgggg aagtagagat actcagagag
     1261 ggcatgcgag cttcctaagg tcacacagct agctgctagg gtagaatctc tattaaacag
     1321 gcatggatgg tctatgctct agcctagagg gaagcctcac tgtatggccc atgctggcct
     1381 cagcctccca aatgtatctt ttaaagacac gcatcaccac acttggcttc tgttcttcac
     1441 tcataacgca ccattgttct gggagaaaag aattcctttg acatggaacc ggaaaggtgg
     1501 cctagcaatt aagagacttc cagagcacca gcgcttacag cggcaggagg tcctctgagg
     1561 tcatacacac atgattcgca aacactcgca caattaaaaa taaactaatt tttataaaga
     1621 t
//
