LOCUS       NM_182949               1154 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Rattus norvegicus serine protease 27 (Prss27), mRNA.
ACCESSION   NM_182949
VERSION     NM_182949.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1154)
  AUTHORS   Adachi,W., Ulanovsky,H., Li,Y., Norman,B., Davis,J. and
            Piatigorsky,J.
  TITLE     Serial analysis of gene expression (SAGE) in the rat limbal and
            central corneal epithelium
  JOURNAL   Invest Ophthalmol Vis Sci 47 (9), 3801-3810 (2006)
   PUBMED   16936091
REFERENCE   2  (bases 1 to 1154)
  AUTHORS   Wong,G.W. and Stevens,R.L.
  TITLE     Identification of a subgroup of
            glycosylphosphatidylinositol-anchored tryptases
  JOURNAL   Biochem Biophys Res Commun 336 (2), 579-584 (2005)
   PUBMED   16143303
REFERENCE   3  (bases 1 to 1154)
  AUTHORS   Puente,X.S. and Lopez-Otin,C.
  TITLE     A genomic analysis of rat proteases and protease inhibitors
  JOURNAL   Genome Res 14 (4), 609-622 (2004)
   PUBMED   15060002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB101677.1.
            
            On Jan 9, 2008 this sequence version replaced NM_182949.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB101677.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMD00132276,
                                           SAMEA5760389 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1154
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..1154
                     /gene="Prss27"
                     /gene_synonym="Mpn"
                     /note="serine protease 27"
                     /db_xref="GeneID:287108"
                     /db_xref="RGD:1303256"
     exon            1..119
                     /gene="Prss27"
                     /gene_synonym="Mpn"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..1051
                     /gene="Prss27"
                     /gene_synonym="Mpn"
                     /note="pancreasin; marapsin; protease, serine 27"
                     /codon_start=1
                     /product="serine protease 27 precursor"
                     /protein_id="NP_891994.3"
                     /db_xref="GeneID:287108"
                     /db_xref="RGD:1303256"
                     /translation="MRQPHITALLLLPLLLRSGTEGAEAMRACGHPRMFNRMVGGEDA
                     LEGEWPWQVSIQRNGAHFCGGSLIAPTWVLTAAHCFSNTSDISIYQVLLGALKLQQPG
                     PHALYVPVKRVKSHPEYQGMASSADVALVELQVPVTFTKYILPVCLPDPSVVFKSGMN
                     CWVTGWGSPSEQDRLPNPRILQKLAVPLIDTPKCNLLYSKDAEADIQLKTIKDDMLCA
                     GFAEGKKDACKGDSGGPLVCLVDQSWVQAGVISWGEGCARRNRPGVYIRVASHYQWIH
                     QIIPELQFQGRAGSQQQQRDPRGWQPLAENSAPCLAAHAVLLALGALMLGIL"
     exon            120..146
                     /gene="Prss27"
                     /gene_synonym="Mpn"
                     /inference="alignment:Splign:2.1.0"
     exon            147..309
                     /gene="Prss27"
                     /gene_synonym="Mpn"
                     /inference="alignment:Splign:2.1.0"
     exon            310..581
                     /gene="Prss27"
                     /gene_synonym="Mpn"
                     /inference="alignment:Splign:2.1.0"
     exon            582..751
                     /gene="Prss27"
                     /gene_synonym="Mpn"
                     /inference="alignment:Splign:2.1.0"
     exon            752..1154
                     /gene="Prss27"
                     /gene_synonym="Mpn"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtagcactag ggagagcttc tgtcactgct gaccaggact caaacggcca ccaaaccaga
       61 gaccatgagg cagccccaca tcactgccct gctgctgttg ccgctgctgc tgagatctgg
      121 gactgaaggg gccgaggcta tgagagcctg tgggcatcca aggatgttta accggatggt
      181 gggcggggag gatgccttag aaggtgagtg gccctggcag gtcagcatcc agcgcaatgg
      241 agctcacttc tgtgggggca gcctcatcgc accaacatgg gtcctcactg ctgctcactg
      301 cttctccaac acatcagaca tatccatata ccaggtcctg ctgggggcac tgaagctgca
      361 acagccagga ccacatgccc tgtatgtccc cgtgaagcgg gtgaaaagcc atcctgagta
      421 ccaaggcatg gcttccagtg ccgacgtggc tctggtggag ctgcaggtgc ctgtgacctt
      481 caccaaatac atccttcccg tgtgcctgcc tgacccttcg gtcgttttca agtcgggcat
      541 gaactgctgg gtcaccggct ggggcagtcc cagtgagcaa gaccggctac ccaacccacg
      601 gatcctgcag aaacttgctg tgcctctcat tgacacgccc aagtgcaacc ttctgtacag
      661 caaggatgct gaggctgaca tccagctcaa aaccatcaag gacgacatgc tctgtgcagg
      721 ctttgcagag ggcaagaagg acgcctgtaa gggtgactct ggaggcccat tggtatgcct
      781 tgtggaccag tcatgggtgc aggctggggt aatcagctgg ggagagggct gtgcccgccg
      841 gaatcgtcca ggtgtctaca tccgtgtggc ttctcattac caatggatcc accaaatcat
      901 cccagaacta cagttccagg ggagagccgg cagccagcag cagcaaagag acccccgagg
      961 ttggcagccc ctggcagaga actccgcccc ctgcctggct gcccatgcag ttttgctggc
     1021 cctgggagca ctgatgcttg ggatcctcta gggctgctca gcccggcagg tggagcccca
     1081 cccactgtac atttgtaaat actgtccccc tatcttacat cccagccact tttatttatg
     1141 ttcacctcca gaaa
//
