LOCUS       NM_001032285            1954 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus proline-rich transmembrane protein 1 (Prrt1),
            mRNA.
ACCESSION   NM_001032285 XM_001060070
VERSION     NM_001032285.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1954)
  AUTHORS   Matt,L., Kirk,L.M., Chenaux,G., Speca,D.J., Puhger,K.R.,
            Pride,M.C., Qneibi,M., Haham,T., Plambeck,K.E., Stern-Bach,Y.,
            Silverman,J.L., Crawley,J.N., Hell,J.W. and Diaz,E.
  TITLE     SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and
            Plasticity Underlying Cognitive Function
  JOURNAL   Cell Rep 22 (9), 2246-2253 (2018)
   PUBMED   29490264
REFERENCE   2  (bases 1 to 1954)
  AUTHORS   Kirk,L.M., Ti,S.W., Bishop,H.I., Orozco-Llamas,M., Pham,M.,
            Trimmer,J.S. and Diaz,E.
  TITLE     Distribution of the SynDIG4/proline-rich transmembrane protein 1 in
            rat brain
  JOURNAL   J Comp Neurol 524 (11), 2266-2280 (2016)
   PUBMED   26660156
  REMARK    GeneRIF: These results indicate that, although SynDIG4 shares
            sequence similarity with SynDIG1, it might act through a unique
            mechanism as an auxiliary factor for extrasynaptic GluA1-containing
            AMPA receptors
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Dec 29, 2021 this sequence version replaced NM_001032285.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643285.54710.1,
                                           SRR26643298.77629.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840107,
                                           SAMN12840108 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               JAXUCZ010000020.1  4126069-4126213     c
            146-684             JAXUCZ010000020.1  4124571-4125109     c
            685-870             JAXUCZ010000020.1  4123790-4123975     c
            871-1954            JAXUCZ010000020.1  4122565-4123648     c
FEATURES             Location/Qualifiers
     source          1..1954
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1954
                     /gene="Prrt1"
                     /gene_synonym="DSPD1; Ng5; Orf31; SynDIG4"
                     /note="proline-rich transmembrane protein 1"
                     /db_xref="GeneID:406167"
                     /db_xref="RGD:1359348"
     exon            1..145
                     /gene="Prrt1"
                     /gene_synonym="DSPD1; Ng5; Orf31; SynDIG4"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..1047
                     /gene="Prrt1"
                     /gene_synonym="DSPD1; Ng5; Orf31; SynDIG4"
                     /note="dispanin subfamily D member 1; synapse
                     differentiation-induced protein 4"
                     /codon_start=1
                     /product="proline-rich transmembrane protein 1"
                     /protein_id="NP_001027456.1"
                     /db_xref="GeneID:406167"
                     /db_xref="RGD:1359348"
                     /translation="MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPIPPPQTAPSSHHHH
                     HHHYHQSGTATLPRLGAGGLASAAAGAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCA
                     TLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAPTAQAPGFVVPTHAGAVGTLPL
                     GGYVAPGYPLQLQPCTAYVPVYPVGTPYASGTPGGPGVTSTLPPPPQGPGLALLEPRR
                     PPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISL
                     AVGIAAMVLCTILTVVIIIAAQHHENYWDP"
     exon            146..684
                     /gene="Prrt1"
                     /gene_synonym="DSPD1; Ng5; Orf31; SynDIG4"
                     /inference="alignment:Splign:2.1.0"
     exon            685..870
                     /gene="Prrt1"
                     /gene_synonym="DSPD1; Ng5; Orf31; SynDIG4"
                     /inference="alignment:Splign:2.1.0"
     exon            871..1954
                     /gene="Prrt1"
                     /gene_synonym="DSPD1; Ng5; Orf31; SynDIG4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atttcctcgc tgctgctgct gctaccgccg ctgcaccggc tgcgccatcc gggactcaga
       61 ctcctgcgcc agcagtcagg gggccctgac tctagcttca gagaccctgt tccagcgctt
      121 gcgagcatgt cgtcagaaaa gtcaggcctt ccagactcgg ttccccacac ttcacctccg
      181 ccctacaatg ccccccaacc tccagccgag ccccccatcc ctcccccaca aaccgctcca
      241 tcctctcatc atcatcacca ccaccactac caccagtctg gcactgccac cctcccgcgc
      301 ttaggagcag gtggcctggc ctctgctgcg gctggcgctc aacgtggtcc ttcgtcctct
      361 gccacgctac cgcggccccc ccaccatgcc cctcccggtc ccgctgctgg ggctccccca
      421 cccggctgtg ctaccctacc ccgcatgcca cccgaccctt atctgcagga gactcgcttc
      481 gagggtccac ttcccccacc accgcctgcg gccgccgccc cacccccacc agcgcctgcc
      541 ccgacggccc aagccccagg cttcgtggtg cccacgcacg cgggggcggt gggcacgttg
      601 ccgctggggg gctacgtggc tccgggctac ccgctgcagc tgcagccgtg caccgcttat
      661 gtcccggtgt atccggtggg cacgccctac gcaagcggga cccccggggg tccaggagtg
      721 acctccactc tgcccccgcc gccccagggc ccagggttgg ctctgttgga gcccaggcgc
      781 ccgccgcatg actacatgcc catcgctgtg ctgaccacca tctgctgctt ctggcccaca
      841 ggcatcatcg ccatcttcaa ggccgtgcag gtgcgcacgg ccttggcccg cggagacttg
      901 gtgtccgccg agatcgcttc gcgcgaggcc cggaatttct ccttcatctc cctggccgtg
      961 ggcatcgcag ctatggtgct ttgtaccatc ctcactgtag tcatcatcat tgccgcccag
     1021 caccacgaaa actactggga tccctaaaaa cgtccccgtc tcggccccgc tccgtgcccc
     1081 ctcccaacct cccaggcgcg tggcgcagtc ctgccgccta cccagagcgc gccctgcaca
     1141 tcctcctgag gcgccgctgg acttccagac atcataaact ccgcccccac ggaacctctg
     1201 gcccagagag tacgctcagt tcctcaggaa cccctctagc acccacatcc tcagcggcac
     1261 tggaatccgc gccaaacccc gaccctccag tcgccccaat tccccacccc atcaaagtgc
     1321 agtgccagcc aggggcggat ctctcctgct ctccgctccc cagtagggag tcaggtccca
     1381 gaagctccgc ctcatctata agctccgccc caaatcccac aaaccccgcc tccaggtcgg
     1441 caggctccgc cttcttttct tctttggggt ttttcagtct ggtgattggg tctgtgaatc
     1501 caggccccca gcccacaata cagacggact agtcccccta cctccctaaa aggactcagc
     1561 cctgggagaa ctacaccccc actctagctc ggatttttgc cagtgcggat ttttctcccc
     1621 gcccccaacc cccatctctg cctattttct tgctaattac agaacttccc attttgcggc
     1681 ttttggagtg agatgaggca agttccaggt ttagtacccc tcactctgga aagagaacca
     1741 agtccctata atgtaaatac cctttctaca tgtgccaacc cctgggcagc gggggcagaa
     1801 gagaatccag ggttaaaggg agggagtcga cgctcccccg ctcccctctg ccctagactt
     1861 gttttgatct gtgtgtgcca gtgtgtgtga acttctgaaa gacagtatta aagacatttt
     1921 agtggattta tcacccgcag ttccaaagac caca
//
