LOCUS       NM_001371270           10616 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus proline-rich coiled-coil 2B (Prrc2b), transcript
            variant 1, mRNA.
ACCESSION   NM_001371270 XM_006224346 XM_008761783
VERSION     NM_001371270.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 10616)
  AUTHORS   Wilson R, Geyer SH, Reissig L, Rose J, Szumska D, Hardman E, Prin
            F, McGuire C, Ramirez-Solis R, White J, Galli A, Tudor C, Tuck E,
            Mazzeo CI, Smith JC, Robertson E, Adams DJ, Mohun T and Weninger
            WJ.
  TITLE     Highly variable penetrance of abnormal phenotypes in embryonic
            lethal knockout mice
  JOURNAL   Wellcome Open Res 1, 1 (2017)
   PUBMED   27996060
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10616)
  AUTHORS   Mei,Q., Liu,J., Liu,Y., Li,C., Wang,H., Li,H., Chen,X. and Lan,X.
  TITLE     Expression of proline-rich coiled-coil 2B protein in developing rat
            brains
  JOURNAL   Neurosci Lett 557 Pt B, 171-176 (2013)
   PUBMED   24466597
  REMARK    GeneRIF: findings comprehensively revealed the expression pattern
            of PRRC2B protein in the whole rat brain at various stages for the
            first time
REFERENCE   3  (bases 1 to 10616)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 10616)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000115.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001371270.3.
            
            On Feb 10, 2021 this sequence version replaced NM_001371270.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-170               JACYVU010000115.1  8922120-8922289
            171-348             JACYVU010000115.1  8922807-8922984
            349-451             JACYVU010000115.1  8925124-8925226
            452-524             JACYVU010000115.1  8927038-8927110
            525-668             JACYVU010000115.1  8931069-8931212
            669-910             JACYVU010000115.1  8933310-8933551
            911-1032            JACYVU010000115.1  8933928-8934049
            1033-1172           JACYVU010000115.1  8934418-8934557
            1173-1263           JACYVU010000115.1  8938775-8938865
            1264-1456           JACYVU010000115.1  8940889-8941081
            1457-1772           JACYVU010000115.1  8944986-8945301
            1773-2041           JACYVU010000115.1  8947207-8947475
            2042-2237           JACYVU010000115.1  8949608-8949803
            2238-2454           JACYVU010000115.1  8953775-8953991
            2455-4521           JACYVU010000115.1  8954548-8956614
            4522-4709           JACYVU010000115.1  8957773-8957960
            4710-4855           JACYVU010000115.1  8958343-8958488
            4856-4991           JACYVU010000115.1  8958930-8959065
            4992-5074           JACYVU010000115.1  8960464-8960546
            5075-5263           JACYVU010000115.1  8961036-8961224
            5264-5461           JACYVU010000115.1  8961334-8961531
            5462-5548           JACYVU010000115.1  8961858-8961944
            5549-5653           JACYVU010000115.1  8962822-8962926
            5654-5846           JACYVU010000115.1  8963100-8963292
            5847-5944           JACYVU010000115.1  8963990-8964087
            5945-6072           JACYVU010000115.1  8965179-8965306
            6073-6313           JACYVU010000115.1  8965711-8965951
            6314-6469           JACYVU010000115.1  8967879-8968034
            6470-6561           JACYVU010000115.1  8968637-8968728
            6562-6643           JACYVU010000115.1  8970654-8970735
            6644-10616          JACYVU010000115.1  8971954-8975926
FEATURES             Location/Qualifiers
     source          1..10616
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..10616
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /note="proline-rich coiled-coil 2B"
                     /db_xref="GeneID:296637"
                     /db_xref="RGD:1595906"
     exon            1..170
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..6775
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein BAT2-like 1"
                     /codon_start=1
                     /product="protein PRRC2B isoform 1"
                     /protein_id="NP_001358199.1"
                     /db_xref="GeneID:296637"
                     /db_xref="RGD:1595906"
                     /translation="MSDRLGQITQGKDGKSKYSTLSLFDKYKGRSVGAVRSSVIPRHG
                     LQSLGKVATARRMPPPANLPSLKSENKGNDPNIVIVPKDGTGWANKQDQQDPKSSSVT
                     ASQLPESQPQPGLQKSVSNLQKPTQSISQENTSSVPGGPKSWAQLSGKPVGHEGGLRG
                     SSRLLSFSPEEFPTLKAAGGQDKAGKEKGALDLSYGPGPSLRPQNVSSWREGGGRNII
                     SAVSLSASPTELGSRNSSGGDGASSSACTSDSKDPSLRPAQPSRKGASQFMGHVYQPP
                     TYHDMLPAFMCSPQSSENQNTVERSSFPLPQLRLEPRVPFRQFQMNDQDGKERPGVAR
                     PVRPLRQLVERAPRPTIINAENLKGLDDLDTDADDGWAGLHEEVDYSEKLKFSDDEDE
                     EDVVKDGRSKWNNWDPRRQRALSLSSADSTDAKRTQEEGKDWSGTAGVSRVVRKVPEP
                     QPPSRKLHSWASGPDYQKPTMGSMFRPQSIEDKEDKPPPRQKFIQSEMSEAVERARKR
                     REEEERRAREERLAACAAKLKQLDQKCRQAQKASETPKPVEKEVPRSPGIEKLSPPEN
                     GPVVRKGSPEFPVQEAPTMFLEETPATSPTVAQSNNSSSSSSSSIEEEVREAGSPAQE
                     FSKYQKSLPPRFQRQQQQQQQQQQQQQQQQQQQQQQQQEQLYKMQHWQPVYPPPSHPQ
                     RTFYPHHPQMLGFDPRWMMMPSYMDPRITPTRTPVDFYPSALHPSGLMKPMMPQESLS
                     GTGCRSEDQNCVPSLQERKVTAIDPAPVWSPEGYMALQNKGYSLSHPKSADTLAMGMH
                     VRNERSYCASPGRSGGISAQRDLFEERGEEFLSAFDKKAQADFDSCISSQRIGQELLF
                     PPQENVQEVGAPGGCTPNLRCSPLEPDFVPAEKKPECGSWDVGHQPKAADMANSVELE
                     APRQEPSFHVSSWEKEGSPKKQPNPEPEWTPEPRSSSGQQQEQPGRTRRSGPIKKPVL
                     KALKVEEKEKALERVRQGLGEESSQRATEKEPPCRAEEDEDEENNPALANASSALEDK
                     AAARGGFGHEASKLDEEAKTDKTWESRPSREASEIPPPKRNNWIFIDEEQAFGGRAQA
                     RSRGRGFREFTFRGGRPTSSSTSGLCGTGVLGSRGMYSGGQRSNRGRGLRDFPPPEDC
                     PRAKPRRRIASETHSEGSEYEELPKRRRQRGSEPSHEGMLTERDEGALKDSWRSNRTY
                     TEDQGSLDARSRGPRTCGRALPPRLSNCSYGRRTFVAKEPPHWQSRSPGNSWQEYGSS
                     DPCGPRRATDRDYIPDSYRHSDTFGSRLFEDSRTEDKKSFFQDDHGADSEGAENRPFR
                     RRRPPRQDKPPRFRRLRQERESLGLWGPEEESHLLASQWPGRSKLCPGDKSGPGGHRS
                     PELSYQNSSDHANEEWETASESSDFSERRERREGLAAEPEAQGDGGLSGASLGEKKEL
                     AKRSFSSQRPLADRQSRKLEPGGFGEKPVRPGGGETSPRCESQQSGTPLKVKRSPDEA
                     LPGGLGSHSPYALERTTHGSSDGSETTSKKTEKEVSLAAQRAGEQEEARKQFDLGYGN
                     AIIDNCGSSPGEENEVGSMVGEGFIEVLTKKQRRLLEEERRKKEQAAQVKGRGLSSRI
                     PPRFAKKQNGLCLEQGDVAVPGSSLGTEIWESSSQALPVQGAASDSWRTAVTAFSSAE
                     PGTSEGFKSSQGDSGVDLSAESRESSATSSQRSSPYGTLKPDEMSGPGLAESKADSHK
                     DQAQKQSEHKDSEQGSGQSKEHRPGPIGNERSLKNRKGSEGAERLQGAVVPPVNGVEI
                     HVDSVLPVPPIEFGVSPKDSDFSLPPGSVSGPVGNPVAKLQDVLASNAGLTQSIPILR
                     RDHHIQRAIGLSPMSFPTADLTLKMESARKAWENSPSLPEQNSPGGAGSGIQPPSSVG
                     ASNGVNYSSFGGVSIPPMPVASVAPSASMPGSHLPPLYLDGHVFASQPRLVPQTIPQQ
                     QSYQQAATAQQIPISLHTSLQAQAQLGLRGGLPASQSQEIFSSLQPFRSQVYMHPSLS
                     PPSTMILSGGTALKPPYSAFPGIQPLEMVKPQSGSPYQPMSGNQALVYEGQLGQAAGL
                     GASQMLDSQLPQLTMPLPRYGSGQQPLILPQSIQLPPGQSLSVGAPRRIPPPGSQPPV
                     LNTSRESTQMELKGFHFADNKQNVSTGGSAPSPQAYRPSSASPSGKPSGSAVNMGSVQ
                     GHYVQQAKRVDEKPSLGTVKLQEASSATSQMKRTGAIKPRAVKVEGSKA"
     exon            171..348
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            349..451
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            452..524
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            525..668
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            669..910
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1032
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1172
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1263
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1456
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1457..1772
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1773..2041
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            2042..2237
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2454
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            2455..4521
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            4522..4709
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            4710..4855
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            4856..4991
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            4992..5074
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            5075..5263
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            5264..5461
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            5462..5548
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            5549..5653
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            5654..5846
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            5847..5944
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            5945..6072
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            6073..6313
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            6314..6469
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            6470..6561
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            6562..6643
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
     exon            6644..10616
                     /gene="Prrc2b"
                     /gene_synonym="Bat2l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaaatcggg agcggtgccg agaaaaattt ccttactaga tgacatttca tcgcaatgtc
       61 cgatcgtttg gggcaaataa cccagggcaa ggatgggaaa agcaagtact cgactctcag
      121 cctgtttgac aagtataaag ggaggtcagt aggcgcagtc agatcctcag ttattcctag
      181 acatggctta cagagtctcg ggaaagttgc cacagcccgg cgtatgccac cgcctgcaaa
      241 cctgccaagc ctgaagtctg aaaacaaagg aaacgacccc aacatcgtga tagttcccaa
      301 ggacgggaca ggatgggcca acaagcagga ccagcaagac ccaaagagtt ccagtgtgac
      361 agcctctcag ctgccggagt cgcagccgca gccgggtttg cagaaatctg tctccaactt
      421 gcagaaaccg acacagtcta tcagtcagga gaacacaagt tcagtgccag gtggaccaaa
      481 gtcatgggca cagctgagtg gaaagccagt cggacacgaa ggtggtttaa ggggctcaag
      541 ccgactgtta tccttctctc ccgaggaatt tccgacgctg aaagcagctg gcgggcagga
      601 caaggctggc aaagaaaagg gcgccttaga tctgtcgtat gggccaggac caagcctccg
      661 ccctcagaat gtgtcaagct ggagggaggg cggtgggcga aacatcatct ctgccgtgtc
      721 tctgagtgcc tccccaacag agctgggcag cagaaactcc agtgggggag atggagcctc
      781 ctcctcggca tgcaccagcg attctaagga cccctctctc cgcccggctc agcccagccg
      841 caaaggggcg tcacagttca tgggacatgt ttaccagccg cccacatacc atgacatgct
      901 tccagctttt atgtgttcac cacagtcatc cgagaaccag aatacggtgg aacgaagctc
      961 attccccctt cctcagctcc gcctggaacc ccgtgttcct ttcagacagt tccagatgaa
     1021 tgaccaagat gggaaagaaa gaccaggcgt ggcaaggcct gtgcgcccac tcaggcagct
     1081 ggtggagcgg gcaccacggc ccaccatcat caacgcagaa aatctgaagg gcctggatga
     1141 tctggacacc gacgcagatg atggctgggc aggcctccac gaggaagtgg actattctga
     1201 gaaactcaag ttcagtgacg atgaggatga ggaggacgtc gtgaaagatg gccggtcaaa
     1261 gtggaacaat tgggacccca ggcgtcagag agcattgtcg ctgagctctg cagacagcac
     1321 cgatgccaag cgcactcagg aggaaggaaa agactggagt ggaacagcag gtgtgtcccg
     1381 tgtcgtccga aaggtgccag agcctcagcc tccttccagg aagcttcaca gctgggcctc
     1441 aggccccgac taccagaagc ccacaatggg cagcatgttc cgcccacagt ccatcgagga
     1501 caaggaggac aagccacccc cacggcagaa gttcatccag tcagagatgt ccgaggccgt
     1561 ggaacgagcc cgaaagcgca gggaagaaga ggagcgccgg gcccgggagg aaaggctagc
     1621 tgcctgtgct gccaaactca agcagctaga ccagaagtgc aggcaggctc agaaggccag
     1681 tgagacaccg aaaccagtgg aaaaggaggt cccccgatcc ccgggcattg agaagctctc
     1741 cccaccagag aacggccctg ttgtccgtaa aggctcccca gaattccctg tgcaagaagc
     1801 acccaccatg ttcttggaag agacacctgc aacgtcccca acagtggctc agagcaacaa
     1861 cagcagcagc agcagcagta gcagcatcga ggaggaagtc cgggaggctg ggtcccctgc
     1921 acaggagttc agcaagtacc agaagtccct tcctccccgt ttccagcgcc agcaacagca
     1981 gcagcagcag cagcaacaac aacagcagca gcagcagcaa cagcaacagc agcaacagca
     2041 ggagcagctg tacaagatgc aacactggca gccggtgtac cccccacctt ctcaccccca
     2101 gcgtaccttc tacccacacc acccccagat gctgggcttt gacccacggt ggatgatgat
     2161 gccctcctac atggacccgc gcatcacccc gacgcgcaca cccgtggact tctacccctc
     2221 agccctgcat ccttcaggac tgatgaaacc catgatgccc caagagtccc tcagtgggac
     2281 tggctgtcgc tctgaagatc aaaactgtgt gccctcactc caagaacgaa aagtgaccgc
     2341 catcgacccg gctcctgtgt ggagcccaga gggctacatg gcactgcaga acaagggcta
     2401 ctcactgtcc cacccgaagt ctgccgacac tctggccatg ggcatgcacg tcaggaatga
     2461 aaggtcttac tgtgcctccc ccggaaggtc agggggcata agtgcccagc gcgatctctt
     2521 tgaggagaga ggggaggagt tcttgagtgc ttttgacaag aaggcccaag cagactttga
     2581 cagctgtatc tcttctcaaa gaataggcca ggagctttta tttccacccc aggaaaatgt
     2641 tcaggaggtg ggtgctcctg ggggttgtac cccaaacctc aggtgttccc cattggagcc
     2701 tgactttgtc ccggctgaga aaaagccaga gtgtggcagc tgggatgttg gccaccagcc
     2761 aaaggctgcc gacatggcca acagtgtcga gctggaggcg ccccggcagg agccttcctt
     2821 tcatgtttcc tcttgggaga aggaagggag ccccaagaaa cagccaaacc cagagcccga
     2881 gtggacaccc gagccccgga gctccagcgg ccagcagcag gagcagcccg gcaggacccg
     2941 gaggtcaggg cccatcaaga aacctgttct caaggccctg aaggtggaag aaaaggagaa
     3001 agccctggag agagtcaggc agggccttgg agaggagagc tcacagaggg ccacagagaa
     3061 agaacccccg tgcagggcgg aagaggacga ggatgaggag aacaaccctg ccctagccaa
     3121 cgcctcctcg gccctggagg ataaggctgc tgcccggggt gggtttggcc atgaggctag
     3181 caagctggat gaagaagcaa agactgacaa gacctgggag agcaggccct caagggaggc
     3241 cagtgagatt ccgccaccca agagaaacaa ctggatcttc attgatgagg agcaggcctt
     3301 tgggggccgg gcccaggccc gtagccgtgg ccgtggtttc agagagttca ccttccgggg
     3361 cggccggcct acaagcagca gtacaagtgg tctttgtggc acaggcgtcc tcgggtctcg
     3421 tggcatgtac agtggtggcc agcgcagtaa ccgaggcagg ggcctgcgtg acttcccccc
     3481 accagaagac tgccccagag ccaagccaag acggcgcatt gccagcgaga cccacagcga
     3541 gggctccgag tacgaagagc tacccaagag gcgccggcag cggggctcag agcccagcca
     3601 cgagggcatg ctcacagaga gggacgaggg cgccctgaag gactcatggc gctccaacag
     3661 gacttacaca gaggaccagg gtagtctaga cgcccgcagc cggggacccc ggacatgcgg
     3721 gagagccctc ccacctcgcc tgagcaactg cagctatggc cgcagaacct ttgttgccaa
     3781 agaacctccc cactggcaga gcaggagccc aggcaactcc tggcaggaat atggctcctc
     3841 tgacccgtgt ggcccacggc gagccactga cagagactac ataccagact cctaccgaca
     3901 ctctgacaca tttggcagca ggctttttga ggacagccgc acggaggaca agaagtcctt
     3961 tttccaagat gaccacgggg cagattctga aggtgcagaa aacaggccct tccgtcggag
     4021 gcggccacca cgtcaagaca agccccctcg cttccggcgc ctccgtcaag agcgagagtc
     4081 cctaggcctg tggggacctg aagaagagtc ccatctgctg gcaagccagt ggccaggccg
     4141 gtccaaactc tgtcctgggg acaagagtgg tcctggaggt cacagatccc cagagctttc
     4201 ctaccagaat tcttctgatc acgccaatga agagtgggag accgcctccg agagtagcga
     4261 cttcagcgag cgtagggagc ggcgagaagg cctcgcagct gaacctgaag cacaagggga
     4321 tggtggcctc tctggggcca gtctgggtga aaagaaagag ctggccaaga ggagcttctc
     4381 cagccagagg cccctggctg acagacagag ccgcaagctg gagccgggag ggtttgggga
     4441 gaagcctgtt aggccaggtg ggggtgagac ttccccccgc tgcgagagcc agcagagtgg
     4501 gacgcctctg aaagtcaaaa ggtctccaga tgaggccttg cctggaggcc ttggaagcca
     4561 ttcaccctat gccttggaga ggaccactca tggcagctct gacggttctg aaactaccag
     4621 taagaaaaca gagaaagagg tttctttggc tgcccagagg gctggtgagc aggaagaggc
     4681 ccggaagcag tttgacctgg gctatggaaa tgctatcatt gacaactgtg gttccagccc
     4741 tggggaagag aatgaagtag gctccatggt gggcgaaggc ttcatcgaag tcctgaccaa
     4801 gaagcagcgc cgcctgctgg aggaggagag aaggaaaaaa gaacaggctg ctcaggtcaa
     4861 aggtcgaggc ctttcctcac ggattcctcc tcgctttgct aaaaagcaga atggcctgtg
     4921 tctggagcaa ggagacgtgg ccgtgcctgg cagcagcctg ggcactgaga tctgggagag
     4981 cagcagccaa gccctccctg tgcagggcgc cgccagcgac tcttggagga cagctgtcac
     5041 tgccttcagc agtgctgagc ctggcacctc agagggtttt aagagcagcc agggagatag
     5101 tggtgttgac ttgagcgcgg agtctcggga gtcgtctgcg acctcctcac agcgcagttc
     5161 cccttatggt actctcaagc cagatgagat gagtgggcct ggcctggcgg aatccaaggc
     5221 cgacagccac aaggaccaag ctcagaagca gtctgagcac aaggactcag aacaaggctc
     5281 tggacagagc aaggaacaca gaccaggacc catcggcaat gagcggtctc tgaaaaacag
     5341 aaagggctcg gaaggggccg agcggctaca aggggccgtc gtcccgcctg ttaatggggt
     5401 agagattcat gtggactccg tgctgcctgt gccgcccatc gagtttggag tcagtccaaa
     5461 agactctgat ttcagcctgc cacctgggtc tgtttctggt cccgtgggga atccagtcgc
     5521 caagcttcag gatgtcttgg ctagtaatgc aggactgaca cagagtattc ccatccttcg
     5581 gcgggatcac cacatccaga gagccatcgg cctctccccc atgtctttcc ccactgcaga
     5641 cctcacgctg aagatggagt ctgcacgcaa ggcttgggaa aactccccca gtttgccgga
     5701 gcagaattct ccaggcggtg caggctcggg catccagcct ccatcctctg tgggcgcctc
     5761 caacggggtc aactacagct cctttggtgg cgtgtcaata ccgcccatgc ccgtggcttc
     5821 tgtagcgcct tctgcttcga tgccaggcag ccacctccca cctctgtact tggatggcca
     5881 cgtttttgca agtcagcccc gactggttcc tcagacgata cctcagcaac agagttacca
     5941 gcaggccgcc actgcccagc agatcccgat atcccttcac acgtctctgc aggcacaggc
     6001 gcagcttggg ctgaggggtg gacttcccgc ctcccagtcc caggagatct tcagctccct
     6061 gcagcctttc aggtctcagg tgtacatgca ccccagcctg tcaccaccca gcactatgat
     6121 cctctctggg ggcacggcct tgaaaccccc atactctgca tttcccggca tacagccctt
     6181 ggagatggtg aagccacaat ctggctcacc ctaccagccc atgagtggaa accaggccct
     6241 ggtctatgag ggccaactcg gccaggctgc tgggctgggt gcctcccaga tgctggactc
     6301 ccagctccca cagctaacta tgccactgcc tcggtatggc tccgggcagc agccactgat
     6361 cctgccacag tccattcagc tgcctccagg acagagtctc tccgttggag ccccccggag
     6421 gattcctcca cctggctccc aaccaccagt cctgaacacc agcagagagt ccactcagat
     6481 ggagttgaaa ggcttccact ttgccgacaa taaacagaat gtttctaccg gaggctccgc
     6541 accatccccg caggcctaca ggcctagctc tgctagcccc agtgggaagc cctctggatc
     6601 agcagttaac atgggctctg tgcagggaca ctacgttcaa caggccaagc gagtggatga
     6661 aaagcccagt ctgggaaccg tgaagctgca ggaggcctct tcagccacct cccagatgaa
     6721 gcgaactgga gcaatcaagc cacgggcagt caaggtggag gggagtaaag cctgaaggtg
     6781 cctggcatct cttgcctcac cctaacaggg atggtgcacc acaccagctt ggacagccac
     6841 cacctgggac ttgccagatc caccgtccca ctgtcctacc acctggcctg gacagagctc
     6901 tcttccactc ccgaaagctc ctgaaagttc catcgtcagc catcccacat cgtggatata
     6961 tggcattgac ctgcttgctt tggtacaaaa gagcagactc cctccttccc gcccctctgc
     7021 ccggtgactg tggagtgagc ctcagtgcag tgcagacctg cctgcccgcc ccgttcccta
     7081 ggcacagtgg tttggcagca gggtcatttt agctggaggc ttttttgttt taaaaagcag
     7141 ctaaggtttt tacaaagggg aaatgagaac aaaatgctag ctacgtctgt atagctgaac
     7201 ttttatacag tcctcgctgt cctctctgct ctgctgtccc cagtggtcgc cttttatctc
     7261 tgtcctgttt gacatgtcac agcgctacct taagaggtga ttcttaagag tcacagtctc
     7321 tctctctctc tctctctctc tctctctctc tcacacacac acacacacac acacacacac
     7381 acacacacac acacacacac aggttggcta atctttgggg tttggaggac atgaatggac
     7441 actctggttg gcccctaacc atcttgggca ctgtgaagtt ggtatctgag tttagctcca
     7501 gccgctggca tggagttaat gttccagaat aagaatgatc tgttctgggc ccttctgctg
     7561 tcgtggggca cactgagtac tgcacaccag aggaatgttg gagttagtca ccattttgta
     7621 atccagattg gccccactcg gggactgtga gctaaggctc cgtgctttag ccccttgggt
     7681 ggctttgttc cccactcact tcctttcctc tttgtgcagc ctgctgtgtc cgtctggatc
     7741 cctgtccatc catccacccc tcatggctta tcaccagaat caatataagg acacaggtag
     7801 acacccatta accaagtttg ccacaggaaa gactgtggcg ctcatcttgt gtccttcacc
     7861 cgtggcagca gggcaggctg ttgggggtag ggttgccaag caacaagtgt gttacccttc
     7921 cttagagaac tgggcggggt caaggtataa gagggcctgc agagaagcct atacagcctc
     7981 cctcagaggg tggcgtcttc cactgctgct gtttgtgtga gctcctgtgt gcgaagcttc
     8041 ttgcttccac taagaacgag gaagtttccc cgttgctcaa aggagaatga agggggattt
     8101 cagggtgctc agctgctgtc tgggatcccc atttaatcat ccgcctgggg atgctgaaga
     8161 ctgactgctt caaagagctc acagttggac aagggctggg acaaatgtgt gggtctgtcc
     8221 tcaagtgtca ccaggggcat gagagcagaa atgcagctta ggagctctga agtggcttcg
     8281 ccctgtctag ttggttgctg gaaggaagca caagtctccc cagcattacc agacagggca
     8341 gccttagtgc agagttccat tgcaactgca gcagtccgct ccttccttct cgcctctgct
     8401 ctccgacctt tgtccactct ctgtcccatc tcttctcttg catccctcct caaaagcact
     8461 ccacttagga gtcgctggca cagatctgcc tgtgccccta ctgctctccc ctgtaagtgt
     8521 ctggttactg tcccagtgat tgagtcctct gccccactgc caagctctac cctgtaagac
     8581 tcagtaaaag ccacacagtc acctctacct gtcctcctta gaaatgcggc cagacccacc
     8641 tcacctaatg cttggtgggc atgtgtcaaa agaagcaaac attttctcct tcagaatttt
     8701 cacaggatgc tgttacaaac tcaaagtgtg ccctttaggt gagcctgctg tcagaatggc
     8761 agtactccct gttaagaaaa attaggaggt cacctgtttt cagtcctttc tcaccctgta
     8821 tttccctcct gcctcccacc ctaaataaaa acaagaaaca ctagaattta tttatatgta
     8881 ttgatgttgt aggtctagat ggaaaaaaaa gtaaatgtcc cactgctctg tttatataat
     8941 gtctgaatta ctctgcaggg aaggccagga aattgcatgt gaaatttggt gtgctcatca
     9001 cctctgtggt ctcggctgtg ggcccctccc ctctgagagg cacatttgca actagactct
     9061 ggggacagag ggcaggcttc aggccaaagg tccctgccct cagatgatct ggttaagcca
     9121 aggttttagt acagaggttt taaggtgcaa tatctatctc ttcatgtggt tgttagagtc
     9181 aagctcaaag tgtaatagga cttgggcctt attttggttt caaaccccca tcttcagatc
     9241 acacataaaa acaggaacgt ctgtcaaggt gccatggcct ttggtgggaa cagataaagc
     9301 ccagtccctg ccttttctac tgctgagatg ggtggaggtg ggcagaatcc tttactcctg
     9361 tctgctgaag ccacctcctc ctgccagtgg cttcactggt gccactgacg gtgaaatcca
     9421 tggtttggca accaggactc ttcagtctgt tggtcctgat gcagcgtgta gcatctgttg
     9481 gtgatgactt ccgccagctg tatttagtct ggtctctcag cagttgcttt ccttgtctta
     9541 ttcccaagtt taccatcttc aagttcagag ttcacaggac acttctgggt ctgattcctt
     9601 acggggaata aatagcaggt ggctgctgtg cacgttcaga aaagctggtt cattttcaaa
     9661 gccagggctg ctctgctgct tctagattct tggataatgt gtcaacgtca accttgccgt
     9721 tctgtcttct ggagccacct tccagagggt ccatgatgaa gtcatgaagg atttgacacc
     9781 tagggcccag ggcacaaggg tgtgcccact gaggccatga ggcaactctg gctaagtctg
     9841 ccccgaaaca tcctgcatgt ttcctttcag tctaccttgc cctcattccc agcaagtctg
     9901 ggttagaggg tccgggggaa tcttacaagc aagggcacag gagtccatct tctgttttct
     9961 ttgatgagtg gggaagcgag ctcttttgtg agatggctct aagacaagtt aggtcatttg
    10021 gaacagactc atcggtgttg gttggggacg agcacagtca cccagctgtg ctctccacta
    10081 ggcctactag ctctgactag tgatcttcca ggcgcatgac acctgcagct cccagttgcc
    10141 tgcttcagac ctgcaacgtc cccaggcccc gtctttggca tgtcacagtc tcggagcagc
    10201 aggtcctgtg gaggctctgc aggctcctgt tggaaagggg tcctgtgccc tcagctgctt
    10261 tccaactcat accttttgta gaaaaggact tggggggggg ggggttgttc tttttgaggg
    10321 tccttttgtt tcttttgctt ttcttttggc cttccctctg tctttcactt agaccagcta
    10381 tctgaaaggg cagacgatgc taaaagtgtc ctgtgcagct tgtttagacg tgatatgggg
    10441 aacctcttac ttcggatggg aaatggaatc gtgaaatcac cctcccttcc ctccgggtca
    10501 gtccctgttg tttctccttt caaatatgtg attgtactag gtctttccat atgaaagaac
    10561 tctccttatt taaataaaaa aagtctaaaa aaaataaagc caaacatgct ttctca
//
