LOCUS       NM_001012121            1802 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus proline rich 5 (Prr5), mRNA.
ACCESSION   NM_001012121 XM_235544
VERSION     NM_001012121.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1802)
  AUTHORS   Gan,X., Wang,J., Wang,C., Sommer,E., Kozasa,T., Srinivasula,S.,
            Alessi,D., Offermanns,S., Simon,M.I. and Wu,D.
  TITLE     PRR5L degradation promotes mTORC2-mediated PKC-delta
            phosphorylation and cell migration downstream of Galpha12
  JOURNAL   Nat Cell Biol 14 (7), 686-696 (2012)
   PUBMED   22609986
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1802)
  AUTHORS   Laplante,M. and Sabatini,D.M.
  TITLE     mTOR signaling in growth control and disease
  JOURNAL   Cell 149 (2), 274-293 (2012)
   PUBMED   22500797
  REMARK    Review article
REFERENCE   3  (bases 1 to 1802)
  AUTHORS   Pearce,L.R., Sommer,E.M., Sakamoto,K., Wullschleger,S. and
            Alessi,D.R.
  TITLE     Protor-1 is required for efficient mTORC2-mediated activation of
            SGK1 in the kidney
  JOURNAL   Biochem J 436 (1), 169-179 (2011)
   PUBMED   21413931
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC090007.1.
            
            On Feb 11, 2005 this sequence version replaced XM_235544.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC090007.1, CK653260.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132263, SAMD00132268
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1802
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1802
                     /gene="Prr5"
                     /gene_synonym="Protor1"
                     /note="proline rich 5"
                     /db_xref="GeneID:315189"
                     /db_xref="RGD:1307954"
     exon            1..315
                     /gene="Prr5"
                     /gene_synonym="Protor1"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..1342
                     /gene="Prr5"
                     /gene_synonym="Protor1"
                     /note="protor-1; protein observed with Rictor-1; proline
                     rich 5 (renal)"
                     /codon_start=1
                     /product="proline-rich protein 5"
                     /protein_id="NP_001012121.1"
                     /db_xref="GeneID:315189"
                     /db_xref="RGD:1307954"
                     /translation="MRTLRRLKFMSSPSLSDLGKREPGAAGADERGTQQRRACANATW
                     NSIHNGVIAVFQRKGLPDQELFILNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRD
                     KIRFYEGQKLLDSLAETWDFFFSDVLPTLQAIFYPVQGKEPSVRQLALLHFRNTITLS
                     VKLEDALARSHACVPPAIAQMLLVLQGVHESRGVTEDYLRLETLIQKVVSPYLGTYGL
                     YSNEGPCTHSCILEKRFLRRSRSGDILAKNPVVRSKSYNTPLLNPVAEHEAEGTASGG
                     TSIRRHSVSEMTSCPEPQGFVDTPDQGPSGTFRSSPSPHSGPCPSRLYPPAHSPEQGP
                     DHGSPPTSSPETLVDQILESVDSDSEGIFIDFGRGSRSSVSDFEAAGGRPSVV"
     exon            316..396
                     /gene="Prr5"
                     /gene_synonym="Protor1"
                     /inference="alignment:Splign:2.1.0"
     exon            397..445
                     /gene="Prr5"
                     /gene_synonym="Protor1"
                     /inference="alignment:Splign:2.1.0"
     exon            446..503
                     /gene="Prr5"
                     /gene_synonym="Protor1"
                     /inference="alignment:Splign:2.1.0"
     exon            504..595
                     /gene="Prr5"
                     /gene_synonym="Protor1"
                     /inference="alignment:Splign:2.1.0"
     exon            596..736
                     /gene="Prr5"
                     /gene_synonym="Protor1"
                     /inference="alignment:Splign:2.1.0"
     exon            737..872
                     /gene="Prr5"
                     /gene_synonym="Protor1"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1737
                     /gene="Prr5"
                     /gene_synonym="Protor1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgctccgagc gctccacgct ccgccgccgc gagcaatggt tcacagggcc cggcgctggg
       61 cgtgcggccc ctggaggggg cgcagagccg ggacgggacg ccacggggtc gccgggcttg
      121 ctgctagcag ccgactatcg tcgtagggga cacggggcgc gcgtgggccg gggtgagcat
      181 gaggactctc cgcaggttga agttcatgag ttcgcccagc ctcagtgacc tgggcaagag
      241 ggagccgggc gcggcgggtg cggacgagcg gggcacgcag cagcgccggg cctgcgccaa
      301 cgccacctgg aacagtatcc acaacggtgt gattgccgtc tttcagcgca aggggctgcc
      361 cgaccaagag ctcttcatcc tcaacgaggg tgtccggcag ctgctgaaga cggagctggg
      421 gtccttcttc actgagtacc tgcagaacca gctgctgacc aagggcatgg tgattcttcg
      481 tgacaagata cgcttctacg agggacagaa gctgctggac tcactggcgg agacctggga
      541 cttcttcttc agtgatgtgc tgccgaccct gcaggccatc ttttaccctg tgcagggcaa
      601 ggagccgtcg gtgcgccagc ttgccctgtt gcatttccgg aacaccatca ccctcagcgt
      661 gaagctggag gacgcactgg cccgctccca cgcgtgtgtt ccccctgcca tcgcacagat
      721 gctgctggta ctgcagggag tacatgagtc caggggtgtg actgaagatt acctgcgcct
      781 cgagacattg atccagaagg tagtgtcacc atacctgggc acctatggac tctactccaa
      841 tgaagggccc tgtacccatt cctgtatcct tgagaaacgg ttcctacgcc gctcccgctc
      901 tggggatatc ctagccaaga acccagtggt gcgctccaaa agctacaata ctcccctgct
      961 caatcctgtg gctgagcatg aggcagaagg cacagcgtcc ggtggcacaa gcatccgcag
     1021 acactcagtc tccgagatga catcttgtcc tgagccccag ggctttgtgg acacgcctga
     1081 ccagggccct tcggggacct tcaggtcttc cccatcaccc cactcagggc cttgccccag
     1141 cagactatac ccccctgccc attcccccga acagggccca gaccatggct ccccacccac
     1201 ctccagccct gagacactcg tggaccagat cctggagtcc gtggactcag actccgaagg
     1261 gatattcatt gactttgggc ggggtagtcg ctccagtgtg tctgactttg aggcagcagg
     1321 cggccggccg agtgttgtgt gatggcctga ggttagttca tgtttttact gcccctgtgt
     1381 gtttgcgtgt ctgtgtatgt gtgtgtgaga gacttgttac tctttccaaa ccttgccggc
     1441 cccctgtctg tcactgcctc aagtcacttt gtactcccaa tctgttggaa aacccaccca
     1501 cccagatgca tactcaacca cctggaggaa tgggccacca tgtgccctcc cacctgcccc
     1561 actctcggtg cccacaactt acccaggaaa atgtgaacca gtgggctctg cctacgccag
     1621 cccagcctgg ccttcatagt gacgggactc aagccacaga cagacctgcc tgcctgcctc
     1681 cctctgccct ccgtggccac aaaacaggaa ggcatgaaat aaagttagag ctccaggaaa
     1741 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1801 aa
//
