LOCUS       NM_057131               1579 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus phosphoribosyl pyrophosphate
            synthetase-associated protein 2 (Prpsap2), mRNA.
ACCESSION   NM_057131
VERSION     NM_057131.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1579)
  AUTHORS   Bassett,J.H., Gogakos,A., White,J.K., Evans,H., Jacques,R.M., van
            der Spek,A.H., Ramirez-Solis,R., Ryder,E., Sunter,D., Boyde,A.,
            Campbell,M.J., Croucher,P.I. and Williams,G.R.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Rapid-throughput skeletal phenotyping of 100 knockout mice
            identifies 9 new genes that determine bone strength
  JOURNAL   PLoS Genet 8 (8), e1002858 (2012)
   PUBMED   22876197
REFERENCE   2  (bases 1 to 1579)
  AUTHORS   Sonoda,T., Ishizuka,T., Kita,K., Ishijima,S. and Tatibana,M.
  TITLE     Cloning and sequencing of rat cDNA for the 41-kDa
            phosphoribosylpyrophosphate synthetase-associated protein has a
            high homology to the catalytic subunits and the 39-kDa associated
            protein
  JOURNAL   Biochim Biophys Acta 1350 (1), 6-10 (1997)
   PUBMED   9003449
REFERENCE   3  (bases 1 to 1579)
  AUTHORS   Kita,K., Otsuki,T., Ishizuka,T. and Tatibana,M.
  TITLE     Rat liver phosphoribosyl pyrophosphate synthetase: existence of the
            purified enzyme as heterogeneous aggregates and identification of
            the catalytic subunit
  JOURNAL   J Biochem 105 (5), 736-741 (1989)
   PUBMED   2546925
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 26, 2020 this sequence version replaced NM_057131.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D84434.1, SRR22582419.683541.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-90                JAXUCZ010000010.1  46945214-46945303   c
            91-208              JAXUCZ010000010.1  46939843-46939960   c
            209-359             JAXUCZ010000010.1  46939459-46939609   c
            360-412             JAXUCZ010000010.1  46938330-46938382   c
            413-479             JAXUCZ010000010.1  46936101-46936167   c
            480-652             JAXUCZ010000010.1  46932355-46932527   c
            653-768             JAXUCZ010000010.1  46928503-46928618   c
            769-824             JAXUCZ010000010.1  46924044-46924099   c
            825-973             JAXUCZ010000010.1  46916976-46917124   c
            974-1044            JAXUCZ010000010.1  46915249-46915319   c
            1045-1191           JAXUCZ010000010.1  46912047-46912193   c
            1192-1579           JAXUCZ010000010.1  46910542-46910929   c
FEATURES             Location/Qualifiers
     source          1..1579
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..1579
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /note="phosphoribosyl pyrophosphate synthetase-associated
                     protein 2"
                     /db_xref="GeneID:117272"
                     /db_xref="RGD:620207"
     exon            1..90
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     exon            91..208
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     exon            209..359
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..1350
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /note="PRPP synthetase-associated protein 2; 41 kDa
                     phosphoribosypyrophosphate synthetase-associated protein;
                     PRPP synthase-associated protein 2"
                     /codon_start=1
                     /product="phosphoribosyl pyrophosphate synthase-associated
                     protein 2"
                     /protein_id="NP_476472.1"
                     /db_xref="GeneID:117272"
                     /db_xref="RGD:620207"
                     /translation="MFCVAPPELETKMNITKGGLVLFSANSNSSCMELSKKIAERLGV
                     EMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAK
                     SIIGVIPYFPYSKQCKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPV
                     DNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAE
                     SDLVDGRHSPPMVRSVAAIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVD
                     SFLAAAETLKERGAYKIFVMATHGLLSSDAPRLIEESAIDEVVVTNTIPHEIQKLQCP
                     KIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD"
     exon            360..412
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     exon            413..479
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     exon            480..652
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     exon            653..768
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     exon            769..824
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     exon            825..973
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1044
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1191
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..1579
                     /gene="Prpsap2"
                     /gene_synonym="Pap41"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccattttgc tgtaagacgc tgtgcggagc tctgagctct tttccttcgg cagccgaggc
       61 tgcggcgggc cgggctgggg tcgggaccag gaagaataac agagaggtta acagaataca
      121 ggataacagg agaataacag gaggttgtcc ataattgact ttaagcagca aacagtaaaa
      181 cactgagctc ttcagctccg cctttcttgc tcttagaatt ggaacgccaa gaaggttttg
      241 atgttttgtg tggcgcctcc tgaattagaa accaagatga acataaccaa aggaggcctc
      301 gtgttgtttt cagcaaattc caattcatca tgtatggagc tttcaaagaa aattgcagag
      361 cggctggggg tggagatggg caaagtgcag gtttaccagg aacctaacag agaaacacga
      421 gttcaaatcc aggagtctgt gagagggaaa gatgtattta tcattcagac cgtctcgaag
      481 gacgtgaaca ccaccatcat ggagctcctg attatggtat atgcatgtaa gacctcttgt
      541 gccaagagca tcattggagt gatcccctac tttccttata gcaagcagtg caagatgaga
      601 aaaaggggct ctattgtctc aaaattgctg gcttctatga tgtgcaaagc tggtctgact
      661 catcttatca ctatggattt acaccagaag gaaatccagg gcttcttcaa tattccagtg
      721 gataatttaa gagcctcccc tttcctgtta cagtatattc aagaagagat cccagattat
      781 aggaatgcag tcatcgtggc caagtctcca gcctcagcca agagggcaca atcttttgca
      841 gagcgtctac gcctggggat cgcagtgatc catggagaag cacaggatgc tgagtctgac
      901 ttggtggatg gccggcactc cccaccaatg gtcaggagtg tagctgccat ccaccccagc
      961 ctggagatcc caatgctgat tcctaaagaa aagcccccaa tcacagttgt tggtgatgtt
     1021 ggaggaagaa ttgccatcat cgtggatgac attattgatg atgtggacag ctttcttgct
     1081 gcagcagaga ccctaaagga aagaggtgca tataagatct ttgtgatggc aactcacggc
     1141 ttgttatcct ctgatgctcc ccggctgatt gaagagtctg ccattgatga ggtggtggtc
     1201 actaacacga tcccacatga aatccagaag ttgcagtgcc ccaagatcaa gactgtggac
     1261 atcagcatga tcctctcaga agccatccgc cgaattcaca acggggagtc catgtcctac
     1321 cttttcagaa acataggctt agatgactga acagttctcc tatggcagaa ctcccacagg
     1381 tcaagtggga ggcccagcat atatgctgga aggcccatgc ccagctagat acttgaccct
     1441 cccttcctga catcttcctg attgattcct gtgaaggtac aaggaccagc tttcttaatg
     1501 ttggtttagg tttttgtgag tttgggggat aatttttata acagaaagac ctcctcttaa
     1561 ataaaagaag ttaaaacct
//
