LOCUS       NM_022545               1723 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Rattus norvegicus phosphoribosyl pyrophosphate
            synthetase-associated protein 1 (Prpsap1), mRNA.
ACCESSION   NM_022545
VERSION     NM_022545.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1723)
  AUTHORS   Xin,X., Rual,J.F., Hirozane-Kishikawa,T., Hill,D.E., Vidal,M.,
            Boone,C. and Thierry-Mieg,N.
  TITLE     Shifted Transversal Design smart-pooling for high coverage
            interactome mapping
  JOURNAL   Genome Res 19 (7), 1262-1269 (2009)
   PUBMED   19447967
REFERENCE   2  (bases 1 to 1723)
  AUTHORS   Ishijima,S., Asai,T., Kita,K., Sonoda,T. and Tatibana,M.
  TITLE     Partial reconstitution of mammalian phosphoribosylpyrophosphate
            synthetase in Escherichia coli cells. Coexpression of catalytic
            subunits with the 39-kDa associated protein leads to formation of
            soluble multimeric complexes of various compositions
  JOURNAL   Biochim Biophys Acta 1342 (1), 28-36 (1997)
   PUBMED   9366267
REFERENCE   3  (bases 1 to 1723)
  AUTHORS   Ishizuka,T., Sawa,K., Kita,K., Ino,H., Sonoda,T., Suzuki,N. and
            Tatibana,M.
  TITLE     Promoter region of the rat phosphoribosylpyrophosphate
            synthetase-associated protein 39
  JOURNAL   Biochim Biophys Acta 1306 (1), 34-37 (1996)
   PUBMED   8611622
REFERENCE   4  (bases 1 to 1723)
  AUTHORS   Kita,K., Ishizuka,T., Ishijima,S., Sonoda,T. and Tatibana,M.
  TITLE     A novel 39-kDa phosphoribosylpyrophosphate synthetase-associated
            protein of rat liver. Cloning, high sequence similarity to the
            catalytic subunits, and a negative regulatory role
  JOURNAL   J Biol Chem 269 (11), 8334-8340 (1994)
   PUBMED   8132556
REFERENCE   5  (bases 1 to 1723)
  AUTHORS   Kita,K., Otsuki,T., Ishizuka,T. and Tatibana,M.
  TITLE     Rat liver phosphoribosyl pyrophosphate synthetase: existence of the
            purified enzyme as heterogeneous aggregates and identification of
            the catalytic subunit
  JOURNAL   J Biochem 105 (5), 736-741 (1989)
   PUBMED   2546925
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB736123.1 and BC078822.1.
            
            On Apr 25, 2008 this sequence version replaced NM_022545.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078822.1, D26073.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                CB736123.1         51-75
            26-1723             BC078822.1         1-1698
FEATURES             Location/Qualifiers
     source          1..1723
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..1723
                     /gene="Prpsap1"
                     /note="phosphoribosyl pyrophosphate synthetase-associated
                     protein 1"
                     /db_xref="GeneID:64390"
                     /db_xref="RGD:620206"
     exon            1..332
                     /gene="Prpsap1"
                     /inference="alignment:Splign:2.1.0"
     CDS             163..1320
                     /gene="Prpsap1"
                     /EC_number="2.7.6.1"
                     /note="PAP39; PRPP synthetase-associated protein 1; 39 kDa
                     phosphoribosypyrophosphate synthetase-associated protein;
                     PRPP synthase-associated protein 1; 39 kDa
                     phosphoribosypyrophosphate synthase-associated protein;
                     phosphoribosylpyrophosphate synthetase-associated protein
                     (39 kDa)"
                     /codon_start=1
                     /product="phosphoribosyl pyrophosphate synthase-associated
                     protein 1"
                     /protein_id="NP_071990.2"
                     /db_xref="GeneID:64390"
                     /db_xref="RGD:620206"
                     /translation="MPRKLLLLPQLSACSALRVPRARPAASPAMNAARTGYRVFSANS
                     TAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTA
                     VMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHII
                     TMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAE
                     RLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDV
                     GGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEV
                     VVTNTVPHELQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD"
     exon            333..385
                     /gene="Prpsap1"
                     /inference="alignment:Splign:2.1.0"
     exon            386..452
                     /gene="Prpsap1"
                     /inference="alignment:Splign:2.1.0"
     exon            453..625
                     /gene="Prpsap1"
                     /inference="alignment:Splign:2.1.0"
     exon            626..741
                     /gene="Prpsap1"
                     /inference="alignment:Splign:2.1.0"
     exon            742..797
                     /gene="Prpsap1"
                     /inference="alignment:Splign:2.1.0"
     exon            798..943
                     /gene="Prpsap1"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1014
                     /gene="Prpsap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1161
                     /gene="Prpsap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1696
                     /gene="Prpsap1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgctcggtt gcggcgctgt tgcctgtggt cgggacgcgg aggcggcgcg tcggtatcgc
       61 gcctcgtccc tctgcgcctc cgccggtggc tgcgtcggcg tcacagctgt gcccacatcc
      121 cgccccgcgc ggaccgcttg tagccgcttc tcgggccgga ggatgcccag gaagctgctg
      181 ctactgcccc agctgtccgc gtgctccgct ctgcgcgtcc cgcgggcccg gcccgccgcc
      241 tcgccggcca tgaacgccgc ccgcactggc taccgagtct tttcggccaa ctccacggcc
      301 gcctgcacgg agctggccaa gcgcatcact gagcgtcttg gtgctgaatt ggggaaatct
      361 gttgtttatc aggagaccaa tggagaaacc agagttgaaa tcaaagagtc tgttcgtggc
      421 caagatattt tcattataca aaccataccc agagatgtga atacggccgt gatggagctg
      481 ctgatcatgg cgtacgccct gaagactgcc tgtgccagga atatcatcgg tgtcatcccc
      541 tacttcccct acagcaaaca aagcaagatg aggaagaggg gctccattgt gtgcaagctc
      601 ctggcatcca tgctggcaaa agctggtcta actcacatta tcactatgga tcttcaccaa
      661 aaggaaatac aaggcttttt ctgcttcccc gtggacaacc ttagagcctc acctttcctg
      721 ctccagtata tccaggaaga aattccaaat tacagaaatg cagtcattgt agctaagtct
      781 cctgatgctg caaaaagggc tcagtcctat gcagagagac tacgcctggg cctggctgtg
      841 atccacggag aagctcagtg cacagagcta gacatggatg acggtcgaca ctcacccccc
      901 atggtcaaga acgccactgt gcaccccggc ctggagctac ccttgatgat ggccaaagag
      961 aagccaccaa taacagtggt cggagacgtc gggggacgca ttgcaatcat agtggatgac
     1021 atcattgatg atgtggagag ctttgttgct gctgcagaga ccctgaaaga gagaggtgct
     1081 tacaagatct atgtcatggc cacgcacggc atcctgtctg ctgaagctcc ccgtctgatc
     1141 gaggagtccc ccattgatga ggtggtggtg acgaacactg tccctcacga gcttcagaaa
     1201 ctacagtgtc ccaagataaa gactgtggac atcagcttga ttctttctga ggcgattcgg
     1261 agaatccata atggcgaatc catggcttac ctcttccgga acatcacagt ggatgattag
     1321 ctccgagctg ccttgacctg caggggagca cacagcagtg tcagccggca gacaggctgc
     1381 cgagtccctt ctcccccatc agcagaatgc agcctatttg ggaatacgtc ctgcggaaga
     1441 ggcaggctct gtcacagcag gcatccagtt gtagactgag tccccacgct ggtttgttca
     1501 ctagtgtctg ctctggggaa ggcaggtgag gcgttgagct tggtcaggga gctgagtggc
     1561 cctggcactg atgcgtgcag ttgtaccatt ggacatgaag ggtccccggc tgctttcacg
     1621 gagctcgtca gatgagagcg gagcagcctg tccctcagaa ctgtgttgct gcaaataaaa
     1681 gtttcttatc tccctaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
