LOCUS       NM_001011923            4378 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus pre-mRNA processing factor 4B (Prpf4b), mRNA.
ACCESSION   NM_001011923 XM_214469
VERSION     NM_001011923.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4378)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 4378)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   3  (bases 1 to 4378)
  AUTHORS   Jurica,M.S., Licklider,L.J., Gygi,S.R., Grigorieff,N. and
            Moore,M.J.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   4  (bases 1 to 4378)
  AUTHORS   Tate,P., Lee,M., Tweedie,S., Skarnes,W.C. and Bickmore,W.A.
  TITLE     Capturing novel mouse genes encoding chromosomal and other nuclear
            proteins
  JOURNAL   J Cell Sci 111 (Pt 17), 2575-2585 (1998)
   PUBMED   9701556
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085927.1.
            
            On Feb 11, 2005 this sequence version replaced XM_214469.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085927.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..4378
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p12"
     gene            1..4378
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /note="pre-mRNA processing factor 4B"
                     /db_xref="GeneID:291078"
                     /db_xref="RGD:1307784"
     exon            1..85
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..3068
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /EC_number="2.7.11.1"
                     /note="PRP4 pre-mRNA-processing factor 4 homolog; PRP4
                     pre-mRNA processing factor 4 homolog B"
                     /codon_start=1
                     /product="serine/threonine-protein kinase PRP4 homolog"
                     /protein_id="NP_001011923.1"
                     /db_xref="GeneID:291078"
                     /db_xref="RGD:1307784"
                     /translation="MAATEPPSLREQPEMDDADNSEKSVNEENGEVSEDQSQNKHSRH
                     KKKKHKHRSKHKKHKHSSEEDRDKKHKHKHKHKKHKRKEVLDASDKEGLSPAKRTKLD
                     DLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNR
                     SSTRSSSTRGKLEITDNKNSAKKRSKSRSKERTRHRSDKRKSKGAVEMMREKANRSKS
                     KERRKSKSPSKRSKSQDQARKSKSPTLRRRSQEKVGKARSPADEKIKSEEKGKIKDRK
                     KSPIVNERSRDRSKKSKSPVDLRDKSKDRRSRSKERKSKRSEIDKEKKPIKSPSKDAS
                     SGKENRSPSRRPGRSPKRRSLSPKQRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRA
                     KSRSLERKRREPERRRLSSPRTRPRDDILGRCERSKDASPINRWSPSRRRSRSPIRRR
                     SRSPLRRSRSPRRRSRSPRRRDRSRRSRSRLRRRSRSRGGHRRRSRSKVKEDKFKGSL
                     SEGMKVEQESSSDDNLEDFDVEEEDEEAVIEQRRIQRQAIVQKYKYLAEDSNISVPSE
                     PSSPQSSTRSRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVEQNNGSSQ
                     KKLLAPDMFTESDDMFAAYFDSARLRAAGIGKDFKENPNLRDNWTDAEGYYRVNIGEV
                     LDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKELEFLKKLN
                     DADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVRSYSQQ
                     LFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLVSRFYR
                     APEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMIR
                     KGVFKDQHFDQNLNFMYIEVDKVTEREKVTVMSTINPTKDLLADLIGCQRLPEDQRKK
                     VHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI"
     exon            86..1282
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1456
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            1457..1612
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            1613..1694
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            1695..1905
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            1906..1979
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            1980..2070
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            2071..2218
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2356
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            2357..2510
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2625
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            2626..2777
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            2778..2864
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
     exon            2865..4353
                     /gene="Prpf4b"
                     /gene_synonym="Prp4k"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcggagccg ccgccagcac cgcggagaag tcgggaagtt caagatggcc gccacggagc
       61 ccccgtcgct gcgggagcaa cctgagatgg acgatgctga taattctgaa aagagtgtaa
      121 atgaggaaaa tggagaagta tcagaagacc agtctcaaaa taaacacagt cgtcataaaa
      181 aaaagaagca taaacacaga agtaaacata agaaacataa acattcctca gaagaagata
      241 gggataaaaa acacaaacac aagcataagc ataagaaaca caaaagaaaa gaagttctcg
      301 atgcctctga caaggaaggc ctgtcccctg ccaaaagaac taaacttgat gatttagctt
      361 tgctggaaga cttggaaaaa cagagagcct tgatcaaagc tgagctcgat aacgagttaa
      421 tggaggggaa ggtccagtct ggaatggggc tcattctgca gggctatgag tctggctctg
      481 aagaagaagg agagattcac gaaaaggcaa gaaatggaaa taggtccagt accaggtctt
      541 ccagtacacg gggaaaactt gaaattacag acaacaaaaa tagtgcaaaa aaacgaagta
      601 agagcagatc caaagaacga actaggcata ggtcagacaa aaggaagagc aagggagctg
      661 tcgaaatgat gagagaaaaa gcaaacagga gcaagtctaa ggagaggaga aaatccaaaa
      721 gtccatccaa aagaagcaaa tctcaagacc aagcaagaaa atcaaagtcc cctaccctta
      781 gacggcggtc ccaagagaag gtggggaagg ctagatctcc tgctgacgag aagattaaga
      841 gtgaagagaa aggtaaaata aaggatagga aaaaatcacc aattgtaaat gaaagaagtc
      901 gagatagatc taaaaaatcc aagtccccag ttgacttaag agataaatcc aaagacagaa
      961 ggtcgaggtc caaagagcgg aagtcaaaac gatctgagat tgacaaagaa aagaagccaa
     1021 ttaaatcacc ttcaaaagat gcttcttctg ggaaggaaaa taggtcaccc agtagaagac
     1081 ctggccgtag tcctaaaaga agaagtttgt ctccaaaaca acgagacaag tcaagaagaa
     1141 gtaggtctcc gcttctcaat gacaggagat ctaagcagag caaatcacct tctcgaactc
     1201 tctctccagg cagaagggcc aagagccgat ccttagaaag gaaacggaga gaaccagaga
     1261 ggagacggct ttcttctccg agaacacgac ctcgagatga tatccttggt agatgtgaac
     1321 gatcaaagga tgccagcccc attaacaggt ggtctccaag ccgaagaaga agtaggtctc
     1381 ccattagaag gagatcccgt tccccattga gacgcagcag gtctcctaga agaagaagca
     1441 ggtctcctcg aagaagagat aggagtcgaa ggagcaggtc acgcttgaga agaagatctc
     1501 gatcacgggg tggtcatagg agaaggagca gaagcaaagt aaaggaagat aaatttaaag
     1561 gaagcctctc ggaaggaatg aaagttgagc aagagtcttc gtctgatgat aaccttgaag
     1621 attttgatgt ggaggaagaa gatgaagagg ctgtaataga acagagaagg atacagaggc
     1681 aagcaattgt gcagaaatat aagtatcttg cggaagatag caatatatct gtgccatctg
     1741 agccaagcag cccccagagc agcacaagat cacggtcccc ttcgccagac gacatcttgg
     1801 agcgggtagc tgctgacgta aaagaatatg agcgggagaa tgttgacaca tttgaagcct
     1861 cagtaaaagc caagcataat ctaatgacag ttgaacagaa taatggctca tctcagaaga
     1921 agcttttggc acctgatatg tttacagaat ccgatgatat gtttgctgct tattttgata
     1981 gtgctcgtct ccgggccgct ggcattggga aagatttcaa agagaatccc aacctcagag
     2041 ataattggac agatgcagaa ggctattacc gtgtgaacat cggggaagtc ctagataagc
     2101 gctataatgt atatggctac actgggcagg gtgtgttcag taatgtagtc cgtgccaggg
     2161 ataatgcaag agccaatcag gaagtggctg taaagatcat caggaacaat gaactcatgc
     2221 aaaagactgg tttaaaggaa ctagagttct tgaagaaact gaacgatgct gatcctgatg
     2281 acaagttcca ttgcctacgc ctcttcagac acttttacca caaacagcat ctctgtcttg
     2341 tatttgagcc tctcagtatg aatttgcgag aggtattaaa aaaatatggt aaggatgtcg
     2401 gtcttcatat taaggctgta cgatcgtaca gtcagcagtt gttcctggca ttgaaactcc
     2461 ttaaaagatg taatatccta catgcagata tcaaaccaga taatattctg gttaatgaat
     2521 ccaaaacaat tttaaagctt tgtgattttg gatcggcgtc acatgttgca gacaatgaca
     2581 taacgcctta tcttgtcagt agattttatc gtgctccgga gatcattata ggtaaaagct
     2641 atgactatgg tatcgatatg tggtctgtag gttgtacctt atatgaactc tatactggaa
     2701 aaatcttatt tcctggcaaa actaataacc acatgttgaa gctcgccatg gaccttaaag
     2761 gaaaaatgcc aaataagatg atccggaaag gtgtattcaa agatcaacat tttgaccaaa
     2821 atctgaactt catgtacata gaagttgata aagtaacaga gagggagaaa gttactgtca
     2881 tgagcaccat taatccaact aaggacctat tggctgactt gattgggtgc cagcgacttc
     2941 ctgaagatca acgtaaaaaa gtacaccagc taaaggactt gttggaccag atcctaatgt
     3001 tggacccagc taagcgaatt agcatcaacc aggccctgca gcatgcattc atccaggaaa
     3061 aaatttaaat gagatgaaga aactccaagg gtttgagtaa ttaaatacaa agactgaaga
     3121 aatttcacag cagtttatta ttaatgtata taaacttata aatatttctg cagcaaattt
     3181 gaggaagcat gatatatttg aattaacacc gagggtgata tttcttttag aaatgttagt
     3241 taatctgttt tgtgtcttat gtgaaatttc actgtagaaa tgttttaatt gccaagactg
     3301 cacagaatta cagtgctaat gtacatggtt gcagttcaca taaagacaaa aagcatctgt
     3361 tatgagtagc agtgctgggt ggttgatttg ttcttagcag acttggcttc agtttgctct
     3421 tcagatacaa tggccagcat aaatgctgtt tatattcacg tttccctagg tgtgtgtgtg
     3481 caggccacag cagcatgccc ttggtgtagt cagtgccgaa gggagtctgt tccttcttga
     3541 gcctgcctgc agggatgtct cctcttttaa agcaggttgt gtacaacatt cagtacactg
     3601 aaggtaagct aaaccatcaa catcaccagt gttttaagat gttattttat tggaataatt
     3661 gaaaatgagg gatagctttg tggcggaatt ccctgcatgt gtgataactg atcttgtttt
     3721 cttttttcgc atcgcgactg tggcatagtt acagtttctg ttctgttcat cacatttaaa
     3781 attcgaagcg tatgcgcttg atgggtagag cgccttcagt gtactgtttc ctattaactt
     3841 tacttttttt taaatcaact tgctatagac tttatacatt ttgttaaata cagttcttag
     3901 tgacatagaa actgcatagt tttcatttac taattaaaat gttgaggcct acttcccaaa
     3961 gtcctcatat ttaaaagata gacaacataa tgagattttt aactatttgt atgtcatttt
     4021 ggaagtgtac tgctttatgg taaacgtgtt tttcatttgt tcattgtttg cattatttgt
     4081 gatcatgttg tctttcaata caggcataaa ccttccactc ttgaacaaag cagctgcttt
     4141 ttaaaagcgg taattgcttc tttacctttt atttcttttg taaatgaagc ttttctttta
     4201 aaatgtgact ttaaagtgtt gtctattgca taaacagttg acactcactt actgtaatga
     4261 gaagattgtt ctactgcatg ggaagtggac catgcagatt tctgtatgtt ctcagtatgc
     4321 atcactagat aataaagtct tttgtgaaca aggaaaaaaa aaaaaaaaaa aaaaaaaa
//
