LOCUS       NM_001106480            3564 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus pre-mRNA processing factor 40 homolog A
            (Prpf40a), mRNA.
ACCESSION   NM_001106480 XM_001056963 XM_215739
VERSION     NM_001106480.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3564)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 3564)
  AUTHORS   Bai,S.W., Herrera-Abreu,M.T., Rohn,J.L., Racine,V., Tajadura,V.,
            Suryavanshi,N., Bechtel,S., Wiemann,S., Baum,B. and Ridley,A.J.
  TITLE     Identification and characterization of a set of conserved and new
            regulators of cytoskeletal organization, cell morphology and
            migration
  JOURNAL   BMC Biol 9, 54 (2011)
   PUBMED   21834987
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3564)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 3564)
  AUTHORS   Ramirez-Espain,X., Ruiz,L., Martin-Malpartida,P., Oschkinat,H. and
            Macias,M.J.
  TITLE     Structural characterization of a new binding motif and a novel
            binding mode in group 2 WW domains
  JOURNAL   J Mol Biol 373 (5), 1255-1268 (2007)
   PUBMED   17915251
REFERENCE   5  (bases 1 to 3564)
  AUTHORS   Sayer,J.A., Manczak,M., Akileswaran,L., Reddy,P.H. and Coghlan,V.M.
  TITLE     Interaction of the nuclear matrix protein NAKAP with HypA and
            huntingtin: implications for nuclear toxicity in Huntington's
            disease pathogenesis
  JOURNAL   Neuromolecular Med 7 (4), 297-310 (2005)
   PUBMED   16391387
REFERENCE   6  (bases 1 to 3564)
  AUTHORS   Hilditch-Maguire,P., Trettel,F., Passani,L.A., Auerbach,A.,
            Persichetti,F. and MacDonald,M.E.
  TITLE     Huntingtin: an iron-regulated protein essential for normal nuclear
            and perinuclear organelles
  JOURNAL   Hum Mol Genet 9 (19), 2789-2797 (2000)
   PUBMED   11092755
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473983.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_215739.4, XM_001056963.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3564
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q12"
     gene            1..3564
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /note="pre-mRNA processing factor 40 homolog A"
                     /db_xref="GeneID:295607"
                     /db_xref="RGD:1311401"
     CDS             1..2862
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /note="formin binding protein 3; PRP40 pre-mRNA processing
                     factor 40 homolog A"
                     /codon_start=1
                     /product="pre-mRNA-processing factor 40 homolog A"
                     /protein_id="NP_001099950.1"
                     /db_xref="GeneID:295607"
                     /db_xref="RGD:1311401"
                     /translation="MRPGTGAERGGLMVSEMESQPPSRGPGDGERRLSGSNLCSSSWV
                     SADGFLRRRPSMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQMPG
                     MMSSVMSGMMMSHMSQASMQPALPPGVNSMDVAAGAASGAKSMWTEHKSPDGRTYYYN
                     TETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDL
                     EGYQNTIVAGGLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEA
                     AAAVVAAAAAAAAAANANTSTTPTNTVGSVPVAPEPEVTSIVATAVDNENTVTASAEE
                     QAQLANTTALQDLSGDISSNTGEEPPKQETVTDFTPKKEEEESQPAKKTYTWNTKEEA
                     KQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKE
                     EARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVL
                     FFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQ
                     NMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQIFLDELHEHGQLH
                     SMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDK
                     GFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMK
                     RKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEH
                     ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESHSASEHSSSA
                     ESERSYKKSKKHKKKSKKRRHKSDSPESDTEREKDKKEKDRESEKDRSRQRSESKHKS
                     PKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ"
     exon            1..165
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            166..297
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            298..378
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            379..409
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            410..426
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            427..537
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            538..658
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            659..712
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            713..737
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            738..1100
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1209
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1274
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1439
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1548
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1699
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1700..1833
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1834..1948
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1949..2040
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..2157
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2158..2295
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2296..2391
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2392..2478
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2479..2575
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2576..2637
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2638..2769
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2770..3564
                     /gene="Prpf40a"
                     /gene_synonym="Fnbp3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaggccgg ggactggagc cgagcgtgga ggcctcatgg tgagtgaaat ggagagccaa
       61 cctccctcgc ggggtcccgg ggacggggag cggagattgt ccggctcaaa cctgtgctcc
      121 agttcttggg tctctgctga cggcttcctg aggagacggc cctcgatggg gcatcctggc
      181 atgcattatg caccaatggg catgcaccct atgggtcagc gagcaaacat gcctcctgta
      241 cctcacggaa tgatgccaca gatgatgcct cctatgggag ggcctccaat gggacaaatg
      301 cctggaatga tgtcttcagt aatgtcagga atgatgatgt ctcatatgtc tcaggcttcc
      361 atgcaacctg ctttaccgcc tggagtgaac agtatggatg tagcagcagg tgcagcatct
      421 ggtgcgaaat caatgtggac agaacataaa tcacctgatg gaaggactta ttactataat
      481 actgaaacaa aacagtctac ctgggaaaag ccagatgatc ttaaaacacc tgctgagcaa
      541 ctattgtcta aatgcccatg gaaagagtac aaatctgatt ctgggaagcc ttattactat
      601 aattctcaaa caaaagagtc ccgctgggcc aaacctaagg aacttgaaga tcttgaagga
      661 taccagaata ccattgttgc tggaggtctt attacaaaat caaacctgca tgccatgatc
      721 aaagcagaag aaagcagcaa gcaagaagaa tgtactacaa catcaacagc cccagttcct
      781 acgacagaaa ttcctaccac tatgagcacc atggctgctg cagaagcagc agctgctgtt
      841 gtcgcagctg ctgcagccgc tgcagcagca gctaatgcca atacttccac cacacctact
      901 aatactgtgg gaagtgttcc agttgctcct gaacctgaag ttacttccat tgttgctact
      961 gctgttgata atgagaatac agtgactgca tcagctgagg agcaagcaca gcttgctaat
     1021 actacagctc ttcaagacct aagtggcgat atatccagta acactggaga ggaaccacct
     1081 aaacaagaaa ctgtaaccga ttttactcct aaaaaagaag aggaagagag ccaaccagca
     1141 aaaaaaacat atacttggaa tacaaaggag gaggcaaagc aagcatttaa agaattattg
     1201 aaagaaaagc gggtaccctc caatgcttca tgggagcaag ctatgaaaat gatcataaat
     1261 gatcctcggt acagtgcttt agcaaagctg agtgagaaga agcaggcatt taatgcctat
     1321 aaagtccaga cagagaagga ggaaaaagaa gaagcaagat caaaatacaa agaagctaag
     1381 gaatcctttc agcgttttct tgaaaatcat gaaaaaatga cttccacaac cagatacaaa
     1441 aaagctgagc aaatgtttgg ggagatggaa gtttggaatg caatatcaga gcgtgatcgt
     1501 cttgaaatct atgaagacgt tttgttcttc ctttcaaaga aagaaaagga acaagcaaag
     1561 cagttacgaa agagaaattg ggaagcctta aaaaacatac ttgacaatat ggctaatgtt
     1621 acatactcta ccacttggtc tgaagcccag cagtatctga tggataatcc aacgttcgca
     1681 gaggatgaag agttacagaa catggataaa gaagatgcat taatatgctt tgaggaacac
     1741 atccgagctt tagaaaagga agaagaagaa gaaaaacaga agactttgtt gagagaaagg
     1801 aggaggcagc gtaaaaatag ggaatctttt cagatctttc tagacgagtt gcatgagcac
     1861 gggcagctgc actctatgtc ctcttggatg gagctgtatc cgaccattag ctctgacatt
     1921 cgattcacta atatgctggg tcagcctgga tcaactgcac ttgatctttt caagttttat
     1981 gttgaagatc ttaaagcacg atatcatgat gaaaaaaaga taataaaaga cattctgaag
     2041 gataaaggat ttgtagttga agtaaacact acttttgaag attttgtggc aataatcagt
     2101 tcaaccaaaa gatcaaccac tttggatgct ggaaatatca agttggcttt caatagttta
     2161 ctagaaaagg cagaagcccg tgaacgtgag agagaaaagg aagaagctcg gaaaatgaaa
     2221 cgaaaagagt ctgcctttaa gagtatgttg aaacaggcca ctcctccaat agaactggat
     2281 gctgtctggg aagatatccg ggaaagattt gtgaaggaac cagcatttga ggatataact
     2341 ctagaatctg aaagaaaaag aatatttaaa gatttcatgc atgtgcttga gcatgaatgt
     2401 cagcatcatc attcaaagaa caagaaacat tctaagaaat ctaaaaaaca ccataggaaa
     2461 cgctcccgct ctcgatcggg atcagactca gatgatgatg acagccattc aaagaaaaaa
     2521 agacagcgat cagaatccca ttctgcttca gaacattctt ctagtgctga gtctgagaga
     2581 agttacaaga aatcaaaaaa gcataagaag aaaagcaaaa agaggagaca taaatctgac
     2641 tctccagaat cagatactga acgagagaag gataaaaaag aaaaagatcg ggaaagtgaa
     2701 aaagacagaa gtaggcagag atcagaatca aaacacaaat cacctaagaa aaagactgga
     2761 aaggattctg gtaactggga tacttctggc agtgaactga gtgaagggga attagaaaag
     2821 cgcagaagaa cccttttgga gcaactggac gatgatcaat aaattatacc aaatatatgt
     2881 ttatagtatg atttaaagtc taattcagac cagggattat tttaagtcca atttacataa
     2941 cactgggttt taattgtgtc acaggaaaaa agtgcattta tgtattgtta ttgtggactt
     3001 tataaaagca aaggaaattg aaaataactt gattctgtct caagaatcat attttcctat
     3061 ggtgataact gtctctctgt gaccctttca tagggcacta caggatggat taaaagtggc
     3121 aattgaatga tagctgcaga cgtctctgct ttgttttaag tcaggaggtg acctgatttc
     3181 ctttatacaa gttggatttt gaagatacaa tgacaatttt ttgataatgt agtacaaaaa
     3241 aagcaccagc aacctatgag aagactgctt ttttgtgcac tactgaactg gttaaagcca
     3301 acgtgaactt ttctggtgag ctcttaagaa ataggtgttt ttgatggaaa ctgggtagac
     3361 ctctaatgta gtggtgccaa tgagcgctgc tgtaataaag acaccattat tttttatgga
     3421 acatctgaac attttaaaaa ggctcatgag ggcattattt tgggcatcta ttttgaggtg
     3481 atgttttaaa atagctaaca tcaagtcaaa ttgtaaatta gtttaaatat attgccttaa
     3541 ggacctacta aagaatgtgc cacc
//
