LOCUS       NM_001106672            1656 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus pre-mRNA processing factor 38A (Prpf38a), mRNA.
ACCESSION   NM_001106672 XM_001060413 XM_216475
VERSION     NM_001106672.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Bertram K, Agafonov DE, Dybkov O, Haselbach D, Leelaram MN, Will
            CL, Urlaub H, Kastner B, Luhrmann R and Stark H.
  TITLE     Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for
            Activation
  JOURNAL   Cell 170 (4), 701-713 (2017)
   PUBMED   28781166
REFERENCE   2  (bases 1 to 1656)
  AUTHORS   Schutze T, Ulrich AK, Apelt L, Will CL, Bartlick N, Seeger M, Weber
            G, Luhrmann R, Stelzl U and Wahl MC.
  TITLE     Multiple protein-protein interactions converging on the Prp38
            protein during activation of the human spliceosome
  JOURNAL   RNA 22 (2), 265-277 (2016)
   PUBMED   26673105
REFERENCE   3  (bases 1 to 1656)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474008.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001060413.1, XM_216475.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q34"
     gene            1..1656
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /note="pre-mRNA processing factor 38A"
                     /db_xref="GeneID:298374"
                     /db_xref="RGD:1311129"
     exon            1..332
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /inference="alignment:Splign:2.1.0"
     CDS             203..1141
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /note="PRP38 pre-mRNA processing factor 38 domain
                     containing A"
                     /codon_start=1
                     /product="pre-mRNA-splicing factor 38A"
                     /protein_id="NP_001100142.1"
                     /db_xref="GeneID:298374"
                     /db_xref="RGD:1311129"
                     /translation="MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTA
                     ELVVDKAMELKFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRML
                     GALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDI
                     ILPRLQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYR
                     DLDKPRRSPALRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHR
                     SRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE"
     exon            333..492
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /inference="alignment:Splign:2.1.0"
     exon            493..614
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /inference="alignment:Splign:2.1.0"
     exon            615..700
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /inference="alignment:Splign:2.1.0"
     exon            701..811
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /inference="alignment:Splign:2.1.0"
     exon            812..924
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /inference="alignment:Splign:2.1.0"
     exon            925..951
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1049
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1098
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1656
                     /gene="Prpf38a"
                     /gene_synonym="RGD1311129"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttcagccctc tctgaggaag gttgtgcgta gtgtccggaa agagttctga gccacagctt
       61 ccggtacaaa gctagtcgct ttccgcggtt cgaaggaatt ccttaaggtt tccctagcct
      121 ctgctagtct ttttcttctt cttttttaat ctggatgtga cgtattaagc aagccgacgg
      181 aaatagttga aagcgttcta aaatggcgaa ccgtacagtg aaggatgccc acagcatcca
      241 tggcaccaat cctcagtatc tggtggagaa gatcatccgg acacgaattt atgaatcaaa
      301 gtactggaaa gaagagtgtt ttggacttac agctgaactt gtagtcgaca aagccatgga
      361 gttgaagttt gtgggtggtg tgtatggtgg aaacataaag ccaactccat ttctatgttt
      421 aaccttgaag atgcttcaga ttcaacctga aaaagatatc attgttgagt tcataaaaaa
      481 tgaagatttc aagtatgtcc ggatgttagg ggccctttat atgaggctga caggaactgc
      541 aattgattgc tacaagtact tggagccttt gtacaatgac taccgaaaaa tcaagagcca
      601 gaacagaaat ggagagtttg aactgatgca tgtagatgag ttcattgatg aactactgca
      661 cagtgagcga gtctgtgata tcattttgcc tcggctacag aaacggtatg tgctggagga
      721 agctgagcag ctggagcctc gagtcagcgc tctagaagag gacatggatg acgtggagtc
      781 tagtgaggaa gaagaggagg aagatgagaa gttggaaaga gtaccatcac ctgaccaccg
      841 acgaagaagc taccgagact tggacaagcc aagacgctca cctgcactgc gctacaggag
      901 gagccggagc cgttctccca gaaggcggag tagatctcct aaaagaagaa gtccttctcc
      961 tcgacgagaa aggcatagga gcaagagtcc acgacgccat cgaagcaggt ccagagacag
     1021 acgacacaga tcccgctcta aatccccagg tcaccaccgt agtcacagac atagaagcca
     1081 ctcaaagtct cctgaaaggt ctaaaaagag ccacaagaag agccggagag gaaatgagta
     1141 atggattcat cttgatctca gccctgatga cctgtgggtg tgacagtgtc tgtttaagtg
     1201 gaatgatcag gatctcctct tcaggcagct atgagtattt ggggtttttc aaaatcaact
     1261 tgttttgttg ggctttgttt ttgttttaat attacagagg tgctaagttt tgtatctctt
     1321 tggattataa tcagcagctt tgaagagtgt ttttgatcaa atcaaggtca ggttttggcc
     1381 taaccaacta tggctataca tacttaacag gatcaagaag acctgggaat tggagaggtt
     1441 tcctgagaat aaaaagatgt gatcctttta tttgtaatta aacctcacac agttttcatt
     1501 tttctctgtt ttttgttgtt ttgtttattc tatatgatta gctgctttgc gaatcctctg
     1561 gtttaggctg ctgctgtgta aacacccagc taataaagca cattaattcc taacttctca
     1621 atacgcacag acagcagcag tggcaataaa catgga
//
