LOCUS       NM_001412323            4400 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus prospero homeobox 2 (Prox2), transcript variant
            2, mRNA.
ACCESSION   NM_001412323
VERSION     NM_001412323.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4400)
  AUTHORS   Galeeva,A., Treuter,E., Tomarev,S. and Pelto-Huikko,M.
  TITLE     A prospero-related homeobox gene Prox-1 is expressed during
            postnatal brain development as well as in the adult rodent brain
  JOURNAL   Neuroscience 146 (2), 604-616 (2007)
   PUBMED   17368742
  REMARK    GeneRIF: The prominent but limited distribution of Prox-1 in the
            brain suggests its potentially important role during postnatal
            brain development.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760389
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               JAXUCZ010000006.1  110489540-110489639 c
            101-800             JAXUCZ010000006.1  110484448-110485147 c
            801-2268            JAXUCZ010000006.1  110471871-110473338 c
            2269-2376           JAXUCZ010000006.1  110466495-110466602 c
            2377-2571           JAXUCZ010000006.1  110464692-110464886 c
            2572-4400           JAXUCZ010000006.1  110462456-110464284 c
FEATURES             Location/Qualifiers
     source          1..4400
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q31"
     gene            1..4400
                     /gene="Prox2"
                     /gene_synonym="RGD1310315"
                     /note="prospero homeobox 2"
                     /db_xref="GeneID:314319"
                     /db_xref="RGD:1310315"
     exon            1..100
                     /gene="Prox2"
                     /gene_synonym="RGD1310315"
                     /inference="alignment:Splign:2.1.0"
     exon            101..800
                     /gene="Prox2"
                     /gene_synonym="RGD1310315"
                     /inference="alignment:Splign:2.1.0"
     exon            801..2268
                     /gene="Prox2"
                     /gene_synonym="RGD1310315"
                     /inference="alignment:Splign:2.1.0"
     CDS             976..2757
                     /gene="Prox2"
                     /gene_synonym="RGD1310315"
                     /codon_start=1
                     /product="prospero homeobox protein 2"
                     /protein_id="NP_001399252.1"
                     /db_xref="GeneID:314319"
                     /db_xref="RGD:1310315"
                     /translation="MDPPAVLLSPQSQTCTHLAETCMGQERSPPTAEVGSDSFFPSGQ
                     LPSSSLTDADWFWDEHIQAKRARVETIVRGMCLSPSSLVSGRARESSRCPEKVRERKR
                     KQSLPMHQGPLKSSPAWDRGPKKGGTRVKEQLHLLKQQLRHLQEHVLQATEPRAPAQS
                     PGGTESRSSLGAKARNTFPYSAWAVESKPHQSSSKDIGGAVKPGAAEVLQQSEEPVFC
                     PSGPRALVETLRKELSRAVSQAVDSVLQQVLLDPQSLLPRQDGSCQGLASEGRSQPSP
                     PGRSAYKDPLALATLPRKVQPQAGVPLGNSTLARPLDSPICPVSPRGVPRSYQSPLSN
                     CPLTTVPSHIWENQILSQLLGRGPDGHWSGSPSQDASHQSHTSPESAQQPWGLSQQRL
                     PLSFTPVHLESRPLLPAAVKMEQSALQGVADSLPFSSVHIQEGLSPGHLKKAKLMFFF
                     TRYPSSSLLKAYFPDVQFNRCITSQMIKWFSNFREFYYIQMEKYARQAVSDGVTNAQA
                     LAVLRDSELFRVLNTHYNKGNDFEVPECFLQIATLTLQEFFRAVSTGKDSDPSWKKPI
                     YKIISKLDSDIPEILKSSSYSQGLFPS"
     exon            2269..2376
                     /gene="Prox2"
                     /gene_synonym="RGD1310315"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2571
                     /gene="Prox2"
                     /gene_synonym="RGD1310315"
                     /inference="alignment:Splign:2.1.0"
     exon            2572..4400
                     /gene="Prox2"
                     /gene_synonym="RGD1310315"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaccactaa ccgtgttggg tggcgggtgg tgagccgggc tagtatcatt agcggtccca
       61 gcgctgggga atctgtggct ctaagagcgg gctagcttgg ggtgaagtgg agaagacgga
      121 aaattctggg gtgatggtct gggtgtaggc cagttctcct cagctctatc agacataggc
      181 ctatcagcaa gcatccagta tcctctactg ctggggcagg cctcacggac tgttcttcct
      241 gagatctgag gagattttgg tgcaagatag aattcagacc cctgagattg ctggaggggt
      301 ctgaagaaag gtgatcactt tggaggcgtc tcacaacgga acttggaggc agaggtcagg
      361 agctgacaga gcagtggggg aagctgagca atcccggctc caaaccttca aagggctctg
      421 aaaattctta gcaaggacag ggaagatggc atcttgagaa accctctgag ctgggctttc
      481 agagaacctg atttgccacg gagggaggtg ggaaatgaca ggggtcagcc aaccagcttg
      541 ggggctccaa tttgcatatt cataagcccc ccttgctggt tggctgtgct tagcagccca
      601 ctgggcccca gtagggttgg gtctgtcaga tagtgacttg tattgagaag agacaggagg
      661 ctcccctcac ccagccacag cacctggctg acttggggag ggagaaagga aaccaaaatc
      721 acttcctgac cctcgctctg tttgcccaag gctggtgaag acactaatgg agaacagacc
      781 tccctgagaa cttcttctca gagtctgacc gagagagtcc tttggcctgg ccctcttgaa
      841 tcccagaagc agctgattct cacccttctg tgtgtgaaga agacccttca gcatggtcta
      901 gcccacctcc cgctgctcga tttagcaggg ctctcctttc tgggagctct ccacaggcac
      961 ccggagaggc aggtcatgga tccacctgct gtcttgcttt ctcctcagtc tcagacctgc
     1021 acccacctgg cagaaacatg catgggacag gagaggagcc cacccaccgc agaagtgggc
     1081 agtgactcct tctttcccag tggtcagttg cccagctcca gcctcactga tgccgattgg
     1141 ttttgggatg aacacatcca ggcaaagagg gccagagtag agaccattgt ccgaggcatg
     1201 tgtctctctc cgagttcgtt ggtgtcaggc agagccaggg agagctcacg ctgtccagaa
     1261 aaggtccggg agaggaagag aaagcagagt cttccaatgc accaaggtcc cctgaaatct
     1321 agccctgcct gggatcgagg gcccaagaag ggggggaccc gggtgaaaga acagcttcat
     1381 ctactgaagc aacagctaag acatttgcag gagcatgtcc tacaggccac tgagcccaga
     1441 gcaccagcac agagcccagg aggtactgag tcaagaagct ctctgggagc caaggcgagg
     1501 aacaccttcc catatagcgc ctgggccgtg gagagcaaac ctcaccagag ttctagcaag
     1561 gacattggtg gagcagtcaa gcccggagcc gctgaagttc tacagcagtc agaggagcct
     1621 gtgttctgtc cttccggccc acgggctcta gtggagactc tgaggaaaga actcagcagg
     1681 gctgtatccc aggctgtgga ctcagtatta caacaggtgc tacttgaccc acagagcctg
     1741 ctcccgcggc aggacgggag ctgccagggg ctggcatcag agggcagaag ccagccttca
     1801 cctccaggga gaagtgccta taaggaccca cttgctcttg ccaccctgcc caggaaggtc
     1861 cagccacaag ccggggttcc cttgggcaat tcaacactgg ctaggcctct agattctcct
     1921 atatgtcctg tctctccaag aggagttccc agatcatatc agagtcccct atcaaattgt
     1981 cccttgacaa ctgtaccttc ccacatctgg gaaaaccaga ttcttagcca gcttctgggt
     2041 cgtgggcctg atggccattg gagtggcagt ccttcccagg atgcatctca ccaaagtcat
     2101 acctccccag agtctgccca gcaaccctgg gggttgagcc agcagcgcct ccccctgtct
     2161 ttcacccctg tgcacctgga aagccgtcct ctcctgccgg cggcggtgaa gatggagcag
     2221 agcgcgctgc agggcgtggc cgactcactt cctttctctt ccgtccacat ccaggaaggc
     2281 ctgagccctg gtcacctgaa gaaggccaag ctaatgtttt tcttcacgcg gtatcccagc
     2341 tccagcctcc tgaaagctta cttccctgat gttcagttca atcgatgcat cacctcccag
     2401 atgatcaagt ggtttagcaa tttccgtgag ttttactaca tccagatgga gaagtatgcc
     2461 cggcaagcgg tttcagacgg tgtcacgaat gcccaagcgc tagcagtcct ccgagactca
     2521 gagctttttc gagttctcaa tacacactat aacaaaggga atgactttga ggtcccagaa
     2581 tgcttcttgc aaattgccac cttgacatta caggagttct tcagggctgt ctccacaggg
     2641 aaagattcag atccttcctg gaagaaaccc atttacaaaa ttatttcaaa actggacagt
     2701 gacatcccgg agatactcaa atcttccagc tattcccaag gactgtttcc aagttaagat
     2761 ccaacaaaat gaggtcaagt atgatagcac aggcctttga ttccaagatg ggaggtggag
     2821 gcaggaggat caggaactta aggacagaca gtcttcgcta caaaaacaaa catcaaacaa
     2881 aatgagtaga caggcccagg atggcccaag atttgtcata aatggcagtt tagctgtagt
     2941 cacataagag agcacaagag gaacttgagt aggtacaact gccattttga atactcgttt
     3001 tcttgtccag aatcatcaga taaccacagt gcatcaacta agcctatcag tgtgttcgca
     3061 gtcctttggg aaaggaacac acatttggga tcagaagact taaagtcatt aagagctgca
     3121 acactgataa tctcctggta tttctataac tctggaagga ggcttatagc caagtggtgg
     3181 tggtaaacag ctttaatccc tgcactagag aggcagaggc aggtggatct ctgtgagttg
     3241 gaggccagcc tggtctacag agtgagttcc aggacagcca aggcaacact gagaaacact
     3301 gtctcaaaaa accaaaaacc cggggctgga gagatggctc agcggttaag agcacccaac
     3361 tgctcttcca gaagtcctga gttcaattcc cagcaaccac atggtggctc acaaccatct
     3421 gtaaagagat ccgatttcct cttctggtgt atctgaagac agctacagtg tacttatata
     3481 taataaatga ataaataaat ttaaaaaaac ccccaaaaac cccaagaaaa tttgaagtgt
     3541 gggtacctca ttgatcctta tgccaggata cagaatcggt caggactgtg gaggaagcaa
     3601 tgactgtgta tgctggactc atgctgtaac tcagggaaaa tccataccaa caggacaccc
     3661 acagagtggc actgccattc gaccaggttt gcactctgga gtgcgtcacc atccaccgct
     3721 gttgcttgca tctgtctgct ggcacactgt gtcagctgac agttctacat cctacttgac
     3781 ctatgtgctg atgccccaac tgcctatacg cacaaaatat atataaataa aaatggaact
     3841 tcatgatgag gaggccagaa ggggccctgg agaccatctg atccaccttg tgtaacctgt
     3901 ggaggaaaca ggctagcata cactttgtag ggcctcacat tccatgaatg gcagggctgg
     3961 gacaaaggca aaaatggaga ttttcctact ttgaaatgat tacagtctat gattgaactc
     4021 gcacggatga gcaaatgaca ttcatattcc ccccatgggt ccgacacaat tgtgacagac
     4081 tctgagcacc aggcaaggca cacataaact ggaacaactg tgtcttccag tcagaaccaa
     4141 gccggtaaca ctgctggagg agagcaggat ggagtagcct tcaggattcc cagtgctaag
     4201 tgagtgcaac tgtgcctgca atagctcccc tccctgccct cagcccagaa cgattttcac
     4261 atcgagctcc tctgccttca ggacttgatg ggtcgtggct gtggctactg ctagatatgt
     4321 cagactacac caatatgaac aaggcctttc ctctgaatct tctgttcaaa tagtggagag
     4381 aagaaacaac acatacttaa
//
