LOCUS       NM_001014153            2325 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus protein arginine methyltransferase 7 (Prmt7),
            mRNA.
ACCESSION   NM_001014153 XM_341682
VERSION     NM_001014153.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2325)
  AUTHORS   Gayatri,S. and Bedford,M.T.
  TITLE     Readers of histone methylarginine marks
  JOURNAL   Biochim Biophys Acta 1839 (8), 702-710 (2014)
   PUBMED   24583552
  REMARK    Review article
REFERENCE   2  (bases 1 to 2325)
  AUTHORS   Di Lorenzo,A. and Bedford,M.T.
  TITLE     Histone arginine methylation
  JOURNAL   FEBS Lett 585 (13), 2024-2031 (2011)
   PUBMED   21074527
  REMARK    Review article
REFERENCE   3  (bases 1 to 2325)
  AUTHORS   Wang,H., Straubinger,R.M., Aletta,J.M., Cao,J., Duan,X., Yu,H. and
            Qu,J.
  TITLE     Accurate localization and relative quantification of arginine
            methylation using nanoflow liquid chromatography coupled to
            electron transfer dissociation and orbitrap mass spectrometry
  JOURNAL   J Am Soc Mass Spectrom 20 (3), 507-519 (2009)
   PUBMED   19110445
REFERENCE   4  (bases 1 to 2325)
  AUTHORS   Gonsalvez,G.B., Tian,L., Ospina,J.K., Boisvert,F.M., Lamond,A.I.
            and Matera,A.G.
  TITLE     Two distinct arginine methyltransferases are required for
            biogenesis of Sm-class ribonucleoproteins
  JOURNAL   J Cell Biol 178 (5), 733-740 (2007)
   PUBMED   17709427
REFERENCE   5  (bases 1 to 2325)
  AUTHORS   Jelinic,P., Stehle,J.C. and Shaw,P.
  TITLE     The testis-specific factor CTCFL cooperates with the protein
            methyltransferase PRMT7 in H19 imprinting control region
            methylation
  JOURNAL   PLoS Biol 4 (11), e355 (2006)
   PUBMED   17048991
REFERENCE   6  (bases 1 to 2325)
  AUTHORS   Lee,J.H., Cook,J.R., Yang,Z.H., Mirochnitchenko,O., Gunderson,S.I.,
            Felix,A.M., Herth,N., Hoffmann,R. and Pestka,S.
  TITLE     PRMT7, a new protein arginine methyltransferase that synthesizes
            symmetric dimethylarginine
  JOURNAL   J Biol Chem 280 (5), 3656-3664 (2005)
   PUBMED   15494416
REFERENCE   7  (bases 1 to 2325)
  AUTHORS   Miranda,T.B., Miranda,M., Frankel,A. and Clarke,S.
  TITLE     PRMT7 is a member of the protein arginine methyltransferase family
            with a distinct substrate specificity
  JOURNAL   J Biol Chem 279 (22), 22902-22907 (2004)
   PUBMED   15044439
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085121.1.
            
            On Apr 1, 2005 this sequence version replaced XM_341682.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085121.1, SRR8487227.289380.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2325
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..2325
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /note="protein arginine methyltransferase 7"
                     /db_xref="GeneID:361402"
                     /db_xref="RGD:1304869"
     exon            1..78
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            79..273
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..2260
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /EC_number="2.1.1.321"
                     /note="histone-arginine N-methyltransferase PRMT7; [Myelin
                     basic protein]-arginine N-methyltransferase PRMT7"
                     /codon_start=1
                     /product="protein arginine N-methyltransferase 7"
                     /protein_id="NP_001014175.1"
                     /db_xref="GeneID:361402"
                     /db_xref="RGD:1304869"
                     /translation="MKVFCGRANPTTGSLEWLEEDEHYDYHQEIARSSYADMLHDKDR
                     NIKYYQGIRAAVSRVKDKGQKALVLDIGTGTGLLSMMAVTAGADFCYAVEVFKPMAEA
                     AVKIVEKNGFSDKIKVINKHSTEVTVGPDGDLPCRANILVTELFDTELIGEGALPSYE
                     HAHKHLVQEDCEAVPHRATVYAQLVESKRMWSWNKLFPVRVQTGLGEQLIIPPSELER
                     CPGAPSVYDIQLNQVSPADFTVLSDVLPMFSVDFSKQVSSSAACHSKQFVPLASGQAQ
                     VVLSWWDIEMDPEGKIKCTMAPFWAQTDPQELQWRDHWMQCVYFLPQEEPIMQGSPRC
                     LAAHHDDYCVWYSLQRTSPDENNSAYQVRPVCDCQAHLLWNRPRFGEINDQDRTDHYA
                     RALRTMLMPGSICLCVSDGSLLSVLAHHLGAEQVFTVESSVASYRLMKRIFKVNHLED
                     KITVINKRPELLTSADLEGKKVSLLLGEPFFTTSLLPWHNLYFWYVRTSVDQHLAPGA
                     VVMPQAASLHAVIVEFRDLWRIRSPCGDCEGFDVHIMDDMIKHSLDFRESREAEPQPL
                     WEYPCRSLSEPRQILTFDFQQPIPQQPMQSRGVMELRRPGKSHGAVLWMEYQLTPDST
                     VSTGLMNPAEDKGDCCWNPHCKQAVYFLSATLDPSAPLDGPQSVSYAVEFHPLTGDIT
                     MEFRLADDTLN"
     exon            274..310
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            311..460
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            461..569
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            570..682
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            683..924
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1105
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1233
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            1234..1369
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1453
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1501
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1591
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            1592..1753
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            1754..1828
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            1829..1989
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            1990..2086
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
     exon            2087..2305
                     /gene="Prmt7"
                     /gene_synonym="RGD1304869"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcaccgacg ccccgccccc agtgggtgag gcaaaatggc cgcggaattt gcggcgagtg
       61 gagtgcttcc cacagcgggc attataattg attaggtttc tgatatccag ttctagtcct
      121 aagaagtaaa ttgataagcc cacatttctg tgcaaacact gaggagccaa ttggcgccat
      181 gaaggtcttc tgtggccgtg ccaatccaac cacgggatcc ctggaatggc tggaggagga
      241 tgaacactat gattaccacc aagaaattgc caggtcatcc tatgccgata tgctacacga
      301 caaagacaga aatataaaat attaccaggg tatccgggca gctgtgagca gagtgaaaga
      361 caaaggacag aaggccttgg ttcttgacat tggcactggc acaggcctct tatcaatgat
      421 ggcagttacc gcaggggctg acttctgcta tgctgttgag gtttttaagc caatggctga
      481 ggctgctgtg aagattgtgg agaaaaatgg cttcagtgat aagattaaag taattaacaa
      541 gcattccact gaggtgacgg ttggaccaga tggtgacttg ccatgccgtg ctaacattct
      601 ggttacggag ctgtttgaca cagagctgat tggggaggga gcactgccct cttatgagca
      661 cgcacacaag catcttgtac aggaagactg tgaagcagtg cctcacaggg cgactgtcta
      721 tgcccagttg gtggagtcca aaaggatgtg gtcatggaac aagctgtttc ctgtccgggt
      781 ccagactggt cttggagagc agcttatcat tcctccctca gaattggaga ggtgtcctgg
      841 tgcaccttcc gtctatgaca ttcagctgaa ccaggtgtca cctgctgact tcactgtcct
      901 cagtgatgtg ctgccaatgt tcagcgtgga cttcagcaag caagtcagca gctcggcagc
      961 gtgccatagc aagcagtttg tccctctggc atctggccaa gcacaggtgg ttctctcctg
     1021 gtgggacata gaaatggacc ctgagggcaa gatcaagtgc accatggcac ccttttgggc
     1081 acagacagat ccacaggaac ttcagtggcg ggaccactgg atgcagtgtg tgtacttcct
     1141 gccccaggag gagcccatta tgcagggctc accccgatgc ctggctgctc accatgatga
     1201 ctactgtgtg tggtacagcc ttcagagaac cagccctgat gagaataaca gtgcctacca
     1261 agttcgacct gtatgtgact gtcaggctca cctgctctgg aaccggccac ggtttggaga
     1321 gatcaatgat caggacagaa ctgatcacta tgcccgagcc ctgaggacta tgctgatgcc
     1381 aggtagcatc tgcctttgtg tgagtgacgg cagtctactc tctgtgttgg cccatcacct
     1441 tggagcagag caggtgttta cagtcgagag ttcagtagct tcctatagac tgatgaaaag
     1501 gatcttcaag gttaaccact tggaagataa aattaccgtc atcaataaac ggcctgagtt
     1561 gttgacatct gcagacctgg agggtaagaa ggtctccctc ctcctgggtg aacctttttt
     1621 caccaccagc ctgctaccat ggcacaacct gtacttctgg tatgtgcgca cctctgtgga
     1681 ccagcaccta gcgcctgggg ctgtggtgat gccccaggca gcctcactgc atgccgtgat
     1741 cgtggagttc agggacctgt ggcgaatccg gagtccttgt ggtgactgtg aagggtttga
     1801 cgtccacatc atggatgata tgatcaagca ctccctggat ttccgagaga gcagggaggc
     1861 agagccacag ccactgtggg aatacccctg cagaagcctc tcagagcctc gacagatcct
     1921 gacttttgat ttccagcagc ccatccccca gcagcctatg caatccaggg gcgtgatgga
     1981 actgaggagg cccgggaaga gccatggagc tgtcctgtgg atggaatacc agctgactcc
     2041 agatagcact gtcagcaccg gcctcatgaa ccctgcagag gacaaggggg actgctgctg
     2101 gaacccccac tgcaagcaag ctgtgtactt cctcagtgcc acactggatc ctagcgcgcc
     2161 tctggatggc cctcaatcag tcagctatgc tgtggagttt caccccctca ctggagacat
     2221 caccatggag tttaggcttg cagacgacac cttgaactga tctcttacag agaaataaaa
     2281 tggccaccag gctgcagact ctgaaaaaaa aaaaaaaaaa aaaaa
//
