LOCUS       NM_001024762            2141 bp    mRNA    linear   ROD 18-FEB-2025
DEFINITION  Rattus norvegicus DNA primase subunit 2 (Prim2), transcript variant
            3, mRNA.
ACCESSION   NM_001024762 XM_217375
VERSION     NM_001024762.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2141)
  AUTHORS   Popanda,O., Flohr,C., Dai,J.C., Hunzicker,A. and Thielmann,H.W.
  TITLE     A mutation in subunit B of the DNA polymerase alpha-primase complex
            from Novikoff hepatoma cells concomitant with a conformational
            change and abnormal catalytic properties of the DNA polymerase
            alpha-primase complex
  JOURNAL   Mol Carcinog 31 (4), 171-183 (2001)
   PUBMED   11536367
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC097454.1.
            
            On Jun 10, 2005 this sequence version replaced XM_217375.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097454.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2141
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q21"
     gene            1..2141
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /note="DNA primase subunit 2"
                     /db_xref="GeneID:301323"
                     /db_xref="RGD:631433"
     exon            1..143
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            144..206
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            207..313
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            314..476
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     CDS             323..1777
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /note="isoform 2 is encoded by transcript variant 3; DNA
                     primase large subunit; p58; DNA primase 58 kDa subunit;
                     DNA primase, p58 subunit; DNA polymerase alpha subunit III
                     (primase); primase, DNA, polypeptide 2; primase (DNA)
                     subunit 2"
                     /codon_start=1
                     /product="DNA primase large subunit isoform 2"
                     /protein_id="NP_001019933.1"
                     /db_xref="GeneID:301323"
                     /db_xref="RGD:631433"
                     /translation="MQFSGRTRKKLRLAGDQRNACYPHSLQFYLQPPTENISLTEFES
                     LAFDRVKLLKAIENLGVSYVKGTEQYQSKLEAEIRKLKFSYRENLEDEYEPRRRDHIS
                     HFILRLAYCQSEDLRRWFIQQEMDLLRFRFSILPKDKVQSFLKDTHLHFEAISDEEKT
                     LREQDIMASSPSLSGVRWESESVYKVPFADALDLFRGRKVYLEDGFAYVPLKDIVAII
                     LNEFRATLSKALALTARSLPAVQSDERLQPLLSHLSHSYTGQDYSTQKSTGKISLDQI
                     DSLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIKG
                     KMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCMKIILTNPPSQGDFHGCPFRHSDAE
                     LLKQKMQTYKIPASGISQVDDCGFSLNHPNQFFFESQRILTGGKDIKKEASHPETPQH
                     KPSTQKTKDATSALASLDSSLEMDLEGLEDYFSK"
     exon            477..580
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            581..660
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            661..781
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            782..877
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1015
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1083
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            1084..1156
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1342
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..1469
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1552
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
     exon            1553..2113
                     /gene="Prim2"
                     /gene_synonym="Pola3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttcgccccc caaccctgcc ttgggtaccg atccaacctg gcccctcaag tcaccggagg
       61 actatatata ccctcttcca ctgaggccag ccagtatagg ccagctaggg gcacaggatc
      121 cacaggcagg caacagagtc agggtgtaat cagggtgctg agaaggtcca gggagctggg
      181 gatccaagtc aagtcattgt tgcaagtctc tgtatttcct gggaagagaa agacaacaca
      241 aaggaggacc catcagcgca tctgtcttct gaaggctgcc agtatcttga attgaatcga
      301 cggttgtctt tcagtggtca agatgcagtt ctcaggaagg acccggaaga agctgagatt
      361 ggcaggtgac cagagaaacg cttgttaccc tcacagcctt cagttctatc tgcagccacc
      421 tactgaaaac atatcattga cagagtttga aagcttggct tttgatagag taaaattgct
      481 taaagcaatt gagaatcttg gtgtgagcta tgtgaaagga accgaacagt accagagtaa
      541 actggaggct gagattcgaa agctcaagtt ttcgtacagg gagaacctgg aggatgagta
      601 cgagcctcgg aggagggacc acatctccca cttcatcctg cgcctcgctt actgccagtc
      661 ggaagatctt agacggtggt ttattcaaca ggagatggat ctgcttcggt tccgattcag
      721 tattttaccc aaggataaag tccagagttt cttgaaggat actcacttgc attttgaggc
      781 tatcagtgat gaggagaaga cccttcggga acaggatatc atggcgtcct ctcccagcct
      841 aagtggggtc aggtgggaat cggagtcagt gtataaggtc ccctttgctg acgctctgga
      901 cctgttcaga ggaaggaaag tctacttgga agacggcttt gcttatgtgc cacttaagga
      961 cattgtggcc attatcctga acgagtttag agccacgctg tctaaggcct tggcactaac
     1021 agccaggtcc ctgcctgctg tgcagtccga tgaacgactt cagcctctgc tcagccacct
     1081 cagtcattct tacaccggcc aagattatag tacccagaag agcaccggga agatttcctt
     1141 agatcagatt gattcgcttt caacaaaatc cttcccacct tgcatgcgtc agctgcacaa
     1201 ggcgctgagg gaaaaccacc atcttcgtca tggaggccgg atgcagtatg gcctgttcct
     1261 caagggcatt gggctaacgt tggagcaagc attgcagttc tggaagcaag agtttatcaa
     1321 aggaaagatg gacccagaca agtttgataa aggttactct tacaatatcc gacatagctt
     1381 tggaaaggaa ggcaagagga cagactatac gccattcagt tgcatgaaga ttatcctgac
     1441 caacccacca agccaggggg atttccatgg gtgcccattc cgtcacagtg atgcagagct
     1501 gctgaagcag aagatgcaga cctacaagat ccctgcctcg gggatcagcc aggtggacga
     1561 ttgtggcttt tctttgaatc atccgaatca gttctttttt gagagccagc gaatcctaac
     1621 tggtggcaaa gatatcaaga aggaagcaag ccacccagaa acgcctcagc acaaacccag
     1681 cacccagaag accaaggatg ccacgtctgc tctggcctct ctagattcct ccctggaaat
     1741 ggatctggag gggctagaag actactttag taaatgacgt ggcccctgga gcaactggag
     1801 caaatacatt cctgtttgaa aggtttgcct ttgtaaacct ttctcttcct acccacgcat
     1861 gctcacacat gtactgggaa agcaggcttg cttccacctt acttttgaca gaatgaaaaa
     1921 ggaagagttc ctatggaaac ctttcattga atatttcgtt ttgaatcctg ttccagaaaa
     1981 tttaaaacag tactcaggga ctaaaatcct caagcagcaa tacaactaaa actaactttt
     2041 aaagtttcac ctagttttgg ccaagtcttc ttttggatcg attttgctaa taaacaacat
     2101 gtatatgact ataaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
