LOCUS       NM_181440                867 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus proline rich protein HaeIII subfamily 1 (Prh1),
            mRNA.
ACCESSION   NM_181440 XM_039108868 XM_579719
VERSION     NM_181440.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   2  (bases 1 to 867)
  AUTHORS   Ten Hagen,K.G., Beres,T.M., Szpirer,J., Szpirer,C. and Tabak,L.A.
  TITLE     Chromosomal organization and expression analysis of two distinct
            genes encoding glutamine/glutamic acid-rich proteins
  JOURNAL   Biochem J 324 (Pt 1) (Pt 1), 177-184 (1997)
   PUBMED   9164854
REFERENCE   3  (bases 1 to 867)
  AUTHORS   Cooper,L.F. and Tabak,L.A.
  TITLE     Characterization of the gene encoding the salivary Gln/Glu-rich
            C-terminal variant A protein
  JOURNAL   Gene 106 (2), 261-266 (1991)
   PUBMED   1937054
REFERENCE   4  (bases 1 to 867)
  AUTHORS   Cooper,L.F., Elia,D.M. and Tabak,L.A.
  TITLE     Secretagogue-coupled changes in the expression of
            glutamine/glutamic acid-rich proteins (GRPs). Isoproterenol induces
            changes in GRP transcript expression and changes in isoforms
            secreted
  JOURNAL   J Biol Chem 266 (6), 3532-3539 (1991)
   PUBMED   1995617
REFERENCE   5  (bases 1 to 867)
  AUTHORS   Mirels,L., Bedi,G.S., Dickinson,D.P., Gross,K.W. and Tabak,L.A.
  TITLE     Molecular characterization of glutamic acid/glutamine-rich
            secretory proteins from rat submandibular glands
  JOURNAL   J Biol Chem 262 (15), 7289-7297 (1987)
   PUBMED   2438276
REFERENCE   6  (bases 1 to 867)
  AUTHORS   Heinrich,G. and Habener,J.F.
  TITLE     Genes encoding proteins with homologous contiguous repeat sequences
            are highly expressed in the serous cells of the rat submandibular
            gland
  JOURNAL   J Biol Chem 262 (11), 5262-5270 (1987)
   PUBMED   3558393
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On or before Jul 18, 2022 this sequence version replaced
            XM_039108868.1, NM_181440.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M17703.2, J02730.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN16676788,
                                           SAMN16676789 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-96                JAXUCZ010000004.1  168275152-168275247
            97-132              JAXUCZ010000004.1  168276108-168276143
            133-773             JAXUCZ010000004.1  168277044-168277684
            774-867             JAXUCZ010000004.1  168278918-168279011
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..867
                     /gene="Prh1"
                     /gene_synonym="CRP; GRP-Ca; Grpca; Grpca_m"
                     /note="proline rich protein HaeIII subfamily 1"
                     /db_xref="GeneID:120093082"
                     /db_xref="RGD:619775"
     exon            1..96
                     /gene="Prh1"
                     /gene_synonym="CRP; GRP-Ca; Grpca; Grpca_m"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..773
                     /gene="Prh1"
                     /gene_synonym="CRP; GRP-Ca; Grpca; Grpca_m"
                     /note="glutamine/glutamic acid-rich protein; contiguous
                     repeat polypeptide; submandibular gland secretory Glx-rich
                     protein CA; glutamine/glutamic acid-rich protein GRP-Ca;
                     glutamine/glutamic acid-rich protein A, mapped;
                     rCG29588-like"
                     /codon_start=1
                     /product="submandibular gland secretory Glx-rich protein
                     CA precursor"
                     /protein_id="NP_852105.2"
                     /db_xref="GeneID:120093082"
                     /db_xref="RGD:619775"
                     /translation="MLVVLLTAALLALSSAQGTDEEVNNAETSDVPADSEQQPVDSGS
                     DPPSADADAENVQEGESAPPANEEPPATSGSEEEQQQQEPTQAENQEPPATSGSEEEQ
                     QQQEPTQAENQEPPATSGSEEEQQQQEPTQAENQEPPATSGSEEEQQQQESTQAENQE
                     PSDSAGEGQETQPEEGNVESPPSSPENSQEQPQQTNPEEKPPAPKTQDEPQHDSGRPK
                     KPLLPFIANLIPERIRKLLARSPLARRF"
     exon            97..132
                     /gene="Prh1"
                     /gene_synonym="CRP; GRP-Ca; Grpca; Grpca_m"
                     /inference="alignment:Splign:2.1.0"
     exon            133..773
                     /gene="Prh1"
                     /gene_synonym="CRP; GRP-Ca; Grpca; Grpca_m"
                     /inference="alignment:Splign:2.1.0"
     exon            774..867
                     /gene="Prh1"
                     /gene_synonym="CRP; GRP-Ca; Grpca; Grpca_m"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagttgggag aaagtccata gactcctcca agatgcttgt ggtcctgctc acagcagcct
       61 tgctggctct gagctcagct cagggcacgg atgaagaggt caacaatgct gagaccagtg
      121 atgtaccagc agattctgaa caacaacccg tggactcggg ttcagatcca ccttctgctg
      181 atgcagatgc agagaatgtt caagagggtg aatcagcccc accagcaaat gaagagcctc
      241 ctgccacctc tgggagtgaa gaggaacagc agcagcagga acccacacag gcagagaatc
      301 aagagcctcc tgccacctct gggagtgaag aggaacagca gcagcaggaa cccacacagg
      361 cagagaatca agagcctcct gccacctctg ggagtgaaga ggaacagcag cagcaggaac
      421 ccacacaggc agagaatcaa gagcctcctg ccacctctgg gagtgaagag gaacagcagc
      481 agcaggaatc cacacaggca gagaatcaag agccttctga ctctgctggg gaaggacagg
      541 aaactcaacc tgaggaagga aatgtagagt cacctccctc ttctcctgaa aactcacaag
      601 aacaaccaca gcaaacaaat ccagaggaga aaccgcctgc tcctaagact caggatgaac
      661 cacagcacga cagcggtcgt ccaaagaagc ccctccttcc ttttatcgct aatttaatac
      721 cagaaagaat tcggaaatta ttagctcgca gtccattagc cagaagattt tagagagtac
      781 ctgagaagat tatgaccttc agatgtgtag gtcaacaaat cactgttgat tgtctataat
      841 attccaataa aaattttcag catgcaa
//
