LOCUS       XM_039105139            3509 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus
            phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange
            factor 1 (Prex1), transcript variant X2, mRNA.
ACCESSION   XM_039105139
VERSION     XM_039105139.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3509
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3509
                     /gene="Prex1"
                     /gene_synonym="RGD1306534"
                     /note="phosphatidylinositol-3,4,5-trisphosphate-dependent
                     Rac exchange factor 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 9 ESTs, 1 Protein, and
                     99% coverage of the annotated genomic feature by RNAseq
                     alignments, including 89 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:311647"
                     /db_xref="RGD:1306534"
     CDS             404..3121
                     /gene="Prex1"
                     /gene_synonym="RGD1306534"
                     /codon_start=1
                     /product="phosphatidylinositol
                     3,4,5-trisphosphate-dependent Rac exchanger 1 protein
                     isoform X2"
                     /protein_id="XP_038961067.1"
                     /db_xref="GeneID:311647"
                     /db_xref="RGD:1306534"
                     /translation="MMAPLKFWSTSRLSAAAGRRPWHSPCDWSSDSGSFQGLYQWVYH
                     SHEDAQQARASQGAPDEDPQEDDSVLPLLSLGPQLSLHEDSAVVSLTLDNVHLEHGVV
                     YEYVSTAGAKCHVLEKIVEPRGCFRLAAKILEAFAEDDSLFVQNCGRLMAMGSAIITM
                     SHYEFHNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEDHPLCGLDFCPTNC
                     HINFMEVSYPKTTPSVGRSFSIRFGRKPSLIGLDPEQGHLNPMAYTQHCITTMAAPSW
                     KCAPAVDGDSQSQGLIDSIFVSASGALSQQERGLSFLLKQEDREIQDAYLQLFTKLDV
                     ALKEMKQYVTQINRLLSTITEPTSAAPCDPPLVEETSSSPPASEESEVDRTDHGGIKK
                     VCFKVSEDEQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDETGSGDEL
                     PCDIRIPSDKQDKLHGCLEHLFNQVDSIHALLKGPVMSRAFEETRHFPMEHSWQEFKQ
                     KEECTVRGRNLIQISIQEDPWNLPSSIRTLVDNIQRYVEDGKNQLLLALLKCTDTELQ
                     LRRDAVFCQALVAAVCTFSEQLLAALDYRYNNNGEYEESSRDASRKWLEQVAATGVLL
                     HWQSLLAPATVKEERTMLEDIWVTLSELDNVTFSFKQLDENSVANTNVFYHIEGSRQA
                     LKVVFYLDGFHFSRLPSRLEGGASLRLHTVLFTKALENVEGPSPPGSQAAEDLQQEIN
                     AQSLEKVQQYYRRLRAFYLERSNLPTDATTTAVKIDQLIRPINALDELYRLMKSFVHP
                     KAGAGGSLGAGLVPVSSELCYRLGACQITMCGTGMQRSTLSVSLEQAAILARSHGLLP
                     KCVMQATDIMRKQGPRVEILAKNLRIKDPMPQGAPRLYRLCQPPVDGDL"
ORIGIN      
        1 cagatcccgc cgcaggagga tgactatggc ttcgatcttg aggagaagaa caaggcagtg
       61 gtggtgaagt ccgtgcagag gggttcgctg gctgagatgg ctggcctgca ggcggggagg
      121 aagatttact ccatcaacga ggacctggtg ttcctacggc ccttctctga ggtggagacc
      181 atccttaacc agtccttctg ctcccgccgc ccgctgcgcc tcctggtggc caccaaggcc
      241 aaagagacca tcaaaatccc tgaccaccca gaggccctgt ccttccagat tcgaggaaca
      301 gccccgccgt gtgtctttgc cgtgggcaga ggttctgagg ctgtggctgc cgggctctgc
      361 gcaggccaat gcatcctgaa agtcaacggc aacagcgtgg caaatgatgg cgcccttgaa
      421 gttctggagc acttccaggc tttccgcagc cgcagggagg aggccctggc actcaccatg
      481 cgactggtcc tctgacagtg gttcttttca gggcctttac cagtgggtct accacagcca
      541 cgaggacgcc cagcaggcga gagccagcca gggtgccccg gatgaggacc cccaggagga
      601 tgactcagtc ctgcccctgc tgtccctggg tccccagctg agcctgcacg aggacagcgc
      661 tgtggtcagc ctgacgctgg acaatgttca cttggagcac ggtgtggttt atgaatacgt
      721 gagcacagca ggagccaagt gtcacgtgct ggaaaagatc gtggagcccc gaggctgttt
      781 ccgcctggct gccaagatcc ttgaggcctt tgccgaggac gacagcctct tcgtgcagaa
      841 ctgtgggcgg ctcatggcca tgggcagcgc tatcatcacc atgtcccact acgagttcca
      901 caacatctgt gacaccaagc tggagagcat tggccagaga atcgcctgct accaggagtt
      961 tgcagcccag ctgaagagca gggtcagccc ccccttcaag caggcacccc tggaggacca
     1021 cccgctgtgt ggcctggact tctgccctac caactgccac atcaacttca tggaggtgtc
     1081 ctaccccaag accacccctt cagtgggcag gtccttcagc atccgctttg ggcgcaaacc
     1141 ctccctcatc ggccttgacc cagaacaagg ccacctgaac cccatggctt acacccagca
     1201 ctgtatcacc accatggctg ccccgtcctg gaagtgcgcg cctgctgtag atggggactc
     1261 tcaaagccaa ggtctcattg acagtatctt cgtgtcagcc agtggtgccc tgagccagca
     1321 agaacggggc ctgagctttc tgctcaagca ggaggaccgg gagatccagg acgcgtatct
     1381 gcagctcttc actaagctgg atgtggccct caaggagatg aagcagtatg tcacccagat
     1441 caacaggctg ctgtcaacca tcacagagcc cacgtcagct gcaccctgtg acccaccctt
     1501 ggtggaggag acctcatctt ccccaccggc cagtgaagag agcgaagtgg acaggactga
     1561 ccatggcggc atcaagaagg tgtgcttcaa ggtgtcagag gacgagcagg aagactcggg
     1621 ccacgacacc atgagctacc gagactccta tagtgagtgt aacagcaatc gtgactctgt
     1681 cctgtcctac accagcgtga gaagcaacag ttcgtacctg ggcagtgatg agacaggctc
     1741 aggggatgag ctgccctgtg acatacgcat cccatccgac aagcaggaca aacttcacgg
     1801 ctgcctggaa catctcttta accaggtgga ttccatccat gccctgctca aggggcctgt
     1861 gatgagcagg gcgtttgagg agaccaggca tttccccatg gagcacagct ggcaagagtt
     1921 caaacagaaa gaagaatgca cagtccgagg ccggaacttg atccagatca gcatccagga
     1981 ggacccttgg aacctaccca gctccatcag gaccctggta gacaacatcc agcgatatgt
     2041 ggaagatggg aagaaccagc tgcttctggc cctgctgaaa tgcacagaca cggagctgca
     2101 gctgcgcagg gatgctgtct tctgtcaggc cctggtggcc gccgtgtgca ccttctcgga
     2161 gcagctgctg gccgccctcg actaccgcta caacaacaac ggcgagtatg aagagagcag
     2221 cagagacgcc agccgcaagt ggctggagca ggtggcagcc accggtgtcc tgctgcactg
     2281 gcagtccctg ctggcaccag ccaccgtgaa agaggaacgg accatgctgg aggacatctg
     2341 ggtgacactg tcggagctgg acaatgtcac cttctccttt aagcagctgg atgagaattc
     2401 tgtggccaac accaacgtct tctaccacat tgagggcagc aggcaggcac tgaaggtagt
     2461 cttctacctc gatggcttcc acttctccag gctgccctct cgcctggagg gtggggccag
     2521 cctcaggctg cacaccgtgc tattcacaaa agctctggag aatgtggaag ggccgtcgcc
     2581 cccaggaagc caggctgcag aagatctgca gcaggagatc aatgcgcagt ccctggagaa
     2641 ggttcagcag tactatagaa ggctcagggc cttctacctg gagcggtcca acctccccac
     2701 agatgctacc accacagctg tgaagatcga ccagctgatc cgtcccatca acgccctgga
     2761 cgagctctac cgcctcatga agtccttcgt gcacccgaaa gctggtgctg gtgggagcct
     2821 aggtgccggc ctcgtccccg tctcctctga gctctgctac cgtctggggg cgtgtcagat
     2881 caccatgtgt ggcaccggca tgcagcggag caccctgagc gtgtccttgg aacaagcagc
     2941 catcttggct cggagccacg ggctgctgcc caagtgtgtt atgcaggcca cagacatcat
     3001 gcgcaagcag ggcccccgag tggagatcct ggcaaaaaac ctccgcatca aagacccaat
     3061 gccccaaggt gcaccacgcc tctaccgcct ctgccagcct ccggtggatg gagacctctg
     3121 aacaccgacc tgctccatgc tcagccactg cctctgcagc tgccatgtgg gaggacacgg
     3181 aggggctgca aggtgacccg aggcttctgc catagctgtg tcaagaccta cccagctgac
     3241 cctgccgcca ccgtccaggt caagcctctg cgagcataca ctgtctctgg accggcagat
     3301 cacggttggg ctggcagatt ctccatactt aacgcctgaa acctgagggc tgcttggggc
     3361 cccagagctc atgaatgtag cccggcctgg atgcctgcac tcacccaggt cccctacaca
     3421 gggaaaggtc acagggtccg gcgggtgaag gcctgcagac cccgctcctc agatggcaaa
     3481 gctgcacttt gaacctgggt tcctcccag
//
