LOCUS       NM_001009636            1151 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus PRELI domain containing 1 (Prelid1), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_001009636 XM_214431
VERSION     NM_001009636.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1151)
  AUTHORS   Potting C, Tatsuta T, Konig T, Haag M, Wai T, Aaltonen MJ and
            Langer T.
  TITLE     TRIAP1/PRELI complexes prevent apoptosis by mediating
            intramitochondrial transport of phosphatidic acid
  JOURNAL   Cell Metab 18 (2), 287-295 (2013)
   PUBMED   23931759
REFERENCE   2  (bases 1 to 1151)
  AUTHORS   McKeller MR, Herrera-Rodriguez S, Ma W, Ortiz-Quintero B, Rangel R,
            Cande C, Sims-Mourtada JC, Melnikova V, Kashi C, Phan LM, Chen Z,
            Huang P, Dunner K Jr, Kroemer G, Singh KK and Martinez-Valdez H.
  TITLE     Vital function of PRELI and essential requirement of its LEA motif
  JOURNAL   Cell Death Dis 1 (2), e21 (2010)
   PUBMED   21364629
REFERENCE   3  (bases 1 to 1151)
  AUTHORS   Tahvanainen J, Kallonen T, Lahteenmaki H, Heiskanen KM, Westermarck
            J, Rao KV and Lahesmaa R.
  TITLE     PRELI is a mitochondrial regulator of human primary T-helper cell
            apoptosis, STAT6, and Th2-cell differentiation
  JOURNAL   Blood 113 (6), 1268-1277 (2009)
   PUBMED   18945965
REFERENCE   4  (bases 1 to 1151)
  AUTHORS   Fox EJ, Stubbs SA, Kyaw Tun J, Leek JP, Markham AF and Wright SC.
  TITLE     PRELI (protein of relevant evolutionary and lymphoid interest) is
            located within an evolutionarily conserved gene cluster on
            chromosome 5q34-q35 and encodes a novel mitochondrial protein
  JOURNAL   Biochem J 378 (Pt 3), 817-825 (2004)
   PUBMED   14640972
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088284.1.
            
            On Jan 13, 2005 this sequence version replaced XM_214431.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088284.1, EV779019.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132276, SAMD00132293
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1151
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1151
                     /gene="Prelid1"
                     /gene_synonym="Preli; RGD1308082"
                     /note="PRELI domain containing 1"
                     /db_xref="GeneID:290995"
                     /db_xref="RGD:1308082"
     exon            1..233
                     /gene="Prelid1"
                     /gene_synonym="Preli; RGD1308082"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..795
                     /gene="Prelid1"
                     /gene_synonym="Preli; RGD1308082"
                     /note="protein of relevant evolutionary and lymphoid
                     interest"
                     /codon_start=1
                     /product="PRELI domain-containing protein 1,
                     mitochondrial"
                     /protein_id="NP_001009636.1"
                     /db_xref="GeneID:290995"
                     /db_xref="RGD:1308082"
                     /translation="MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREV
                     TPDQKLLSRRLLTKTNRMPRWAERLFPANVAHSVYILEDSIVDPQNQTMTTFTWNINH
                     ARLMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFGVSRAVQEFGLARFKSNVTKTMK
                     GFEYILAKLQGEAPSKTLVETAKEAKEKAKETALAATEKAKDLANKAATKQQQQQLV"
     exon            234..459
                     /gene="Prelid1"
                     /gene_synonym="Preli; RGD1308082"
                     /inference="alignment:Splign:2.1.0"
     exon            460..573
                     /gene="Prelid1"
                     /gene_synonym="Preli; RGD1308082"
                     /inference="alignment:Splign:2.1.0"
     exon            574..652
                     /gene="Prelid1"
                     /gene_synonym="Preli; RGD1308082"
                     /inference="alignment:Splign:2.1.0"
     exon            653..1090
                     /gene="Prelid1"
                     /gene_synonym="Preli; RGD1308082"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggcggta gggacctggg cgcggcgccg cggtgattga gctgcgagcc tggcgggcgt
       61 gcgccttgcc acgtgccctc cccacccccg ggctcttcac cctgatgctg cacgggtgct
      121 gagcccgccc gggtcgggac gatggtgaag tatttcctgg gccagagcgt gctccgaagt
      181 tcctgggacc aagtgttcgc tgccttctgg caacggtacc cgaatcccta tagcaaacat
      241 gtcttaaccg aagacatagt gcaccgggag gtgacccctg accagaagct tctgtcccgg
      301 agactcctga ccaagaccaa caggatgcca cgttgggcag agcgactgtt tcccgccaac
      361 gttgctcact cggtgtacat cctggaggac tcgattgtgg acccacagaa tcagaccatg
      421 accaccttca cttggaacat caaccacgcc cggctgatgg tggtggagga acgatgtgtt
      481 tactgtgtga actctgacaa tagcggctgg accgaaatcc gtcgggaggc ctgggtctcc
      541 tctagcttat ttggtgtctc cagagctgtc caggaatttg gtcttgcccg gttcaaaagc
      601 aatgtgacca agacaatgaa gggctttgaa tacatcctgg ccaagctaca aggtgaggcc
      661 ccttcaaaaa cacttgttga gacagccaag gaggccaaag agaaagcaaa ggagaccgca
      721 ctggcagcta cagagaaggc caaggacctg gccaacaagg ccgccaccaa gcagcagcag
      781 cagcagctcg tatagccctc ttcctctccc tcctcccccg tgtacttgat tattaaagat
      841 gaacctgcag ccctctctgc tgtctggggt ggtgggtcag agcgctgtcc tggtcagcat
      901 ctgcaccacg tccaggtcta tctgctgggc cggtcgaggg gtgcagtgac ttgcccaagg
      961 tcacagcagt gcaatagact gtacgctcca cgagggcagg actccccgtg tcctctgctg
     1021 ggtcccacgt cccctgaaca atatttagca cataacaggc actcaataaa cacatgattt
     1081 gactgcccca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1141 aaaaaaaaaa a
//
