LOCUS       NM_001191098            6869 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus PR/SET domain 13 (Prdm13), mRNA.
ACCESSION   NM_001191098 XM_001071683 XM_039110958
VERSION     NM_001191098.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6869)
  AUTHORS   Hanotel,J., Bessodes,N., Thelie,A., Hedderich,M., Parain,K., Van
            Driessche,B., Brandao Kde,O., Kricha,S., Jorgensen,M.C.,
            Grapin-Botton,A., Serup,P., Van Lint,C., Perron,M., Pieler,T.,
            Henningfeld,K.A. and Bellefroid,E.J.
  TITLE     The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj
            downstream target that suppresses glutamatergic and promotes
            GABAergic neuronal fate in the dorsal neural tube
  JOURNAL   Dev Biol 386 (2), 340-357 (2014)
   PUBMED   24370451
REFERENCE   2  (bases 1 to 6869)
  AUTHORS   Chang,J.C., Meredith,D.M., Mayer,P.R., Borromeo,M.D., Lai,H.C.,
            Ou,Y.H. and Johnson,J.E.
  TITLE     Prdm13 mediates the balance of inhibitory and excitatory neurons in
            somatosensory circuits
  JOURNAL   Dev Cell 25 (2), 182-195 (2013)
   PUBMED   23639443
REFERENCE   3  (bases 1 to 6869)
  AUTHORS   Kinameri,E., Inoue,T., Aruga,J., Imayoshi,I., Kageyama,R.,
            Shimogori,T. and Moore,A.W.
  TITLE     Prdm proto-oncogene transcription factor family expression and
            interaction with the Notch-Hes pathway in mouse neurogenesis
  JOURNAL   PLoS One 3 (12), e3859 (2008)
   PUBMED   19050759
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On or before May 18, 2023 this sequence version replaced
            XM_001071683.4, XM_039110958.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760389
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-272               JAXUCZ010000005.1  40029387-40029658   c
            273-404             JAXUCZ010000005.1  40027717-40027848   c
            405-525             JAXUCZ010000005.1  40027303-40027423   c
            526-6869            JAXUCZ010000005.1  40017607-40023950   c
FEATURES             Location/Qualifiers
     source          1..6869
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q21"
     gene            1..6869
                     /gene="Prdm13"
                     /note="PR/SET domain 13"
                     /db_xref="GeneID:689695"
                     /db_xref="RGD:1589883"
     exon            1..272
                     /gene="Prdm13"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..2249
                     /gene="Prdm13"
                     /note="PR domain containing 13; PR domain 13"
                     /codon_start=1
                     /product="PR domain zinc finger protein 13"
                     /protein_id="NP_001178027.1"
                     /db_xref="GeneID:689695"
                     /db_xref="RGD:1589883"
                     /translation="MHGTSRTSATSVNADCCIPAGLRLGPVPGTFKLGKYLSDRREPG
                     PKKKVRMVRGELVDESGGSPLEWIGLIRAARNPQEQTLEAIADLPGGQIFYRALRDVQ
                     PGEELTVWYSNSLAQWFDIPTTATPTHDEKGEERYICWYCWRTFRYPNSLKAHLRFHC
                     VLSGGGGRAFLPQEHAARPGASPVAEGLGLPPKPTAPDLTAPVQAAALRPQAQAAQLS
                     QACGTRESIKREASLAPLASSPPPGKWGTPKKGKEQPDRAHSHFLGIVGGSSAGSAGL
                     PFYPGVRSAFKPAGLARAAAQSDPYREEGGGKGPGLGLGRLLGGGRAAGRPGSGESPA
                     GHHHHHHHAHHHHHHHPKCLLAGEPPPAGLPCPGALRAFPLLAGHPEEASAFKHVERA
                     PPAAATAASLPAARYAALPAPGLPVERCALPPLDAGSLKAYPGGECSPLPAVMPAFTV
                     YSGDLLYGPPATYYPLKLHLGGLLKYPESISYLSGPAAAAAAAAAAAAAAAAIGPTEL
                     GSLASIDREIAMHTQQLSEMAAGKGRTRLDSGTLPPAVVAAAGPGGGGGGGGGGGAAG
                     KAKTGHLCLYCGKLYSRKYGLKIHMRTHTGYKPLKCKVCLRPFGDPSNLNKHIRLHAE
                     GNTPYRCEFCGKVLVRRRDLERHVKSRHPGQSLIAKAGDGSGAEPGYALEPGDPKSED
                     SDVDVCFTDDQSDPEAGGRGEHDS"
     exon            273..404
                     /gene="Prdm13"
                     /inference="alignment:Splign:2.1.0"
     exon            405..525
                     /gene="Prdm13"
                     /inference="alignment:Splign:2.1.0"
     exon            526..6869
                     /gene="Prdm13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actcagcgga cagaagacgc acgtcgggct gcggattcct cctcgcaggc ggctgctcct
       61 ggttctgtca cttgcgcccg gtggaggacc ccgtgagccc cagcgtctgc ctggcggcgg
      121 tggcaacaat gcacggaact tcccgcactt cggccaccag cgtgaacgct gactgctgca
      181 tcccggctgg cttgcgcctt gggccggtgc ctggcacctt caagctgggc aagtacctgt
      241 cagatcgcag ggaaccaggg ccgaagaaaa aggtgcgcat ggtgagaggg gagctggtgg
      301 acgagtcagg gggctctccc ctggagtgga tagggttaat ccgggcagcc aggaatcccc
      361 aggaacagac tctggaagct attgcagacc taccaggagg acagatcttc tatcgggcat
      421 tgcgagatgt ccagccaggc gaagagctaa ctgtgtggta ttctaactcc ttggctcagt
      481 ggtttgacat ccctacaact gcgactccga ctcatgatga gaaaggggag gagcgctaca
      541 tctgctggta ctgctggagg acctttcgat acccgaacag cctcaaggca cacctgcgtt
      601 tccactgcgt gctcagcggc ggcgggggcc gcgccttcct gcctcaggag cacgcggccc
      661 ggccgggcgc ttccccggtg gcagaaggcc tcggcctccc tccgaaaccc actgccccgg
      721 acttgacggc gcccgtccag gcagccgctc tgcggcctca agcccaggcc gctcagctct
      781 cccaggcgtg cgggacgagg gagagcatca agcgggaggc ttccctggcg cccctggcct
      841 cctccccgcc tcccggcaag tgggggacgc cgaagaaggg caaggagcag ccggaccgcg
      901 ctcacagtca cttcctgggg atcgtgggcg gctcctcagc cggcagcgca ggcctgccct
      961 tctaccctgg cgtgcgctcc gcattcaagc cggccggcct ggcccgggcc gctgcgcaga
     1021 gcgaccccta ccgggaagag ggcggcggca aggggcccgg gctggggcta ggccggctgc
     1081 tgggcggggg ccgggcggcc gggcgcccgg gcagtgggga gagcccggcg ggccaccacc
     1141 accatcacca ccacgctcac caccaccacc accaccaccc caagtgcctg ctggccgggg
     1201 agccgccgcc cgccggcctg ccgtgtcctg gggccctgcg ggccttcccc ctgctcgccg
     1261 gccacccgga agaggcgtcg gccttcaagc acgtggagcg ggctccgcct gccgcggcca
     1321 cggccgcctc gctgcccgcc gcgcgctacg ccgctctccc ggctcccggg ctccccgtgg
     1381 agcgctgcgc gctgccgccc ctcgacgccg gcagcctcaa ggcgtacccc gggggcgagt
     1441 gcagccctct tcccgccgtc atgccggcct tcacggtgta cagcggagac ctgctctacg
     1501 gcccgcccgc cacctattac cctctcaagc tgcacttggg cgggctgctc aaatacccgg
     1561 agtccatctc ctatttgagc ggccccgcgg cggcggcggc ggcagcagcg gcagcggcgg
     1621 cggcggcggc ggcgatcggc ccgactgagc tgggttccct ggccagtatc gaccgcgaga
     1681 tcgccatgca cacgcagcag ctgtccgaga tggcagccgg gaagggtcgt acccgcctgg
     1741 actccgggac gctgcctcca gccgtagtgg cggcggcagg ccccgggggt ggcggcggtg
     1801 gcggcggtgg cgggggcgcc gcaggcaagg ccaagacggg ccacttgtgc ctctactgtg
     1861 gcaagctgta ctcgcgcaag tacgggctca agatccacat gcggacgcac acgggctaca
     1921 agccgctcaa gtgcaaggtg tgcctgcggc ccttcggcga ccccagcaat ctcaacaagc
     1981 acatccgact ccatgcggag ggcaatacgc cctaccgctg cgagttctgc ggcaaggtgc
     2041 tggtgcgccg ccgagacttg gaacgtcacg tcaagtcccg ccacccaggc cagagcctga
     2101 tcgccaaggc gggcgacggc tcgggcgcgg agcccggcta tgctctggag cctggggatc
     2161 ccaagagcga ggacagtgat gtggatgtct gcttcactga cgaccagagc gaccctgagg
     2221 ctgggggccg tggcgagcac gactcctaat gcgccttcca gggaaggagc agggacttgg
     2281 acagagtaga gtgaagtggt gacaagaagg acttggttga tattgtccca gttctgggga
     2341 tggtgtcgga ttaggaacag ggagccgctc tccagttctg gagcagagtt taaggatggg
     2401 ttaaagaaac acagccaata aacaacccat acataggtct tgggtctcca tcaagcaggc
     2461 ccctagactc tggcatagtc tctcatcctg aaagcattct ggtgttgagg ttcaggatca
     2521 catcaatata agtatctcag tgccgtcaaa ggtgatgatt tttactgcca cgcaatttta
     2581 aaacgttctt ttctgtggag gaaatcgtgc cttttgaaaa gatgttctgc gtgaatttta
     2641 tgttaagtat ttcactgcat agcaagcaaa acagtagatg tgacacccgc acacctgttt
     2701 ccgttttata tctgttctcc tgtcagagag cactccttgc cacattgagt gtactgtggt
     2761 agtggatgta taaattggtc aagctgcaat tatttatgag agaatagtga taaatgtaaa
     2821 ataacgcatg aatataagag cacgcaatat ataaatttaa agatgcccta tttggtagca
     2881 tccaaatgtt tatgttgttt tataatgaat gatgtacagt gaatatagta ctttgccctt
     2941 gcttccgttt tgtgcaatcg ttaagaataa taaagatgca aatgagcatt ctattacttg
     3001 gctacttcag aggacccttt aaagacacag tttaatttga aaacaacctc tgaggagact
     3061 tgacaacaac ataagtcaca gaagatttat attatttgca gaattaatgt tagtcagagt
     3121 tgtatggaga acaggaaaga actcactgtt ttctaaaact attgttaacc atgctaagtg
     3181 tttttatgtt cacttcaaga tacacacaca cacacacaca cacacacaca ctcctttaca
     3241 tatgattggg gaactagaat cagtatttct tgtttgccat tttgacagat ttttaccatg
     3301 gagatacata agaggaaatt tgctcaagac atatcacaag tcatacacat tagtattcat
     3361 tcaacaaaca ctaaaggagg gcctatttta ttaaagatgc ttaagtcccc tccctcattt
     3421 gtacttccaa caactttgtg ctgtcagttt tggtcccatt taacagaaga aaaaaatgtc
     3481 acttgatcac agtgtatggg acaataacta gaataacaaa attgttagca gtgactgcat
     3541 tcactatgtt caagaagtgt ggctggatat acatcccagg aatgtttccc cctctccttt
     3601 tagaaggaag aattaggctt ttagttaaag gtagttacac tgagggcaga ggtgtgcagc
     3661 aattttaaga gttgatttaa agaatttgct agcttactag aagctctgga ctctgatgac
     3721 catgttcatc caatcatgtc ctttgagtcc tgaatcctga ctgctttgca aatccccact
     3781 gctatccctg attggaaaca ctgctgtggc cactaggtgg ttgccaggaa agccccccca
     3841 cccccacccc tttctctttt cttctttctc ttcctccttt ctttttcttt tcactctttc
     3901 ttttggcata tcacaaccaa gaacatatgg tttctattaa tggtgatctt caaaaagatt
     3961 tcttctctga gaagatgtga agatgtgtgc tggaacatat aggcttttag tgtaagctgg
     4021 ctagatattg ttttctagtg taagagaaag cataaagggg tgtggggaga cagacacaca
     4081 gacacacaga aagagagaca gagaaagaca aagacagaga aagacagaga cagagaggca
     4141 gagacaactc tagtggacct aatggtaaat gtacatttgt tgaagaacta cttgcatttt
     4201 gcatttcatt ttcagaacca ccctgttgtt tatttgaccc tgtgttacaa atgaagacac
     4261 tgtaacaaca gagggtctga cccagaatgt gacaattgta actatcagag acaaaactaa
     4321 aattcaggtg catctaatgt atttaaatta gccaatttaa atttcctctc cttgaagcag
     4381 gtagaggatg atcttgatac ccaagattta tcatttgctt gctaaactta catttccata
     4441 attcagtttt tcactaccag tttggagatc gtatttttgt actttgtagt cttgtctttt
     4501 gtaacaattg tcacttgaaa gcagattcat ccttgggtag aaggttgaaa agattttttc
     4561 cttctgaagt cagatcttgt cagtgctcag ggaaagtgag acaggctccc agatatgaaa
     4621 cacagggaat attatatgaa ctatatttcc tgcaccttat ttccctagtt cagttgtaat
     4681 tgtaattctt gtttagtggg aaaatagaca ataaacaacc aagataagaa ttgtttggtt
     4741 aaatgaaata catggagaat tgaaatgata tcataaaaca aaaccacagc cacctgtttc
     4801 ttcctattag actagattgc aacattaaaa atagaacaat taaacataga tttacaaagc
     4861 tcttaattgc agcttgtttg taattctcta taggttgact aagacaaccc cccatttgtt
     4921 catgctcgaa ttctaactac atagataatt accgtcattg tttatctcta cgtcatagtc
     4981 aaatcagtaa aacacagtca gctaaatgag cccccccccc cactctgtcc ccctgagaca
     5041 ggattttgct atgtacctta gactggtctt gaactcgggg aaatcctgcc tcagtctccc
     5101 tttcttttta ctcccattta ctcaacagct tttaccttgg agatggtagg tcattcttag
     5161 agcaaaggca ctgaatattt taaagatttt aacagaatat caatcttaaa agaaaaggag
     5221 ggcaggtcat gccttttaga agcgaaagcc tccagattgc ttggttttag ttaatttgga
     5281 tattgaaaag ttttgctaat ttaagtacat cagatgcacc tggattttag ttttgtctct
     5341 gagttacaat ggtcacattc ggggtcagac tgtctattgc tacagtgtct tcatttgtaa
     5401 cacagggtca aataagcaac agggtggttt tgaacaataa gaggtgatac tagtaagtgg
     5461 ctaagcattc tgcagggtgc actgaaagcc ctcactccta ctctagtaag aatctacttt
     5521 catttaaaag accccactgt aaggagaagg gctgatgcag ggttttatac gcattggcag
     5581 cttgcacagg acaccagctt tgttcttcca gcccctggtg aagtcacatc aatttcagta
     5641 aatagaggct ttcgacactt ggagaaactt cagacctctt gctcggtttc cattgtaagt
     5701 cccggagcca gttccagaga ctcatggcat ggagagaatg ctgttttcgt ttccagttac
     5761 taagttttga aaagcttgct ggactctgag ggttgagctt aaacagaagc acaggggaga
     5821 ggcgaataag tgcacacctc ctttctttag actcctctta gtcttagaca agacttcaag
     5881 aagtgcggaa ggtctggcag tgctggggaa agtggcgtta ctctaagctc agtacaaatg
     5941 aatggttagc gctgtggccg gccggaactg agccaaacag agccggtcat tgtcgttatt
     6001 cctagagccc ccattggctc atcctttgca tccaggctgc tattggtgat agactcaaag
     6061 tgtgctggag attaggttgc agcacctggg tcttgggtgg cgtcagactt ggggcttcgt
     6121 gtgctagcgg ctgtcaacct gagtccttta gcgacccagc ttcgcttaag tttcagagag
     6181 gagtttccga attgggtaat ggaatgggaa tttcaccact tttgggagca cagccctgga
     6241 gccccaggag aaaatgtgct tgaaaagccg cagagactcg cagctggacg aggggtctca
     6301 gcccagcgtg ttcctggtct gtgtcctgcc cggctgcagc aaggatctgc gcaccagagc
     6361 cctgcgccct tgccatctgc cgcctcccca aagagaagaa ggcagaggca cccgcactgt
     6421 cgaggttata tgtgaccctt gaccacccag gtgtgagcag cacagggagg attcaaaaga
     6481 ctgcgcagcc caagcctgaa ggagcgctcg gctagctcac taggtgacct tcctataaaa
     6541 gatgaaaaga gagcttctgc catctgcaac tatagcttaa ttcaagttag agaaaacgtg
     6601 tgacagactt gttaatgcct tcgacttgga aaccaacggt ccttcagaag ggaccaagac
     6661 tgggtggata gcccctttaa aaacttcatt ttcagtacaa tatgttattt aaattcaagc
     6721 attttacgta aatagataaa aacttaaaag acaagtttat tgaaaaatgt aaaagtcata
     6781 tcatcaaagg taaaattggt tatttgagtt aagtaaaggc cagcgtttca cctactgtga
     6841 ataaatttaa atgttcgtct aaaatgaaa
//
