LOCUS       NM_001271530            3755 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus PR/SET domain 11 (Prdm11), mRNA.
ACCESSION   NM_001271530 XM_001074223
VERSION     NM_001271530.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3755)
  AUTHORS   Fog,C.K., Asmar,F., Come,C., Jensen,K.T., Johansen,J.V.,
            Kheir,T.B., Jacobsen,L., Friis,C., Louw,A., Rosgaard,L., Obro,N.F.,
            Marquart,H.V., Anthonsen,K., Braat,A.K., van Lohuizen,M.,
            Ralfkiaer,E., Gronbaek,K. and Lund,A.H.
  TITLE     Loss of PRDM11 promotes MYC-driven lymphomagenesis
  JOURNAL   Blood 125 (8), 1272-1281 (2015)
   PUBMED   25499759
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001271530.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-75                JAXUCZ010000003.1  99460350-99460424   c
            76-200              JAXUCZ010000003.1  99428614-99428738   c
            201-304             JAXUCZ010000003.1  99428172-99428275   c
            305-567             JAXUCZ010000003.1  99427475-99427737   c
            568-635             JAXUCZ010000003.1  99409063-99409130   c
            636-823             JAXUCZ010000003.1  99396097-99396284   c
            824-1435            JAXUCZ010000003.1  99390878-99391489   c
            1436-3755           JAXUCZ010000003.1  99387518-99389837   c
FEATURES             Location/Qualifiers
     source          1..3755
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q31"
     gene            1..3755
                     /gene="Prdm11"
                     /gene_synonym="RGD1305673"
                     /note="PR/SET domain 11"
                     /db_xref="GeneID:690358"
                     /db_xref="RGD:1597330"
     exon            1..75
                     /gene="Prdm11"
                     /gene_synonym="RGD1305673"
                     /inference="alignment:Splign:2.1.0"
     exon            76..200
                     /gene="Prdm11"
                     /gene_synonym="RGD1305673"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..3600
                     /gene="Prdm11"
                     /gene_synonym="RGD1305673"
                     /note="PR domain containing 11; PR domain 11"
                     /codon_start=1
                     /product="PR domain-containing protein 11"
                     /protein_id="NP_001258459.1"
                     /db_xref="GeneID:690358"
                     /db_xref="RGD:1597330"
                     /translation="MTENMKECLAHTKAAVGDMVTVVKTEVCSPLRDQEYGQPCSRRL
                     EPSSMEVEPKKLKGKRDLIVTKSFQQVDFWFCESCQEYFVDECPTHGPPVFVSDTPVP
                     VGIPDRAALTIPQGMEVVKEVGGESDVRCINEVVPKGHIFGPYEGQISTQDKSAGFFS
                     WLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIRPG
                     ERLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKAEQALDNPEDLRGPSHFPVL
                     KQGRSPYKRSFDEGDLHPQAKKKKIDLIFKDVLEASLESANAEGRQLALSTSLVIRKV
                     PKYQDDDYGRAALTQGICRTPGEGDWKVPQKVAKELGPLEDEEEEHTSFKADSPAEAS
                     LASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKVPEPPILPQQVLELPEFSDP
                     AASESMVSCPAIMEDDDQEVDSADESVSNDVMTATDEPSKLSSATGRRIRRFKQEWLK
                     KFWFLRYSPTLNEMWCHVCRQYTVQSSRTSAFIIGSKQFKIHTIKLHSQSNLHKKCLQ
                     LYKLRMHPEKTEEMCRNMTLLFNTAYHLALEGRPYLDFRPLAELLRKCELKVVDQYMN
                     EGDCQILIHHIARALREDLVERIRQSPCLSIILDGQSDDLLADTVAVYVQYTSSDGPP
                     ATEFLSLQELGFSSTESYLQALDRAFAALGIRLQDEKPTVGLGVDGANITASLRASMF
                     MTIRKTLPWLLCLPFMVHRPHLEILDAISGKELPCLEELENNLKQLLSFYRYSPRLMC
                     ELRSTASTLCEETEFLGDIRAVRWIIGEQNVLNALIKDYLEVVAHLKDVSSQTQRADA
                     SAIALALLQFLMDYQSIKLIYFLLDVIAVLSRLAYIFQGEYLLVSQVDDKIEEAIQEI
                     SRLADSPGEYLQEFEENFRESFNGIAVKNLRVAEAKFQSIREKICQKTQVILAQRFDS
                     RSRVFVKACQVFDLAAWPRNNEELLSFGKEDMVQIFDHLEAIPAFSRDVCREGMDPRG
                     SLLMEWRDLKADYYTKNGFKDLISHICKYKQRFPLLNKIIQVLKVLPTSTACCEKGRS
                     ALQRVRKNHRSRLTLEQLSDLLTIAVNGPPIASFDAKRALDSWFEEKSGNSYTLSAEV
                     LSRMSALEQKPMLQAVDHGSEFYPDM"
     exon            201..304
                     /gene="Prdm11"
                     /gene_synonym="RGD1305673"
                     /inference="alignment:Splign:2.1.0"
     exon            305..567
                     /gene="Prdm11"
                     /gene_synonym="RGD1305673"
                     /inference="alignment:Splign:2.1.0"
     exon            568..635
                     /gene="Prdm11"
                     /gene_synonym="RGD1305673"
                     /inference="alignment:Splign:2.1.0"
     exon            636..823
                     /gene="Prdm11"
                     /gene_synonym="RGD1305673"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1435
                     /gene="Prdm11"
                     /gene_synonym="RGD1305673"
                     /inference="alignment:Splign:2.1.0"
     exon            1436..3755
                     /gene="Prdm11"
                     /gene_synonym="RGD1305673"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgcccc gtcccgccgc gtcccgccgc cccggccccg gcccggcccg ccgccccgcg
       61 tgggaacccg cgaaggacag aatgactgag aacatgaagg agtgcttggc ccacaccaag
      121 gcggctgtag gggacatggt gacagtagtg aagacagagg tctgctcacc actccgggac
      181 caggagtatg gccagccctg ctctcggaga ctggagccat cttccatgga agttgaacct
      241 aagaaactaa agggaaaacg tgacctcatc gtgaccaaaa gcttccagca agtggacttc
      301 tggttctgcg agtcctgcca agagtacttt gtggatgaat gtccgaccca tggtcccccc
      361 gtgtttgtgt ctgacacacc agtgcctgtg ggcatcccag atcgggcggc cctcaccatt
      421 ccacagggca tggaggtggt aaaggaagtt ggtggagaga gcgatgtgcg gtgtataaat
      481 gaagtcgtcc ccaagggtca catctttggc ccctatgagg ggcagatctc tacccaggac
      541 aagtcagctg gcttcttctc atggctgatt gtggacaaga acaaccgcta caagtccata
      601 gatgggtcag atgagaccaa ggccaactgg atgaggtacg tggtcatttc ccgggaggag
      661 agggagcaga acctcctggc cttccagcac agcgagcgca tctacttccg ggcatgccga
      721 gacatccggc caggagagcg gctgcgggtc tggtacagcg aggactacat gaagcgtctg
      781 cacagcatgt cccaggaaac catccaccgc aacctggccc ggggagagaa gagattgcag
      841 agagagaagg ctgagcaagc cctggataac ccagaagacc taaggggtcc ctcccatttc
      901 cctgtgttga agcagggcag aagtccttac aagcgcagct ttgatgaggg ggacctccac
      961 cctcaggcca agaagaagaa aatagacctc atcttcaagg acgtcctgga agcctcactg
     1021 gagtctgcta acgcggaagg ccgccagctg gccctgagca cctccctggt catccggaaa
     1081 gtccccaagt accaggacga tgactatggt agagctgccc tgacacaagg catctgcagg
     1141 accccagggg aaggggactg gaaggtccct caaaaggtgg ccaaggagct aggcccactg
     1201 gaagatgaag aggaggagca tacgtcgttc aaggccgaca gccccgctga ggcctctctg
     1261 gcatctgacc cccacgagct gcccaccacc tccttttgcc ctaactgcat ccgactgaaa
     1321 aagaaagtgc gggaattgca ggcggagcta gatatgctta agtctggaaa ggtgcctgag
     1381 cctcccattc tgccacagca ggtactggag ctcccagagt tctcagatcc tgcagcttca
     1441 gagagtatgg tctcctgccc agccatcatg gaggacgacg accaggaagt ggattctgca
     1501 gacgaatctg tctccaatga cgtgatgacg gcaaccgacg aaccctccaa gttgtcctct
     1561 gccacgggac gccgcatccg gcgcttcaag caggagtggc tgaagaagtt ctggttccta
     1621 aggtactccc cgaccctcaa cgagatgtgg tgccatgtgt gccgccagta cacggtgcag
     1681 tcctcacgca cgtccgcctt catcatcggc tccaagcagt tcaagatcca caccatcaaa
     1741 ctgcacagtc agagtaacct gcacaagaag tgcctgcagc tgtacaagct gcgcatgcac
     1801 ccggagaaga cagaggagat gtgccgcaac atgaccctgc tcttcaacac tgcctaccac
     1861 ctggcactgg agggaaggcc ctacctcgac ttccggccac tggcagagct gctgcgtaag
     1921 tgcgagctca aggtggtgga ccagtatatg aatgaggggg actgccagat cctcatccac
     1981 cacatcgccc gggcactgcg agaggacctg gtggagcgca tccgtcagtc accctgcctc
     2041 agcatcatcc tggatgggca gagtgacgac ctcctggctg acacggtggc cgtctatgtg
     2101 cagtatacca gcagcgatgg gcccccggcc acagaattcc tatccttgca ggagctaggc
     2161 ttctccagca cagaaagcta tctccaggct cttgaccggg cctttgctgc tctgggcatc
     2221 cgcttacagg atgagaagcc aactgtgggc ctgggagtcg atggggccaa catcaccgcc
     2281 agcttgcgtg ccagcatgtt catgaccatc cgcaagacgc tgccatggct gctgtgcttg
     2341 cccttcatgg tgcaccggcc acacctggag atcctggatg ccatcagtgg gaaggaactg
     2401 ccctgtctag aggagctgga gaacaacctg aagcagctcc tcagcttcta ccgctactca
     2461 ccacgcctca tgtgtgagct gcgctccacg gcctctaccc tgtgcgagga gactgaattc
     2521 ctgggagaca tccgtgccgt gaggtggatc atcggtgagc agaatgtctt gaatgccctt
     2581 atcaaggatt acctggaagt ggtggcccac ctgaaggatg tcagcagcca gacacagcgg
     2641 gcagacgctt ccgccatagc cctggccctg ttgcagttcc tcatggacta ccagtccatc
     2701 aagctcatct acttcctgct ggatgtgatt gccgtgctgt cacgcctggc ctacatcttc
     2761 cagggagagt acctactggt gtcacaggtg gatgacaaga tcgaggaggc aatccaggag
     2821 atcagtcggc ttgcagactc cccgggagag tacctgcagg aatttgagga gaatttccga
     2881 gagagcttca atgggatcgc tgtgaagaac ctcagggtgg cagaggccaa gtttcagtct
     2941 atcagggaga agatctgcca gaagacacag gtcattctgg ctcagaggtt cgactcccga
     3001 agccgggtct ttgtgaaggc ctgccaagtg ttcgacttag ccgcctggcc caggaacaat
     3061 gaggagcttc tgagcttcgg caaggaagat atggttcaga tctttgacca cttggaagcc
     3121 attcctgcct tctcccggga tgtgtgccgt gaagggatgg acccccgggg gagcctgctg
     3181 atggagtgga gagacctcaa ggctgattac tacaccaaaa atggcttcaa agacctcata
     3241 agccacatct gcaagtacaa gcagaggttt ccgctcttga acaagatcat tcaggtcctt
     3301 aaagttctcc ccacctccac tgcctgctgt gagaaaggcc gaagtgccct ccagcgggtc
     3361 cgcaaaaacc accgctcacg cctgaccctg gagcagctca gtgacctgtt gacgattgct
     3421 gtgaacggac cacccatcgc cagctttgat gccaagcgag ccctggacag ctggtttgag
     3481 gagaagtctg gcaacagcta cacactttca gccgaggtcc tcagtaggat gtctgccttg
     3541 gagcagaagc ccatgctgca ggctgtggac catggctctg aattctaccc agacatgtag
     3601 gggggctgcg ctccagaggc cacaaagacg gtgaatattt ttttaatcta tactcataag
     3661 ctttgatata ttatataaat atatattata ttatattata tatatataaa cccacactga
     3721 aattttttta aaaactaagt taattatgtc cacca
//
