LOCUS       NM_001107529            2928 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus protein regulator of cytokinesis 1 (Prc1), mRNA.
ACCESSION   NM_001107529 XM_001061201 XM_218820
VERSION     NM_001107529.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2928)
  AUTHORS   Subramanian R, Ti SC, Tan L, Darst SA and Kapoor TM.
  TITLE     Marking and measuring single microtubules by PRC1 and kinesin-4
  JOURNAL   Cell 154 (2), 377-390 (2013)
   PUBMED   23870126
  REMARK    Erratum:[Cell. 2013 Nov 21;155(5):1188]
REFERENCE   2  (bases 1 to 2928)
  AUTHORS   Subramanian R, Wilson-Kubalek EM, Arthur CP, Bick MJ, Campbell EA,
            Darst SA, Milligan RA and Kapoor TM.
  TITLE     Insights into antiparallel microtubule crosslinking by PRC1, a
            conserved nonmotor microtubule binding protein
  JOURNAL   Cell 142 (3), 433-443 (2010)
   PUBMED   20691902
REFERENCE   3  (bases 1 to 2928)
  AUTHORS   Kanehira M, Katagiri T, Shimo A, Takata R, Shuin T, Miki T, Fujioka
            T and Nakamura Y.
  TITLE     Oncogenic role of MPHOSPH1, a cancer-testis antigen specific to
            human bladder cancer
  JOURNAL   Cancer Res 67 (7), 3276-3285 (2007)
   PUBMED   17409436
REFERENCE   4  (bases 1 to 2928)
  AUTHORS   Neef R, Gruneberg U, Kopajtich R, Li X, Nigg EA, Sillje H and Barr
            FA.
  TITLE     Choice of Plk1 docking partners during mitosis and cytokinesis is
            controlled by the activation state of Cdk1
  JOURNAL   Nat Cell Biol 9 (4), 436-444 (2007)
   PUBMED   17351640
REFERENCE   5  (bases 1 to 2928)
  AUTHORS   Zhu C, Lau E, Schwarzenbacher R, Bossy-Wetzel E and Jiang W.
  TITLE     Spatiotemporal control of spindle midzone formation by PRC1 in
            human cells
  JOURNAL   Proc Natl Acad Sci U S A 103 (16), 6196-6201 (2006)
   PUBMED   16603632
REFERENCE   6  (bases 1 to 2928)
  AUTHORS   Gruneberg U, Neef R, Li X, Chan EH, Chalamalasetty RB, Nigg EA and
            Barr FA.
  TITLE     KIF14 and citron kinase act together to promote efficient
            cytokinesis
  JOURNAL   J Cell Biol 172 (3), 363-372 (2006)
   PUBMED   16431929
REFERENCE   7  (bases 1 to 2928)
  AUTHORS   Yagil C, Hubner N, Monti J, Schulz H, Sapojnikov M, Luft FC, Ganten
            D and Yagil Y.
  TITLE     Identification of hypertension-related genes through an integrated
            genomic-transcriptomic approach
  JOURNAL   Circ Res 96 (6), 617-625 (2005)
   PUBMED   15731461
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473980.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001061201.1, XM_218820.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2928
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..2928
                     /gene="Prc1"
                     /note="protein regulator of cytokinesis 1"
                     /db_xref="GeneID:308761"
                     /db_xref="RGD:1311754"
     exon            1..129
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..1939
                     /gene="Prc1"
                     /codon_start=1
                     /product="protein regulator of cytokinesis 1"
                     /protein_id="NP_001100999.1"
                     /db_xref="GeneID:308761"
                     /db_xref="RGD:1311754"
                     /translation="MRRSEVLADESIVCLQKALTHLREIWGLIGIPEEQRLQRTEVVK
                     KHIKDLLDKMIAEEENLRERLLKSISICRKELSTLCSELQVKPFEEDKEITVLQLEKD
                     LRTQVELMRKQKKERKQELKLLQEQDQELREILCMPPCDVDSTSVPTLEELNLFRQRV
                     ATLRETKESRHEQFVNIKRQIILCMEELEHTPDTSFERDVVCEDESAFCLSLENIATL
                     QKLLKQLEVKKSQNEAECEGLRAQIRELWDRLQIPEEEREPVAAIMTGSKTKIRNALK
                     LEVDRLEELKMQNIKQVIETIRVELAQFWDQCFYSQEQRQAFAPYYSEDYTENLLHLH
                     DVEVIRLRNYYEAHKELFEGVQKWEESWKLFLEFERKASDPSRFTNRGGNLLKEEKER
                     AKLQKTLPKLEEELKARIEHWEQENSTAFVVNGQKFMEYVTEQWELHRLEKERAKQER
                     QLKNKRQTETEMLYGSAPRTPSKRPGQTPNKCGKVRKMNTTTMSTATPNSSIRPVFGG
                     SVYRSPMSRLPPSGSKSVVTSLCSGKKTPRAARLRANKENLDLNGSILSGGYSGSTPL
                     QRNCSIKSVASTYSEFSRELSKASRSDATSRILNSTNIQS"
     exon            130..262
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            263..385
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            386..619
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            620..790
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            791..940
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1088
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1225
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1321
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..1468
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1579
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1580..1690
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..1867
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1868..2928
                     /gene="Prc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caacggctcg agagtggaga ccgactgaaa gttgaaggct gccgtggctg cttaccttcc
       61 tccgtcccgc gcgtgggaag tggagggtct cgattctgga cggctcggag catccgccat
      121 gaggagaagt gaggtgctag cagacgagtc catcgtatgc ctccagaaag ctctaactca
      181 ccttcgggaa atatgggggt taattgggat tcccgaggag cagagactac aaagaaccga
      241 ggttgtaaag aagcatataa aggatcttct ggataaaatg attgctgagg aggagaacct
      301 gcgggaaagg cttctcaaga gcatatccat ctgtcggaag gagctgagca ccctgtgcag
      361 cgagctacaa gtcaagccat ttgaggaaga taaagaaata actgtcttgc aattagaaaa
      421 agatttgcgc actcaagtag aattgatgag aaaacagaaa aaggagagaa agcaggaact
      481 taagctactt caagaacaag atcaagagct ccgtgaaatt ctgtgtatgc ctccctgtga
      541 tgtagacagc acctctgtcc ccaccttaga agagctgaat ctattccgac aacgtgtggc
      601 aactttgagg gaaacaaagg aatcgaggca tgaacaattt gtcaacatta agagacaaat
      661 catattgtgt atggaagaat tagagcacac tccggataca agctttgaaa gagacgtagt
      721 gtgtgaggat gagagtgcct tttgtttatc actggagaat attgcaacat tacagaagct
      781 gctaaagcag ctggaagtga aaaagtcaca aaatgaagca gaatgtgagg ggctccgtgc
      841 tcaaatccga gagctctggg ataggctaca gatacctgaa gaggagagag aacctgtggc
      901 tgcaattatg actgggtcaa aaaccaaaat caggaatgcg ttgaaattag aagtggatcg
      961 gttagaagaa ctgaaaatgc aaaacataaa gcaagtgatt gagacaattc gagtggagct
     1021 ggctcagttc tgggaccagt gcttttatag ccaggaacag aggcaggctt ttgcccctta
     1081 ctattctgag gactacacag aaaacctgct ccatcttcat gatgttgagg ttatacggtt
     1141 aagaaactat tatgaagctc acaaggaact gtttgaagga gtccagaaat gggaagagag
     1201 ctggaaactt ttcctagagt ttgagagaaa agcttcagat ccaagtcggt ttacaaaccg
     1261 agggggaaat cttttaaaag aagaaaagga acgagcaaag ctccagaaaa cactccctaa
     1321 gctggaagag gagttgaagg cacggattga acactgggaa caagagaact caacagcatt
     1381 tgtggtgaac gggcagaaat tcatggagta tgttacagag cagtgggagt tacatcggtt
     1441 ggagaaagag cgagccaaac aggagaggca actaaagaac aagagacaga cagagacaga
     1501 gatgctgtac ggcagtgctc cccggacacc tagcaaaaga ccaggacaga ctcccaacaa
     1561 gtgtggcaaa gtacgcaaga tgaacactac caccatgtct actgctacac ccaatagtag
     1621 cattcggcct gtctttggtg gatcagtgta ccgttcacct atgtctcgac tacccccttc
     1681 tggcagcaag tcagtagtca cttctctatg ttctggaaag aaaacaccta gagctgcccg
     1741 gcttagggcc aacaaggaga acttggacct caatggcagc atcctgagcg gtgggtactc
     1801 tggctcgacg cccctccagc gcaactgcag cattaagtct gttgccagca cctattctga
     1861 gttttcgcga gaactgtcaa aggcttccag atctgatgct acttctcgaa tcctcaattc
     1921 caccaacatc cagtcctgag aatccctgtc cagttagcca gctgtggttt cctgtgccta
     1981 gactggactg acgaacccaa ggggcgactt tccaacagtt taatgtttga aacaactacc
     2041 ttgggcaggt tctgttaact gcgccttcct tagacaggaa ggagcacaag agaagaaagc
     2101 cttcacgggc acagagtcaa gagaccttaa gtttttgagt caagagatct taaaagctag
     2161 ttacgatagt tatacaagct ttttaacatc tggtagctat ttttttctct accccataat
     2221 tctacgtaaa gaatgatcaa gggtttgtca taatactata ttggaaaatg aaaaaaatga
     2281 ttatgcccag ctttggggta cagggtgaga catgaagtaa ttctgacttg tagacttgga
     2341 attaacatct aaaaatatat tttttgttct tggacatttg attaatgctg tagctgtagt
     2401 aactttgatc ttacccagag gcctgtaccc agcagtgtac tattctggtt ccttgtgtct
     2461 cagcattcga gatggcctga gctgccgcca aaagagcagc agcgacagtt gtttctgtag
     2521 tgcaatcttg gaggggtgtg tgtgtgaaca cacattctct gacctcttca gtctttctcc
     2581 agtctcccaa ccctgtgctc accgggccta gtctgttccc tgtagttgac aaccaaatag
     2641 agaagctatc tgggtgggtt gggccatttc tgtcatggac tccacaactt tgcacatctc
     2701 catgttatct gtgtgatcac gtccacactg aggctctttc ttgcctaccc agttcatcac
     2761 tactctcccc aaagcactat tatttattct gtctgtgcca gttctgccaa cacattaaat
     2821 gattctttaa aacctggtct gtgtcagtat gctgtctact cacacacata tatatgttgt
     2881 ttttaaacat attaaaataa aatgtatata gttaatcttt caaatact
//
