LOCUS       NM_001107141            4234 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus protein phosphatase targeting COQ7 (Pptc7), mRNA.
ACCESSION   NM_001107141 XM_001079551 XM_222189
VERSION     NM_001107141.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4234)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 4234)
  AUTHORS   Gonzalez-Mariscal,I., Martin-Montalvo,A., Vazquez-Fonseca,L.,
            Pomares-Viciana,T., Sanchez-Cuesta,A., Fernandez-Ayala,D.J.,
            Navas,P. and Santos-Ocana,C.
  TITLE     The mitochondrial phosphatase PPTC7 orchestrates mitochondrial
            metabolism regulating coenzyme Q10 biosynthesis
  JOURNAL   Biochim Biophys Acta Bioenerg 1859 (11), 1235-1248 (2018)
   PUBMED   30267671
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473973.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001079551.1, XM_222189.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760393,
                              SAMEA5760494 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4234
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..4234
                     /gene="Pptc7"
                     /gene_synonym="RGD1310383"
                     /note="protein phosphatase targeting COQ7"
                     /db_xref="GeneID:304488"
                     /db_xref="RGD:1310383"
     exon            1..517
                     /gene="Pptc7"
                     /gene_synonym="RGD1310383"
                     /inference="alignment:Splign:2.1.0"
     CDS             286..1209
                     /gene="Pptc7"
                     /gene_synonym="RGD1310383"
                     /EC_number="3.1.3.16"
                     /note="T-cell activation protein phosphatase 2C; PTC7
                     protein phosphatase homolog"
                     /codon_start=1
                     /product="protein phosphatase PTC7 homolog"
                     /protein_id="NP_001100611.1"
                     /db_xref="GeneID:304488"
                     /db_xref="RGD:1310383"
                     /translation="MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGSGDYGLVTAGC
                     GFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMR
                     TCERLVKEGRFVPSNPVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLG
                     DSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLG
                     DIILTATDGLFDNMPDYMILQELKKLKNSNYESIQRTARSIAEQAHELAYDPNYMSPF
                     AQFACDNGLNVRGGKPDDITVLLSIVAEYTD"
     exon            518..697
                     /gene="Pptc7"
                     /gene_synonym="RGD1310383"
                     /inference="alignment:Splign:2.1.0"
     exon            698..896
                     /gene="Pptc7"
                     /gene_synonym="RGD1310383"
                     /inference="alignment:Splign:2.1.0"
     exon            897..1020
                     /gene="Pptc7"
                     /gene_synonym="RGD1310383"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1150
                     /gene="Pptc7"
                     /gene_synonym="RGD1310383"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..4234
                     /gene="Pptc7"
                     /gene_synonym="RGD1310383"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acacgctagt ggagcggaag atggcggcgg cggctgcggc tgcagccggg accccagttt
       61 ggttgaggcg gaggagccgc cggctctgac ctcgctctgg ctccagtgcg tgcggtagag
      121 cgtgtgcgag gccccgtgcg gcgggcaggg gcggcagtgg ccagtgcgcg ccgccctgag
      181 gaacgcccgg gcggcgctgc tgcggctgag gagagagccg gctccgggcc tcggcgtcct
      241 cctgcgccct gggccccgcg cctcctcggg ggggcggcgg cggcgatgtt ctcggtcttg
      301 tcgtacgggc ggctggtggc ccgcgctgtg ctcggcggcc tgtcgcagac cgaccccagg
      361 gcgggcggcg gcggaggcgg cggcagcggc gactacgggc tggtgacggc gggctgcggc
      421 ttcggcaagg acttccgtaa gggcctgctc aagaagggcg cgtgctacgg ggacgacgcg
      481 tgtttcgtgg cccgccaccg ctcggccgac gtgctgggag ttgcggatgg cgttggaggg
      541 tggagagact atggagtgga cccgtctcag ttctcaggga ctttaatgcg aacatgtgag
      601 cggttagtaa aagaaggacg ctttgtcccc agcaatcctg ttgggattct caccacgagc
      661 tactgtgagt tgctgcaaaa caaagtaccc ttgctgggta gcagcacagc ctgcatcgtg
      721 gtgctggaca gaagtagcca ccgtctgcac acagcgaacc tgggtgactc gggcttcctg
      781 gtggtccggg gcggcgaggt cgtgcaccgc tctgatgagc agcagcatta cttcaacact
      841 ccattccagc tctccattgc tcccccggaa gctgagggag tcgtcctgag cgacagcccc
      901 gatgctgctg acagcacatc tttcgatgtt cagttaggag acatcatcct gacagcgaca
      961 gatgggctct ttgacaacat gcctgattat atgatccttc aggagctgaa aaaactgaag
     1021 aattcaaatt atgagagcat acagcggact gcaaggagca tcgctgagca agcgcacgag
     1081 ctggcctatg acccaaatta catgtcacct ttcgcacagt tcgcatgtga caacggatta
     1141 aatgtgagag gtggaaaacc agatgacatc accgtgctcc tctcaatagt ggctgagtac
     1201 acggactgac tggccacact ggtgactcct gcctttccct tgtccccaac gtttccctgc
     1261 cacgtgtgct gatcctgctg gcaggaccac atttctttgc cactgatctg tggccactga
     1321 tggatgctct ggcccacgtt tgagacccat ggagatcctt gctgagaacc actactgtca
     1381 tgcgctagcc cggacctgct ggcgaccctc tgagagaagc gaggccacct ctcccttctc
     1441 ctggaggttt tcaaagcctt ttacttttca aaagcagttg aagttttgaa aataagtaat
     1501 gttggtaaag tgaactcaaa atttcagtgt gttaaaggga tgttaacagt tgacaaatag
     1561 tgaatagtga cagctctaca gagcacacat ggtcgtccca ggagaaccag ccctgtgtcc
     1621 cacaggtgca gtctctgcta ggactggtat ggtttgtgtc ttctgtataa actcctgatt
     1681 tcaggagctc acagccctgc cctaaccctg tgctgggcac tggcatctca accccagcgg
     1741 tggatggctt gggttacaaa ttggaaggaa atttttgttc tgtggatgca gatgttttgt
     1801 gctttttaaa agatgcttaa ttgtgcccct gtgactgcag ctgtggcagt ctgttgattt
     1861 gtccaggtca caggctagag gcaggagagg gacagggaaa tctagtaaag gaaatactac
     1921 gcaaaatttc aaactcctca aagcctggga atcagtgctg tagctgaggt cgtccgcgct
     1981 gcctgtaagg atgccccggg ctttcctaga gtagagaacg cagctgcagc tcggaatggg
     2041 gctggctgtg gacagccttg ctcctccccc tcaggagccg cccaccctcc catgccccac
     2101 ctgcgttgtg tcctcaaggt gatgatggcc tggtggcgcg gtggctgcat ctcccagagc
     2161 ccacaggaaa gccagtggta cctgacattc acagtgacat cacagctgag tgtggggccc
     2221 tgagtccggc ttactgttta cagtccccaa tagccatcgc agtaggtgac gctccttccc
     2281 agaatccccc agtacctgcg agcgcagact tgtttttaag gtttatgtac aactgactgc
     2341 tgtaaagata tatatatatt tttgggtccg ttcttttcct tcattaacgt ggtggtagaa
     2401 aaaccatata tacttagaaa cccttaagtt aaagccgtgt tttctgtgcg agtcagatga
     2461 tgctggcgcg aagacggtgt gagcagctgc acagcccgtc ctctgcagga gacactggct
     2521 ccccgggtat tgcattgaac ttgtgtgtga ggttacctca acttgttttt aaaggttttg
     2581 tctgtgtgtc tgtatatttg agtagctgtg tcttgtttta tttaaattgt ttaccatgta
     2641 ccatgtacat gtcagtgctc tcagtgcatc atgcttgtaa caggcatttc atttataaga
     2701 atgagttact catttgtaag ctgttcagta atttatctac tattcctaaa ttggcataat
     2761 gttagattcc tgtattgaat cacctttaat tacacgtcag aatgccttaa ctaccctaac
     2821 ctgacaacac tgagctctct ggtgaggaga tacagcggcc gggatgcagg gagactggac
     2881 taaggagacg cgccgcgttc tgttgatcct ggggcacgag gggcacgtgg tgggtattta
     2941 ttttgcacaa actctttaca gtgtctgtgt gtgaaacggt gaggttgcat ccagatgggg
     3001 tgtgtgactc taggactgag cttcagctct tctgtgtggt ttgtcattag tttttggtca
     3061 gaggtgttgt agccttacaa tctggatata ttttgcatta attttccaat gccgacattt
     3121 aattcctgct aagagcagag ctggtcaagt cgctggcttt ttttctgctc tcattttagc
     3181 ccatcaacca atgtttgtaa aagtggattg gtttgttgta gacaacttct ttttagtcaa
     3241 ctcacttttc tgagcagtca tcgttagaaa tggacaggca atagggctgc tctagtaaac
     3301 agaaagccat agggcaggca tcaggcttca gtgaaattac ttggggcctg gcgcatgagc
     3361 tagtgacatc gagtattcca tctgcttctc cctgtccgtt tgtcacacac tcggttttat
     3421 aactgtccaa ggtcaggcag agcaagcccc gctcacactc actgtgccca gggctctgtc
     3481 acgcacccct cgccagggct gctctggaac ctggtgtgcg cgtgcactgt attttaaatc
     3541 aagcagtgta agcactcatg tttgtctcag agtgaacttt tataacaaaa gagaaaattt
     3601 ggattttaat ttacaaatgg caaattattt atccctctgg atgcaccaaa gaccagtaaa
     3661 gtttatagct tttccatcta tatttataaa gcaatactgt attataaaaa tcactatttt
     3721 tatcacatgc ttgaaatttt tattttgttc tgttttaaaa atgtgcactc taaacatatc
     3781 agaaccttat ttcttcctat gaacttaagc tgcctgcgca caaaaaatat taaattatca
     3841 agtggagatg aagtagctgg cgtccctagg ctctaacagc ggagagaaag gaggggacaa
     3901 gttctgtatc ctgagtcgct gtgtgcttgg tcgataggct actcgctcac agagtccatt
     3961 ccaggtgtgt gtctgcggca gagactggca ccagcgttcc gaggcaggag agtgcccttg
     4021 ctctgggtag agtagccagc agacggaagc gtcccagcac tgccctcccc aggagtgtct
     4081 tggaggcact ggcaggctgg ctgaggctgt gcgtgtttgt actttagagt aggttcatgg
     4141 cttcttgtca ctgtacagca gctctctctg gccaagttgt aacactcagt ttctctggag
     4201 actgtcacag ttttacattt aaaaaaattt gcaa
//
