LOCUS       NM_133589               1867 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus protein phosphatase 6, catalytic subunit (Ppp6c),
            mRNA.
ACCESSION   NM_133589 XM_346651
VERSION     NM_133589.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1867)
  AUTHORS   Panier,S. and Durocher,D.
  TITLE     Push back to respond better: regulatory inhibition of the DNA
            double-strand break response
  JOURNAL   Nat Rev Mol Cell Biol 14 (10), 661-672 (2013)
   PUBMED   24002223
  REMARK    Review article
REFERENCE   2  (bases 1 to 1867)
  AUTHORS   Nasu-Nishimura,Y., Hayashi,T., Ohishi,T., Okabe,T., Ohwada,S.,
            Hasegawa,Y., Senda,T., Toyoshima,C., Nakamura,T. and Akiyama,T.
  TITLE     Role of the Rho GTPase-activating protein RICS in neurite outgrowth
  JOURNAL   Genes Cells 11 (6), 607-614 (2006)
   PUBMED   16716191
REFERENCE   3  (bases 1 to 1867)
  AUTHORS   Becker,W., Kentrup,H., Klumpp,S., Schultz,J.E. and Joost,H.G.
  TITLE     Molecular cloning of a protein serine/threonine phosphatase
            containing a putative regulatory tetratricopeptide repeat domain
  JOURNAL   J Biol Chem 269 (36), 22586-22592 (1994)
   PUBMED   8077208
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC078747.1.
            
            On or before Jan 12, 2005 this sequence version replaced
            XM_346651.1, NM_133589.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078747.1, BC063151.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840129, SAMN16676810
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1867
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q12"
     gene            1..1867
                     /gene="Ppp6c"
                     /note="protein phosphatase 6, catalytic subunit"
                     /db_xref="GeneID:171121"
                     /db_xref="RGD:708460"
     exon            1..173
                     /gene="Ppp6c"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..1016
                     /gene="Ppp6c"
                     /EC_number="3.1.3.16"
                     /note="PP-V; PP6C; protein phosphatase V"
                     /codon_start=1
                     /product="serine/threonine-protein phosphatase 6 catalytic
                     subunit"
                     /protein_id="NP_598273.2"
                     /db_xref="GeneID:171121"
                     /db_xref="RGD:708460"
                     /translation="MAPLDLDKYVEIARQCKYLPENDLKRLCDYVCDLLLEESNVQPV
                     STPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAK
                     WPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQIL
                     CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGA
                     KVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKD
                     VNTREPKLFRAVPDSERVIPPRTTTPYFL"
     exon            174..269
                     /gene="Ppp6c"
                     /inference="alignment:Splign:2.1.0"
     exon            270..335
                     /gene="Ppp6c"
                     /inference="alignment:Splign:2.1.0"
     exon            336..477
                     /gene="Ppp6c"
                     /inference="alignment:Splign:2.1.0"
     exon            478..557
                     /gene="Ppp6c"
                     /inference="alignment:Splign:2.1.0"
     exon            558..767
                     /gene="Ppp6c"
                     /inference="alignment:Splign:2.1.0"
     exon            768..1846
                     /gene="Ppp6c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggacgtgac gtaaggaggg ttccggcttc ggcctccgcc gctgcctccg ctactaccac
       61 cgccgccgct gctgttgccg cggcttgttc ttcctaaaat ggcgccactg gatctggaca
      121 agtatgtgga gatagcgcgg cagtgcaagt accttcccga aaacgacctg aagcggctat
      181 gtgactatgt ttgtgatctg ctcttggaag agtcgaatgt tcagcctgta tcaacgccag
      241 taacagtgtg cggggacata catggacagt tttatgatct ttgcgaactg ttcagaactg
      301 gaggtcaggt tcctgacaca aactacatat ttatgggtga ttttgtagac agaggttact
      361 atagtttgga gaccttcact tatcttcttg cactaaaggc taagtggcct gaccgtatta
      421 cacttttaag aggaaatcat gagagtagac agataacgca ggtgtacgga ttttatgatg
      481 agtgccaaac caaatatgga aatgctaatg cctggagata ctgtaccaaa gtttttgaca
      541 tgctcacagt agcagcttta atagatgagc agattttgtg tgttcatggt ggtttatctc
      601 ctgatatcaa aacactggat caaattcgaa ctattgagcg aaatcaggaa attcctcaca
      661 aaggagcatt ttgtgacctg gtatggtcag atcctgaaga tgtggacact tgggcaatca
      721 gtcccagagg agcaggttgg ctttttggag caaaagtcac aaatgagttt gttcatatca
      781 acaacttaaa actcatctgc agagcacatc agcttgtgca cgaaggctat aagtttatgt
      841 ttgacgagaa gctggtcaca gtgtggtctg ctcctaacta ctgctatcgc tgtggaaaca
      901 ttgcttccat catggtcttc aaagacgtca acacgagaga accaaagtta ttccgagcag
      961 ttccagattc agaacgtgtt attcctccca gaaccacgac gccgtatttc ctttgaggcc
     1021 tttgccatcc cgctggccac tttttgccct cttttacccc aactttcttg taccctctac
     1081 aatatacttt ttattgagca ctttgctgct gaaatgctgc ctcttgcctt tttttttaat
     1141 tttaaattat ctaactttat tgtttgttat ggtgtcaata gcagtgtttt tctatcagtt
     1201 ttgtcactca tcctatcccc acatggactc gtttgagaag acttgagaaa tgtcttaata
     1261 ctcacattgc tgcatgtagc tcttgcttgt ttgctgttct ggggagacag gaagcatctc
     1321 ttttttaaaa agccaattga caattacatg gaaatcctcc tcatttgtat cagctagcct
     1381 tttgtttttg tttggtagga tttaagaaat ttcagcagca aagttgtcca gtgggcagga
     1441 tggactgcat atgcctgagt catgtaccct tgtccaagct gtaaactcca ctgtcctttg
     1501 ttggatgata atttgatgtt ttaaaagggt ataaaataaa ttggtctaaa gggctgccct
     1561 ccttgttgtg tttttaaatt ttagttaaaa actgctacag ctatgacttt gtacattaag
     1621 ataattgtac tgatcttttt tcaaaaatct tgtatttttt aataaaataa tcttaaaacc
     1681 cagataggtt aagtgttaga aattttaaaa aatttacatt gttagctgaa agttactttt
     1741 tctttcttat gttttcttat tttttttttc tttttctttg ttgagttttt gaccctttgg
     1801 ttgagttaaa aatttcaatt aaaattcaat atttttttaa aaaaaaaaaa aaaaaaaaaa
     1861 aaaaaaa
//
