LOCUS       NM_001414974            4443 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus protein phosphatase 4, regulatory subunit 4
            (Ppp4r4), transcript variant 1, mRNA.
ACCESSION   NM_001414974 XM_039112757
VERSION     NM_001414974.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4443)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4443)
  AUTHORS   Chen,G.I., Tisayakorn,S., Jorgensen,C., D'Ambrosio,L.M.,
            Goudreault,M. and Gingras,A.C.
  TITLE     PP4R4/KIAA1622 forms a novel stable cytosolic complex with
            phosphoprotein phosphatase 4
  JOURNAL   J Biol Chem 283 (43), 29273-29284 (2008)
   PUBMED   18715871
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Dec 16, 2022 this sequence version replaced XM_039112757.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.37052.1,
                                           SRR26643298.36933.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-302               JAXUCZ010000006.1  128428009-128428310
            303-376             JAXUCZ010000006.1  128429644-128429717
            377-479             JAXUCZ010000006.1  128455777-128455879
            480-627             JAXUCZ010000006.1  128480102-128480249
            628-701             JAXUCZ010000006.1  128480659-128480732
            702-808             JAXUCZ010000006.1  128482787-128482893
            809-916             JAXUCZ010000006.1  128486393-128486500
            917-1038            JAXUCZ010000006.1  128490030-128490151
            1039-1161           JAXUCZ010000006.1  128491618-128491740
            1162-1331           JAXUCZ010000006.1  128492877-128493046
            1332-1451           JAXUCZ010000006.1  128493347-128493466
            1452-1529           JAXUCZ010000006.1  128496596-128496673
            1530-1613           JAXUCZ010000006.1  128497304-128497387
            1614-1796           JAXUCZ010000006.1  128498632-128498814
            1797-1902           JAXUCZ010000006.1  128501464-128501569
            1903-2050           JAXUCZ010000006.1  128502929-128503076
            2051-2195           JAXUCZ010000006.1  128505563-128505707
            2196-2237           JAXUCZ010000006.1  128506586-128506627
            2238-2312           JAXUCZ010000006.1  128506711-128506785
            2313-2382           JAXUCZ010000006.1  128508262-128508331
            2383-2469           JAXUCZ010000006.1  128509278-128509364
            2470-2563           JAXUCZ010000006.1  128510218-128510311
            2564-2634           JAXUCZ010000006.1  128512308-128512378
            2635-2788           JAXUCZ010000006.1  128515203-128515356
            2789-4443           JAXUCZ010000006.1  128517122-128518776
FEATURES             Location/Qualifiers
     source          1..4443
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..4443
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /note="protein phosphatase 4, regulatory subunit 4"
                     /db_xref="GeneID:500711"
                     /db_xref="RGD:1560932"
     exon            1..302
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..2813
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /note="isoform 1 is encoded by transcript variant 1;
                     serine/threonine-protein phosphatase 4 regulatory subunit
                     4"
                     /codon_start=1
                     /product="serine/threonine-protein phosphatase 4
                     regulatory subunit 4 isoform 1"
                     /protein_id="NP_001401903.1"
                     /db_xref="GeneID:500711"
                     /db_xref="RGD:1560932"
                     /translation="MHPPPPDAGVAMDFGQNSLFGYMEDLQELTIIERPVRRSLKTPE
                     EIERLTVDEDLSDIDRAVYLLSAGQDIQGASVIANLPFLMRQNPTETLRRVLPKVREV
                     LHVASVEMQITAAVSFLTILQEESMSVHTFAHSFLQVILLHLEHRDTGVSNAWLETLL
                     SAVELLPKETLRHEILNPLVSKAQLSQTVQSRLVSCKILGKLTNKFDAHSIKREILPL
                     VKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKNVVLPELIELSRDESGSVRLAAFET
                     LVNMLDMFDTDDRSQTILPLVKSFCEKSFKADESILISLSFHLGKLCHGLYGIFTPDQ
                     HLRFLEFYKKLCTLGLQQENGHNESQIPSQIVEQEKKYTSVRKNCAYNFPAMIVFVDP
                     KNFHMELYSTFFCLCHDPEVPVRYTIAICFYEVSKLLNSGVHLIHKELITLLQDESLE
                     VLDALINHLPEILELMSTGGENSVQENKFSSLPDLIPALTAAEQRAAASLKWRTHEKL
                     LQKYTCLPHIISSDQIYYRFLQRMFTIMMTNNVLPVQRAAARTLCIFLRYNRKQEQRH
                     EVIQKLIEQLGQGKSYWNRLRFLDTCEFIIEIFSRSFFCKYFFLPVIELTHDPVANVR
                     MKLCYLLPKVKSALKIPADMHLLQQLEMCVRKLLCQEKDKDVLAIVKKTVLELDRMEM
                     SMDMFQKKNYENDLLDQEKEREELLFLEMEQLEKEKHQNDGRLTSDKSFEKKRRDSRT
                     PTQSLSKNAAISVPGPSSSTPSTSKEIKKSKLTRSQSFNNQAFHAKYGTLDKCVSKSS
                     TLAHSSSVSGLVRTAMLSLTDDSFRTRNTSSVSVPANFSPNPVLPSTSRGPGNTADPK
                     SSGSKDAQPRKATLKSRKSNS"
     exon            303..376
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            377..479
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            480..627
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            628..701
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            702..808
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            809..916
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1038
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1161
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1331
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1451
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1529
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1613
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            1614..1796
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            1797..1902
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..2050
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            2051..2195
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            2196..2237
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2312
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            2313..2382
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            2383..2469
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            2470..2563
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            2564..2634
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            2635..2788
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
     exon            2789..4443
                     /gene="Ppp4r4"
                     /gene_synonym="RGD1560932"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtgcgctgc gctccggctc ccgccgcgct cgtgctctcg ccgcctgcgg cctcttgctc
       61 tgcttccccg cggccgagag cgggaccaga gagtccttct ggtgggcggc gcggggctgc
      121 gcgcgtccgg catcccgggg ccgctcgggc cgtccggcga gggagcccct cggcggtcca
      181 tgcatccgcc gccgcccgac gccggcgtcg cgatggattt cgggcagaac agcctgttcg
      241 gctacatgga ggacctgcag gaactcacca tcatcgagag gccggtccgc cggagcctca
      301 agacaccaga agaaatagaa agattgactg ttgatgaaga cctcagtgat attgacaggg
      361 ctgtttatct gctcagtgct ggtcaagata tccaaggagc aagtgtgatt gcaaatcttc
      421 catttttgat gcgacagaat cctaccgaga cacttcggag agtcttaccc aaagtcagag
      481 aagtcctgca tgttgcaagc gtggaaatgc agataacggc tgcagtgtcc ttcctgacca
      541 tccttcagga agaatcaatg tcagtccaca cgtttgcaca ctccttcctg caagtcattc
      601 tcctgcacct ggagcacagg gatacaggtg tcagcaatgc atggctggaa acacttctct
      661 ctgcagtaga attattgcca aaagaaaccc tgaggcatga gattctgaat ccacttgtgt
      721 ccaaggcaca gctttcccag actgtccagt cgcgtttagt tagctgtaag attttaggaa
      781 aactaaccaa caaatttgat gcccatagca ttaaaagaga aatacttccc ctggtaaaat
      841 cactctgtca agatgtggaa tatgaagttc gatcttgtat gtgtcggcag ttagaaaata
      901 tagctcaggg cattgggaca gaactgacaa agaatgtggt gcttcccgaa ttaatagaac
      961 tctctaggga tgagagtggc agtgtgcggc ttgctgcttt tgaaaccttg gttaacatgc
     1021 ttgacatgtt tgatacagat gacagaagtc aaactatact tcccttggtg aaatcattct
     1081 gtgaaaagtc tttcaaagca gacgaatcaa ttctgatttc tttatcgttt catttaggaa
     1141 agctatgcca tggactctat ggaattttca ctccagatca gcacttgaga tttttggaat
     1201 tttataagaa actttgtaca ctgggtttgc aacaagaaaa tggccacaat gaaagccaga
     1261 ttccatccca aatcgtagag caggagaaga aatacacttc agtacgaaag aactgtgctt
     1321 acaattttcc ggccatgatt gtttttgttg atcctaaaaa cttccacatg gaactctatt
     1381 ctacattctt ctgcctttgc catgaccctg aagtaccagt cagatacact attgctattt
     1441 gcttttatga agtatctaaa cttctgaatt ctggagtaca tttaatacac aaggaactga
     1501 taacattgtt acaagatgag tcactggagg tactagatgc tcttataaat cacctcccag
     1561 aaatcttgga acttatgtct actggtggag aaaacagtgt tcaggaaaat aagttctcct
     1621 cactgccaga cttgattcca gcactcacgg ccgctgagca gcgagctgca gcctctctga
     1681 agtggaggac ccatgagaag ctgctgcaga aatacacctg cctgcctcac atcatatcga
     1741 gcgatcagat ttattaccgt ttcttacaaa gaatgttcac catcatgatg accaataacg
     1801 tcttacctgt ccaaagagcc gcagcacgaa ctctgtgcat ttttctacga tataatcgca
     1861 aacaagagca gaggcatgaa gtcattcaaa agttaattga acagttgggt caaggaaaaa
     1921 gttattggaa tagacttcgc tttttggata cctgtgaatt tatcatagag atattttcca
     1981 gatcattttt ctgcaaatat ttctttctac ctgttattga actaacacat gacccagtgg
     2041 caaatgtgag aatgaaactt tgctacctgc tgcccaaagt gaagtccgct ctgaagatac
     2101 ctgcagatat gcatctcctc cagcagttag aaatgtgtgt gagaaaactc ctgtgtcaag
     2161 aaaaagataa agatgttctg gccattgtga aaaaaacagt attagagttg gacagaatgg
     2221 aaatgtctat ggatatgttc cagaaaaaaa attatgagaa cgatttgttg gatcaagaga
     2281 aagaaagaga ggaactgctg tttttggaaa tggaacagct agagaaggag aagcatcaga
     2341 atgacgggag gttgaccagc gacaaaagct ttgagaagaa acgcagagac tccaggacac
     2401 caacacagag cctgtccaag aatgcggcca tttctgttcc tggaccctct tctagcaccc
     2461 cgtcaacaag caaagaaatc aagaaatcca aattgactcg aagccaatct tttaataatc
     2521 aagcttttca tgcaaaatat ggcaccttag acaagtgtgt tagtaaaagt tccaccttag
     2581 cacactcgtc ttctgtctca gggctggtga ggaccgccat gctgtcacta actgatgact
     2641 cattccggac tcgcaatacc agtagtgttt ccgttccggc taacttttct cctaaccctg
     2701 tcttgcccag cacttcccgt gggccaggta acacagctga tccaaagagt agtggaagta
     2761 aagatgccca gccccggaag gctaccttaa aatccagaaa gtccaattct taagtcaact
     2821 gcttggtgaa ggagtcaagc agtcagcgga gacggtggaa gagctacagc gacggccagg
     2881 cttgttaaag tgtggaaggg aggaaggaat atggtgcagc tgatgtgaaa cttaccctat
     2941 ttggaattag atttccctag gaggtatgac aagggtttta atgaaggctc tgaatcccag
     3001 tgttccagtg cagggtaatg agctccaact tgaggtgtgt actgcctgct ggactgttag
     3061 agccgagcct gtctttaagt gagaggctgg cttttgttat gcaaagttgt agcatttaga
     3121 cattccatag cagtctaaat tagcctgctt gtctaaatcg actgcctggt aactacttgg
     3181 gctaggacac aggaggtaag gaaggcactg tatttcctgt gagctctcta ggcagagcag
     3241 aaaggtcaac cggagcagct gtctgtggtc ctatgggtcc tgggattctg cgatggtgtc
     3301 agcacctgga tggccccagt ctagattcag caatgaaaat ctgcagagat tcaggaaaac
     3361 tctagctaca aataccttta aaatgataga tgatgatttc cttaattcct agaatttctt
     3421 ttataaatgc tttgtttaca ttttagattg tatctgtcct taatgtcaaa tggtgaatcc
     3481 agttggaatc agctgttatt ccaagctatc atgctcacgc catgtcagca gtacccattt
     3541 gtacggatgc taatacttcc atcaaaattt gcctgtggaa catatattgt ccttaacttt
     3601 aaaatgtcat ttcctgagat agaatgtatg aagctattgt cagcttctct atttcaagtg
     3661 caatcagcat atatctatat tgataacaga aatacttgtt ttttaaagat atattgatgt
     3721 atgataaaga tgatctaatt tgtgaatgca tacgtgtgcg tggttacttt ttataatgtg
     3781 aagtggataa tgagcttatt taaaataaag cagaggttaa tgtgatacct gtacttgtga
     3841 gaaaagtttt aaatactttc ctacagtccc tactctataa agaaaaggca gttcatcttt
     3901 aagtaatgag ttggtggagg ataatggatc aactgtaaat gactcaggga cagtcactta
     3961 ttgcttcttt gttctttgtc accccttctt tccccatggc ctctctgggg cactgttcag
     4021 ggactcagtg ccttttatca gggacagtca gaagtgaaag cccaggagcc ctgagaaact
     4081 tgactgtcct gcctaaggaa attcagttta agtagtttgt gtctcctgct agtgttagac
     4141 atatggactt gaatctgttg tgttctggag aattcattgt gcacaagggg cagcgaggct
     4201 atgtcagttt tccagtattc tagttcacca tgccggcggc attgattctg tttacattag
     4261 acacaatgga gagtttcaat ttgattgtta aataatacac ttactactta taagcttttc
     4321 atattcctgt tatatatgtg ggataaagga aagtgacctg acagactagt caccactgct
     4381 tataaagttg gaagtcaatt gcttagtcat taaactctca attaaaacag tcattcaaaa
     4441 tta
//
