LOCUS       NM_001106740            6177 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Rattus norvegicus protein phosphatase 2 regulatory subunit B',
            epsilon (Ppp2r5e), transcript variant 3, mRNA.
ACCESSION   NM_001106740 XM_001080781 XM_216739
VERSION     NM_001106740.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6177)
  AUTHORS   Xu,H., Liu,T., Wang,W., Su,N., Yang,L., Yang,Z., Dou,F., Cui,J.,
            Fei,F., Ma,J., Wen,A. and Ding,Y.
  TITLE     Proteomic Analysis of Hydroxysafflor Yellow A Against Cerebral
            Ischemia/Reperfusion Injury in Rats
  JOURNAL   Rejuvenation Res 22 (6), 503-512 (2019)
   PUBMED   30712471
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473947.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001080781.1, XM_216739.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..6177
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..6177
                     /gene="Ppp2r5e"
                     /note="protein phosphatase 2 regulatory subunit B',
                     epsilon"
                     /db_xref="GeneID:299147"
                     /db_xref="RGD:1305657"
     exon            1..528
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     exon            529..692
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     CDS             536..1825
                     /gene="Ppp2r5e"
                     /note="isoform 2 is encoded by transcript variant 3"
                     /codon_start=1
                     /product="serine/threonine-protein phosphatase 2A 56 kDa
                     regulatory subunit epsilon isoform isoform 2"
                     /protein_id="NP_001100210.1"
                     /db_xref="GeneID:299147"
                     /db_xref="RGD:1305657"
                     /translation="MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIE
                     LTPLPLLKDVPTSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITI
                     SRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIR
                     FLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIR
                     KQINNIFLSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQVIRGLMKFWPKTC
                     SQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYI
                     MSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYK
                     SDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT"
     exon            693..889
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     exon            890..991
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1084
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1215
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1324
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1375
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..1495
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1623
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     exon            1624..1725
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..6177
                     /gene="Ppp2r5e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcattgacgg ggaccctgcg cgggtagcga acggcggctc tggcagcggc ggctcaggcg
       61 gctccaactc ttcctcccga ctcctgtgct tgctgccgct gcaaacccag gcttcctccc
      121 tcctccccct ccccgcgtcg ccgccgccgc cgccgccgcc gccgggtccg gtgcaacgag
      181 cagaggcgcc gcccgccggg aatgtgaacg aagagccgcc ggcggagccg caaccgggtc
      241 ggtgccgatt tgatgggacg ggcccgcgga ggaggctcgt gaggccgccg ctgccactgc
      301 cggagcgctg aggttcgggg ccagccgaga ggcctagaaa cactgccgct accgcggaac
      361 cggagggacg tcgccccgga cggccgtagt agcccggggc tctccgctgc tgcccggacc
      421 tccccctgtg cgtcccgggc cgccgcccgc ccccgccgcg gcccctagct cgcagcccac
      481 tccgcgcagc cacagatcat cttccgattc ttccccagga gcttcaagta gggatatgtc
      541 ctcagcacca actactcctc catcagtgga taaagtagac ggattttctc ggaagtccgt
      601 cagaaaagcc agacagaaga ggtcgcaaag ctcctcacag tttcggtctc aaggcaagcc
      661 cattgagctc acacctctgc cactgctgaa agacgttcca acctcagagc agcctgaact
      721 gttcctaaag aaacttcagc agtgctgtgt catttttgac ttcatggaca cgctatctga
      781 tcttaaaatg aaagaataca agcgctccac tcttaatgaa ctggtggact acattacaat
      841 aagcagaggc tgtctgacag agcagactta ccctgaagta gttagaatgg tgtcttgcaa
      901 tatattcaga actctccctc ctagtgacag caatgaattc gacccagaag aagatgaacc
      961 taccctcgag gcatcatggc cccacctaca gcttgtatat gaatttttca tacgattttt
     1021 ggaaagccaa gaattccaac ccagcattgc caaaaaatac atagatcaga aatttgtatt
     1081 acagcttttg gagctattcg acagtgaaga ccctcgagaa cgggactatt taaaaacagt
     1141 cttgcacagg atttatggca agtttctcgg gcttagagca tttatccgaa aacaaattaa
     1201 caatattttt ctaagtatta tcaatggctt cgctttacca cttaaggcag aacacaaaca
     1261 gttcctggtg aaagtgttga tccctttgca cactgtccgg agtttatcac tcttccatgc
     1321 ccaggttatt agggggttaa tgaaattttg gcctaaaaca tgcagtcaaa aagaggtcat
     1381 gttccttggg gagctggaag aaatcttgga tgtgattgaa ccatcacaat ttgttaaaat
     1441 ccaagaacct ttgtttaaac aaattgccaa gtgtgtttct agcccccatt ttcaggtggc
     1501 agaaagggca ctctattatt ggaataatga gtacatcatg agtttgatag aagaaaactc
     1561 gaacgtcatc cttcccatca tgttctccag cctttatagg atttcaaagg agcattggaa
     1621 tccggctatt gtggcgctgg tgtacaacgt gttgaaagca tttatggaaa tgaacagcac
     1681 tatgtttgat gagctgacag ccacatacaa gtcagatcgt cagcgtgaga aaaagaaaga
     1741 aaaggagcgt gaagaactgt ggaaaaaatt ggaggatctg gagttaaaaa gaggtcttag
     1801 acgcgatggg ataattccga cttaacagca gcctgacagc gacacactaa ccgtgggtca
     1861 cacgcttatg tagtagaagg atggagcaac cgttttctgt atcgtgcagc tttccagtag
     1921 atttcacatt gtctcattat tacagcagca ctgtatatac ctgtctctaa gtaaggactt
     1981 cagagtgtgg acagtagatg gactctcaga actttgcaaa cataatcatt gttctaaccc
     2041 tctttaaaaa caaacaaaca aacaaaaggt cacaggatct gtgggggaaa ttgctatgtt
     2101 aaaatcccat tatcaggagt tccttattta tcactagcag agagtatgat acaattttca
     2161 aatgtgaaca atcttaaatt tagcttgtct ttctgctaag ctgttaaatg tatttatagt
     2221 aaaggaagaa aagattgtca tttctttata agtttgtata gcgccctcct ctggacatga
     2281 ctgtaatgtg acatcctttc cttttgcaca tcttcatgag tcgaatgtcc acgtggaatg
     2341 gggctgtgaa tcacagaggt ccctgatgaa aggttgtctg tggggtgaac atcttcccag
     2401 cgactgggtg ttcctggtcc tcctttagtt ttcagattag gagtaaaaag aagaggtgat
     2461 aagcatggta gcaaagggaa gccgggcttc gttcctatca gatgtgctga gtccaaatca
     2521 gtgtcttgaa tcctttgaaa acaggcagtg gagcgcagca gccccgcccg cacctgcggc
     2581 atcggctgca gacgtcggtg tgcatccaga ccagagacaa tttagaaacg tccgagaaca
     2641 tccttttggc tcctatgaag taagacagac agaacactaa gcgatagaac cgtgaagctg
     2701 agcaccagga ctgcggtctg gctgggaccc gagaggagtg aacagcatga agtgtttgga
     2761 gttgatgcct tactttctaa tgtgtactta cagagggttt cagcacaagc gggtgcagcc
     2821 tctgggagaa gcagaacatg ctccagcggt tgttgtcgat tcttgttcta tagctcatcg
     2881 cagcgccagc cctgttttta gccagaaagg attcaggatc aacattatgc gttctgaatt
     2941 ggatgcatat tcctaactac tgtatttgtt accaaaagtg gttctacaaa tgctactgaa
     3001 aaaaatctgg aaattcctaa tgtcctgagt attaataata aagtttaaaa aaatgctttt
     3061 atatcaaagg tgcattgtga ccaaattgtt taagcaaaaa aaaaaaaaaa aaaaaaaaaa
     3121 aaggaaaacg agggctgtgc tctagatgta cttactggtt ctctgtgtta acgggagacc
     3181 ccacaggggt aggaaaatcg tgacgtacgg ctgtgcagtc tgtatttacc cgatgtggtt
     3241 gcattgctgt gtactggcaa atgtgtgttg tgaggtttgt ttccaggcag gcagcttttg
     3301 cttgttagcg acaggacacc agtgagccag tcaccctgaa ccatcacgcc caacagtgct
     3361 catggcgtag ccgcctctgt gttcatagtt gagttgtgat tatagctaac acgaacacac
     3421 atgagctgtt gttgctctta gtagaaatac actataaata tgagcttgtg tattttcttc
     3481 cttttaaatg taaattagaa tatacagagc ttcgatgttt ccaaggaaaa ggagggggag
     3541 gccactgacc tttgtcactt atgaagtgtt cccagattgt cagtcacagt gtgtacccaa
     3601 gagtaagcta atcatgggta ttttcactta ggtaccttgg tcttttgttt ttaaaggttt
     3661 gcataccacc aagtccagga cggtctgtgg aatgaatagg ggcatttaag agcattaagg
     3721 agggctccat atgagtgcct gggaagtgtg ggcgcagagc tgcgagccca catgttggtg
     3781 ccgagccgtc agcccatagc acatctcctt cagctgtctt aggcatcttg atcctcatta
     3841 cacagatctg atagcataga ctgcgcttgc tgtaacccct catgccgggg tgaaacatgc
     3901 tcatttgaca tgagaaaggc caggacctct tcctgcacct tgtcctgtcc ttggagctaa
     3961 ggaccagcag cactggcact caatctgtta gttctgtctg ttggtccttc ccaactgaga
     4021 ggagtaaagc taagctttag actatttaaa ggtatgacga gggctgtctg tctctctgtc
     4081 tcaactcaca gggcacgctc tgagaagaaa cactcatttt cctttttaac caaaagtgat
     4141 aatgtgaccg cggtcatgtt gtgtgtgctg atgagaagct agcccaggta acttgattgt
     4201 tgcactatgt gacatattta aagacgtact tgctgcattt gcagcagccc cctgtctgac
     4261 accccccacc ccccgcaatc ctgctgtcac tcagtgtgag ttaactgcga cagactcagc
     4321 tctgtgttat attttgtttg cttcatagtt tccagaatta tatataaata tattttttca
     4381 atagcgaata ttatagttag tgagtggtga ccactccaac cttatcccta accatattgg
     4441 tgtcagggat ggaactaaga gtgttctagg aataaaagtt aagataaaac cctgtgattt
     4501 aggatgccgc cggggttgcg ggctgcaggc ctgcagcagc tgtgtgagtg aagtgaccgt
     4561 ctcctctgga tcaagcgtcc actcctcgtt gtgcccatgt cccagggctc cttcatcact
     4621 gtttagtttc tgcccgctgc aattttgatt atattttgct cttcctgaca ttgactgttg
     4681 tttttaaata aaagagaata aaaaatgaat gaatactccc ctgaatgtga ctggctgcag
     4741 gagcaggggt aagctcctcc tcctcaggct cttcccctaa ggggcaggat cacactgatt
     4801 ctgtgcatcc tgtgcatgca tcagcccaag atacagacct ggggagcacc tgtaatcaca
     4861 cctcccatac tgaacacata tgaacgtatc ctggggctca gtcacaccgt ggaaagggga
     4921 ataaagtata ccaagagctt taaaagctgt tttaagtttt tgtagggatg gggctgggga
     4981 gtggtgtgtg gtcgggggtg ggggtggggc tggtatcggc accattaagt agtccaaagg
     5041 tcaatttctt cctgctttgt tttccctttt aattggatat actgacctgg cccagagaag
     5101 gaagagcttc tctctctgat gttattaacc tacgtttcca caaagtgaca gtcacctgtc
     5161 tcagaaaggg caggagatat gatcagtgat gttttatttg cacatgaata ttttattttt
     5221 gtactctggc tcagctgctt ctctgtgggg agttagggag gagccataaa ggacttttgt
     5281 atatcggcga cacattttat attcctctac atctattctg agaacccaaa aggagggctt
     5341 ctgcgtcctg aggaggatga gcagggcttg agctagcgga atgttccttt gtgctgctgc
     5401 ttgtgcacga tagcggctgt ggcatctctc ctggaaacca acaccccgta ctgtgatgtc
     5461 tatgaatata ggtttccttt tctcccctcc tctcttcccc atcctctcct ctcctatctc
     5521 aacctatccc ttttttaaaa aaacaaacaa accacttact gtaaataagt tgtaatctaa
     5581 acctcatgta tcaatggggg actttcaaat ataaatatta ccaatacatt ttcttgttgt
     5641 ctgggttttg attggagtct aatgagaatg gcgtgtccat tcccatagtc ttaaggattc
     5701 catctccact ccagcctctc ctgttcctca tttcatcgtt gtggcaggag agggcagcaa
     5761 acgttcattt ttccccactg ggaagccgca catttagctg tgggtgagtg tgttactctg
     5821 tttttcaaaa cagcatctgt gcatagatgt aaaaatgaaa caatatgaaa agttgcatat
     5881 gaagattaca gactggctaa tcaggcaggg aagccttctg atccacttca aagtaaaaaa
     5941 aaaaaaaaaa aattaatcta agacacttcc aggccctgtt gaaccagatc cttgtcagac
     6001 agcaggatgc agatggcagc ttacacactt ggaaataagg gttcatcttt gaaaatactc
     6061 acacaaaagt ggttacggac taagcaaagg tgctccccaa agcactgtaa ttcgctctct
     6121 ctcagctgtg tgagattctg taccgtgggg gtccctaata aataagcagg ggaggat
//
