LOCUS       NM_001107911            1793 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus protein phosphatase 1, regulatory subunit 8
            (Ppp1r8), mRNA.
ACCESSION   NM_001107911 XM_001064335 XM_232739
VERSION     NM_001107911.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1793)
  AUTHORS   Van Eynde A, Nuytten M, Dewerchin M, Schoonjans L, Keppens S,
            Beullens M, Moons L, Carmeliet P, Stalmans W and Bollen M.
  TITLE     The nuclear scaffold protein NIPP1 is essential for early embryonic
            development and cell proliferation
  JOURNAL   Mol Cell Biol 24 (13), 5863-5874 (2004)
   PUBMED   15199142
REFERENCE   2  (bases 1 to 1793)
  AUTHORS   Llorian M, Beullens M, Andres I, Ortiz JM and Bollen M.
  TITLE     SIPP1, a novel pre-mRNA splicing factor and interactor of protein
            phosphatase-1
  JOURNAL   Biochem J 378 (Pt 1), 229-238 (2004)
   PUBMED   14640981
REFERENCE   3  (bases 1 to 1793)
  AUTHORS   Trinkle-Mulcahy L, Sleeman JE and Lamond AI.
  TITLE     Dynamic targeting of protein phosphatase 1 within the nuclei of
            living mammalian cells
  JOURNAL   J Cell Sci 114 (Pt 23), 4219-4228 (2001)
   PUBMED   11739654
REFERENCE   4  (bases 1 to 1793)
  AUTHORS   Boudrez A, Beullens M, Groenen P, Van Eynde A, Vulsteke V, Jagiello
            I, Murray M, Krainer AR, Stalmans W and Bollen M.
  TITLE     NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a
            regulator of pre-mRNA splicing and mitotic entry
  JOURNAL   J Biol Chem 275 (33), 25411-25417 (2000)
   PUBMED   10827081
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_232739.3, XM_001064335.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC162025.1, CV077224.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1793
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1793
                     /gene="Ppp1r8"
                     /note="protein phosphatase 1, regulatory subunit 8"
                     /db_xref="GeneID:313030"
                     /db_xref="RGD:1306280"
     exon            1..69
                     /gene="Ppp1r8"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..1069
                     /gene="Ppp1r8"
                     /note="protein phosphatase 1, regulatory (inhibitor)
                     subunit 8"
                     /codon_start=1
                     /product="nuclear inhibitor of protein phosphatase 1"
                     /protein_id="NP_001101381.1"
                     /db_xref="GeneID:313030"
                     /db_xref="RGD:1306280"
                     /translation="MAAAVNSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIID
                     EKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLE
                     PHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEE
                     TELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSDDDEIINPEDVDPS
                     VGRFRNMVQTAVVPVKKKRMEGSGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEPGS
                     QPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVTINPTPNPAVYNPEAVNEPKKKK
                     YAKEAWPGKKPTPSLLI"
     exon            70..130
                     /gene="Ppp1r8"
                     /inference="alignment:Splign:2.1.0"
     exon            131..284
                     /gene="Ppp1r8"
                     /inference="alignment:Splign:2.1.0"
     exon            285..505
                     /gene="Ppp1r8"
                     /inference="alignment:Splign:2.1.0"
     exon            506..650
                     /gene="Ppp1r8"
                     /inference="alignment:Splign:2.1.0"
     exon            651..715
                     /gene="Ppp1r8"
                     /inference="alignment:Splign:2.1.0"
     exon            716..1793
                     /gene="Ppp1r8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggagacgc aagatggcgg cagccgtgaa ctccggctcc agcctcccgc tgttcgactg
       61 cccgacttgg gcaggtaaac cgccaccagg cttacatctg gatgtagtga aaggagacaa
      121 gctaattgag aagctgatta ttgatgagaa gaagtattat ttatttggga ggaaccccga
      181 tctgtgcgac tttaccatcg accaccagtc ttgctctcgg gtccacgcag cactggtgta
      241 ccacaagcac ctgaagagag ttttcttgat agatctcaac agcacacatg gcactttttt
      301 gggtcatatc cggctggaac cgcacaagcc tcagcagatt cccattgact ccacggtctc
      361 gttcggcgcg tccacgaggg cgtacactct gcgagagaag cctcagacac tgccatcggc
      421 tgtgaaagga gatgagaaga tgggcggaga ggacgatgaa cttaagggct tgttgggact
      481 tcctgaggag gagaccgagc tggataacct gacagagttc aacactgccc acaacaagcg
      541 gatttcaacc ctcactattg aagagggaaa tctggacatt cagagaccaa agaggaagag
      601 gaagaactcg agggtgacct tcagtgatga tgatgagatc atcaacccag aggatgtgga
      661 tccgtctgtt ggtcgcttcc ggaacatggt gcagactgca gtggttccag tcaagaagaa
      721 gcggatggag ggctcaggct ccctgggcct ggaggagtca gggagcaggc gcatgcagaa
      781 ctttgccttc agcggaggac tatacggggg cctgcccccc acacacagtg aaccaggctc
      841 ccaaccacat ggcattcacg ggacagcgct cattggtggc ttgcccatgc catacccgaa
      901 cctcgcccct gatgtggact tgactcctgt tgtgccgtca gcagtgacca taaatcccac
      961 accaaacccc gcagtgtata accctgaagc tgtaaatgaa cccaagaaga agaaatacgc
     1021 gaaggaggct tggcccggca agaagcccac gccttcctta ctgatttgat atttttggtt
     1081 atggagaggg tggggagggc tggggagggt ggaggggtga caaggggagc tactgaacta
     1141 gggagaaaac tttccatgtg tgcagtatcg tctttgagaa agtctcctaa ggccctaacc
     1201 atgtaatact gagactaggg gcggggctag aggaccagta aagacctgag tcagaacact
     1261 gaagtgcaga gaaaggctgc ccaggccttc tgagcagact gtcctggccc tctcccagtg
     1321 gagaggtcct gtcctgtctg gtggcatgag gccagtttgt aaccagtgtc acaggacagg
     1381 ctaatgggtt tgtacagtgt tgctggacgt tacctagttt ccttgtccac attgagaact
     1441 catttagttc cactgcagcc tcccctgtgg cctcgctgtt tacgggtgcc atgaggcagt
     1501 tccttaagga gtgacccgtt ggggcagttc tggtggacag gaagactact ttgcagggac
     1561 cgggtgttgt taggagaaga cactcaggca ttggtttgga ggctcccctg acccccatgg
     1621 agagttctgg ttattcaaat ctccagaata gacctggtta acaggagaca aggtaggaac
     1681 cattgtatga gctttgtaca gatttgtaca tttgtgtaat aggccttttc tgctttaagt
     1741 gtagcttttt acctgtcacc tttattacat tgtaaattaa atgtaacttt tgt
//
