LOCUS       NM_133425               2787 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Rattus norvegicus protein phosphatase 1, regulatory (inhibitor)
            subunit 14c (Ppp1r14c), mRNA.
ACCESSION   NM_133425
VERSION     NM_133425.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2787)
  AUTHORS   Liu,Q.R., Zhang,P.W., Zhen,Q., Walther,D., Wang,X.B. and Uhl,G.R.
  TITLE     KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by
            morphine
  JOURNAL   J Biol Chem 277 (15), 13312-13320 (2002)
   PUBMED   11812771
  REMARK    GeneRIF: regulation by morphine
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF407168.3.
            
            On Nov 23, 2006 this sequence version replaced NM_133425.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF407168.3, BC086978.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2787
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p11"
     gene            1..2787
                     /gene="Ppp1r14c"
                     /gene_synonym="Kepi"
                     /note="protein phosphatase 1, regulatory (inhibitor)
                     subunit 14c"
                     /db_xref="GeneID:171010"
                     /db_xref="RGD:620538"
     exon            1..907
                     /gene="Ppp1r14c"
                     /gene_synonym="Kepi"
                     /inference="alignment:Splign:2.1.0"
     CDS             605..1099
                     /gene="Ppp1r14c"
                     /gene_synonym="Kepi"
                     /note="kinase-enhanced PP1 inhibitor; PKC-potentiated PP1
                     inhibitory protein"
                     /codon_start=1
                     /product="protein phosphatase 1 regulatory subunit 14C"
                     /protein_id="NP_596916.1"
                     /db_xref="GeneID:171010"
                     /db_xref="RGD:620538"
                     /translation="MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSR
                     EDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEE
                     EEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQ
                     KKSV"
     exon            908..991
                     /gene="Ppp1r14c"
                     /gene_synonym="Kepi"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1024
                     /gene="Ppp1r14c"
                     /gene_synonym="Kepi"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..2784
                     /gene="Ppp1r14c"
                     /gene_synonym="Kepi"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1173
                     /gene="Ppp1r14c"
                     /gene_synonym="Kepi"
     polyA_site      2550
                     /gene="Ppp1r14c"
                     /gene_synonym="Kepi"
     polyA_site      2770
                     /gene="Ppp1r14c"
                     /gene_synonym="Kepi"
ORIGIN      
        1 ggcatctgtg gtggtcatgg cgtgaatagg aatgtgtgtt aggagcagcg gggtggggcc
       61 gaaggagagg ggaggagaca ctaccagcca tcctgggaga gccaagatga gaggatccca
      121 cagcgcggtc atttcccacg acctttacct ggtgggacag agctgatcca gactgaggga
      181 gtcgacagat ttcgtgcgcc ccaaggttgc tcgagaagca cagttcgcgt ctgcagggca
      241 agtgacgcgg acgcccgcct agaggaccga ctgcccctgc cacccagacg atccacgcca
      301 atcttctccc tggactacac agcccctcgc cggcctgttc ccgggcacag attctccacc
      361 tcggacgact tccaagccta gggcggtctc tggggctgga gcatcggggt ccttggaggc
      421 gtctttaagg ctttggtctc cgccctcctc ccttctgcct cctccctcct ctaggatcca
      481 gtggctagga gcgcggagca ggtgcgggcc gtcgtatgca gctgcccggg ccgcggaggt
      541 agtggcgcgg ggcgctcgcc tgccccttct ccgggccact ctcagggctc cggcgctcgg
      601 ggacatgtcg gtggtgaccg gcggcggtga ggcggccggc gggacaagcg gaggcggcgc
      661 gcgagtcttc ttccagagtc ctcgcggggg caccggcggc agccgggaat ccagcagcca
      721 ctccggctcc tcaagggagg attcggcgcc ggtggccaca gtggcagccg ctgggcaagt
      781 gcaacagcaa cagcgccgcc accagcaggg aaaagtgaca gtgaaatatg accgtaagga
      841 gcttcggaag cggttggtgc tggaagaatg gatcgtggag caactgggtc agctgtatgg
      901 ctgcgaggaa gaagaaatgc cagatgtaga aattgatatt gatgatcttc ttgatgctga
      961 cagtgaggag gaaagagctt caaaattaca ggaagctctt gtagactgct ataaaccaac
     1021 agaggaattt atcagagagc tgctctcccg gataagaggc atgaggaagc tgagccctcc
     1081 acagaagaag agtgtatgat tttgcaacag ggtaaaattc tctcggagat gaagaaagtg
     1141 acctgggatt tggactccac agatactttt attaaaaaaa aataaccata gttgtctttt
     1201 acaacaacat tttttggtgt gtatgtgtgt gtggggaggg ttagacattt attcaaaagt
     1261 gttccttctt ttgttgtttt aaagggtttt cattactgta atattttaat ggcaaagcta
     1321 ctatagcttg gactgtagtc caaccaagga ctgtcaaagc agatgcatcc acaaggatgg
     1381 gcaatgcttt ctataagaac tcagccataa tttaggatct tacagggaag atggctttct
     1441 tacagtcaga ttggtaagac ggttttaagt tatacatttg acttagatgt caaaaatatc
     1501 ccatgcttgt acatatctac aaacactaaa aatagagagg agaactttat atcaggttca
     1561 tggaataagc ctgtgtttgt cgtgttagac atggtcacaa cacatgtttc cgtaaagccc
     1621 ccaggcattc ttcagacaaa tgtggtccac cttcagcatc cactttctgc gctaaagtga
     1681 aagaattcca catgttcgtt tttataatga gccatactac acacgcgttg agttggtcaa
     1741 gggcttaatt cgtaaatttt gtttcattag ttgagatgct tggccaggta ttgcctcgtt
     1801 gtggtttttt aaggttttat gaactcttaa ttttgaaaac tagcctgatt cataaagaaa
     1861 tgcctacact tcctgaacag agttttgcaa tggagaaagg aagccctgtg taacaacgag
     1921 ttttctgctt tcagtgcaat acgctatact atctctgtcc atgaaagcag gacaaaaaga
     1981 aactaacaaa cagattgagc ctcttccttc ttagaagtag atcctggcct cttctgtgct
     2041 ggttccaaca atccagaagc atgaactgag tattaagaaa tgtagagatg ggaagacacg
     2101 ttaagatctt tgttagttca gatgtctggc ttcgtctctg gtttctctca gtgcttcatg
     2161 gtcctgattg tgaccttgat ttccatgtta ggagctaggt ttgactacct accttaaccc
     2221 tacagttaca taccagctct ttgagtagaa tgaaaattca tatgggatgt aggcagggtg
     2281 aaaactgagt aaaagccctt ccttccagga agccccgctg cctccccctg gaaaccctgt
     2341 ctgccataag aagtctccag gtgaccctgt ctgaaaacag ggaccaggca atttatatca
     2401 agggtgcttt aaacatattt tattttttaa aagaactatg tttgtgaatt ttctgtatac
     2461 tggcaagctt ttgaaaatgt atttaatttt gtaatgttta ccaatgattt atttacaagc
     2521 tatttactca aataaaggga gctgcttaca agcttgtttg tgcgtgtgac agtacaacat
     2581 acagggtggg ggcggcgttt ggtgcgttct ctgcagatgg gaatcccaag cgcccaatgg
     2641 agctaacctc tcattttcca agcatttagt cctgatgctt atctcggtgt cttcagcaga
     2701 gaacccagtc atgttcttgg attaataaag agacaaaagt gtactcacac aaaataaata
     2761 aaatctttgt aaaaaaaaaa aaaaaaa
//
