LOCUS       NM_001395106            4582 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus protein phosphatase 1, regulatory subunit 13B
            (Ppp1r13b), mRNA.
ACCESSION   NM_001395106
VERSION     NM_001395106.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4582)
  AUTHORS   Wilson,A.M., Morquette,B., Abdouh,M., Unsain,N., Barker,P.A.,
            Feinstein,E., Bernier,G. and Di Polo,A.
  TITLE     ASPP1/2 regulate p53-dependent death of retinal ganglion cells
            through PUMA and Fas/CD95 activation in vivo
  JOURNAL   J Neurosci 33 (5), 2205-2216 (2013)
   PUBMED   23365256
REFERENCE   2  (bases 1 to 4582)
  AUTHORS   Beckerman,R. and Prives,C.
  TITLE     Transcriptional regulation by p53
  JOURNAL   Cold Spring Harb Perspect Biol 2 (8), a000935 (2010)
   PUBMED   20679336
  REMARK    Review article
REFERENCE   3  (bases 1 to 4582)
  AUTHORS   Samuels-Lev,Y., O'Connor,D.J., Bergamaschi,D., Trigiante,G.,
            Hsieh,J.K., Zhong,S., Campargue,I., Naumovski,L., Crook,T. and
            Lu,X.
  TITLE     ASPP proteins specifically stimulate the apoptotic function of p53
  JOURNAL   Mol Cell 8 (4), 781-794 (2001)
   PUBMED   11684014
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.37626.1,
                                           SRR26643298.37337.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-269               JAXUCZ010000006.1  136783708-136783976 c
            270-417             JAXUCZ010000006.1  136750650-136750797 c
            418-537             JAXUCZ010000006.1  136748512-136748631 c
            538-614             JAXUCZ010000006.1  136744365-136744441 c
            615-716             JAXUCZ010000006.1  136732783-136732884 c
            717-891             JAXUCZ010000006.1  136730128-136730302 c
            892-1088            JAXUCZ010000006.1  136728869-136729065 c
            1089-1229           JAXUCZ010000006.1  136726091-136726231 c
            1230-1410           JAXUCZ010000006.1  136723131-136723311 c
            1411-1577           JAXUCZ010000006.1  136719627-136719793 c
            1578-2079           JAXUCZ010000006.1  136718828-136719329 c
            2080-2846           JAXUCZ010000006.1  136717172-136717938 c
            2847-2984           JAXUCZ010000006.1  136716521-136716658 c
            2985-3118           JAXUCZ010000006.1  136716315-136716448 c
            3119-3285           JAXUCZ010000006.1  136714956-136715122 c
            3286-3485           JAXUCZ010000006.1  136713841-136714040 c
            3486-4582           JAXUCZ010000006.1  136711834-136712930 c
FEATURES             Location/Qualifiers
     source          1..4582
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..4582
                     /gene="Ppp1r13b"
                     /note="protein phosphatase 1, regulatory subunit 13B"
                     /db_xref="GeneID:314465"
                     /db_xref="RGD:1304651"
     exon            1..269
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..3527
                     /gene="Ppp1r13b"
                     /note="protein phosphatase 1, regulatory (inhibitor)
                     subunit 13B"
                     /codon_start=1
                     /product="apoptosis-stimulating of p53 protein 1"
                     /protein_id="NP_001382035.1"
                     /db_xref="GeneID:314465"
                     /db_xref="RGD:1304651"
                     /translation="MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGGCH
                     LAEVWRGSERPIPCDHMMYEHLQKWGPRREEVKFFLRHEDSPTESSEQGARQSQEQRT
                     QRNVMNVPGEKHTENGVGNPRVELTLSELQDMAARQQQQIESQQQMLVAKEQRLHFLK
                     QQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFS
                     AMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSYNGRLTGPAAVELKRLYQELQ
                     IRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQ
                     SPLSTSGRVAAVGPYIQVPSTGGFPLPGDPVKPQSLTIASSAAHGRSKSANDGNWPTL
                     KQNSASVKSTQMAGGDWKDSGMEGTLKQGAISSQPLPLSALGATDKLGIEIGKGPPPI
                     PGVGKPLPPSYGTYPSPGPLGPGSTSSLERRKEGSLPRPAAGPPSRQKPAPLPPAGSA
                     PQPSSSQQIQQRISVPPSPTYPPAGPPAFPAGDGKPELPLTVAIRPFLADKGSRPQSP
                     RKGPQTVNSSSIYSMYLQQATPPKNYQPPAHGTLNKSVKAVYGKPVLPSGSASPSPLP
                     FLHGSLGTGTTQPQPPSECAEKEAEPEGPSVPGEGSTVESLPRPLSPTKLTPIVHSPL
                     RYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTP
                     FYQPSPSQDFVGTLADVDNGNTNANGNLDESFPPRPTAPLPDELAPSSDANDNELPSP
                     EPEELICPQTTHQTAEPTEDNNNNVATVPSTEQIPSPVAEAPSEEDQVPPAPLSPVVH
                     PPTASASKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSK
                     PNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLV
                     ESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGIVYALWDYEA
                     QNNDELSFHEGDAITILRRKDENETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA
                     "
     exon            270..417
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            418..537
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            538..614
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            615..716
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            717..891
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1088
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1229
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1410
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            1411..1577
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..2079
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            2080..2846
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            2847..2984
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            2985..3118
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            3119..3285
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            3286..3485
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
     exon            3486..4582
                     /gene="Ppp1r13b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcggggcc tccgcagcct gcgggggtga gccgagtggg tggcggaagg cggccggctt
       61 cagcagaggc ggcggtggcg gctgagggac ggcgacgcgg ctcgcggggc ggcgcgacag
      121 gacgagcgag agctgcgtgg ctctccgcag ctgccgcctc gccgcagccg ggccgcaggg
      181 cgccgcagcg ggtgcgcggc ctgtgaggcg gccggagagg cgtcctgtca ggcggcgcgg
      241 gcgcggcgga cggcgccgcg atgatgccga tgatattaac cgtgttcttg agcaacaatg
      301 aacagatttt aacagaagtt cctataacac ctgaaaccac ctgtcgagat gtcgtagaat
      361 tctgcaagga acctggagag ggcggctgcc acctggccga agtgtggaga ggaagtgagc
      421 gtcccatccc ctgtgaccac atgatgtatg agcacctaca gaagtggggg cctcgcaggg
      481 aagaggtaaa attttttctt cgccatgagg attctccaac tgagagcagt gaacaaggtg
      541 cccgtcagag ccaagagcag agaacgcaga gaaacgttat gaatgttcct ggagagaagc
      601 acactgaaaa tggggttggg aacccacgtg ttgaacttac cctctcagaa cttcaagaca
      661 tggcggccag gcagcagcag cagattgaga gtcagcagca aatgctggtt gccaaggaac
      721 agcgtttaca tttcctaaag caacaggagc gccgccagca gcagtccatt tctgagaatg
      781 agaagcttca gaaactgaag gaacgagtgg aagcccagga gaacaagctg aagaagatcc
      841 gggccatgag aggacaagtg gactacagca aaatcatgaa tggcaatctg tctgctgaga
      901 ttgaaaggtt cagcgccatg ttccaggaaa agaagcagga agttcagact gccatcttac
      961 gagtcgatca gctcagtcag caactagaag atttaaagaa aggaaagctg aatgggttcc
     1021 agtcatacaa cggcaggttg acagggccag cagcagtgga gttaaaacga ctctaccaag
     1081 agctgcagat tcgtaaccag cttaatcagg agcagaattc caagctccag cagcagaagg
     1141 agctcctgaa caagcgcaac atggaggtgg ccatgatgga taagcggatc agcgagcttc
     1201 gtgagcgcct ttacggcaag aaaatccagc tgaaccgtgt gaatgggaca tcatcaccac
     1261 agtcacccct gagcacatcc ggccgggtcg ctgctgtggg tccttatatc caggttccca
     1321 gtactggcgg gtttcctctc ccaggggatc ctgtaaagcc ccagtctctc accattgcct
     1381 cgagtgctgc ccacggaaga tccaaatctg ctaatgatgg aaactggcca acgttaaagc
     1441 agaattctgc ttcagtgaag tcaactcaga tggctggtgg ggactggaag gactcaggca
     1501 tggaggggac cctaaagcaa ggtgccatct caagccagcc tttgcctctg tccgcactgg
     1561 gagctacaga caagctgggc atcgagattg gcaaagggcc acctcccata cctggtgtag
     1621 gcaagccact tcccccaagt tatgggacat atccaagccc tgggcccctg ggcccagggt
     1681 caacaagctc cctggagagg aggaaagaag gaagcttgcc cagacctgct gcaggcccac
     1741 cgagtcggca gaagcccgcc ccactgcccc cagctggcag cgctccccaa cccagctcct
     1801 cacagcagat tcagcagagg atctcagtgc caccaagtcc cacataccca ccagcggggc
     1861 cccctgcctt cccagctgga gacggaaaac ctgagctgcc actcacagtg gccattaggc
     1921 ctttcctggc tgataaaggg tcaaggccac agtctcctag gaagggacct cagacagtaa
     1981 actcaagctc tatatactcc atgtacctcc agcaagccac gccacctaag aattaccagc
     2041 caccagctca tggcacccta aacaagtcag ttaaagcagt gtatggtaaa cctgtcctac
     2101 cgtcagggtc agcgtctcca tcgcccttac cgtttcttca tgggtcgctg ggcacaggca
     2161 cgacacagcc gcagccacct tcagaatgtg ctgagaagga ggcagagccg gaaggcccca
     2221 gcgtgcctgg agaaggcagc acggtggaaa gcctgccacg gccgctcagt cccaccaaac
     2281 tcacacccat tgtacactcc ccactccgct accagagcga tgcggacctg gaagctctcc
     2341 gcaggaagct ggccaatgca ccccgacccc tgaagaagcg cagctctatc acggagccag
     2401 agggccctgg agggcccaac attcaaaagt tgctttatca acgcttcaac accctggctg
     2461 gcggcatgga gggtacccct ttctaccagc ccagcccgtc acaggacttt gtgggcacct
     2521 tagctgatgt ggacaatgga aacaccaatg ccaatggcaa cttggatgag tctttccctc
     2581 cccggcccac ggccccactt cctgatgagc ttgccccatc ctcagatgcc aatgacaatg
     2641 agttaccttc ccctgagcca gaggagctca tttgtcccca gacaactcat caaactgctg
     2701 agcccactga ggacaataac aacaacgtgg ccacggtacc ctccacagag cagatcccaa
     2761 gtcctgtggc tgaggctcct tccgaggagg atcaggtccc tcctgcacct ctttcccctg
     2821 tcgtccatcc tccaacagcg tccgcgagca agcggaccaa cctgaagaag cctaactctg
     2881 agcggacagg gcatgggctg agagtgcgct tcaaccccct ggcactgctt ctagatgctt
     2941 ctctggaagg agagtttgat ctagtgcaga ggatcatcta tgaggtggaa gaccctagca
     3001 aacccaatga cgaagggatc acccccctac acaatgctgt ctgtgctggc caccaccata
     3061 tcgtgaagtt tctgctggac tttggtgtca atgtgaatgc tgcagacagt gatggatgga
     3121 caccactgca ctgtgccgcc tcttgcaaca gtgtccacct ctgcaagcag ctggtggaga
     3181 gtggagccgc tatctttgcc tccaccatca gtgacatcga aaccgctgca gacaagtgtg
     3241 aggagatgga ggagggctat atccagtgtt ctcagttcct gtacggggta caagagaagc
     3301 tgggggtcat gaacaaaggc attgtgtatg ctctgtggga ctacgaagcc cagaacaatg
     3361 atgagctgtc cttccatgaa ggggatgcca tcaccatcct gaggcgcaaa gacgaaaacg
     3421 agaccgagtg gtggtgggct cgtcttgggg accgggaggg ctatgtgccc aaaaacttgc
     3481 ttgggttgta cccacggatc aagccccggc agcggacact tgcctgagcc cctgcagttc
     3541 agtcgtttgc tcccaggaga agcctcccgc tgccctggaa aactgaagcc aggacggtgc
     3601 catggtgctc actttagcag acaggaccca caatgtgaac cccaactccc caggtgaggg
     3661 cctcctcgtc tgcagtggct gggagagcta gtacgtttgc cttcagagga ctgcatttct
     3721 gccaattact gtaaatctga ataaataccc agcttccaaa acatccatcc ctttcgccag
     3781 taagaagtca tgaccatgag ccctgacttg ccaatgaaga caaaagctga cttggcccca
     3841 aggccccttc gtgttaaatg tctgaccttc agcaagagca agctgctgca ggcgacctgg
     3901 gctacccctc cctggaaagt ctcaaaccgt tgtcctttct cacatcgcct ctcacaaaat
     3961 cctttccttt cactaccaaa ggagcccttt tggagactgc tctgtttagt tacctgatga
     4021 cgttctgctg tggctggact cgcacgcctc agcacatggg gctctcggac tcctacggct
     4081 tctagctgca cagcgtccgt catttattct cccctttttg gcataagctc attctattct
     4141 gagtagctaa gacacgggag tctgagcgat aaggagtctt aagttatgtt tgtggtgggc
     4201 tgggcaaagc ccggttcagg atcgacacct gtcaacctga aacgccatcc caagtgaggc
     4261 gggttctgtg tcctggagcc tgagcgctgt agacaggctt tttatacacc agggttactt
     4321 ttcaactagg cctggaaact accaggactg tgttggcaat gtttcttctc atcgaaacac
     4381 aagccttagg ctttattttt catgagtctt gtgcataact acgtgtaaat ccgtgtgggc
     4441 tctgggagca ctgctgtctg tggtcagctg ccaagcggtg atcactcagg gtggcaccaa
     4501 aagtgatgcc ctgtgagcga cctctgccat cccgatgcca ccgatgctgt gtgacgtgca
     4561 caataaaccg ctctctcaca ca
//
