LOCUS       NM_212542               1583 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus protein phosphatase 1, regulatory (inhibitor)
            subunit 11 (Ppp1r11), mRNA.
ACCESSION   NM_212542 XM_215296
VERSION     NM_212542.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1583)
  AUTHORS   McKelvey,A.C., Lear,T.B., Dunn,S.R., Evankovich,J., Londino,J.D.,
            Bednash,J.S., Zhang,Y., McVerry,B.J., Liu,Y. and Chen,B.B.
  TITLE     RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate
            immunity
  JOURNAL   Elife 5, e18496 (2016)
   PUBMED   27805901
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1583)
  AUTHORS   Cheng,L., Pilder,S., Nairn,A.C., Ramdas,S. and Vijayaraghavan,S.
  TITLE     PP1gamma2 and PPP1R11 are parts of a multimeric complex in
            developing testicular germ cells in which their steady state levels
            are reciprocally related
  JOURNAL   PLoS One 4 (3), e4861 (2009)
   PUBMED   19300506
REFERENCE   3  (bases 1 to 1583)
  AUTHORS   Hurt,P., Walter,L., Sudbrak,R., Klages,S., Muller,I., Shiina,T.,
            Inoko,H., Lehrach,H., Gunther,E., Reinhardt,R. and Himmelbauer,H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
REFERENCE   4  (bases 1 to 1583)
  AUTHORS   Coriton,O., Lepourcelet,M., Hampe,A., Galibert,F. and Mosser,J.
  TITLE     Transcriptional analysis of the 69-kb sequence centromeric to
            HLA-J: a dense and complex structure of five genes
  JOURNAL   Mamm Genome 11 (12), 1127-1131 (2000)
   PUBMED   11130983
REFERENCE   5  (bases 1 to 1583)
  AUTHORS   Zhang,J., Zhang,L., Zhao,S. and Lee,E.Y.
  TITLE     Identification and characterization of the human HCG V gene product
            as a novel inhibitor of protein phosphatase-1
  JOURNAL   Biochemistry 37 (47), 16728-16734 (1998)
   PUBMED   9843442
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM088354.1, EX488885.1, BC079252.1 and CX571132.1.
            
            On Oct 17, 2009 this sequence version replaced NM_212542.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM133232.1, BC079252.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                FM088354.1         1-11
            12-31               EX488885.1         6-25
            32-1575             BC079252.1         1-1544
            1576-1583           CX571132.1         641-648
FEATURES             Location/Qualifiers
     source          1..1583
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1583
                     /gene="Ppp1r11"
                     /gene_synonym="HCGV; Tctex5"
                     /note="protein phosphatase 1, regulatory (inhibitor)
                     subunit 11"
                     /db_xref="GeneID:294207"
                     /db_xref="RGD:1303163"
     exon            1..273
                     /gene="Ppp1r11"
                     /gene_synonym="HCGV; Tctex5"
                     /inference="alignment:Splign:2.1.0"
     CDS             202..585
                     /gene="Ppp1r11"
                     /gene_synonym="HCGV; Tctex5"
                     /EC_number="2.3.2.27"
                     /note="protein phosphatase 1 regulatory subunit 11;
                     t-complex testis expressed-5"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase PPP1R11"
                     /protein_id="NP_997707.2"
                     /db_xref="GeneID:294207"
                     /db_xref="RGD:1303163"
                     /translation="MAEAGAGGLSETVTETTVTVTTEPENRSLTIKLRKRKPEKKVEW
                     SSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEDEEEGCGHTHCVRGHRKGRRPT
                     TPGPTPTTPPQPPDPSQPPPGPMQH"
     exon            274..382
                     /gene="Ppp1r11"
                     /gene_synonym="HCGV; Tctex5"
                     /inference="alignment:Splign:2.1.0"
     exon            383..1583
                     /gene="Ppp1r11"
                     /gene_synonym="HCGV; Tctex5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggaagtga aaggccggaa gtggggttgg acaggttttt ccccaggggt ggggaagcag
       61 aggccctgga ggagtagggg agattaagaa gccagagcat cctggcctct actccgaatc
      121 gtgtaccggt tctcttagat ctcagaggcg cagaaaaagg gaggggtgtc tcatcctggt
      181 tcctcgcttt tcgctttagc catggcggag gcaggagccg gggggctgag tgagaccgtc
      241 actgagacaa cggttaccgt gacaaccgag cccgagaatc ggagcctaac cattaaactt
      301 cggaaacgga agccagagaa gaaggtggag tggtcaagtg acactgtgga caatgagcat
      361 atgggccgcc gctcatcgaa atgctgctgt atttatgaga aacctcgggc ctttggtgag
      421 agctccaccg agagtgatga ggatgaagag gaaggctgtg gtcatacgca ctgtgtacgg
      481 ggtcaccgca aaggacggcg tcctacaacc ccaggaccca ccccaaccac tcctccacag
      541 cctcctgatc cctctcagcc ccctccagga cctatgcagc actaaatccc tctcaccatt
      601 catgtgtctg cctggcccca aatgtatcca tctgacatgg ggacttaacc catggtctgg
      661 tcccttctcc cgcccccttc ttccctctcc tgcctgattg agaagaggaa gaggagggcg
      721 gatacagacc ctgtaattct gacttgctgc tgttccagaa cccaggcttt gggttctccc
      781 agccccttct tccctacagt ttgcccctgt gcctgggatc caggcatctt ggtcccaatt
      841 tatccctttt gttctcactg ccaaactacc tgtcctggga tccagttatt ttggccacct
      901 gcaccctcag cttgagtccc aagcacttca actgggtttc caactgtccc agctttcact
      961 gccagggtcc caatcaaatt ccaggcaatc ttgtacccca gctctgcata ttaatcctgg
     1021 cttgtggttc ttccattgac gcagttttcc taaatcttag ttcttgcctg tgggatataa
     1081 ggttgtgtgg agaccatagg gctccctggc ccttctgctc ctcttacccc ttctggctct
     1141 ccagaggagt taggagaggt ctttgtcatt cacacctctg atgggaagtg gaaccaaaag
     1201 tagtcatgtc ttgaatataa catttctgac aaagctagct gagaccactg acctagagtc
     1261 aacgattctc tcagccttta atctttgagc ctcagcattg gtgtcctggc ggccggactc
     1321 cctaaaagga aggagggaga aagcagagag acgaggggac aggcccctgc agtgcactcc
     1381 taccctttcc ttcctaggcc ttggagtctg ccaacccagc tgtcttgctc tctcagcctc
     1441 cccagctggt gctgggacct gggtgttatc ctctaggctc cagctgtgca cagcgcagag
     1501 atcagcaaaa cccacggcac cacttagatc tcatttattg acacagatgc acaaaataaa
     1561 taacccaaca ttgcacaacg tgt
//
