LOCUS       NM_001080783            5667 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus diphosphoinositol pentakisphosphate kinase 1
            (Ppip5k1), mRNA.
ACCESSION   NM_001080783 XM_006234849 XM_230503
VERSION     NM_001080783.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5667)
  AUTHORS   Choi,J.H., Williams,J., Cho,J., Falck,J.R. and Shears,S.B.
  TITLE     Purification, sequencing, and molecular identification of a
            mammalian PP-InsP5 kinase that is activated when cells are exposed
            to hyperosmotic stress
  JOURNAL   J Biol Chem 282 (42), 30763-30775 (2007)
   PUBMED   17702752
REFERENCE   2  (bases 1 to 5667)
  AUTHORS   Fridy,P.C., Otto,J.C., Dollins,D.E. and York,J.D.
  TITLE     Cloning and characterization of two human VIP1-like inositol
            hexakisphosphate and diphosphoinositol pentakisphosphate kinases
  JOURNAL   J Biol Chem 282 (42), 30754-30762 (2007)
   PUBMED   17690096
REFERENCE   3  (bases 1 to 5667)
  AUTHORS   Mulugu,S., Bai,W., Fridy,P.C., Bastidas,R.J., Otto,J.C.,
            Dollins,D.E., Haystead,T.A., Ribeiro,A.A. and York,J.D.
  TITLE     A conserved family of enzymes that phosphorylate inositol
            hexakisphosphate
  JOURNAL   Science 316 (5821), 106-109 (2007)
   PUBMED   17412958
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On or before Aug 4, 2021 this sequence version replaced
            XM_006234849.4, NM_001080783.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.1910218.1,
                                           SRR26360194.2428359.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-149               JAXUCZ010000003.1  128781260-128781408 c
            150-245             JAXUCZ010000003.1  128777086-128777181 c
            246-429             JAXUCZ010000003.1  128776639-128776822 c
            430-625             JAXUCZ010000003.1  128776118-128776313 c
            626-716             JAXUCZ010000003.1  128775627-128775717 c
            717-802             JAXUCZ010000003.1  128775336-128775421 c
            803-957             JAXUCZ010000003.1  128774866-128775020 c
            958-1059            JAXUCZ010000003.1  128774630-128774731 c
            1060-1221           JAXUCZ010000003.1  128773498-128773659 c
            1222-1343           JAXUCZ010000003.1  128773280-128773401 c
            1344-1445           JAXUCZ010000003.1  128768117-128768218 c
            1446-1532           JAXUCZ010000003.1  128767780-128767866 c
            1533-1608           JAXUCZ010000003.1  128767601-128767676 c
            1609-1718           JAXUCZ010000003.1  128767391-128767500 c
            1719-1801           JAXUCZ010000003.1  128767213-128767295 c
            1802-1933           JAXUCZ010000003.1  128766549-128766680 c
            1934-2055           JAXUCZ010000003.1  128766297-128766418 c
            2056-2238           JAXUCZ010000003.1  128765882-128766064 c
            2239-2380           JAXUCZ010000003.1  128762923-128763064 c
            2381-2604           JAXUCZ010000003.1  128762550-128762773 c
            2605-2732           JAXUCZ010000003.1  128762192-128762319 c
            2733-2847           JAXUCZ010000003.1  128761867-128761981 c
            2848-2955           JAXUCZ010000003.1  128761560-128761667 c
            2956-3069           JAXUCZ010000003.1  128760011-128760124 c
            3070-3234           JAXUCZ010000003.1  128759704-128759868 c
            3235-3325           JAXUCZ010000003.1  128757075-128757165 c
            3326-3451           JAXUCZ010000003.1  128753271-128753396 c
            3452-3514           JAXUCZ010000003.1  128752502-128752564 c
            3515-3652           JAXUCZ010000003.1  128747316-128747453 c
            3653-3766           JAXUCZ010000003.1  128743950-128744063 c
            3767-5667           JAXUCZ010000003.1  128737857-128739757 c
FEATURES             Location/Qualifiers
     source          1..5667
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     gene            1..5667
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /note="diphosphoinositol pentakisphosphate kinase 1"
                     /db_xref="GeneID:311355"
                     /db_xref="RGD:1311552"
     exon            1..149
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            150..245
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            246..429
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     CDS             277..4593
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /EC_number="2.7.4.24"
                     /note="PP-IP5 kinase 1; insP6 and PP-IP5 kinase 1;
                     histidine acid phosphatase domain containing 2A; histidine
                     acid phosphatase domain-containing protein 2A; VIP1
                     homolog"
                     /codon_start=1
                     /product="inositol hexakisphosphate and
                     diphosphoinositol-pentakisphosphate kinase 1"
                     /protein_id="NP_001074252.1"
                     /db_xref="GeneID:311355"
                     /db_xref="RGD:1311552"
                     /translation="MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELL
                     EDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVE
                     NWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGID
                     LPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAG
                     GGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARK
                     SPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCD
                     VNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMME
                     LRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDIT
                     RLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQ
                     DLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRL
                     HSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSD
                     SLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFA
                     LIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDI
                     YDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLR
                     KILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLL
                     DETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGV
                     EEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPR
                     RSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLG
                     GSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVP
                     TIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRT
                     LHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEE
                     KQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTI
                     QPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDN
                     PEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGM
                     LTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVPEVVDELSNED
                     IS"
     exon            430..625
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            626..716
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            717..802
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            803..957
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1059
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1221
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1343
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1445
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1532
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1608
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            1609..1718
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            1719..1801
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            1802..1933
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            1934..2055
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            2056..2238
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            2239..2380
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            2381..2604
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            2605..2732
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            2733..2847
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            2848..2955
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            2956..3069
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            3070..3234
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            3235..3325
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            3326..3451
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            3452..3514
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            3515..3652
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            3653..3766
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
     exon            3767..5667
                     /gene="Ppip5k1"
                     /gene_synonym="Hisppd2a; RGD1311552"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccattctga ggctccggcc aacgcagcct gactgttgcc ggtgcgcgcc ctctgcggat
       61 tggtgggacc gcaaagaagt cgcgctttga ttgggccgct gtcaggtgtc gctgccggca
      121 ggttcggctg cgcgagcgga gggaggcggg agtcaacagt agcttccctg aagagcggcc
      181 tcttctcctt gctgcctgga gttgacattg tttcctgccg gcagaatcag tgacatgcca
      241 gccctagcgg gatgactggg tgttccgtca gcggggatgt ggtcattgac ggccaatgag
      301 gacgaggacg agagcgctac ggcccacttc tttcttggag ctggagatga ggggttgggc
      361 acctgtggaa taggcatgag gacaggagag agtgacagtg aactccttga ggacgaggag
      421 gatgaggtgc ccccagaacc tcaaattatt gttggcatct gtgccatgac caagaaatcc
      481 aagtccaagc caatgaccca aatcctagag cggctctgca gatttgacta tctgaccgtt
      541 gtcatcctgg gagaagatgt gatcctaaat gagcccgtgg agaactggcc accctgccac
      601 tgtctcattt ctttccactc caaaggcttt cctctcgaca aagctgttgc ttattccaag
      661 cttcgaaacc ccttccttat caatgatctg accatgcagt attacatcca agacaggagg
      721 gaggtgtacc ggatcctaca ggaggagggt attgatctgc cacgatatgc tgtgctcaac
      781 cgtgaccctg cctgtcctga ggagtgcaac ctgatagaag gtgaagacca ggtggaggtt
      841 aatggagctg tctttcccaa gcccttcgtg gagaagccag tgagtgcaga ggaccacaat
      901 gtttacatct actaccctag ctctgctgga ggaggaagcc agcgcctctt ccgtaagatc
      961 ggcagccgga gcagtgtgta ctctcctgag agcagtgtcc ggaagacagg atcgtacatc
     1021 tatgaggagt tcatgccaac ggatggcaca gacgttaagg tgtacacagt ggggccagat
     1081 tatgcccatg ctgaagctag aaagtctcca gctttggatg ggaaagttga acgagacagt
     1141 gaggggaaag aggttcgata tccagtcatg ttgactgcca tggaaaagct ggtggccagg
     1201 aaggtctgcg tagcttttaa gcaaacagtt tgtggatttg accttcttcg tgccaatggt
     1261 cactcttttg tgtgtgatgt caatggcttt agctttgtca agaactcaat gaagtactat
     1321 gatgactgtg ccaagattct ggggaacacc attatgcggg agcttgcccc acagttccag
     1381 ataccttggt ccatccccac agaagctgag gacattccca ttgtccctac cacatctggc
     1441 actatgatgg aactccgttg tgtcatcgca atcatccgtc acggggaccg aaccccaaag
     1501 cagaagatga agatggaggt gacgcaccca aggttttttg ctctatttga aaaacatggt
     1561 ggatataaga caggaaaatt aaaacttaag cggccagagc agctccagga ggtgctggac
     1621 attacgaggc tgctgttggc tgagctggag aaggaaccag gagctgagat tgaggagaag
     1681 actgggaagc tcgagcagct gaagtctgtg ctggagatgt atggtcactt ctcaggtatt
     1741 aatcggaagg tgcagttgac ctactacccc cacggagtga aagcgtcgag cgagggccaa
     1801 gatctgcaga gagagccacc agcgccatct ctcctgctgg tgctcaagtg gggtggagag
     1861 ctgacacctg atggccgcgt tcaggcagag gagctggggc gggctttccg ttgcatgtat
     1921 cctggaggcc agggtgacta tgctggcttc cctggctgtg ggctgcttcg tctccatagc
     1981 actttccgtc atgacctcaa gatctacgca tctgacgagg gccgcgtcca gatgactgct
     2041 gctgcgtttg caaagggcct cttagctcta gaaggggagc ttacacccat tttggtacaa
     2101 atggtgaaga gcgccaacat gaatgggctg ctggacagcg acagtgactc cctgagcagc
     2161 tgccagcacc gtgtgaaggc acgactgcat cacatcttgc agcaggatgc accctttggc
     2221 cccgaggact atgaccagct ggctccgact ggaagtactt ctctgctcaa ctccatgtct
     2281 gtaatccaga atcctgtgaa agtctgtgat caggtatttg ccctgattga aaaccttacc
     2341 caccaaattc gggaacggat gcaggacccc agctctgtag acctgcagct ctaccacagt
     2401 gaaacactag agctaatgct acagcgttgg agcaaactag agcgtgactt tcgacaaaag
     2461 agcgggcgct atgatatcag taagatcccc gacatctatg actgtgtcaa gtatgatgta
     2521 caacacaatg ggagtctggg acttcaaggc acagccgagt tgctacgtct ttcaaaagct
     2581 ctggccgatg tggtcattcc ccaggaatac ggcatcagta gagaagagaa agtggaaatc
     2641 gctgtgggct tctgccttcc actgctgcgg aaaatcctac ttgacctgca gagaactcac
     2701 gaggatgagt ctgtcaacaa gctgcacccc ctgtactcgc gtggagtgct ctctccaggc
     2761 cgccatgttc gaactcggct ctatttcacc agtgagagcc atgttcactc cctactcagt
     2821 gtcttccgtt atgggggact tctcgatgag accaaggatg cacagtggca gcgagctttg
     2881 gcgtatctta gtgccatctc agagctcaac tacatgaccc agattgttat catgctttat
     2941 gaggacaaca cacgggaccc cttgtcagag gagcggttcc atgtggagct acatttcagc
     3001 cctggtgtga aaggagttga ggaaggcagt gccccagccg gctgtggatt ccgtccagcc
     3061 tcttctgaga acgaggagat gaaaacagat ccaggcagca tagagaacct atgcccagca
     3121 aagccgtcag atgagccaga ccgagccctg cagacctcac cccagcctgt tgagggcact
     3181 ggcctcccga ggagatcacc cctcattcgt aatcgaaaag ctggctccat ggaggtgctg
     3241 tctgaaactt cgtcttcaag acctggtggc tatcggctgt tttcatcttc acggccacca
     3301 acagagatga aacagagcgg cctaggctca cagtgcacag ggctgttcag caccacagtg
     3361 ctgggcggct cctccagtgc tccgaatctt caggactacg cccgcaccca tggcaaaaag
     3421 ctcccgcctg ccggtctaaa gcaccgagat gagctcttgt ttgtcccggc cgtaaaacga
     3481 ttttctgtgt cgtttgcaaa gcatccgact aacggatttg aagggtgctc catggtacct
     3541 accatctacc ccctggaaac actgcacaat gccctttcct tgcgccaagt gagtgaattc
     3601 ttgactaaag tctgccagcg ccacactgat gcccacgcac aggcatctgc agccctcttt
     3661 gactctatgc acaaccacca ggcctcagat aacccgtttt ccccaccccg cactcttcat
     3721 tcgccacccc tgcaacttcg acatcgctct gaaaagccac cttggtacag cagtgggcct
     3781 tccagcactg tgtccagtgc tggcccttcc tctcctacta cggtggatgg aaactcacat
     3841 tttggcttca gtgatcagtc ctctgtaaat acacaaatga ttgaagaaaa gcaaggcctt
     3901 gggttgctcc aggagactcc tggagatgga acaccagagt tccacataga acttgctgag
     3961 tcaacccagt cccctcaaga gccacctgtg gaaatcagcc ctccaggaag tcaggatgat
     4021 actgaggtca accaaacatg ccaggaggtc ccagacacca tccagccatg ccatgacatc
     4081 cttgaggaga ttggccagcc taaccaggag gtccctgaca tcagccagct tttgctgaag
     4141 aaccatgata ctgctaccaa cacgtgtcaa ccatgccagg ccagccagct gtctaagaaa
     4201 gtttatgagg aaatttgtca gctttgtcaa gacaatcctg aggagagtaa ccagctatgc
     4261 caggaagtct cagtagagct gggcaggatg gtccacagat tccctgtaag cattggtagc
     4321 accacccagg aaacccttat ggaaattggc aggccaaccc aagagatccc cgaagaacca
     4381 tgccaggagt tctctgagaa ggttggcatg ctgactcaga aagcctctgc catcagtgag
     4441 ttatctcaag acatccttga gactgacaat ccttcccaag agctctctga ggagactgat
     4501 ctacaggctc aggaagtctc tgaggagatt gatcaggagc ccgaggtggt ccctgaggtg
     4561 gttgatgagc tgtctaatga agatatctcc taagttcaat atctgactag tgatataaac
     4621 actgaaagcc agtctccggc tcacaaccag cactcagccc ttccaccagc aacatgtgac
     4681 tagtcatctt gttattggtg tcctactcta ccagctattt gagccaacag cctttctgtt
     4741 ggctaacaca cagagcccca agcaaggtgt gggctcacac agcagtgtct gaggaaatag
     4801 gccttgtggc atgaaacata ctcctgccag agcttacgcc taaggaggag ctgtttatgt
     4861 tcagagaagt tgttggctgt tcacttagcc atggagttgg gaatcataga ttgttgaagg
     4921 aaatgccact taactgctga agataccatg ttgaagggac agcaaatata acatggaagg
     4981 tggcagggtc tctacttgtt gaatgaaata ttcacaactt tttaaggtac cctctgccca
     5041 tatgtgcatt caaggaaact cttcactctc acaggctagc tcaggggaac tgcctgagat
     5101 gtctggaaaa tagagttcca ctgtctaaac tcatggttga gactgagctt atggatgttt
     5161 tgatgtaatt gccaagtgct tccctgccta gtcctcgtcc tgtggacatc agctctagaa
     5221 gaaaattgat attagattgc catgcaactt cagagtgact acttagaatg ctctgggaga
     5281 tttgcatcaa tctatgaagc caggcctcct tttcttgtga ggctattggg cttagaagat
     5341 gctgtaatag agagaatcaa gttctatttt aaacaattag cagagatcaa tgttgtacag
     5401 acatgagcaa agatttaata tatatatata tatatatata tataaacata tatatttctg
     5461 tagtttgcca gggacagagt ggccaaagat caaacactcc agggtcccca agaggtttgt
     5521 ccttatatca tgtgtctttg tgaccgtatg tgattatgaa gcttttccca aagatctagg
     5581 gataggagtg ggcataggta atgcagtcat tggagtgggg gaggggggac atgacgagtg
     5641 ctcaataaac aaaataatga gaacgag
//
